Published in Development on November 01, 2002
Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci U S A (2006) 3.89
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PLoS One (2011) 2.86
Holoprosencephaly. Orphanet J Rare Dis (2007) 2.63
Early steps in the development of the forebrain. Dev Cell (2004) 2.34
Relations and interactions between cranial mesoderm and neural crest populations. J Anat (2005) 2.26
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell (2008) 1.57
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A (2006) 1.53
Proposal of a model of mammalian neural induction. Dev Biol (2007) 1.42
Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. Elife (2013) 1.33
Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med (2012) 1.27
BMPs and chordin regulate patterning of the directive axis in a sea anemone. Proc Natl Acad Sci U S A (2009) 1.24
Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development. Dev Biol (2007) 1.20
Site-1 protease is required for cartilage development in zebrafish. Proc Natl Acad Sci U S A (2003) 1.15
Pathogenesis of holoprosencephaly. J Clin Invest (2009) 1.12
The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol (2006) 1.11
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation. Dev Neurobiol (2012) 1.10
Sog/Chordin is required for ventral-to-dorsal Dpp/BMP transport and head formation in a short germ insect. Proc Natl Acad Sci U S A (2006) 1.07
Noggin regulates Bmp4 activity during pituitary induction. Dev Biol (2007) 1.03
Holoprosencephaly and agnathia spectrum: Presentation of two new patients and review of the literature. Am J Med Genet C Semin Med Genet (2010) 1.01
Dkk1 and noggin cooperate in mammalian head induction. Genes Dev (2003) 1.00
Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression. Dev Cell (2011) 0.98
The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol (2006) 0.96
Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development. Genesis (2009) 0.96
Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development (2015) 0.93
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease. Bone Res (2016) 0.88
Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans. Wiley Interdiscip Rev Dev Biol (2014) 0.88
Identification and characterization of an injury-induced skeletal progenitor. Proc Natl Acad Sci U S A (2015) 0.87
MiR-30e and miR-181d control radial glia cell proliferation via HtrA1 modulation. Cell Death Dis (2012) 0.87
Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice. Arch Oral Biol (2005) 0.86
Roles of bone morphogenetic protein signaling and its antagonism in holoprosencephaly. Am J Med Genet C Semin Med Genet (2010) 0.85
Initiating head development in mouse embryos: integrating signalling and transcriptional activity. Open Biol (2012) 0.84
BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. Hum Mol Genet (2010) 0.84
Smad1 and Smad8 function similarly in mammalian central nervous system development. Mol Cell Biol (2005) 0.83
Myo/Nog cell regulation of bone morphogenetic protein signaling in the blastocyst is essential for normal morphogenesis and striated muscle lineage specification. Dev Biol (2011) 0.83
The expression of twisted gastrulation in postnatal mouse brain and functional implications. Neuroscience (2010) 0.82
Regulation of pre-otic brain development by the cephalic neural crest. Proc Natl Acad Sci U S A (2009) 0.82
Molecular regulation of striatal development: a review. Anat Res Int (2012) 0.82
Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons. Dev Dyn (2011) 0.81
BMP signaling dynamics in embryonic orofacial tissue. J Cell Physiol (2008) 0.81
β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis. BMC Dev Biol (2016) 0.81
BMP signaling in telencephalic neural cell specification and maturation. Front Cell Neurosci (2013) 0.80
Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice. Dis Model Mech (2014) 0.78
NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos. Dis Model Mech (2012) 0.78
Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. Dev Biol (2014) 0.78
Minimal evidence for a direct involvement of twisted gastrulation homolog 1 (TWSG1) gene in human holoprosencephaly. Mol Genet Metab (2010) 0.76
Pluripotent stem cell studies elucidate the underlying mechanisms of early embryonic development. Genes (Basel) (2011) 0.76
Molecular mechanisms of midfacial developmental defects. Dev Dyn (2015) 0.75
Molecular analysis of the Noggin (NOG) gene in holoprosencephaly patients. Mol Genet Metab (2012) 0.75
BMPR1B mutation causes Pierre Robin sequence. Oncotarget (2017) 0.75
Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury. Stem Cells Int (2016) 0.75
Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma. Neoplasia (2017) 0.75
Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders. Cytokine Growth Factor Rev (2015) 0.75
Regulation of pituitary stem cells by epithelial to mesenchymal transition events and signaling pathways. Mol Cell Endocrinol (2016) 0.75
Cordon-bleu is an actin nucleation factor and controls neuronal morphology. Cell (2007) 2.79
Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. Differentiation (2006) 2.04
Fgf8 is required for anterior heart field development. Development (2006) 2.03
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development (2004) 1.93
Mutation mapping and identification by whole-genome sequencing. Genome Res (2012) 1.51
The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol (2004) 1.45
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development (2008) 1.45
Cordon-bleu is a conserved gene involved in neural tube formation. Dev Biol (2003) 1.44
Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development. Development (2007) 1.43
Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected]. Development (2003) 1.38
Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart. Development (2008) 1.37
Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. Dev Biol (2010) 1.34
The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development (2003) 1.29
Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development (2007) 1.27
The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis. Circ Res (2007) 1.19
BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning. Dev Biol (2004) 1.18
Mutations in TBX1 genocopy the 22q11.2 deletion and duplication syndromes: a new susceptibility factor for mental retardation. Eur J Hum Genet (2007) 1.10
RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. Neuron (2011) 1.05
BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. Development (2008) 1.04
Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn (2006) 1.02
BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites. Development (2006) 0.98
The actin nucleator Cordon-bleu is required for development of motile cilia in zebrafish. Dev Biol (2010) 0.97
Chordin is a modifier of tbx1 for the craniofacial malformations of 22q11 deletion syndrome phenotypes in mouse. PLoS Genet (2009) 0.97
The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol (2006) 0.96
Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis. Evol Dev (2002) 0.95
SNP2RFLP: a computational tool to facilitate genetic mapping using benchtop analysis of SNPs. Mamm Genome (2008) 0.93
Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway. J Mol Cell Cardiol (2010) 0.92
Roles of organizer factors and BMP antagonism in mammalian forebrain establishment. Dev Biol (2006) 0.90
Optimized protocol for derivation of human embryonic stem cell lines. Stem Cell Rev (2012) 0.88
Abnormal venous and arterial patterning in Chordin mutants. Dev Dyn (2007) 0.88
BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. Hum Mol Genet (2010) 0.84
Compartmentalization of the foregut tube: developmental origins of the trachea and esophagus. Wiley Interdiscip Rev Dev Biol (2011) 0.84
One shall become two: Separation of the esophagus and trachea from the common foregut tube. Dev Dyn (2014) 0.82
Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons. Dev Dyn (2011) 0.81
Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile. Wiley Interdiscip Rev Syst Biol Med (2012) 0.81
Tracheal oxalosis associated with Aspergillus niger tracheobronchitis. Eur Respir J (2013) 0.78
A novel mutation in the gene encoding noggin is not causative in human neural tube defects. J Neurogenet (2002) 0.77
Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. Dev Dyn (2015) 0.76
IV delivery of fluorescent beads. Chest (2012) 0.75