David M Stern

Author PubWeight™ 96.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Understanding RAGE, the receptor for advanced glycation end products. J Mol Med (Berl) 2005 4.96
2 Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest 2004 4.04
3 RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice. Circulation 2002 3.93
4 Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response. J Clin Invest 2004 3.89
5 Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nat Med 2012 3.31
6 The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest 2005 2.80
7 RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am J Pathol 2003 2.43
8 Central role of RAGE-dependent neointimal expansion in arterial restenosis. J Clin Invest 2003 2.40
9 Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses. Circulation 2002 2.18
10 RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J 2004 2.08
11 Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J Clin Invest 2004 1.92
12 ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. FASEB J 2005 1.89
13 RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci U S A 2009 1.74
14 Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J Neurosci 2008 1.67
15 Circulating CD34-positive cells provide an index of cerebrovascular function. Circulation 2004 1.66
16 Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system. Nat Med 2003 1.62
17 Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction. Stem Cells 2009 1.42
18 RAGE in inflammation: a new therapeutic target? Curr Opin Investig Drugs 2006 1.40
19 RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J 2009 1.39
20 Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury. Circulation 2003 1.38
21 Role of the JAK/STAT signaling pathway in diabetic nephropathy. Am J Physiol Renal Physiol 2006 1.34
22 RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation? J Alzheimers Dis 2009 1.31
23 Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes. Curr Atheroscler Rep 2002 1.30
24 Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation. Circ Res 2003 1.27
25 RAGE-mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs). J Leukoc Biol 2002 1.25
26 Regulation of osteoclast function and bone mass by RAGE. J Exp Med 2006 1.21
27 Role of Herp in the endoplasmic reticulum stress response. Genes Cells 2004 1.19
28 Chronic vascular inflammation in patients with type 2 diabetes: endothelial biopsy and RT-PCR analysis. Diabetes Care 2005 1.19
29 Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice. Diabetes 2008 1.17
30 Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD). Int J Exp Pathol 2005 1.17
31 Posttranslationally modified proteins as mediators of sustained intestinal inflammation. Am J Pathol 2006 1.13
32 Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders. Arch Biochem Biophys 2003 1.12
33 Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss. Biochem Biophys Res Commun 2005 1.11
34 Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease. J Neurosci 2011 1.11
35 ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death. FASEB J 2004 1.11
36 Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice. Eur J Neurosci 2009 1.07
37 Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet 2006 1.06
38 Injury-induced neural stem/progenitor cells in post-stroke human cerebral cortex. Eur J Neurosci 2010 1.05
39 S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular smooth muscle cells is dependent on PLD2. Diabetes 2003 1.04
40 Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. Am J Physiol Renal Physiol 2006 1.03
41 Receptor for advanced glycation end products on human synovial fibroblasts: role in the pathogenesis of dialysis-related amyloidosis. J Am Soc Nephrol 2002 1.03
42 Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Mol Cell Biol 2006 1.01
43 Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease. J Pharmacol Sci 2005 1.01
44 L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease. Ann Neurol 2004 1.01
45 Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke. J Neurosci Res 2010 0.98
46 PKCbeta regulates ischemia/reperfusion injury in the lung. J Clin Invest 2004 0.98
47 Advanced glycation end product receptor-mediated cellular dysfunction. Ann N Y Acad Sci 2005 0.97
48 Tissue factor as a link between wounding and tissue repair. Diabetes 2005 0.97
49 ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. J Neurosci 2004 0.95
50 Granulocyte colony-stimulating factor has a negative effect on stroke outcome in a murine model. Eur J Neurosci 2007 0.94
51 Circulating CD34-positive cells have prognostic value for neurologic function in patients with past cerebral infarction. J Cereb Blood Flow Metab 2008 0.89
52 Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2. Vascul Pharmacol 2005 0.88
53 Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia. Brain Res 2010 0.88
54 Increase in circulating CD34-positive cells in patients with angiographic evidence of moyamoya-like vessels. J Cereb Blood Flow Metab 2008 0.87
55 Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats. J Cereb Blood Flow Metab 2010 0.86
56 Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: a pilot study. Brain Res Bull 2007 0.86
57 Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection. Mol Cell Biochem 2009 0.85
58 Angiotensin II-induced insulin resistance and protein tyrosine phosphatases. Arterioscler Thromb Vasc Biol 2004 0.85
59 A Reproducible and Simple Model of Permanent Cerebral Ischemia in CB-17 and SCID Mice. J Exp Stroke Transl Med 2010 0.84
60 Circulating CD34-positive cells provide a marker of vascular risk associated with cognitive impairment. J Cereb Blood Flow Metab 2007 0.84
61 RAGE and its ligands: a lasting memory in diabetic complications? Diab Vasc Dis Res 2004 0.84
62 A new protocol for quantifying CD34(+) cells in peripheral blood of patients with cardiovascular disease. Tex Heart Inst J 2006 0.83
63 Angiotensin II-induced signaling pathways in diabetes. Curr Diabetes Rev 2005 0.82
64 Atherosclerosis and restenosis: is there a role for RAGE? Curr Diab Rep 2005 0.82
65 Mitochondrial amyloid-beta peptide: pathogenesis or late-phase development? J Alzheimers Dis 2006 0.81
66 CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity. J Immunol 2013 0.80
67 Endothelial precursor cells and CRP on the RAGE: activation or cell death? J Cardiovasc Pharmacol 2009 0.78
68 A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies). Biochem Biophys Res Commun 2006 0.78
69 Soluble forms of RAGE: an index of vascular stress? A commentary on "Soluble RAGE in type 2 diabetes: association with oxidative stress". Free Radic Biol Med 2007 0.77
70 Anomaly in aortic arch alters pathological outcome of transient global ischemia in Rhesus macaques. Brain Res 2009 0.75
71 The marriage of glucose and blood vessels: it isn't all that sweet. Cell Metab 2005 0.75
72 A highly reproducible model of cerebral ischemia/reperfusion with extended survival in CB-17 mice. Neurosci Res 2013 0.75