Tatsuhiko Kodama

Author PubWeight™ 310.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007 13.56
2 Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 2006 9.36
3 Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 2002 9.10
4 Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med 2011 5.66
5 Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006 5.63
6 Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev 2005 5.50
7 Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 2004 4.92
8 Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006 4.13
9 Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci U S A 2003 4.03
10 HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 2009 3.86
11 Osteoprotection by semaphorin 3A. Nature 2012 3.40
12 NFAT and Osterix cooperatively regulate bone formation. Nat Med 2005 2.99
13 Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas. Clin Cancer Res 2005 2.97
14 Global gene expression analysis of gastric cancer by oligonucleotide microarrays. Cancer Res 2002 2.49
15 Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest 2003 2.48
16 Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab 2011 2.42
17 Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Nat Cell Biol 2008 2.35
18 Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma. Cancer Res 2004 2.34
19 Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation. Mol Cell 2004 2.31
20 The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development 2006 2.27
21 A wave of nascent transcription on activated human genes. Proc Natl Acad Sci U S A 2009 2.18
22 Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell 2008 2.13
23 Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. J Biol Chem 2004 2.05
24 Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med 2012 2.04
25 Suppression of bone formation by osteoclastic expression of semaphorin 4D. Nat Med 2011 2.00
26 Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. EMBO J 2009 1.94
27 Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med 2006 1.93
28 Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95. J Cell Biol 2009 1.91
29 A simple method of isolating mouse aortic endothelial cells. J Atheroscler Thromb 2005 1.88
30 The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop. Mol Cell Biol 2009 1.78
31 Ets motifs are necessary for endothelial cell-specific expression of a 723-bp Tie-2 promoter/enhancer in Hprt targeted transgenic mice. Arterioscler Thromb Vasc Biol 2003 1.72
32 Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris. Arterioscler Thromb Vasc Biol 2006 1.72
33 Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3. Blood 2009 1.68
34 COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis. Proc Natl Acad Sci U S A 2009 1.67
35 Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A 2005 1.65
36 The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases. Cell Rep 2013 1.61
37 Bilirubin from heme oxygenase-1 attenuates vascular endothelial activation and dysfunction. Arterioscler Thromb Vasc Biol 2004 1.59
38 Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling. Int J Cancer 2003 1.54
39 Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest 2010 1.54
40 The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma. Mod Pathol 2005 1.52
41 Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development. Mol Cell Biol 2003 1.48
42 Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver. J Atheroscler Thromb 2015 1.45
43 The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses. Infect Immun 2002 1.45
44 Determination of physiological plasma pentraxin 3 (PTX3) levels in healthy populations. Clin Chem Lab Med 2009 1.43
45 Active RNA polymerases: mobile or immobile molecular machines? PLoS Biol 2010 1.37
46 Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature 2013 1.35
47 Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer. Cancer Res 2008 1.35
48 Blimp1-mediated repression of negative regulators is required for osteoclast differentiation. Proc Natl Acad Sci U S A 2010 1.34
49 A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage. J Atheroscler Thromb 2004 1.34
50 Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. Am J Pathol 2006 1.33
51 Pulmonary surfactant protein A augments the phagocytosis of Streptococcus pneumoniae by alveolar macrophages through a casein kinase 2-dependent increase of cell surface localization of scavenger receptor A. J Biol Chem 2004 1.33
52 Gene expression profiling of potential peroxisome proliferator-activated receptor (PPAR) target genes in human hepatoblastoma cell lines inducibly expressing different PPAR isoforms. Nucl Recept 2005 1.32
53 Pathological role of osteoclast costimulation in arthritis-induced bone loss. Proc Natl Acad Sci U S A 2007 1.32
54 Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation. J Pharmacol Exp Ther 2010 1.31
55 Thrombin and phenotypic modulation of the endothelium. Arterioscler Thromb Vasc Biol 2003 1.31
56 Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species. Free Radic Biol Med 2006 1.29
57 Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells 2009 1.28
58 An opposing view on WWOX protein function as a tumor suppressor. Cancer Res 2003 1.27
59 Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium. J Biol Chem 2006 1.27
60 Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol Cell Biol 2012 1.26
61 Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation. PLoS Genet 2011 1.24
62 SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation. J Biol Chem 2007 1.24
63 A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2. J Biol Chem 2004 1.24
64 Association of active gamma-secretase complex with lipid rafts. J Lipid Res 2005 1.24
65 TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed. EMBO J 2012 1.21
66 Three-dimensional structure of the gamma-secretase complex. Biochem Biophys Res Commun 2006 1.21
67 Residual macrovascular risk in 2013: what have we learned? Cardiovasc Diabetol 2014 1.20
68 Macrophage scavenger receptor down-regulates mycobacterial cord factor-induced proinflammatory cytokine production by alveolar and hepatic macrophages. Microb Pathog 2006 1.20
69 Lipid accumulation in smooth muscle cells under LDL loading is independent of LDL receptor pathway and enhanced by hypoxic conditions. Arterioscler Thromb Vasc Biol 2002 1.20
70 The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells. J Atheroscler Thromb 2002 1.20
71 Overexpression of MUC13 is associated with intestinal-type gastric cancer. Cancer Sci 2005 1.19
72 Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins. J Atheroscler Thromb 2005 1.18
73 Anti-glypican 3 antibodies cause ADCC against human hepatocellular carcinoma cells. Biochem Biophys Res Commun 2008 1.16
74 Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. Arterioscler Thromb Vasc Biol 2006 1.14
75 SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. J Biol Chem 2005 1.14
76 Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins. J Cell Mol Med 2007 1.13
77 Lipid raft microdomains mediate class A scavenger receptor-dependent infection of Brucella abortus. Microb Pathog 2004 1.13
78 Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation. Diabetes 2007 1.13
79 Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients. Neurosci Lett 2009 1.13
80 Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression. EMBO J 2011 1.13
81 Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development 2010 1.13
82 Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta-NF-kappa B and PKC-zeta-GATA signaling pathways. J Biol Chem 2002 1.12
83 Fasting-induced hypothermia and reduced energy production in mice lacking acetyl-CoA synthetase 2. Cell Metab 2009 1.11
84 Identification of genes associated with dedifferentiation of hepatocellular carcinoma with expression profiling analysis. Jpn J Cancer Res 2002 1.11
85 Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clin Cancer Res 2006 1.11
86 Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle. J Biol Chem 2013 1.11
87 Defective microarchitecture of the spleen marginal zone and impaired response to a thymus-independent type 2 antigen in mice lacking scavenger receptors MARCO and SR-A. J Immunol 2005 1.11
88 Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells. J Biol Chem 2009 1.11
89 Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA. Proc Natl Acad Sci U S A 2006 1.10
90 Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8. Mol Cell Biol 2007 1.10
91 Selective reconstitution and recovery of functional gamma-secretase complex on budded baculovirus particles. J Biol Chem 2004 1.10
92 Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling. J Biol Chem 2004 1.09
93 Identification of Cystatin SN as a novel tumor marker for colorectal cancer. Int J Oncol 2009 1.09
94 Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms. Eur J Cell Biol 2011 1.08
95 The class A scavenger receptor binds to proteoglycans and mediates adhesion of macrophages to the extracellular matrix. J Biol Chem 2002 1.08
96 The generation of monoclonal antibodies against human peroxisome proliferator-activated receptors (PPARs). J Atheroscler Thromb 2002 1.08
97 Global analysis of shear stress-responsive genes in vascular endothelial cells. J Atheroscler Thromb 2003 1.07
98 Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2. J Biol Chem 2008 1.06
99 Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats. J Cereb Blood Flow Metab 2004 1.06
100 Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF. Cancer Sci 2008 1.05
101 Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling. J Clin Invest 2007 1.04
102 Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9. Mol Cell Biol 2008 1.04
103 Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2. Arterioscler Thromb Vasc Biol 2004 1.03
104 Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitis. Pathol Int 2011 1.03
105 Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system. Free Radic Biol Med 2004 1.03
106 Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Atherosclerosis 2008 1.03
107 Glypican-3 expression in clear cell adenocarcinoma of the ovary. Mod Pathol 2009 1.03
108 Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma. Clin Cancer Res 2007 1.03
109 Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells. J Biol Chem 2009 1.03
110 Requirement of the IFN-alpha/beta-induced CXCR3 chemokine signalling for CD8+ T cell activation. Genes Cells 2002 1.02
111 Targeted deletion of class A macrophage scavenger receptor increases the risk of cardiac rupture after experimental myocardial infarction. Circulation 2007 1.02
112 Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and rats. Nucl Recept 2003 1.02
113 A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus. Evidence for Galpha and Galphao coupling to a human leukotriene B4 receptor. J Biol Chem 2003 1.02
114 Gene expression profile during acute rejection in rat-to-mouse concordant cardiac xenograft by means of DNA microarray. Transpl Int 2002 1.01
115 Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis. Proc Natl Acad Sci U S A 2011 1.01
116 Production, characterization, and interspecies reactivities of monoclonal antibodies against human class A macrophage scavenger receptors. Atherosclerosis 2002 1.01
117 The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci 2009 1.00
118 Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter. Mol Cell Biol 2011 1.00
119 Plasma Pentraxin3 is a novel marker for nonalcoholic steatohepatitis (NASH). BMC Gastroenterol 2008 0.99
120 Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages. Cancer Res 2013 0.99
121 Global analysis of RNA expression profile in human vascular cells treated with statins. J Atheroscler Thromb 2004 0.99
122 Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants. Free Radic Biol Med 2003 0.99
123 Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling. Circ Res 2011 0.98
124 Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation. Traffic 2006 0.98
125 Mannose-binding lectin augments the uptake of lipid A, Staphylococcus aureus, and Escherichia coli by Kupffer cells through increased cell surface expression of scavenger receptor A. J Immunol 2006 0.97
126 The expression profiles of nuclear receptors in the developing and adult kidney. Mol Endocrinol 2006 0.97
127 Sall1, a causative gene for Townes-Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin. Biochem Biophys Res Commun 2004 0.97
128 GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation. Genes Cells 2013 0.96
129 Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface. J Biol Chem 2008 0.96
130 The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular traps. Mol Cell Proteomics 2012 0.96
131 Oncofetal protein glypican-3 in testicular germ-cell tumor. Virchows Arch 2006 0.96
132 A serum amyloid A and LDL complex as a new prognostic marker in stable coronary artery disease. Atherosclerosis 2004 0.96
133 Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors. J Biol Chem 2010 0.96
134 Viral envelope protein gp64 transgenic mouse facilitates the generation of monoclonal antibodies against exogenous membrane proteins displayed on baculovirus. J Immunol Methods 2007 0.96
135 Ly49Q, an ITIM-bearing NK receptor, positively regulates osteoclast differentiation. Biochem Biophys Res Commun 2010 0.95
136 Pentraxin 3: a novel biomarker for inflammatory cardiovascular disease. Int J Vasc Med 2012 0.95
137 A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. FASEB J 2003 0.94
138 Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes. J Pharmacol Sci 2011 0.94
139 Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease. Blood 2004 0.94
140 The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice. J Clin Invest 2009 0.94
141 Identification of CCR2, flotillin, and gp49B genes as new G-CSF targets during neutrophilic differentiation. J Leukoc Biol 2005 0.93
142 The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma. Histopathology 2011 0.93
143 Expression of Dlk/Pref-1 defines a subpopulation in the oval cell compartment of rat liver. Gene Expr Patterns 2004 0.93
144 Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma. Biochem J 2006 0.93
145 Fucoidan induces nitric oxide production via p38 mitogen-activated protein kinase and NF-kappaB-dependent signaling pathways through macrophage scavenger receptors. Biochem Biophys Res Commun 2006 0.92
146 Reciprocal contribution of pentraxin 3 and C-reactive protein to obesity and metabolic syndrome. Obesity (Silver Spring) 2010 0.92
147 Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1. J Cell Sci 2011 0.91
148 Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression. Biochem Biophys Res Commun 2002 0.91
149 Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cell. FASEB J 2005 0.91
150 Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells. FEBS Lett 2010 0.91
151 Heterogeneity in immunohistochemical, genomic, and biological properties of human lymphatic endothelial cells between initial and collecting lymph vessels. Lymphat Res Biol 2008 0.89
152 Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob. J Biol Chem 2012 0.89
153 Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways. J Biol Chem 2012 0.89
154 Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals. Neurosci Lett 2010 0.89
155 The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-kappa B ligand-stimulated induction of nuclear factor of activated T cells c1. Arthritis Rheum 2004 0.89
156 Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver. FEBS Lett 2004 0.89
157 Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. Biochem Biophys Res Commun 2005 0.89
158 The expression pattern of nuclear receptors during cerebellar development. Dev Dyn 2007 0.89
159 HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors. Biochem Biophys Res Commun 2002 0.89
160 cAMP cascade (PKA, Epac, adenylyl cyclase, Gi, and phosphodiesterases) regulates myelin phagocytosis mediated by complement receptor-3 and scavenger receptor-AI/II in microglia and macrophages. Glia 2006 0.88
161 Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204). Dev Dyn 2005 0.88
162 Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome. Pharmacol Res 2006 0.88
163 Downregulated P1 promoter-driven hepatocyte nuclear factor-4alpha expression in human colorectal carcinoma is a new prognostic factor against liver metastasis. Pathol Int 2007 0.88
164 Identification of human low-density lipoprotein receptor as a novel target gene regulated by liver X receptor alpha. FEBS Lett 2006 0.88
165 Non-PKC DAG/phorbol-ester receptor(s) inhibit complement receptor-3 and nPKC inhibit scavenger receptor-AI/II-mediated myelin phagocytosis but cPKC, PI3k, and PLCgamma activate myelin phagocytosis by both. Glia 2006 0.87
166 Single chain variable fragment against nicastrin inhibits the gamma-secretase activity. J Biol Chem 2009 0.87
167 Analysis of PPAR alpha function in human kidney cell line using siRNA. Nucleic Acids Symp Ser (Oxf) 2006 0.87
168 Characterization and microarray analysis of genes in human lymphatic endothelial cells from patients with breast cancer. Lymphat Res Biol 2007 0.87
169 Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a manner dependent on its dileucine motif. Mol Endocrinol 2002 0.87
170 Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns 2007 0.87
171 Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues. Biochem Biophys Res Commun 2005 0.86
172 Regulation of the human PDZK1 expression by peroxisome proliferator-activated receptor alpha. FEBS Lett 2008 0.86
173 Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages. Neurobiol Dis 2004 0.86
174 Essential role of GATA transcriptional factors in the activation of mast cells. J Immunol 2007 0.86
175 Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells. Biochem J 2010 0.85
176 Molecular diversity of TEX101, a marker glycoprotein for germ cells monitored with monoclonal antibodies: variety of the molecular characteristics according to subcellular localization within the mouse testis. J Reprod Immunol 2008 0.85
177 Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages. Cancer Sci 2009 0.85
178 Different distribution of pentraxin 3 and C-reactive protein in coronary atherosclerotic plaques. J Atheroscler Thromb 2012 0.84
179 Expression of liver X receptor alpha in rat fetal tissues at different developmental stages. J Histochem Cytochem 2007 0.84
180 Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer. Cancer Sci 2011 0.84
181 Mutations for decreasing the immunogenicity and maintaining the function of core streptavidin. Protein Sci 2013 0.84
182 Expression of hepatocyte nuclear factor 4 alpha in primary ovarian mucinous tumors. Pathol Int 2008 0.84
183 Associations of plasma pentraxin 3 and monocyte chemoattractant protein-1 concentrations with cardiovascular disease in patients with chronic kidney disease. Ren Fail 2011 0.83
184 Immunohistochemical staining for P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha may complement mucin phenotype of differentiated-type early gastric carcinoma. Pathol Int 2009 0.83
185 Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. J Clin Invest 2012 0.83
186 Hepatitis C virus core protein binds to a C-terminal region of NS5B RNA polymerase. Hepatol Res 2002 0.83
187 Oxidized low density lipoprotein-induced LFA-1-dependent adhesion and transendothelial migration of monocytes via the protein kinase C pathway. Atherosclerosis 2002 0.83
188 The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice. Invest Ophthalmol Vis Sci 2009 0.83
189 Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab 2002 0.82
190 Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ubiquinone levels in rat skeletal muscle and heart: relationship to cytotoxicity and inhibitory activity for cholesterol synthesis in human skeletal muscle cells. J Atheroscler Thromb 2006 0.82
191 Lipopolysaccharide induced expression of pentraxin 3 in human neutrophils and monocyte-derived macrophages. Cell Immunol 2007 0.82
192 Phosphatidylinositol-4-phosphate 5-kinase gamma is associated with cell-cell junction in A431 epithelial cells. Cell Biol Int 2005 0.82
193 Human calpain 7/PalBH associates with a subset of ESCRT-III-related proteins in its N-terminal region and partly localizes to endocytic membrane compartments. J Biochem 2008 0.82
194 Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities. Hepatology 2012 0.81
195 Effect of BO-653 and probucol on c-MYC and PDGF-A messenger RNA of the iliac artery after balloon denudation in cholesterol-fed rabbits. Atherosclerosis 2002 0.81
196 Recovery of functional peptide transporter PepT1 in budded baculovirus fraction. Protein Expr Purif 2005 0.81
197 Expression of the LXRalpha protein in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2004 0.81
198 Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system. J Biotechnol 2008 0.81
199 Detection of an up-regulation of a group of chemokine genes in murine cardiac allograft in the absence of interferon-gamma by means of DNA microarray. Transplantation 2002 0.80
200 Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade. Physiol Genomics 2003 0.80
201 A simple detection method for low-affinity membrane protein interactions by baculoviral display. PLoS One 2008 0.80
202 Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-kappaB (RANK). Biochem Biophys Res Commun 2009 0.80
203 Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies. Biochem Biophys Res Commun 2013 0.80
204 Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression. Gene Expr 2012 0.79
205 Chemical structure-dependent gene expression of proteasome subunits via regulation of the antioxidant response element. Free Radic Res 2006 0.79
206 Protein expression of nuclear receptors in human and murine tissues. Pathol Int 2009 0.79
207 Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma. Am J Pathol 2013 0.79
208 Identification and characterization of the X-dimer of human P-cadherin: implications for homophilic cell adhesion. Biochemistry 2014 0.79
209 Extensive oligonucleotide microarray transcriptome analysis of the rat cerebral artery and arachnoid tissue. J Atheroscler Thromb 2002 0.79
210 Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas. Cancer Sci 2009 0.79
211 Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements. Genome Biol 2014 0.78
212 Cellular-automaton model of the cooperative dynamics of RNA polymerase II during transcription in human cells. Phys Rev E Stat Nonlin Soft Matter Phys 2011 0.78
213 Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies. Hybridoma (Larchmt) 2012 0.78
214 A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization. J Biol Chem 2008 0.78
215 A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine. Free Radic Biol Med 2003 0.78
216 A proteomic profiling of laser-microdissected lung adenocarcinoma cells of early lepidic-types. Clin Transl Med 2015 0.78
217 Regulation of the human SLC25A20 expression by peroxisome proliferator-activated receptor alpha in human hepatoblastoma cells. Biochem Biophys Res Commun 2009 0.78
218 In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding. Virology 2009 0.78
219 COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells. Exp Eye Res 2009 0.78
220 Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants. J Med Chem 2003 0.77
221 Expression of liver X receptor alpha and lipid metabolism in granulocyte-macrophage colony-stimulating factor-induced human monocyte-derived macrophage. Pathol Int 2009 0.77
222 A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells. J Immunol Methods 2011 0.77
223 RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand. J Gen Virol 2010 0.77
224 Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin. Mol Biosyst 2012 0.77
225 The feasibility of an efficient drug design method with high-performance computers. Chem Pharm Bull (Tokyo) 2015 0.77
226 Molecular dynamics simulation-based evaluation of the binding free energies of computationally designed drug candidates: importance of the dynamical effects. Chem Pharm Bull (Tokyo) 2014 0.77
227 Prominent expression of FRS2beta protein in neural cells and its association with intracellular vesicles. FEBS Lett 2009 0.76
228 The role of the BH3-only protein Noxa in bone homeostasis. Biochem Biophys Res Commun 2011 0.76
229 Transcriptional activation by hypoxia and low-density lipoprotein loading in cultured vascular smooth muscle cells. J Atheroscler Thromb 2007 0.76
230 A novel method for viral display of ER membrane proteins on budded baculovirus. Biochem Biophys Res Commun 2003 0.76
231 Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses. Protein Sci 2015 0.76
232 Design and synthesis of biotin analogues reversibly binding with streptavidin. Chem Asian J 2015 0.76
233 Human mannose-binding lectin 2 is directly regulated by peroxisome proliferator-activated receptors via a peroxisome proliferator responsive element. J Biochem 2013 0.76
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