Published in Am J Physiol Endocrinol Metab on September 24, 2002
Testosterone and growth hormone improve body composition and muscle performance in older men. J Clin Endocrinol Metab (2009) 1.40
Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men. J Am Geriatr Soc (2008) 1.13
Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? Endocr Rev (2012) 1.01
The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci (2012) 0.96
25(OH) vitamin D is associated with greater muscle strength in healthy men and women. Med Sci Sports Exerc (2013) 0.89
Effect of oral anabolic steroid on muscle strength and muscle growth in hemodialysis patients. Clin J Am Soc Nephrol (2012) 0.84
The use of anabolic steroids as a strategy in reversing denervation atrophy after delayed nerve repair. Hand (N Y) (2011) 0.77
Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies. Age (Dordr) (2015) 0.76
Effects of Testosterone Supplementation for 3-Years on Muscle Performance and Physical Function in Older Men. J Clin Endocrinol Metab (2016) 0.75
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Adverse events associated with testosterone administration. N Engl J Med (2010) 10.94
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc (2011) 5.96
Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction: a parallel, randomized trial. Ann Intern Med (2012) 4.18
Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst (2006) 4.17
Stage at diagnosis is a key explanation of differences in breast cancer survival across Europe. Int J Cancer (2003) 3.89
Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Lancet (2003) 3.53
Clinical review 1: Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis. J Clin Endocrinol Metab (2010) 3.40
Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials. J Gerontol A Biol Sci Med Sci (2005) 3.14
Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Int J Cancer (2006) 2.89
Risks and benefits of testosterone therapy in older men. Nat Rev Endocrinol (2013) 2.47
Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle. J Clin Endocrinol Metab (2004) 2.47
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci U S A (2004) 2.41
Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc (2011) 2.34
Air pollution and risk of lung cancer in a prospective study in Europe. Int J Cancer (2006) 2.17
Metabolic and reproductive features before and during puberty in daughters of women with polycystic ovary syndrome. J Clin Endocrinol Metab (2009) 2.08
Effects of testosterone replacement in men with opioid-induced androgen deficiency: a randomized controlled trial. Pain (2015) 2.01
Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am J Physiol Endocrinol Metab (2003) 1.98
Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2004) 1.91
Ascertainment of Testosterone Prescribing Practices in the VA. Med Care (2015) 1.89
High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden. J Am Coll Cardiol (2011) 1.81
Effects of graded doses of testosterone on erythropoiesis in healthy young and older men. J Clin Endocrinol Metab (2007) 1.77
Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology (2003) 1.74
Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. Am J Physiol Endocrinol Metab (2003) 1.74
Ventilatory efficiency during exercise in healthy subjects. Am J Respir Crit Care Med (2002) 1.71
Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals. Am J Cardiol (2011) 1.65
Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging. Nat Clin Pract Endocrinol Metab (2006) 1.63
Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study. J Clin Endocrinol Metab (2010) 1.62
Targeting the skeletal muscle-metabolism axis in prostate-cancer therapy. N Engl J Med (2012) 1.61
Influence of sex and hormone status on circulating natriuretic peptides. J Am Coll Cardiol (2011) 1.61
Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease. Gastroenterology (2003) 1.58
Testosterone dose-dependently increases maximal voluntary strength and leg power, but does not affect fatigability or specific tension. J Clin Endocrinol Metab (2003) 1.57
Plasma phospholipid fatty acid profiles and their association with food intakes: results from a cross-sectional study within the European Prospective Investigation into Cancer and Nutrition. Am J Clin Nutr (2008) 1.57
Physical activity and risk of colon and rectal cancers: the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev (2006) 1.56
Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells. Endocrinology (2005) 1.56
Influence of hormone replacement therapy on eccentric exercise induced myogenic gene expression in postmenopausal women. J Appl Physiol (1985) (2009) 1.55
Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst (2006) 1.55
Testosterone-induced increase in muscle size in healthy young men is associated with muscle fiber hypertrophy. Am J Physiol Endocrinol Metab (2002) 1.54
Satellite cell numbers in young and older men 24 hours after eccentric exercise. Muscle Nerve (2006) 1.52
Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc (2010) 1.51
Breast cancer risk in relation to abortion: Results from the EPIC study. Int J Cancer (2006) 1.51
Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients. Kidney Int (2005) 1.51
Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies. J Clin Endocrinol Metab (2011) 1.50
DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination. Mitochondrion (2009) 1.50
Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes (2007) 1.50
Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis. J Clin Endocrinol Metab (2010) 1.50
Survival from rare cancer in adults: a population-based study. Lancet Oncol (2006) 1.49
Testosterone supplementation of megestrol therapy does not enhance lean tissue accrual in men with human immunodeficiency virus-associated weight loss: a randomized, double-blind, placebo-controlled, multicenter trial. J Clin Endocrinol Metab (2006) 1.49
Effects of a supraphysiological dose of testosterone on physical function, muscle performance, mood, and fatigue in men with HIV-associated weight loss. Am J Physiol Endocrinol Metab (2008) 1.46
The Testosterone Trials: Seven coordinated trials of testosterone treatment in elderly men. Clin Trials (2014) 1.46
Genetic determinants of serum testosterone concentrations in men. PLoS Genet (2011) 1.45
Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma. Blood (2009) 1.45
Effect of testosterone administration on liver fat in older men with mobility limitation: results from a randomized controlled trial. J Gerontol A Biol Sci Med Sci (2013) 1.44
Androgen supplementation in older women: too much hype, not enough data. J Am Geriatr Soc (2002) 1.43
Anthropometric measures, endogenous sex steroids and breast cancer risk in postmenopausal women: a study within the EPIC cohort. Int J Cancer (2006) 1.43
Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci (2011) 1.43
Smoking and the risk of gastric cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC). Int J Cancer (2003) 1.42
Single-port access: a feasible alternative to conventional laparoscopic splenectomy. Surg Innov (2009) 1.41
Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study. Environ Health (2007) 1.41
Testosterone and growth hormone improve body composition and muscle performance in older men. J Clin Endocrinol Metab (2009) 1.40
Serum androgen levels in black, Hispanic, and white men. J Clin Endocrinol Metab (2006) 1.40
Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. Am J Clin Nutr (2007) 1.40
Physical activity and breast cancer risk: the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev (2006) 1.38
The Maternal Phenylketonuria International Study: 1984-2002. Pediatrics (2003) 1.37
Tests of muscle strength and physical function: reliability and discrimination of performance in younger and older men and older men with mobility limitations. J Am Geriatr Soc (2008) 1.37
Androgen receptor in human skeletal muscle and cultured muscle satellite cells: up-regulation by androgen treatment. J Clin Endocrinol Metab (2004) 1.36
Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis (2008) 1.36
Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement. Endocr Rev (2013) 1.33
Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men. Am J Physiol Endocrinol Metab (2003) 1.33
Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer (2007) 1.33
The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways. J Biol Chem (2008) 1.32
Testosterone action on skeletal muscle. Curr Opin Clin Nutr Metab Care (2004) 1.32
Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men. J Clin Endocrinol Metab (2006) 1.31
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet (2011) 1.30
Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men. J Clin Endocrinol Metab (2005) 1.28
Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer (2006) 1.25
Association between testosterone and estradiol and age-related decline in physical function in a diverse sample of men. J Am Geriatr Soc (2008) 1.24
Testosterone, sex hormone-binding globulin, and frailty in older men. J Am Geriatr Soc (2007) 1.24
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
Exercise in maintenance hemodialysis patients induces transcriptional changes in genes favoring anabolic muscle. J Am Soc Nephrol (2007) 1.21
Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men. J Clin Endocrinol Metab (2004) 1.21
Amount of DNA in plasma and cancer risk: a prospective study. Int J Cancer (2004) 1.21