Tourette's syndrome.

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🔗 View Article (PMID 12443611)

Published in Lancet on November 16, 2002

Authors

James F Leckman1

Author Affiliations

1: Child Study Center and Departments of Paediatrics, Psychiatry, and Psychology, Yale University, New Haven, CT 06520-7900, USA. James.Leckman@yale.edu

Associated clinical trials:

Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome (TMS) | NCT00529308

Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI | NCT05232955

Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 2: 7T MRI | NCT05233306

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Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol (2010) 1.89

Co-existing disorders in ADHD -- implications for diagnosis and intervention. Eur Child Adolesc Psychiatry (2004) 1.88

European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. Eur Child Adolesc Psychiatry (2011) 1.86

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Clinical course of Tourette syndrome. J Psychosom Res (2009) 1.74

Increased GABA contributes to enhanced control over motor excitability in Tourette syndrome. Curr Biol (2014) 1.67

Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proc Natl Acad Sci U S A (2015) 1.59

Annual research review: The neurobehavioral development of multiple memory systems--implications for childhood and adolescent psychiatric disorders. J Child Psychol Psychiatry (2013) 1.46

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Neurobiological substrates of Tourette's disorder. J Child Adolesc Psychopharmacol (2010) 1.27

Meta-analysis: treatment of attention-deficit/hyperactivity disorder in children with comorbid tic disorders. J Am Acad Child Adolesc Psychiatry (2009) 1.26

Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive-compulsive disorder. J Child Psychol Psychiatry (2007) 1.23

Immunopathogenic mechanisms in tourette syndrome: A critical review. Mov Disord (2009) 1.16

Imaging evidence for anatomical disturbances and neuroplastic compensation in persons with Tourette syndrome. J Psychosom Res (2009) 1.16

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Compensatory neural reorganization in Tourette syndrome. Curr Biol (2011) 1.11

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Slitrks as emerging candidate genes involved in neuropsychiatric disorders. Trends Neurosci (2011) 1.04

Transcriptome Analysis of the Human Striatum in Tourette Syndrome. Biol Psychiatry (2014) 1.02

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Biofeedback of real-time functional magnetic resonance imaging data from the supplementary motor area reduces functional connectivity to subcortical regions. Brain Connect (2011) 0.99

Increased thalamic gamma band activity correlates with symptom relief following deep brain stimulation in humans with Tourette's syndrome. PLoS One (2012) 0.99

Indications of linkage and association of Gilles de la Tourette syndrome in two independent family samples: 17q25 is a putative susceptibility region. Am J Hum Genet (2004) 0.98

Comparison of clinical features among youth with tic disorders, obsessive-compulsive disorder (OCD), and both conditions. Psychiatry Res (2010) 0.95

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Imaging the where and when of tic generation and resting state networks in adult Tourette patients. Front Hum Neurosci (2014) 0.91

Identification of pyruvate kinase as an antigen associated with Tourette syndrome. J Neuroimmunol (2006) 0.91

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Deep brain stimulation in tourette syndrome: a description of 3 patients with excellent outcome. Mayo Clin Proc (2012) 0.90

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Open-label study comparing the efficacy and tolerability of aripiprazole and haloperidol in the treatment of pediatric tic disorders. Eur Child Adolesc Psychiatry (2010) 0.89

Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear. Neurosci Lett (2015) 0.88

A cluster analysis of tic symptoms in children and adults with Tourette syndrome: clinical correlates and treatment outcome. Psychiatry Res (2013) 0.88

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Exon expression and alternatively spliced genes in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet (2010) 0.87

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Neuroimaging of tic disorders with co-existing attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry (2007) 0.84

High levels of histidine decarboxylase in the striatum of mice and rats. Neurosci Lett (2011) 0.84

Ablation of fast-spiking interneurons in the dorsal striatum, recapitulating abnormalities seen post-mortem in Tourette syndrome, produces anxiety and elevated grooming. Neuroscience (2016) 0.83

Altered immunoglobulin profiles in children with Tourette syndrome. Brain Behav Immun (2010) 0.83

Tourette syndrome and obsessive-compulsive disorder. Brain Dev (2007) 0.83

Motor excitability is reduced prior to voluntary movements in children and adolescents with Tourette syndrome. J Neuropsychol (2012) 0.83

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The Prevalence of Tic Disorders and Clinical Characteristics in Children. J Obsessive Compuls Relat Disord (2014) 0.82

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Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome. Neurology (2009) 0.80

Functional brain asymmetry, attentional modulation, and interhemispheric transfer in boys with Tourette syndrome. Neuropsychologia (2006) 0.80

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Air swallowing caused recurrent ileus in Tourette's syndrome. Pediatrics (2006) 0.78

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Involvement of immunologic and biochemical mechanisms in the pathogenesis of Tourette's syndrome. J Neural Transm (Vienna) (2011) 0.76

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The Use of Deep Brain Stimulation in Tourette Syndrome. Brain Sci (2016) 0.76

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Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations. PLoS One (2017) 0.75

Beck Depression Inventory is a useful screening tool for major depressive disorder in Gilles de la Tourette syndrome. J Neurol Neurosurg Psychiatry (2006) 0.75

Tic Frequency Decreases during Short-term Psychosocial Stress - An Experimental Study on Children with Tic Disorders. Front Psychiatry (2016) 0.75

Dual ameliorative effects of Ningdong granule on dopamine in rat models of Tourette's syndrome. Sci Rep (2015) 0.75

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Association between Tourette syndrome and the dopamine D3 receptor gene rs6280. Chin Med J (Engl) (2015) 0.75

Neurosurgical strategies for Gilles de la Tourette's syndrome. Neuropsychiatr Dis Treat (2008) 0.75

Tourette-like behaviors in the normal population are associated with hyperactive/impulsive ADHD-like behaviors but do not relate to deficits in conditioned inhibition or response inhibition. Front Psychol (2014) 0.75

Sources of Disability in Tourette Syndrome: Children vs. Adults. Tremor Other Hyperkinet Mov (N Y) (2016) 0.75

Deep Brain Stimulation for Tourette's Syndrome: The Case for Targeting the Thalamic Centromedian-Parafascicular Complex. Front Neurol (2016) 0.75

Performance Monitoring in Medication-Naïve Children with Tourette Syndrome. Front Neurosci (2016) 0.75