Published in Toxicol Appl Pharmacol on September 15, 2002
The autoimmune regulator prevents premature reproductive senescence in female mice. Biol Reprod (2012) 1.42
Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line. Biochem Biophys Res Commun (2003) 1.25
Lithium suppresses cell proliferation by interrupting E2F-DNA interaction and subsequently reducing S-phase gene expression in prostate cancer. Prostate (2007) 1.14
GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. J Cell Sci (2010) 1.12
Ovarian endocrine disruption underlies premature reproductive senescence following environmentally relevant chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biol Reprod (2006) 1.02
Reduction in proliferation with six months of letrozole in women on hormone replacement therapy. Breast Cancer Res Treat (2007) 1.01
Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons. J Neurochem (2003) 0.98
Alteration in ovarian gene expression in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin: reduction of cyclooxygenase-2 in the blockage of ovulation. Reprod Toxicol (2002) 0.95
Conditional Akt activation promotes androgen-independent progression of prostate cancer. Carcinogenesis (2006) 0.93
Tumor necrosis factor-alpha induces serum amyloid A3 in mouse granulosa cells. Endocrinology (2004) 0.93
Discovery and development of the covalent hydrates of trifluoromethylated pyrazoles as riboflavin synthase inhibitors with antibiotic activity against Mycobacterium tuberculosis. J Org Chem (2009) 0.93
Effects of acute and chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin on the transition to reproductive senescence in female Sprague-Dawley rats. Biol Reprod (2005) 0.93
Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study. Int J Cancer (2010) 0.92
The aryl hydrocarbon receptor is required for normal gonadotropin responsiveness in the mouse ovary. Toxicol Appl Pharmacol (2007) 0.91
Characterization of a preclinical model of simultaneous breast and ovarian cancer progression. Carcinogenesis (2006) 0.91
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin (HxCDD) alter body weight by decreasing insulin-like growth factor I (IGF-I) signaling. Toxicol Sci (2005) 0.90
Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors. J Mol Neurosci (2003) 0.89
Tumor necrosis factor alpha (TNF) increases granulosa cell proliferation: dependence on c-Jun and TNF receptor type 1. Endocrinology (2003) 0.88
Endocrine disruption: fact or urban legend? Toxicol Lett (2013) 0.87
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces plasminogen activator inhibitor-1 through an aryl hydrocarbon receptor-mediated pathway in mouse hepatoma cell lines. Arch Toxicol (2002) 0.87
Syngeneic mouse model of epithelial ovarian cancer: effects of nanoparticulate paclitaxel, Nanotax. Adv Exp Med Biol (2008) 0.87
Tamoxifen decreases ovarian follicular loss from experimental toxicant DMBA and chemotherapy agents cyclophosphamide and doxorubicin in the rat. J Assist Reprod Genet (2010) 0.87
Tumor necrosis factor (TNF) receptor type 2 is an important mediator of TNF alpha function in the mouse ovary. Biol Reprod (2006) 0.85
Tamoxifen prevents premalignant changes of breast, but not ovarian, cancer in rats at high risk for both diseases. Cancer Prev Res (Phila) (2008) 0.85
A high-throughput screen utilizing the fluorescence of riboflavin for identification of lumazine synthase inhibitors. Anal Biochem (2005) 0.84
Favorable modulation of benign breast tissue and serum risk biomarkers is associated with > 10 % weight loss in postmenopausal women. Breast Cancer Res Treat (2013) 0.84
The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo. BMC Dev Biol (2008) 0.83
Reduction in Ki-67 in benign breast tissue of high-risk women with the lignan secoisolariciresinol diglycoside. Cancer Prev Res (Phila) (2010) 0.82
Effect of chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rats on ovarian gene expression. Reprod Toxicol (2009) 0.82
Interaction of adenosine 3',5'-cyclic monophosphate and tumor necrosis factor-alpha on serum amyloid A3 expression in mouse granulosa cells: dependence on CCAAT-enhancing binding protein-beta isoform. Endocrinology (2010) 0.82
Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression. Prostate (2008) 0.82
From dioxin to drug lead--the development of 2,3,7,8-tetrachlorophenothiazine. ChemMedChem (2007) 0.81
Assessment of RNA in human breast tissue sampled by random periareolar fine needle aspiration and ductal lavage and processed as fixed or frozen specimens. Reprod Biol (2013) 0.81
Digital chemistry in the Journal of Medicinal Chemistry. J Med Chem (2014) 0.81
Src tyrosine kinase regulates CYP17 expression and androstenedione secretion in theca-enriched mouse ovarian cells. Endocrine (2004) 0.81
Amyloid peptide toxicity and microtubule-stabilizing drugs. J Mol Neurosci (2002) 0.81
Potential roles of the aryl hydrocarbon receptor in female reproductive senescence. Reprod Biol (2004) 0.81
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reverses hyperglycemia in a type II diabetes mellitus rat model by a mechanism unrelated to PPAR gamma. Drug Chem Toxicol (2010) 0.80
Tissue-specific effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activity of 5'-deiodinases I and II in rats. Toxicol Lett (2004) 0.80
Alterations in reproductive function in SRC tyrosine kinase knockout mice. Endocrine (2005) 0.80
Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. Toxicology (2005) 0.79
The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disturbs the establishment and maintenance of cell polarity in preimplantation rat embryos. Biol Reprod (2010) 0.79
The Src tyrosine kinase pathway regulates thecal CYP17 expression and androstenedione secretion. Mol Cell Biochem (2008) 0.79
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reprod Toxicol (2002) 0.78
Discovery and development of a small molecule library with lumazine synthase inhibitory activity. J Org Chem (2009) 0.78
Protein kinase C delta is activated in mouse ovarian surface epithelial cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicology (2004) 0.78
Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations. Toxicol Sci (2003) 0.78
High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma. PLoS One (2013) 0.78
Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line. Toxicology (2002) 0.76
Effects of Flaxseed Lignan Secoisolariciresinol Diglucosideon Preneoplastic Biomarkers of Cancer Progression in a Model of Simultaneous Breast and Ovarian Cancer Development. Nutr Cancer (2015) 0.76
The combined effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phytoestrogen genistein on steroid hormone secretion, AhR and ERβ expression and the incidence of apoptosis in granulosa cells of medium porcine follicles. J Reprod Dev (2015) 0.75
Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol Appl Pharmacol (2004) 0.75
Letter to the editor regarding Bailey article. Chem Res Toxicol (2009) 0.75
From more to less than Haber's law. Environ Toxicol Pharmacol (2002) 0.75
Rebuttal to Haseman. Threshold extrapolation in chemical carcinogenesis. Toxicol Pathol (2003) 0.75
Thresholds in carcinogenicity in ED01 study. Toxicol Sci (2003) 0.75
Tumor necrosis factor alpha (TNF) suppresses cAMP response element (CRE) activity and nuclear CRE binding protein in MA-10 mouse Leydig tumor cells. Endocrine (2005) 0.75
Serous cysts are a benign component of the cyclic ovary in the guinea pig with an incidence dependent upon inhibin bioactivity. J Vet Med Sci (2002) 0.75
Epigenetics: novel therapeutics targeting epigenetics. J Med Chem (2014) 0.75
Relationship between aryl hydrocarbon receptor-affinity and the induction of EROD activity by 2,3,7,8-tetrachlorinated phenothiazine and derivatives. Toxicol Appl Pharmacol (2007) 0.75