Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways.

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Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal (2012) 5.65

Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol (2004) 2.46

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation. Br J Cancer (2004) 1.68

Redox mechanisms in hepatic chronic wound healing and fibrogenesis. Fibrogenesis Tissue Repair (2008) 1.30

Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells. Biochem J (2005) 1.22

Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. Biochem J (2007) 1.16

Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol Cell Biol (2009) 1.13

Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization. Am J Respir Cell Mol Biol (2012) 1.11

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments. Assay Drug Dev Technol (2010) 1.10

Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study. J Neuroinflammation (2006) 1.06

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Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation. Free Radic Biol Med (2007) 1.05

Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance. Adv Enzyme Regul (2007) 1.01

SHP-1 inhibition by 4-hydroxynonenal activates Jun N-terminal kinase and glutamate cysteine ligase. Am J Respir Cell Mol Biol (2008) 1.01

Oxidative stress and redox modulation potential in type 1 diabetes. Clin Dev Immunol (2011) 1.00

Redox cycling compounds generate H2O2 in HTS buffers containing strong reducing reagents--real hits or promiscuous artifacts? Curr Opin Chem Biol (2010) 0.98

Reactive oxygen species and vascular remodelling in hypertension: still alive. Can J Cardiol (2006) 0.98

Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase. Blood (2005) 0.97

Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP. Proc Natl Acad Sci U S A (2010) 0.96

Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation. Am J Respir Cell Mol Biol (2008) 0.94

Cigarette smoke extract stimulates epithelial-mesenchymal transition through Src activation. Free Radic Biol Med (2012) 0.92

MICAL-family proteins: Complex regulators of the actin cytoskeleton. Antioxid Redox Signal (2013) 0.92

Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking. Purinergic Signal (2009) 0.91

Nucleotide receptor signalling and the generation of reactive oxygen species. Purinergic Signal (2007) 0.89

β3 integrin promotes TGF-β1/H2O2/HOCl-mediated induction of metastatic phenotype of hepatocellular carcinoma cells by enhancing TGF-β1 signaling. PLoS One (2013) 0.87

Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. Free Radic Biol Med (2013) 0.85

The Effect of Cigarette Smoke-derived Oxidants on the Inflammatory Response of the Lung. Clin Appl Immunol Rev (2006) 0.83

Redox signaling in acute pancreatitis. Redox Biol (2015) 0.82

Clinical review: oxygen as a signaling molecule. Crit Care (2010) 0.81

Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation. J Immunol (2010) 0.81

The effects of nitroxyl (HNO) on H₂O₂ metabolism and possible mechanisms of HNO signaling. Arch Biochem Biophys (2013) 0.80

Oxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61. J Neurochem (2011) 0.80

Negative regulation of inflammatory responses by immunoglobulin A receptor (FcαRI) inhibits the development of Toll-like receptor-9 signalling-accelerated glomerulonephritis. Clin Exp Immunol (2011) 0.80

Sodium ferulate inhibits neointimal hyperplasia in rat balloon injury model. PLoS One (2014) 0.79

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells. PLoS One (2014) 0.78

Reactive oxygen species-mediated therapeutic control of bladder cancer. Nat Rev Urol (2011) 0.78

Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2. Oncotarget (2016) 0.77

Vanadium Compounds as Pro-Inflammatory Agents: Effects on Cyclooxygenases. Int J Mol Sci (2015) 0.76

Intracellular IL-37b interacts with Smad3 to suppress multiple signaling pathways and the metastatic phenotype of tumor cells. Oncogene (2017) 0.75

Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib. Oncotarget (2017) 0.75

Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family. J Virol (2006) 2.63

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock. J Exp Med (2009) 1.68

Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci (2005) 1.32

Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci (2003) 1.16

Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid. Invest Ophthalmol Vis Sci (2007) 1.07

The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models. Diabetes (2011) 0.97

Inhibition of cytokine signaling in human retinal endothelial cells through downregulation of sphingomyelinases by docosahexaenoic acid. Invest Ophthalmol Vis Sci (2010) 0.95

Complementary precursor ion and neutral loss scan mode tandem mass spectrometry for the analysis of glycerophosphatidylethanolamine lipids from whole rat retina. Anal Bioanal Chem (2009) 0.88

Examining the role of lipid mediators in diabetic retinopathy. Clin Lipidol (2012) 0.86

Substrate conformational restriction and CD45-catalyzed dephosphorylation of tail tyrosine-phosphorylated Src protein. J Biol Chem (2002) 0.85

Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC. J Biol Chem (2005) 0.78