|
1
|
Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes.
|
J Biol Chem
|
2003
|
2.27
|
|
2
|
Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding.
|
J Mol Biol
|
2004
|
1.57
|
|
3
|
Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP.
|
Cancer Res
|
2004
|
1.36
|
|
4
|
Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants.
|
Biochemistry
|
2005
|
1.29
|
|
5
|
Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation.
|
J Immunol
|
2004
|
1.23
|
|
6
|
The sugar code: functional lectinomics.
|
Biochim Biophys Acta
|
2002
|
1.14
|
|
7
|
Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases.
|
J Neuropathol Exp Neurol
|
2002
|
1.14
|
|
8
|
Quaternary solution structures of galectins-1, -3, and -7.
|
Glycobiology
|
2003
|
1.13
|
|
9
|
Tumor galectinology: insights into the complex network of a family of endogenous lectins.
|
Glycoconj J
|
2004
|
1.11
|
|
10
|
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells.
|
Oncogene
|
2003
|
1.05
|
|
11
|
Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting.
|
Cancer
|
2003
|
1.04
|
|
12
|
Atypical adenomatous hyperplasia of lung: its incidence and analysis of clinical, glycohistochemical and structural features including newly defined growth regulators and vascularization.
|
Lung Cancer
|
2003
|
1.04
|
|
13
|
Effects of polyvalency of glycotopes and natural modifications of human blood group ABH/Lewis sugars at the Galbeta1-terminated core saccharides on the binding of domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N).
|
Biochimie
|
2004
|
1.03
|
|
14
|
Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins.
|
Biochemistry
|
2003
|
1.02
|
|
15
|
Galectin-1 knocking down in human U87 glioblastoma cells alters their gene expression pattern.
|
Biochem Biophys Res Commun
|
2005
|
1.00
|
|
16
|
Up-regulation of galectin-3 and its ligands by Trypanosoma cruzi infection with modulation of adhesion and migration of murine dendritic cells.
|
Glycobiology
|
2004
|
0.98
|
|
17
|
Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancer.
|
Ann Surg Oncol
|
2006
|
0.97
|
|
18
|
Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration.
|
Lab Invest
|
2002
|
0.97
|
|
19
|
Localized fibrous tumors (LFTs) of the pleura: clinical data, asbestos burden, and syntactic structure analysis applied to newly defined angiogenic/growth-regulatory effectors.
|
Pathol Res Pract
|
2005
|
0.96
|
|
20
|
Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications.
|
Mod Pathol
|
2002
|
0.95
|
|
21
|
Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival.
|
APMIS
|
2002
|
0.95
|
|
22
|
Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets.
|
Bioconjug Chem
|
2004
|
0.94
|
|
23
|
A regulatory network of two galectins mediates the earliest steps of avian limb skeletal morphogenesis.
|
BMC Dev Biol
|
2011
|
0.92
|
|
24
|
Galectin-3 - an emerging prognostic indicator in advanced head and neck carcinoma.
|
Eur J Cancer
|
2004
|
0.90
|
|
25
|
Nuclear galectin-3 expression is an independent predictive factor of recurrence for adenocarcinoma and squamous cell carcinoma of the lung.
|
Mod Pathol
|
2005
|
0.89
|
|
26
|
Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.
|
Org Biomol Chem
|
2003
|
0.89
|
|
27
|
Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair.
|
Cells Tissues Organs
|
2011
|
0.88
|
|
28
|
Calix[n]arene-based glycoclusters: bioactivity of thiourea-linked galactose/lactose moieties as inhibitors of binding of medically relevant lectins to a glycoprotein and cell-surface glycoconjugates and selectivity among human adhesion/growth-regulatory galectins.
|
Chembiochem
|
2008
|
0.87
|
|
29
|
Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on binding of the endogenous lectins galectins-1 and -3.
|
APMIS
|
2002
|
0.87
|
|
30
|
Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: increased expression of galectin-1 and induction of poor prognosis factors.
|
Int J Cancer
|
2012
|
0.86
|
|
31
|
Detection and chromatographic removal of lipopolysaccharide in preparations of multifunctional galectins.
|
Biochem Biophys Res Commun
|
2008
|
0.86
|
|
32
|
Binding sites for Lewis antigens are expressed by human colon cancer cells and negatively affect their migration.
|
Lab Invest
|
2003
|
0.86
|
|
33
|
Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential.
|
Histopathology
|
2011
|
0.86
|
|
34
|
Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population.
|
Biochim Biophys Acta
|
2012
|
0.85
|
|
35
|
Cell-type-specific expression of murine multifunctional galectin-3 and its association with follicular atresia/luteolysis in contrast to pro-apoptotic galectins-1 and -7.
|
Histochem Cell Biol
|
2008
|
0.85
|
|
36
|
Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target.
|
Expert Opin Ther Targets
|
2013
|
0.85
|
|
37
|
Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoprotein.
|
Arthritis Res Ther
|
2013
|
0.84
|
|
38
|
Human galectins as sensors for apoptosis/necrosis-associated surface changes of granulocytes and lymphocytes.
|
Cytometry A
|
2008
|
0.84
|
|
39
|
Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7.
|
Int J Oncol
|
2009
|
0.83
|
|
40
|
High level of galectin-1 expression is a negative prognostic predictor of recurrence in laryngeal squamous cell carcinomas.
|
Int J Oncol
|
2007
|
0.83
|
|
41
|
Fine specificity of domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N).
|
Biochem J
|
2002
|
0.82
|
|
42
|
Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy.
|
Biochim Biophys Acta
|
2008
|
0.82
|
|
43
|
Phosphorylation of adhesion- and growth-regulatory human galectin-3 leads to the induction of axonal branching by local membrane L1 and ERM redistribution.
|
J Cell Sci
|
2010
|
0.82
|
|
44
|
Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
|
Glycobiology
|
2012
|
0.82
|
|
45
|
Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells.
|
Int J Cancer
|
2005
|
0.82
|
|
46
|
Chromosomal aberrations, profiles of expression of growth-related markers including galectins and environmental hazards in relation to the incidence of chondroid pulmonary hamartomas.
|
Pathol Res Pract
|
2003
|
0.81
|
|
47
|
Adhesion/growth-regulatory galectins in the human eye: localization profiles and tissue reactivities as a standard to detect disease-associated alterations.
|
Graefes Arch Clin Exp Ophthalmol
|
2012
|
0.81
|
|
48
|
Carbohydrate chain of ganglioside GM1 as a ligand: identification of the binding strategies of three 15 mer peptides and their divergence from the binding modes of growth-regulatory galectin-1 and cholera toxin.
|
Chemistry
|
2005
|
0.81
|
|
49
|
Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.
|
J Neurochem
|
2013
|
0.81
|
|
50
|
Macrophage migration inhibitory factor in head and neck squamous cell carcinoma: clinical and experimental studies.
|
J Cancer Res Clin Oncol
|
2013
|
0.80
|
|
51
|
Expression patterns of galectin-1 and galectin-3 in nasal polyps and middle and inferior turbinates in relation to growth regulation and immunosuppression.
|
Arch Otolaryngol Head Neck Surg
|
2003
|
0.80
|
|
52
|
Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.
|
Histochem Cell Biol
|
2005
|
0.80
|
|
53
|
Galectins as tools for glycan mapping in histology: comparison of their binding profiles to the bovine zona pellucida by confocal laser scanning microscopy.
|
Histochem Cell Biol
|
2011
|
0.80
|
|
54
|
Unique sequence and expression profiles of rat galectins-5 and -9 as a result of species-specific gene divergence.
|
Int J Biochem Cell Biol
|
2006
|
0.80
|
|
55
|
Hydrodynamic properties of human adhesion/growth-regulatory galectins studied by fluorescence correlation spectroscopy.
|
Biophys J
|
2010
|
0.80
|
|
56
|
Increased expression of macrophage migration inhibitory factor during progression to hypopharyngeal squamous cell carcinoma.
|
Anticancer Res
|
2010
|
0.80
|
|
57
|
Carbamate-linked lactose: design of clusters and evidence for selectivity to block binding of human lectins to (neo)glycoproteins with increasing degree of branching and to tumor cells.
|
Bioconjug Chem
|
2009
|
0.80
|
|
58
|
Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin.
|
Cells Tissues Organs
|
2002
|
0.79
|
|
59
|
Galectin-8 up-regulation during hypopharyngeal and laryngeal tumor progression and comparison with galectin-1, -3 and -7.
|
Anticancer Res
|
2009
|
0.79
|
|
60
|
Open Wound Healing In Vivo: Monitoring Binding and Presence of Adhesion/Growth-Regulatory Galectins in Rat Skin during the Course of Complete Re-Epithelialization.
|
Acta Histochem Cytochem
|
2011
|
0.79
|
|
61
|
N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution.
|
Int J Biochem Cell Biol
|
2010
|
0.79
|
|
62
|
Homodimeric chicken galectin CG-1B (C-14): Crystal structure and detection of unique redox-dependent shape changes involving inter- and intrasubunit disulfide bridges by gel filtration, ultracentrifugation, site-directed mutagenesis, and peptide mass fingerprinting.
|
J Mol Biol
|
2008
|
0.78
|
|
63
|
Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas.
|
J Oral Pathol Med
|
2012
|
0.78
|
|
64
|
Analysis of homodimeric avian and human galectins by two methods based on fluorescence spectroscopy: different structural alterations upon oxidation and ligand binding.
|
Biochimie
|
2012
|
0.77
|
|
65
|
Describing topology of bound ligand by transferred nuclear Overhauser effect spectroscopy and molecular modeling.
|
Methods Enzymol
|
2003
|
0.77
|
|
66
|
Identification of peptide ligands for malignancy- and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries.
|
Bioorg Med Chem
|
2005
|
0.77
|
|
67
|
A lectin from the Chinese bird-hunting spider binds sialic acids.
|
Carbohydr Res
|
2009
|
0.77
|
|
68
|
Adhesion/growth-regulatory galectins: insights into their ligand selectivity using natural glycoproteins and glycotopes.
|
Adv Exp Med Biol
|
2011
|
0.77
|
|
69
|
Fine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlations.
|
Acta Crystallogr D Biol Crystallogr
|
2013
|
0.77
|
|
70
|
Toward functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster.
|
Histochem Cell Biol
|
2004
|
0.77
|
|
71
|
Association of galectin-1- but not galectin-3-dependent parameters with proliferation activity in human neuroblastomas and small cell lung carcinomas.
|
Anticancer Res
|
2002
|
0.77
|
|
72
|
alpha2,3/alpha2,6-Sialylation of N-glycans: non-synonymous signals with marked developmental regulation in bovine reproductive tracts.
|
Biochimie
|
2005
|
0.76
|
|
73
|
Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.
|
Bioorg Med Chem Lett
|
2011
|
0.76
|
|
74
|
Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected].
|
Ann N Y Acad Sci
|
2012
|
0.76
|
|
75
|
Characterization of the levels of expression of retinoic acid receptors, galectin-3, macrophage migration inhibiting factor, and p53 in 51 adamantinomatous craniopharyngiomas.
|
J Neurosurg
|
2003
|
0.76
|
|
76
|
Glucocorticoid-induced differential expression of the sialylated and nonsialylated Lewis(a) epitopes and respective binding sites in human nasal polyps maintained under ex vivo tissue culture conditions.
|
Ann Otol Rhinol Laryngol
|
2002
|
0.76
|
|
77
|
Hippocampal neurons and recombinant galectins as tools for systematic carbohydrate structure-function studies in neuronal differentiation.
|
Brain Res Dev Brain Res
|
2004
|
0.75
|
|
78
|
Differential stimulation of VEGF-C production by adhesion/growth-regulatory galectins and plant lectins in human breast cancer cells.
|
Anticancer Res
|
2010
|
0.75
|
|
79
|
Monitoring the expression profiles of integrins and adhesion/growth-regulatory galectins in adamantinomatous craniopharyngiomas: their ability to regulate tumor adhesiveness to surrounding tissue and their contribution to prognosis.
|
Neurosurgery
|
2005
|
0.75
|
|
80
|
Analysis of selected blood and immune cell responses to carbohydrate-dependent surface binding of proto- and chimera-type galectins.
|
Mol Cell Biochem
|
2003
|
0.75
|
|
81
|
Molecular biological fingerprinting of human lectin expression by RT-PCR.
|
Methods Enzymol
|
2003
|
0.75
|
|
82
|
Comparative phenotypic characterization of keratinocytes originating from hair follicles.
|
J Mol Histol
|
2005
|
0.75
|
|
83
|
Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy.
|
Analyst
|
2011
|
0.75
|
|
84
|
Playing Modular Puzzle with Adhesion/Growth-Regulatory Galectins: Design and Testing of a Hybrid to Unravel Structure-Activity Relationships.
|
Protein Pept Lett
|
2016
|
0.75
|