Published in J Cell Biol on October 28, 2002
Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature (2009) 4.44
Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73
The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities. Biophys J (2004) 1.98
Single-channel SCAM identifies pore-lining residues in the first extracellular loop and first transmembrane domains of Cx46 hemichannels. J Gen Physiol (2003) 1.87
Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule. Proc Natl Acad Sci U S A (2007) 1.86
Gap junction channel structure in the early 21st century: facts and fantasies. Curr Opin Cell Biol (2007) 1.40
Gap-junction channels dysfunction in deafness and hearing loss. Antioxid Redox Signal (2009) 1.39
The role of connexins in ear and skin physiology - functional insights from disease-associated mutations. Biochim Biophys Acta (2012) 1.34
SCAM analysis of Panx1 suggests a peculiar pore structure. J Gen Physiol (2010) 1.25
Charges dispersed over the permeation pathway determine the charge selectivity and conductance of a Cx32 chimeric hemichannel. J Physiol (2008) 1.20
Role of the N-terminus in permeability of chicken connexin45.6 gap junctional channels. J Physiol (2006) 1.20
Conformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel. J Gen Physiol (2009) 1.18
Cardiac conduction is required to preserve cardiac chamber morphology. Proc Natl Acad Sci U S A (2010) 1.17
A transient diffusion model yields unitary gap junctional permeabilities from images of cell-to-cell fluorescent dye transfer between Xenopus oocytes. Biophys J (2004) 1.05
Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. J Mol Biol (2010) 1.05
Conductance of connexin hemichannels segregates with the first transmembrane segment. Biophys J (2005) 1.00
Voltage-dependent conformational changes in connexin channels. Biochim Biophys Acta (2011) 0.99
Pore-lining residues identified by single channel SCAM studies in Cx46 hemichannels. Cell Commun Adhes (2003) 0.98
Analysis of four connexin26 mutant gap junctions and hemichannels reveals variations in hexamer stability. Biophys J (2010) 0.96
The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates. J Membr Biol (2012) 0.93
Molecular modeling and mutagenesis of gap junction channels. Prog Biophys Mol Biol (2007) 0.90
A fully atomistic model of the Cx32 connexon. PLoS One (2008) 0.90
Cosegregation of permeability and single-channel conductance in chimeric connexins. Biophys J (2005) 0.88
Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system? Front Pharmacol (2013) 0.87
Novel mutations in GJA1 cause oculodentodigital syndrome. J Dent Res (2008) 0.87
Replacement of a single cysteine in the fourth transmembrane region of zebrafish pannexin 1 alters hemichannel gating behavior. Exp Brain Res (2009) 0.82
Characterization of a novel water pocket inside the human Cx26 hemichannel structure. Biophys J (2014) 0.80
Site-directed mutagenesis reveals putative regions of protein interaction within the transmembrane domains of connexins. Cell Commun Adhes (2008) 0.79
Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal). Biophys J (2011) 0.79
Antibodies targeting extracellular domain of connexins for studies of hemichannels. Neuropharmacology (2013) 0.79
Gating on the outside. J Gen Physiol (2009) 0.77
Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem (2015) 0.75
Connexinopathies: a structural and functional glimpse. BMC Cell Biol (2016) 0.75
Accessing gap-junction channel structure-function relationships through molecular modeling and simulations. BMC Cell Biol (2017) 0.75
Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene (1989) 60.30
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
The open pore conformation of potassium channels. Nature (2002) 9.09
Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol (1986) 4.69
Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes. J Cell Biol (1991) 4.47
Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J Cell Biol (1995) 4.08
Three-dimensional structure of a recombinant gap junction membrane channel. Science (1999) 3.69
Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit. Neuron (1994) 3.44
Gap junctions formed by connexins 26 and 32 alone and in combination are differently affected by applied voltage. Proc Natl Acad Sci U S A (1991) 3.19
Structure and biochemistry of mouse hepatic gap junctions. J Mol Biol (1979) 2.44
Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations. EMBO J (1988) 2.26
The first extracellular loop domain is a major determinant of charge selectivity in connexin46 channels. Biophys J (2000) 2.20
Unique and redundant connexin contributions to lens development. Science (2002) 2.17
Molecular determinants of electrical rectification of single channel conductance in gap junctions formed by connexins 26 and 32. J Gen Physiol (1999) 2.16
Changes in permeability caused by connexin 32 mutations underlie X-linked Charcot-Marie-Tooth disease. Neuron (1997) 2.15
Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10
Isoform composition of connexin channels determines selectivity among second messengers and uncharged molecules. J Biol Chem (1998) 2.08
Size and selectivity of gap junction channels formed from different connexins. J Bioenerg Biomembr (1996) 2.00
Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells. EMBO J (1994) 1.83
The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions. Biophys J (1999) 1.82
Selective transfer of endogenous metabolites through gap junctions composed of different connexins. Nat Cell Biol (1999) 1.80
Identification of a proline residue as a transduction element involved in voltage gating of gap junctions. Nature (1993) 1.79
Identification of a pore lining segment in gap junction hemichannels. Biophys J (1997) 1.69
Innexins get into the gap. Bioessays (2001) 1.60
Structure of gap junction intercellular channels. Curr Opin Struct Biol (1996) 1.60
Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels. Biophys J (1999) 1.38
Altered formation of hemichannels and gap junction channels caused by C-terminal connexin-32 mutations. J Neurosci (1999) 1.34
Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors. Biophys J (1999) 1.32
Evidence for fixed charge in the nexus. Nature (1980) 1.30
Buried charged surface in proteins. Structure (2000) 1.26
The molecular basis of selective permeability of connexins is complex and includes both size and charge. Braz J Med Biol Res (2000) 1.22
Human diseases: clues to cracking the connexin code? Trends Cell Biol (2001) 1.11
Effects of aromatic residues at the ends of transmembrane alpha-helices on helix interactions with lipid bilayers. Biochemistry (2000) 1.04
Connexin genes in the mouse and human genome. Cell Commun Adhes (2001) 0.96
The influence of surface charges on the conductance of the human connexin37 gap junction channel. Biophys J (2000) 0.95
Applying the Xenopus oocyte expression system to the analysis of gap junction proteins. Methods Mol Biol (2001) 0.89
Elastic behavior of cross-linked and bundled actin networks. Science (2004) 5.44
Gap junctions formed by connexins 26 and 32 alone and in combination are differently affected by applied voltage. Proc Natl Acad Sci U S A (1991) 3.19
Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA. J Cell Biol (1989) 2.74
Ultrasonographic elastography of thyroid nodules: is adding strain ratio to colour mapping better? Clin Radiol (2013) 2.71
Application of bone marrow samples for discrimination of acute promyelocytic leukemia from other types of acute leukemia using the routine automated hematology analyzer. Int J Lab Hematol (2014) 2.63
Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T. Biochemistry (1995) 2.31
Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. Biophys J (2004) 2.02
Acute abdominal pain in systemic lupus erythematosus: focus on lupus enteritis (gastrointestinal vasculitis). Ann Rheum Dis (2002) 1.83
Selective transfer of endogenous metabolites through gap junctions composed of different connexins. Nat Cell Biol (1999) 1.80
Identification of a proline residue as a transduction element involved in voltage gating of gap junctions. Nature (1993) 1.79
Structure of tetraubiquitin shows how multiubiquitin chains can be formed. J Mol Biol (1994) 1.76
The pattern of disulfide linkages in the extracellular loop regions of connexin 32 suggests a model for the docking interface of gap junctions. J Cell Biol (1998) 1.73
Differences between liver gap junction protein and lens MIP 26 from rat: implications for tissue specificity of gap junctions. Cell (1983) 1.65
Structure of gap junction intercellular channels. Curr Opin Struct Biol (1996) 1.60
Mouse connexin37: cloning and functional expression of a gap junction gene highly expressed in lung. J Cell Biol (1991) 1.53
A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes. J Cell Sci (1998) 1.53
Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol (1992) 1.49
Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels. J Cell Biol (1999) 1.44
Scaling of F-actin network rheology to probe single filament elasticity and dynamics. Phys Rev Lett (2004) 1.38
Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels. Biophys J (1999) 1.38
Rat liver gap junction protein: properties and partial sequence. Proc Natl Acad Sci U S A (1981) 1.36
Korean Nationwide Surveillance of Antimicrobial Resistance of bacteria in 1997. Yonsei Med J (1998) 1.31
Molecular cloning and functional expression of mouse connexin-30,a gap junction gene highly expressed in adult brain and skin. J Biol Chem (1996) 1.29
Tissue-specific distribution of differentially phosphorylated forms of Cx43. Mol Cell Biol (1991) 1.29
Acute cerebral phaeohyphomycosis due to Wangiella dermatitidis accompanied by cerebrospinal fluid eosinophilia. J Clin Microbiol (2000) 1.19
Direct identification of Vibrio vulnificus in clinical specimens by nested PCR. J Clin Microbiol (1998) 1.18
The dynamic state of liver gap junctions. J Supramol Struct Cell Biochem (1981) 1.18
The cardiac gap junction protein (Mr 47,000) has a tissue-specific cytoplasmic domain of Mr 17,000 at its carboxy-terminus. Biochem Biophys Res Commun (1987) 1.18
The topological structure of connexin 26 and its distribution compared to connexin 32 in hepatic gap junctions. J Membr Biol (1994) 1.17
Comparative analysis of the gap junction protein from rat heart and liver: is there a tissue specificity of gap junctions? Cell (1983) 1.17
The Mr 28,000 gap junction proteins from rat heart and liver are different but related. J Biol Chem (1985) 1.17
Size selectivity between gap junction channels composed of different connexins. Cell Commun Adhes (2001) 1.11
Eugenol protects neuronal cells from excitotoxic and oxidative injury in primary cortical cultures. Neurosci Lett (1997) 1.11
A dual-design expandable colorectal stent for malignant colorectal obstruction: results of a multicenter study. Endoscopy (2007) 1.10
Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin. J Biol Chem (1992) 1.06
Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver. J Cell Sci (1994) 1.04
The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43. Exp Cell Res (1992) 1.04
Usefulness of the carina as a radiographic landmark for central venous catheter placement in paediatric patients. Br J Anaesth (2005) 1.02
Aberrant gating, but a normal expression pattern, underlies the recessive phenotype of the deafness mutant Connexin26M34T. FASEB J (2004) 1.01
Clinical relevance of TNM staging system according to breast cancer subtypes. Ann Oncol (2011) 1.01
Membrane integration of in vitro-translated gap junctional proteins: co- and post-translational mechanisms. Mol Biol Cell (1996) 1.00
Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow. J Bone Joint Surg Br (2001) 0.99
Automated volumetric breast density estimation: a comparison with visual assessment. Clin Radiol (2013) 0.98
Epidemiology of group B streptococcus in Korean pregnant women. Epidemiol Infect (2009) 0.96
Chemistry of gap junctions. Annu Rev Physiol (1985) 0.96
Fluoroscopically guided percutaneous jejunostomy: outcomes in 25 consecutive patients. Clin Radiol (2007) 0.95
Molecular and functional diversity of neural connexins in the retina. J Neurosci (2000) 0.95
Ultrasonography-guided core needle biopsy for the thyroid nodule: does the procedure hold any benefit for the diagnosis when fine-needle aspiration cytology analysis shows inconclusive results? Br J Radiol (2013) 0.94
Molecular organization of gap junctions. Fed Proc (1984) 0.94
Rahnella aquatilis sepsis in an immunocompetent adult. J Clin Microbiol (1999) 0.94
Production and characterization of biologically active human GM-CSF secreted by genetically modified plant cells. Protein Expr Purif (2000) 0.93
Chimerism and mosaicism are important causes of ABO phenotype and genotype discrepancies. Immunohematology (2006) 0.92
Connexin diversity and gap junction regulation by pHi. Dev Genet (1999) 0.92
Connexin trafficking and the control of gap junction assembly in mouse preimplantation embryos. Development (1993) 0.92
Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells. Cancer Res (2000) 0.92
Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen:progesterone ratio. Endocrinology (1993) 0.92
Ultrastructural analysis of gap junctions in C6 glioma cells transfected with connexin43 cDNA. Exp Cell Res (1993) 0.92
Direct isolation and analysis of endogenous transjunctional ADP from Cx43 transfected C6 glioma cells. Exp Cell Res (1998) 0.91
Nonocclusive mesenteric ischemia in a patient on maintenance hemodialysis. Korean J Intern Med (2000) 0.91
Impact of helical computed tomography in clinically evident appendicitis. Emerg Med J (2008) 0.90
Persistent or recurrent varicocoele after failed varicocoelectomy: outcome in patients treated using percutaneous transcatheter embolization. Clin Radiol (2011) 0.89
Applying the Xenopus oocyte expression system to the analysis of gap junction proteins. Methods Mol Biol (2001) 0.89
Hemobilia causing acute biliary pancreatitis after percutaneous liver biopsy. Endoscopy (1999) 0.88
Sentinel lymph node biopsy in papillary thyroid cancer: comparison study of blue dye method and combined radioisotope and blue dye method in papillary thyroid cancer. Eur J Surg Oncol (2009) 0.88
The genetic and phenotypic basis of blood group A subtypes in Koreans. Transfus Med (2005) 0.87
Malignant esophageal-tracheobronchial strictures: parallel placement of covered retrievable expandable nitinol stents. Acta Radiol (2006) 0.87
Sexually dimorphic gene expression in the chick brain before gonadal differentiation. Poult Sci (2009) 0.87
A case of disseminated Nocardia farcinica diagnosed through DNA sequencing in a kidney transplantation patient. Clin Nephrol (2008) 0.87
Activation of the IGF-II gene by HBV-X protein requires PKC and p44/p42 map kinase signalings. Biochem Biophys Res Commun (2001) 0.86
Hemocompatibility of surface-modified, silicon-incorporated, diamond-like carbon films. Acta Biomater (2008) 0.86
Molecular typing of Vibrio vulnificus isolates by random amplified polymorphic DNA (RAPD) analysis. Jpn J Med Sci Biol (1997) 0.85
Analysis of the gene encoding cyclomaltodextrinase from alkalophilic Bacillus sp. I-5 and characterization of enzymatic properties. Arch Biochem Biophys (1998) 0.85
Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters. Cancer Res (1994) 0.85
Deep tracheal laceration after balloon dilation for benign tracheobronchial stenosis: case reports of two patients. Br J Radiol (2006) 0.85
Multiplex in-cell reverse transcription-polymerase chain reaction for the simultaneous detection of p210 and p190 BCR-ABL mRNAs in chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia cell lines. Clin Chem Lab Med (2000) 0.85
Gap junctions in liver: isolation, morphological analysis, and quantitation. Methods Enzymol (1983) 0.85
Retinoid-enhanced gap junctional communication is achieved by increased levels of connexin 43 mRNA and protein. Mol Carcinog (1990) 0.85
Primary cutaneous mucormycosis in a trauma patient. J Dermatol (1999) 0.84
Proliferation-associated differences in the spatial and temporal expression of gap junction genes in rat liver. Hepatology (1995) 0.84
Association of the CD14 gene -159C polymorphism with progression of IgA nephropathy. J Med Genet (2003) 0.84
A novel B(var) allele (547 G>A) demonstrates differential expression depending on the co-inherited ABO allele. Vox Sang (2004) 0.84
Renal perfusion abnormality. Coded harmonic angio US with contrast agent. Acta Radiol (2003) 0.83
The axillopectoral muscle seen on mammography. Clin Radiol (2006) 0.83
Changes in the evolution of the antigenic profiles and morphology during coccoid conversion of Helicobacter pylori. Korean J Intern Med (1999) 0.82
ACE gene polymorphism and renal responsiveness to ACE inhibitors in IgA nephropathy patients. Korean J Intern Med (2000) 0.82
Primary anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma of the breast in a male patient. Br J Radiol (2012) 0.82
Cerebral morphometry and clozapine treatment in schizophrenia. J Clin Psychiatry (1994) 0.82
Major intrinsic polypeptide of lens membrane. Biochemical and immunological characterization of the major cyanogen bromide fragment. Biochim Biophys Acta (1983) 0.82
A preliminary report of the virtual craniofacial center: development of Internet-/Intranet-based care coordination of pediatric craniofacial patients. Ann Plast Surg (2001) 0.81
Differences in the expression of connexin genes in rat hepatomas in vivo and in vitro. Mol Carcinog (1994) 0.81
Supratentorial gangliocytoma mimicking extra-axial tumor: a report of two cases. Korean J Radiol (2001) 0.81
Purification of the lysosomal acid lipase from human liver and its role in lysosomal lipid hydrolysis. J Biol Chem (1981) 0.81
Molecular typing of vibrio vulnificus isolated from clinical specimens by pulsed-field gel electrophoresis and random amplified polymorphic DNA analysis. Jpn J Infect Dis (1999) 0.81
Oesophageal strictures caused by the ingestion of corrosive agents: effectiveness of balloon dilatation in children. Clin Radiol (2008) 0.81
Lymphonodular cryptococcosis diagnosed by fine needle aspiration cytology in hyper-IgM syndrome. A case report. Acta Cytol (2001) 0.81
Induction of mononuclear precursor cells with osteoclastic phenotypes in a rat bone marrow culture system depleted of stromal cells. Biochem Biophys Res Commun (1993) 0.81
Spitz naevus is rare in Korea. Clin Exp Dermatol (2009) 0.80
Identification and characterization of the peroxiredoxin gene family in chickens. Poult Sci (2005) 0.80
Partial sequence and turnover of rat liver gap junction protein. Cold Spring Harb Symp Quant Biol (1982) 0.80
Synthesis of the quinoline-linked triazolopyrimidine analogues and their interactions with the recombinant tobacco acetolactate synthase. Biochem Biophys Res Commun (1999) 0.79