Published in Dev Biol on December 15, 2002
Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation. PLoS Genet (2008) 2.67
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The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart. Mech Dev (2002) 1.05
Genetically distinct cardial cells within the Drosophila heart. Genesis (2000) 1.05
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Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell Metab (2006) 1.99
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Mol Biol Cell (2007) 1.81
Even-skipped, acting as a repressor, regulates axonal projections in Drosophila. Development (2003) 1.77
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APJ acts as a dual receptor in cardiac hypertrophy. Nature (2012) 1.62
Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila. Nature (2003) 1.57
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. Aging Cell (2008) 1.52
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proc Natl Acad Sci U S A (2006) 1.51
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Screening assays for heart function mutants in Drosophila. Biotechniques (2004) 1.43
Slit and Robo control cardiac cell polarity and morphogenesis. Curr Biol (2005) 1.41
Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons. Mol Neurodegener (2008) 1.37
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Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development (2006) 1.36
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d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell (2009) 1.31
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A Drosophila model of high sugar diet-induced cardiomyopathy. PLoS Genet (2013) 1.28
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Images in cardiovascular medicine: in vivo imaging of the adult Drosophila melanogaster heart with real-time optical coherence tomography. Circulation (2006) 1.21
sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr Biol (2002) 1.20
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev (2011) 1.16
Semi-automated Optical Heartbeat Analysis of small hearts. J Vis Exp (2009) 1.15
A complex array of DNA-binding proteins required for pairing-sensitive silencing by a polycomb group response element from the Drosophila engrailed gene. Genetics (2002) 1.13
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Drawing lines in the sand: even skipped et al. and parasegment boundaries. Dev Biol (2004) 1.09
Gata factor Pannier is required to establish competence for heart progenitor formation. Development (2003) 1.08
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The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. J Exp Biol (2008) 1.01
The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundaries. Development (2002) 1.01
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Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development. Mol Cell (2011) 0.99
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. J Cell Mol Med (2012) 0.98
Sestrins at the crossroad between stress and aging. Aging (Albany NY) (2010) 0.98
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PLoS One (2011) 0.97
Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan. Circ Res (2005) 0.97
Non-additive interactions involving two distinct elements mediate sloppy-paired regulation by pair-rule transcription factors. Dev Biol (2010) 0.96
Specification of motoneuron fate in Drosophila: integration of positive and negative transcription factor inputs by a minimal eve enhancer. J Neurobiol (2003) 0.96
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol (2011) 0.95
MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation. Genes Cells (2002) 0.93
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. PLoS One (2012) 0.93
Partial loss of GATA factor Pannier impairs adult heart function in Drosophila. Hum Mol Genet (2009) 0.93
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS Genet (2011) 0.92
Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila. Development (2003) 0.91
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell (2013) 0.90
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Identification of genetic loci that interact with cut during Drosophila wing-margin development. Genetics (2005) 0.90
Lipotoxicity and cardiac dysfunction in mammals and Drosophila. Crit Rev Biochem Mol Biol (2011) 0.90
Regulation of parkin and PINK1 by neddylation. Hum Mol Genet (2012) 0.90
A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell (2014) 0.90
Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction. J Cell Mol Med (2012) 0.89
The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis. Genetics (2002) 0.89
Hedgehog and RAS pathways cooperate in the anterior-posterior specification and positioning of cardiac progenitor cells. Dev Biol (2006) 0.89
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Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development. Dev Genes Evol (2006) 0.88
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The Drosophila homolog of vertebrate Islet1 is a key component in early cardiogenesis. Development (2008) 0.85
Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. Dev Biol (2009) 0.85
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Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers. Dev Biol (2011) 0.84
Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen. PLoS Genet (2013) 0.84
A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE. Mol Cells (2008) 0.83
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway. Mol Cell Biochem (2007) 0.83
Cardiac aging. Semin Cell Dev Biol (2006) 0.82
Probing the polygenic basis of cardiomyopathies in Drosophila. J Cell Mol Med (2012) 0.82
The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading. PLoS Genet (2013) 0.82
A comparative study of pulse rate variability and heart rate variability in healthy subjects. J Clin Monit Comput (2012) 0.82
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Drosophila aging 2005/06. Exp Gerontol (2006) 0.81