Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations.

PubWeight™: 1.40‹?› | Rank: Top 5%

🔗 View Article (PMID 12406872)

Published in Blood on October 24, 2002

Authors

Jose A Martinez-Climent1, Ash A Alizadeh, Richard Segraves, David Blesa, Fanny Rubio-Moscardo, Donna G Albertson, Javier Garcia-Conde, Martin J S Dyer, Ronald Levy, Daniel Pinkel, Izidore S Lossos

Author Affiliations

1: Department of Hematology and Medical Oncology, Hospital Clinico, University of Valencia, Spain. martinez_jos@gva.es

Articles citing this

A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients. Blood (2009) 1.74

Genetics of follicular lymphoma transformation. Cell Rep (2014) 1.70

Role of the chromobox protein CBX7 in lymphomagenesis. Proc Natl Acad Sci U S A (2007) 1.65

Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha. Leuk Lymphoma (2010) 1.46

Chromosome 6p amplification and cancer progression. J Clin Pathol (2006) 1.42

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations. Proc Natl Acad Sci U S A (2004) 1.40

Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms. Br J Haematol (2007) 1.28

Transformation of follicular lymphoma. Best Pract Res Clin Haematol (2011) 1.27

A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH. BMC Genomics (2007) 1.17

The c-Rel Transcription Factor in Development and Disease. Genes Cancer (2011) 1.01

Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma. Proc Natl Acad Sci U S A (2004) 0.94

Tanzanian malignant lymphomas: WHO classification, presentation, ploidy, proliferation and HIV/EBV association. BMC Cancer (2010) 0.92

Treatment options for transformed lymphoma: incorporating allogeneic stem cell transplantation in a multimodality approach. Biol Blood Marrow Transplant (2011) 0.92

Molecular cytogenetics in haematological malignancy: current technology and future prospects. Chromosoma (2005) 0.92

The progress on genetic analysis of nasopharyngeal carcinoma. Comp Funct Genomics (2007) 0.91

PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal. Stem Cells (2014) 0.90

Lymphoma stem cells: enough evidence to support their existence? Haematologica (2010) 0.90

Genetic lesions in diffuse large B-cell lymphomas. Ann Oncol (2015) 0.89

Amplification of 2p as a genomic marker for transformation in lymphoma. Genes Chromosomes Cancer (2014) 0.83

PRL-2 increases Epo and IL-3 responses in hematopoietic cells. Blood Cells Mol Dis (2010) 0.82

Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21). Leukemia (2011) 0.82

Molecular characterization of the region 7q22.1 in splenic marginal zone lymphomas. PLoS One (2011) 0.81

SNPs Array Karyotyping in Non-Hodgkin Lymphoma. Microarrays (Basel) (2015) 0.81

SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets. BMC Bioinformatics (2007) 0.80

Functional genomics lead to new therapies in follicular lymphoma. Ann N Y Acad Sci (2013) 0.79

Phosphatase of regenerating liver in hematopoietic stem cells and hematological malignancies. Cell Cycle (2014) 0.78

Progress against follicular lymphoma. Curr Opin Hematol (2013) 0.76

Microarray and its applications. J Pharm Bioallied Sci (2012) 0.76

Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers. Am J Transl Res (2016) 0.75

The Role of c-MYC in B-Cell Lymphomas: Diagnostic and Molecular Aspects. Genes (Basel) (2017) 0.75

Complex Chromosomal Rearrangements in B-Cell Lymphoma: Evidence of Chromoanagenesis? A Case Report. Neoplasia (2016) 0.75

Altered expression of the PMAIP1 gene: A major player in the evolution of gastrointestinal and systemic malignancies. Dig Dis Sci (2008) 0.75

Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission. Exp Hematol Oncol (2017) 0.75

PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity. Mol Cell (2016) 0.75

Follicular lymphoma transforming into anaplastic diffuse large B-cell lymphoma of oral cavity: A case report with review of literature. J Oral Maxillofac Pathol (2016) 0.75

Whole-exome and transcriptome sequencing of refractory diffuse large B-cell lymphoma. Oncotarget (2016) 0.75

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors. Stem Cells (2017) 0.75

Articles by these authors

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell (2006) 27.36

Fine-scale structural variation of the human genome. Nat Genet (2005) 24.31

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell (2006) 16.05

Segmental duplications and copy-number variation in the human genome. Am J Hum Genet (2005) 13.33

Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome. Nat Genet (2006) 10.36

SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. Nucleic Acids Res (2003) 10.28

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol (2004) 9.38

Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol (2006) 7.76

Linkage disequilibrium and heritability of copy-number polymorphisms within duplicated regions of the human genome. Am J Hum Genet (2006) 7.70

A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet (2004) 7.68

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature (2005) 7.24

Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. N Engl J Med (2004) 6.91

Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol (2003) 6.77

Array comparative genomic hybridization and its applications in cancer. Nat Genet (2005) 6.69

Individuality and variation in gene expression patterns in human blood. Proc Natl Acad Sci U S A (2003) 6.49

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood (2009) 5.84

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30

Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol (2010) 4.79

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet (2008) 4.37

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A (2012) 4.20

Genomic microarrays in human genetic disease and cancer. Hum Mol Genet (2003) 4.15

Whole genome analysis of genetic alterations in small DNA samples using hyperbranched strand displacement amplification and array-CGH. Genome Res (2003) 4.10

In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I/II study. J Clin Oncol (2010) 3.88

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia. Blood (2008) 3.85

Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proc Natl Acad Sci U S A (2002) 3.85

The connectome of a decision-making neural network. Science (2012) 3.70

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. Blood (2010) 3.69

Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst (2003) 3.65

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood (2009) 3.50

Fully automatic quantification of microarray image data. Genome Res (2002) 3.47

Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell (2010) 3.37

Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer (2006) 3.34

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci U S A (2002) 3.28

Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics (2006) 3.27

Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA (2010) 3.25

Structural organization of bacterial RNA polymerase holoenzyme and the RNA polymerase-promoter open complex. Cell (2002) 3.21

Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues. Arthritis Rheum (2003) 3.05

Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene (2005) 2.99

MC1R germline variants confer risk for BRAF-mutant melanoma. Science (2006) 2.84

Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma. J Clin Oncol (2008) 2.80

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci Transl Med (2010) 2.79

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. J Clin Invest (2013) 2.77

BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation. Blood (2011) 2.68

Extranodal marginal zone lymphoma of the ocular adnexa. Blood (2009) 2.65

Improving melanoma classification by integrating genetic and morphologic features. PLoS Med (2008) 2.52

Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients. Blood (2002) 2.52

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nat Genet (2005) 2.51

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nat Genet (2010) 2.45

Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization. Genome Res (2003) 2.41

Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood (2008) 2.36

Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer Res (2003) 2.34

Comparative genomic hybridization. Annu Rev Genomics Hum Genet (2005) 2.34

Regional copy number-independent deregulation of transcription in cancer. Nat Genet (2006) 2.33

Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood (2006) 2.32

Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res (2010) 2.25

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival. Blood (2009) 2.22

Oral and extraoral plasmablastic lymphoma: similarities and differences in clinicopathologic characteristics. Am J Clin Pathol (2010) 2.10

B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc Natl Acad Sci U S A (2010) 2.10

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood (2006) 2.10

Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma. Br J Haematol (2009) 2.09

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Blood (2010) 2.09

CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. Blood (2010) 2.06

A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation. PLoS One (2006) 2.05

Classifying melanocytic tumors based on DNA copy number changes. Am J Pathol (2003) 2.05

In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a phase 1/2 study. Blood (2011) 2.02

Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. Blood (2005) 1.99

Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res (2002) 1.96

The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Blood (2006) 1.94

Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. J Clin Invest (2012) 1.92

LMO2 protein expression predicts survival in patients with diffuse large B-cell lymphoma treated with anthracycline-based chemotherapy with and without rituximab. J Clin Oncol (2007) 1.88

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood (2013) 1.86

Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. Blood (2010) 1.86