Published in Br Med Bull on January 01, 2002
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc Natl Acad Sci U S A (2004) 3.95
Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin. Proc Natl Acad Sci U S A (2012) 1.98
Cancer genetics: colorectal cancer as a model. J Hum Genet (2006) 1.64
Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer. World J Gastroenterol (2006) 1.52
Genetic alteration and gene expression modulation during cancer progression. Mol Cancer (2004) 1.50
Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression. Cancer Epidemiol Biomarkers Prev (2009) 1.43
Integrated analysis of germline and somatic variants in ovarian cancer. Nat Commun (2014) 1.31
APC and its modifiers in colon cancer. Adv Exp Med Biol (2009) 1.28
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Med (2010) 1.26
Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. BMC Cancer (2011) 1.19
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair. Cancer Lett (2008) 0.99
Spontaneous immortalization of clinically normal colon-derived fibroblasts from a familial adenomatous polyposis patient. Neoplasia (2004) 0.93
Low-serum GTA-446 anti-inflammatory fatty acid levels as a new risk factor for colon cancer. Int J Cancer (2012) 0.91
Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study. BMJ Open (2015) 0.91
Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila) (2013) 0.90
The in vivo rate of somatic adenomatous polyposis coli mutation. Am J Pathol (2008) 0.88
Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients. Int J Colorectal Dis (2007) 0.86
Targeting mTOR network in colorectal cancer therapy. World J Gastroenterol (2014) 0.86
Single nucleotide polymorphisms in microRNA binding sites: implications in colorectal cancer. ScientificWorldJournal (2014) 0.85
A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family history. Fam Cancer (2005) 0.85
Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer. J Hum Genet (2012) 0.83
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer. PLoS One (2011) 0.81
Genetic mutations in human rectal cancers detected by targeted sequencing. J Hum Genet (2015) 0.80
Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis. Life Sci (2015) 0.77
Microsatellite instability and loss of heterozygosity detected in middle-aged patients with sporadic colon cancer: A retrospective study. Oncol Lett (2013) 0.76
The association between DNA copy number aberrations at chromosome 5q22 and gastric cancer. PLoS One (2014) 0.76
Embryonic reversions and lineage infidelities in tumour cells: genome-based models and role of genetic instability. Int J Exp Pathol (2005) 0.75
Immunopurification of adenomatous polyposis coli (APC) proteins. BMC Res Notes (2013) 0.75
A Rare Case of FAP in Kashmir Valley. Indian J Surg (2011) 0.75
H19 Overexpression Induces Resistance to 1,25(OH)2D3 by Targeting VDR Through miR-675-5p in Colon Cancer Cells. Neoplasia (2017) 0.75
Results from a retrospective analysis of colonoscopies for Inflammatory bowel disease and colorectal cancer in a Lebanese tertiary care centre. BMJ Open Gastroenterol (2017) 0.75
Overexpression of long non-coding RNA H19 is associated with unfavorable prognosis in patients with colorectal cancer and increased proliferation and migration in colon cancer cells. Oncol Lett (2017) 0.75
A human genome diversity cell line panel. Science (2002) 14.11
Multigene amplification and massively parallel sequencing for cancer mutation discovery. Proc Natl Acad Sci U S A (2007) 3.93
Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci U S A (2004) 3.62
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Cancer Res (2003) 2.24
Cancer stem cells from colorectal cancer-derived cell lines. Proc Natl Acad Sci U S A (2010) 2.22
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines. Proc Natl Acad Sci U S A (2006) 2.18
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer. Proc Natl Acad Sci U S A (2007) 1.99
Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model. Cell Cycle (2005) 1.92
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proc Natl Acad Sci U S A (2003) 1.79
Cancer cell lines for drug discovery and development. Cancer Res (2014) 1.60
Mutations in the AXIN1 gene in advanced prostate cancer. Eur Urol (2008) 1.53
Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1. Proc Natl Acad Sci U S A (2009) 1.20
Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition. Proc Natl Acad Sci U S A (2010) 1.16
Nomenclature for Factors of the HLA System, 2004. Hum Immunol (2005) 1.14
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci U S A (2008) 1.13
Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells. Proc Natl Acad Sci U S A (2011) 1.11
Examples of mathematical modeling: tales from the crypt. Cell Cycle (2007) 1.11
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. Am J Pathol (2003) 1.08
Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe. Eur J Hum Genet (2010) 1.06
Genotyping possible polymorphic variants of human mismatch repair genes in healthy Korean individuals and sporadic colorectal cancer patients. Fam Cancer (2004) 0.99
On the proportion of cancer stem cells in a tumour. J Theor Biol (2010) 0.97
MSI-low, a real phenomenon which varies in frequency among cancer types. J Pathol (2003) 0.91
Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel. Proc Natl Acad Sci U S A (2012) 0.90
Nomenclature for factors of the HLA system, 2002. Hum Immunol (2002) 0.88
Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors. Cancer Res (2013) 0.87
Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients. J Hum Genet (2010) 0.82
Nomenclature for factors of the HLA system, 2002. Eur J Immunogenet (2002) 0.81
Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays. J Pathol (2014) 0.79
Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery. Int J Cancer (2002) 0.78
Commentary: Connections between genetics and statistics: a commentary on Fisher's 1951 Bateson lecture--'Statistical Methods in Genetics'. Int J Epidemiol (2010) 0.77
Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions. Proc Natl Acad Sci U S A (2010) 0.76