Published in Endocrinology on December 01, 2002
Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Natl Acad Sci U S A (2004) 7.96
Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis. Genes Dev (2009) 4.29
Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci (2003) 3.52
Hormonal and local control of mammary branching morphogenesis. Differentiation (2006) 2.60
Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland. Breast Cancer Res (2012) 2.18
Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man? Breast Cancer Res (2007) 1.57
Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist. Mol Cell Endocrinol (2007) 1.30
Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice. Proc Natl Acad Sci U S A (2009) 1.23
New highlights on stroma-epithelial interactions in breast cancer. Breast Cancer Res (2004) 1.19
Models of breast cancer: quo vadis, animal modeling? Breast Cancer Res (2003) 1.10
The ADAM17-amphiregulin-EGFR axis in mammary development and cancer. J Mammary Gland Biol Neoplasia (2008) 1.06
Quantitation of human mammary epithelial stem cells with in vivo regenerative properties using a subrenal capsule xenotransplantation assay. Nat Protoc (2010) 0.91
Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia (2007) 0.88
Estrogen receptor β potentiates the antiproliferative effect of raloxifene and affects the cell migration and invasion in HCT-116 colon cancer cells. J Cancer Res Clin Oncol (2012) 0.85
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation. Breast Cancer Res (2015) 0.81
ERrrr…Where are the Progenitors? Hormone Receptors and Mammary Cell Heterogeneity. J Mammary Gland Biol Neoplasia (2015) 0.79
Role of CEACAM1, ECM, and mesenchymal stem cells in an orthotopic model of human breast cancer. Int J Breast Cancer (2010) 0.79
Development of Foreign Mammary Epithelial Morphology in the Stroma of Immunodeficient Mice. PLoS One (2013) 0.78
Stromal fibroblasts influence human mammary epithelial cell morphogenesis. Proc Natl Acad Sci U S A (2004) 0.78
Establishment of human patient-derived endometrial cancer xenografts in NOD scid gamma mice for the study of invasion and metastasis. PLoS One (2014) 0.77
Therapeutic effect of the treatment for colorectal cancer with adenoviral vectors mediated estrogen receptor β gene therapy combined with thermotherapy. J Cancer Res Clin Oncol (2014) 0.77
Hormone-responsive 3D multicellular culture model of human breast tissue. Biomaterials (2012) 0.76
Breast cancer clinical and translational research: analogies and implications for prostate cancer. Rev Urol (2007) 0.75
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell (2006) 16.05
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res (2008) 8.12
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol (2007) 5.81
Subtype and pathway specific responses to anticancer compounds in breast cancer. Proc Natl Acad Sci U S A (2011) 4.55
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Restriction of receptor movement alters cellular response: physical force sensing by EphA2. Science (2010) 3.72
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med (2008) 3.64
Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer (2006) 3.34
A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers. Clin Proteomics (2010) 3.25
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res (2009) 3.14
Hormonal, cellular, and molecular control of prostatic development. Dev Biol (2003) 2.67
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res (2004) 2.67
Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling. FASEB J (2007) 2.40
Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.38
Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res (2002) 2.29
A conditional feedback loop regulates Ras activity through EphA2. Cancer Cell (2005) 2.27
Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer. Am J Pathol (2007) 2.23
Role of p63 and basal cells in the prostate. Development (2004) 2.00
Epithelial progenitors in the normal human mammary gland. J Mammary Gland Biol Neoplasia (2005) 1.74
Mutations in SEPT9 cause hereditary neuralgic amyotrophy. Nat Genet (2005) 1.68
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA. Cancer Res (2004) 1.66
Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice. Cancer Cell (2007) 1.59
Mouse urogenital development: a practical approach. Differentiation (2003) 1.59
Epithelial-stromal interactions in the mouse and human mammary gland in vivo. Endocr Relat Cancer (2004) 1.57
Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer. Cancer Res (2005) 1.56
Differential expression of p63 isoforms in female reproductive organs. Mech Dev (2005) 1.55
FGF-10 plays an essential role in the growth of the fetal prostate. Dev Biol (2003) 1.53
Formation of human prostate tissue from embryonic stem cells. Nat Methods (2006) 1.50
Development and characterization of efficient xenograft models for benign and malignant human prostate tissue. Prostate (2005) 1.49
Sleep disorders in Charcot-Marie-Tooth disease type 1. J Neurol Neurosurg Psychiatry (2013) 1.47
Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Res (2012) 1.47
Chlorhexidine to maintain cleanliness of laryngoscope handles: an audit and laboratory study. Eur J Anaesthesiol (2013) 1.46
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer. Clin Cancer Res (2009) 1.43
Cellular and molecular mechanisms of development of the external genitalia. Differentiation (2003) 1.41
Stem/progenitor and intermediate cell types and the origin of human prostate cancer. Differentiation (2005) 1.40
Report of a novel mutation in the PMP22 gene causing an axonal neuropathy. Muscle Nerve (2011) 1.40
Sonic hedgehog regulates prostatic growth and epithelial differentiation. Dev Biol (2003) 1.32
Steroid hormones stimulate human prostate cancer progression and metastasis. Int J Cancer (2006) 1.32
Unraveling the biologic and clinical complexities of HER2. Clin Breast Cancer (2008) 1.32
Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival. Cancer Res (2006) 1.31
Induction of hypospadias in a murine model by maternal exposure to synthetic estrogens. Environ Res (2004) 1.30
Expression profiling of the mouse prostate after castration and hormone replacement: implication of H-cadherin in prostate tumorigenesis. Differentiation (2006) 1.29
Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis. Development (2004) 1.26
Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells. Stem Cells (2012) 1.25
MUC1 mediates transendothelial migration in vitro by ligating endothelial cell ICAM-1. Clin Exp Metastasis (2005) 1.23
Morphology of mouse external genitalia: implications for a role of estrogen in sexual dimorphism of the mouse genital tubercle. J Urol (2010) 1.23
New insights on the morphology of adult mouse penis. Biol Reprod (2011) 1.22
A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med (2009) 1.22
Expression of the androgen receptor and 5 alpha-reductase type 2 in the developing human fetal penis and urethra. Cell Tissue Res (2001) 1.21
An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Lab Invest (2005) 1.19
Molecular cell biology of Charcot-Marie-Tooth disease. Neurogenetics (2002) 1.17
Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. Prostate (2007) 1.14
The protooncogene Ski controls Schwann cell proliferation and myelination. Neuron (2004) 1.13
Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity. Methods Mol Biol (2005) 1.12
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. Neurogenetics (2009) 1.10
Molecular, cellular and developmental biology of urothelium as a basis of bladder regeneration. Differentiation (2005) 1.09
Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast. Breast Cancer Res Treat (2008) 1.07
Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression. Proc Natl Acad Sci U S A (2002) 1.07
Steroid hormones and carcinogenesis of the prostate: the role of estrogens. Differentiation (2007) 1.06
An animal model for Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet (2005) 1.06
Treatment for obstructive sleep apnoea: effect on peripheral nerve function. J Neurol Neurosurg Psychiatry (2006) 1.05
The role of smooth muscle in regulating prostatic induction. Development (2002) 1.03
A fluid membrane-based soluble ligand-display system for live-cell assays. Chembiochem (2006) 1.03
Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis. Carcinogenesis (2012) 1.03
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2. Hum Mol Genet (2007) 1.02
Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoter. Proc Natl Acad Sci U S A (2001) 1.02
Atherosclerosis and obstructive sleep apnea in patients with ischemic stroke. Cerebrovasc Dis (2007) 0.99
Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation. Glia (2006) 0.99
Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. Transcription (2012) 0.99
Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology. BMC Bioinformatics (2012) 0.98
Role of systemic and local IGF-I in the effects of estrogen on growth and epithelial proliferation of mouse uterus. Endocrinology (2002) 0.95
Mammalian sexual differentiation: lessons from the spotted hyena. Trends Endocrinol Metab (2006) 0.95
Fatigue, reduced sleep quality and restless legs syndrome in Charcot-Marie-Tooth disease: a web-based survey. J Neurol (2009) 0.95
Analysis of the effect of estrogen/androgen perturbation on penile development in transgenic and diethylstilbestrol-treated mice. Anat Rec (Hoboken) (2013) 0.95
Intensive care unit tracheostomy: a snapshot of UK practice. Int Arch Med (2008) 0.95
Inhibition of N-cadherin and beta-catenin function reduces axon-induced Schwann cell proliferation. J Neurosci Res (2008) 0.95
Charcot-Marie-Tooth disease: frequency of genetic subtypes in a German neuromuscular center population. Neuromuscul Disord (2013) 0.94
Positional sleep apnea in patients with ischemic stroke. Neurol Res (2008) 0.94
Molecular mechanisms of external genitalia development. Differentiation (2012) 0.94
The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo. Mol Cancer Ther (2007) 0.93
A tighter bound for the echo state property. IEEE Trans Neural Netw (2006) 0.93
Sparse combinatorial inference with an application in cancer biology. Bioinformatics (2008) 0.93
Quantitation of apoptotic activity following castration in human prostatic tissue in vivo. Prostate (2003) 0.92
Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer. Cell Cycle (2006) 0.92
The activation function-1 domain of estrogen receptor alpha in uterine stromal cells is required for mouse but not human uterine epithelial response to estrogen. Differentiation (2005) 0.92
Capnography screening for sleep apnea in patients with acute stroke. Neurol Res (2005) 0.92
Early microstructural white matter changes in patients with HIV: a diffusion tensor imaging study. BMC Neurol (2012) 0.91
Steroid receptors and mammalian penile development: an unexpected role for progesterone receptor? J Urol (2006) 0.91
Lineage enforcement by inductive mesenchyme on adult epithelial stem cells across developmental germ layers. Stem Cells (2009) 0.91
Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer. Differentiation (2008) 0.91
Stress-induced allodynia--evidence of increased pain sensitivity in healthy humans and patients with chronic pain after experimentally induced psychosocial stress. PLoS One (2013) 0.90
Continuous positive airway pressure ventilation for acute ischemic stroke: a randomized feasibility study. Stroke (2011) 0.90
Signalling molecules involved in mouse bladder smooth muscle cellular differentiation. Int J Dev Biol (2010) 0.89
A case of triploidy. Fertil Steril (2005) 0.89
Clinical features and molecular genetics of hereditary peripheral neuropathies. J Neurol (2002) 0.88
Phenotype and frequency of STUB1 mutations: next-generation screenings in Caucasian ataxia and spastic paraplegia cohorts. Orphanet J Rare Dis (2014) 0.88
The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. J Neurochem (2010) 0.87