Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation.

PubWeight™: 1.07‹?› | Rank: Top 10%

🔗 View Article (PMID 12453185)

Published in Pigment Cell Res on December 01, 2002

Authors

M Cathy Scott1, Itaru Suzuki, Zalfa A Abdel-Malek

Author Affiliations

1: Department of Dermatology, University of Cincinnati, Cincinnati, Ohio 45267-592, USA.

Articles citing this

Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3. J Invest Dermatol (2012) 1.01

Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis. Int J Mol Sci (2011) 1.00

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation. Pigment Cell Melanoma Res (2014) 0.97

Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans. Pigment Cell Melanoma Res (2009) 0.96

Melasma: a clinical and epidemiological review. An Bras Dermatol (2014) 0.95

Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes. J Invest Dermatol (2015) 0.90

Barrier requirements as the evolutionary "driver" of epidermal pigmentation in humans. Am J Hum Biol (2010) 0.89

Shining light on skin pigmentation: the darker and the brighter side of effects of UV radiation. Photochem Photobiol (2012) 0.85

In vivo identification of solar radiation-responsive gene network: role of the p38 stress-dependent kinase. PLoS One (2010) 0.81

Malignant melanoma and melanocortin 1 receptor. Biochemistry (Mosc) (2013) 0.81

Investigation of safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of a long-acting α-MSH analog in healthy overweight and obese subjects. J Clin Pharmacol (2013) 0.81

Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children. BMC Public Health (2014) 0.78

Benefits of oral Polypodium Leucotomos extract in MM high-risk patients. J Eur Acad Dermatol Venereol (2012) 0.78

ASSESSMENT OF MC1R AND α-MSH GENE SEQUENCES IN IRANIAN VITILIGO PATIENTS. Indian J Dermatol (2010) 0.76

Pregnancy and estrogen receptor beta expression in a large congenital nevus. Arch Dermatol (2009) 0.76

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor. PLoS One (2015) 0.76

Neutron activation analysis and X-ray Rayleigh and Raman scattering of hair and nail clippings as noninvasive bioindicators for Cu liver status in Labrador Retrievers. Anal Bioanal Chem (2008) 0.75

Articles by these authors

alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes. Cancer Res (2005) 1.58

Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol (2004) 1.56

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. FASEB J (2010) 1.23

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res (2006) 1.20

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci (2002) 1.19

MC1R and the response of melanocytes to ultraviolet radiation. Mutat Res (2005) 1.18

Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round? Pigment Cell Res (2003) 1.07

Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3. J Invest Dermatol (2012) 1.01

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation. Pigment Cell Melanoma Res (2014) 0.94

Mitogen- and ultraviolet-B-induced signaling pathways in normal human melanocytes. J Invest Dermatol (2002) 0.94

Cutaneous photoprotection and melanoma susceptibility: reaching beyond melanin content to the frontiers of DNA repair. Front Biosci (2006) 0.92

Transcriptional profiling shows altered expression of wnt pathway- and lipid metabolism-related genes as well as melanogenesis-related genes in melasma. J Invest Dermatol (2011) 0.92

Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes. FASEB J (2001) 0.87

In vivo reflectance confocal microscopy detects pigmentary changes in melasma at a cellular level resolution. Exp Dermatol (2010) 0.87

Regulation of constitutive and UVR-induced skin pigmentation by melanocortin 1 receptor isoforms. FASEB J (2006) 0.85

Melanin-concentrating hormone and its receptor are expressed and functional in human skin. Biochem Biophys Res Commun (2002) 0.79

Endothelin-1 protects human melanocytes from UV-induced DNA damage by activating JNK and p38 signalling pathways. Exp Dermatol (2015) 0.79

Messenger RNA levels of melanogenesis-associated genes in lentigo senilis lesions. J Dermatol Sci (2004) 0.78

Agouti signal protein: crossing the 'yellow' signal and arriving to pathways that affect tumorgenesis. Pigment Cell Melanoma Res (2009) 0.76

Human skin melanocyte migration towards stromal cell-derived factor-1α demonstrated by optical real-time cell mobility assay: modulation of their chemotactic ability by α-melanocyte-stimulating hormone. Exp Dermatol (2013) 0.76

Walking in the footsteps of giants: melanocortins and human pigmentation, a historical perspective. Pigment Cell Res (2007) 0.76

UV increases the nuclear localization of apurinic/apyrimidinic endonuclease/redox effector factor-1 in human skin. J Invest Dermatol (2006) 0.75