Published in J Clin Pharmacol on December 01, 2002
Study of the Urinary Ratio of 6 beta-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases. Biomark Insights (2007) 0.77
Absence of Drug-Drug Interactions Between Luseogliflozin, a Sodium-Glucose Co-transporter-2 Inhibitor, and Various Oral Antidiabetic Drugs in Healthy Japanese Males. Adv Ther (2015) 0.76
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet (2009) 8.11
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum (2004) 3.92
The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study. Mov Disord (2007) 3.04
A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology (2004) 2.75
Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat Cell Biol (2006) 2.57
Emerging patterns of somatic mutations in cancer. Nat Rev Genet (2013) 2.50
Neuromyelitis optica: Passive transfer to rats by human immunoglobulin. Biochem Biophys Res Commun (2009) 2.20
Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1. Hum Mol Genet (2005) 2.07
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature (2002) 2.04
SIK2 is a key regulator for neuronal survival after ischemia via TORC1-CREB. Neuron (2011) 2.03
Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients. Mov Disord (2007) 1.85
Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease. J Neurosci (2008) 1.64
PPARalpha protects proximal tubular cells from acute fatty acid toxicity. J Am Soc Nephrol (2007) 1.62
MTHFR gene polymorphism as a risk factor for diabetic retinopathy in type 2 diabetic patients without serum creatinine elevation. Diabetes Care (2003) 1.56
Role of the prefrontal cortex in human balance control. Neuroimage (2008) 1.48
Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells. Biochem Biophys Res Commun (2010) 1.40
Nrf2 regulates haematopoietic stem cell function. Nat Cell Biol (2013) 1.38
Role of antioxidant activity of taurine in diabetes. Can J Physiol Pharmacol (2009) 1.31
Antipsychotics reverse abnormal EEG complexity in drug-naive schizophrenia: a multiscale entropy analysis. Neuroimage (2010) 1.23
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes. Cardiovasc Res (2008) 1.22
Glycoprotein 130 cytokine signal as a therapeutic target against cardiovascular diseases. J Pharmacol Sci (2011) 1.21
Benefit of valproic acid in suppressing disease progression of ALS model mice. Eur J Neurosci (2004) 1.21
Assessment of EEG dynamical complexity in Alzheimer's disease using multiscale entropy. Clin Neurophysiol (2010) 1.20
Astrocytic necrosis is induced by anti-aquaporin-4 antibody-positive serum. Neuroreport (2009) 1.19
Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction. Circulation (2010) 1.14
Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes. J Neurosci (2011) 1.14
Local nucleosome dynamics facilitate chromatin accessibility in living mammalian cells. Cell Rep (2012) 1.14
A novel method for systematic analysis of rigidity in Parkinson's disease. Mov Disord (2009) 1.14
ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry (2007) 1.14
Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus. J Biol Chem (2004) 1.14
Physiological roles of taurine in heart and muscle. J Biomed Sci (2010) 1.13
NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: a randomized controlled trial for pharmacogenetics-based therapy. Eur J Clin Pharmacol (2012) 1.12
Connective tissue growth factor induces cardiac hypertrophy through Akt signaling. Biochem Biophys Res Commun (2008) 1.12
Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development (2005) 1.12
Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers. Arch Ophthalmol (2008) 1.11
STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart. Cardiovasc Res (2005) 1.11
Membrane clustering and the role of rebinding in biochemical signaling. Biophys J (2012) 1.09
Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy. J Mol Cell Cardiol (2008) 1.08
Proton MR spectroscopic study at 3 Tesla on glutamate/glutamine in Alzheimer's disease. Neuroreport (2002) 1.08
Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmacogenetics (2002) 1.07
Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells. Biochem J (2004) 1.07
Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population. Neuroreport (2007) 1.05
Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production. Amino Acids (2011) 1.05
A hump-backed trend in bacterial diversity with elevation on Mount Fuji, Japan. Microb Ecol (2011) 1.05
Relationship between cerebral blood flow and later cognitive decline in hypertensive patients with cerebral small vessel disease. Hypertens Res (2009) 1.04
Modulation of astrocyte proliferation by cyclin-dependent kinase inhibitor p27(Kip1). Glia (2002) 1.04
Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome. Am J Physiol Cell Physiol (2004) 1.04
N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes. Biochem Biophys Res Commun (2005) 1.03
New mutation of the Na channel in the severe form of potassium-aggravated myotonia. Muscle Nerve (2009) 1.03
A quantitative model of ERK MAP kinase phosphorylation in crowded media. Sci Rep (2013) 1.03
Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: role of DNA damage. Am J Physiol Heart Circ Physiol (2003) 1.02
Identification of cardiac myocytes as the target of interleukin 11, a cardioprotective cytokine. Cytokine (2007) 1.02
Measurement and evaluation of finger tapping movements using magnetic sensors. Conf Proc IEEE Eng Med Biol Soc (2008) 1.02
Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.02
Sodium tanshinone IIA sulfonate derived from Danshen (Salvia miltiorrhiza) attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac cells. Biochem Pharmacol (2002) 1.02
Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients. Neuropsychobiology (2006) 1.01
Why is taurine cytoprotective? Adv Exp Med Biol (2003) 1.01
Ibudilast, a nonselective phosphodiesterase inhibitor, regulates Th1/Th2 balance and NKT cell subset in multiple sclerosis. Mult Scler (2004) 1.00
Reduced tongue pressure against the hard palate on the paralyzed side during swallowing predicts Dysphagia in patients with acute stroke. Stroke (2010) 1.00
Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives. Bioorg Med Chem Lett (2005) 1.00
Frontal regions involved in learning of motor skill--A functional NIRS study. Neuroimage (2006) 1.00
Identification of influx transporter for the quinolone antibacterial agent levofloxacin. Mol Pharm (2007) 0.99
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle. Acta Neuropathol (2007) 0.99
Sustained prefrontal activation during ataxic gait: a compensatory mechanism for ataxic stroke? Neuroimage (2007) 0.99
Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes. J Biol Chem (2006) 0.99
LDOC1, a novel MZF-1-interacting protein, induces apoptosis. FEBS Lett (2005) 0.99
The potential usefulness of taurine on diabetes mellitus and its complications. Amino Acids (2011) 0.98
Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE. Drug Metab Pharmacokinet (2005) 0.98
Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway. Biochem Biophys Res Commun (2004) 0.98
N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes. J Mol Cell Cardiol (2006) 0.98
Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity: difference in metabolism as a possible mechanism. J Clin Oncol (2011) 0.98
PPAR{alpha} attenuates the proinflammatory response in activated mesangial cells. Am J Physiol Renal Physiol (2008) 0.97
Cerebral small vessel disease and incident parkinsonism: the RUN DMC study. Neurology (2016) 0.97
Relationship between tongue pressure and dysphagia in stroke patients. Eur Neurol (2010) 0.97
In vitro free radical scavenging activity of platinum nanoparticles. Nanotechnology (2009) 0.96
Effect of 5-HT1A gene polymorphisms on antidepressant response in major depressive disorder. Am J Med Genet B Neuropsychiatr Genet (2009) 0.96
Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk myelodysplastic syndrome is associated with poor prognosis and transformation to acute myelogenous leukemia. Am J Hematol (2013) 0.96
Age-related variation in EEG complexity to photic stimulation: a multiscale entropy analysis. Clin Neurophysiol (2009) 0.96
Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells. Hypertens Res (2003) 0.95
Antibacterial and antiproliferative activity of cationic fullerene derivatives. Bioorg Med Chem Lett (2003) 0.95
Rac1 activity is required for cardiac myocyte alignment in response to mechanical stress. Biochem Biophys Res Commun (2006) 0.95
No positive association between adrenergic receptor variants of alpha2cDel322-325, beta1Ser49, beta1Arg389 and the risk for heart failure in the Japanese population. Br J Clin Pharmacol (2005) 0.95
Finger taps movement acceleration measurement system for quantitative diagnosis of Parkinson's disease. Conf Proc IEEE Eng Med Biol Soc (2006) 0.95
Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes. FEBS Lett (2004) 0.95