Published in Curr Opin Clin Nutr Metab Care on January 01, 2003
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci U S A (2006) 5.28
Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. J Physiol (2006) 1.66
Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J Biol Chem (2010) 1.66
The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy. Pflugers Arch (2011) 1.41
A meta-analysis of exercise interventions among people treated for cancer. Support Care Cancer (2006) 1.40
Cachexia in patients with oesophageal cancer. Nat Rev Clin Oncol (2015) 1.05
Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women. PLoS One (2009) 1.05
The effect of exercise on IL-6-induced cachexia in the Apc ( Min/+) mouse. J Cachexia Sarcopenia Muscle (2011) 1.03
Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise. J Cachexia Sarcopenia Muscle (2011) 0.97
Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial. PLoS One (2012) 0.96
Troponin T nuclear localization and its role in aging skeletal muscle. Age (Dordr) (2011) 0.93
The effect of resistance exercise to augment long-term benefits of intradialytic oral nutritional supplementation in chronic hemodialysis patients. J Ren Nutr (2010) 0.87
Exercise as a Time-conditioning Effector in Chronic Disease: a Complementary Treatment Strategy. Evid Based Complement Alternat Med (2004) 0.84
Nutrition and exercise in the management of liver cirrhosis. World J Gastroenterol (2014) 0.83
Exercise and Cancer Treatment Symptoms in 408 Newly Diagnosed Older Cancer Patients. J Geriatr Oncol (2012) 0.83
Cachectic skeletal muscle response to a novel bout of low-frequency stimulation. J Appl Physiol (1985) (2014) 0.81
Exercise as an anabolic intervention in patients with end-stage renal disease. J Ren Nutr (2011) 0.81
Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment. BMC Pulm Med (2013) 0.80
Eccentric contraction-induced myofiber growth in tumor-bearing mice. J Appl Physiol (1985) (2015) 0.77
Human Skeletal Muscle Disuse Atrophy: Effects on Muscle Protein Synthesis, Breakdown, and Insulin Resistance-A Qualitative Review. Front Physiol (2016) 0.76
Treatment with a corticotrophin releasing factor 2 receptor agonist modulates skeletal muscle mass and force production in aged and chronically ill animals. BMC Musculoskelet Disord (2011) 0.75
Pathway to independence: physical therapy for patients with rheumatoid arthritis. MedGenMed (2004) 0.75
Relation between serum myokines and phase II cardiac rehabilitation. Medicine (Baltimore) (2017) 0.75
Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science (2010) 8.04
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med (2006) 5.09
A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system. Ann Neurol (2009) 4.59
Effects of extended outpatient rehabilitation after hip fracture: a randomized controlled trial. JAMA (2004) 2.89
Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial. J Am Geriatr Soc (2002) 2.80
Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle. J Clin Endocrinol Metab (2004) 2.47
Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol (2008) 2.20
State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Circulation (2008) 2.17
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells. Blood (2012) 1.89
HIV-protease inhibitors impair vitamin D bioactivation to 1,25-dihydroxyvitamin D. AIDS (2003) 1.66
Insulin sensitivity by oral glucose minimal models: validation against clamp. Am J Physiol Endocrinol Metab (2005) 1.50
Mechanical ventilation depresses protein synthesis in the rat diaphragm. Am J Respir Crit Care Med (2004) 1.50
Effects of progressive resistance training on body composition in frail older adults: results of a randomized, controlled trial. J Gerontol A Biol Sci Med Sci (2005) 1.48
Testosterone and growth hormone improve body composition and muscle performance in older men. J Clin Endocrinol Metab (2009) 1.40
Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers. Sci Transl Med (2013) 1.38
Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. J Am Soc Mass Spectrom (2007) 1.33
Development of appropriate coronary heart disease risk prediction models in HIV-infected patients. Circulation (2008) 1.24
Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice. Am J Pathol (2008) 1.16
Whole-body proteolysis rate is elevated in HIV-associated insulin resistance. Diabetes (2006) 1.14
Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound. J Neurosci (2010) 1.09
The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution. Qual Life Res (2008) 1.07
Exercise training reduces central adiposity and improves metabolic indices in HAART-treated HIV-positive subjects in Rwanda: a randomized controlled trial. AIDS Res Hum Retroviruses (2008) 1.07
Evaluation of early biomarkers of muscle anabolic response to testosterone. J Cachexia Sarcopenia Muscle (2011) 1.03
Niacin in HIV-infected individuals with hyperlipidemia receiving potent antiretroviral therapy. Clin Infect Dis (2004) 1.02
Amprenavir and efavirenz pharmacokinetics before and after the addition of nelfinavir, indinavir, ritonavir, or saquinavir in seronegative individuals. Antimicrob Agents Chemother (2005) 1.01
Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy. Metabolism (2005) 1.00
PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans. Am J Physiol Endocrinol Metab (2006) 1.00
Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women. J Am Geriatr Soc (2003) 0.96
Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation. Appl Environ Microbiol (2014) 0.95
Insulin resistance predicts endothelial dysfunction and cardiovascular risk in HIV-infected persons on long-term highly active antiretroviral therapy. AIDS (2008) 0.91
HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus. Am J Physiol Endocrinol Metab (2008) 0.91
A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin-induced diabetes. Exp Neurol (2005) 0.88
HIV-protease inhibitors suppress skeletal muscle fatty acid oxidation by reducing CD36 and CPT1 fatty acid transporters. Biochim Biophys Acta (2010) 0.88
Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization. Am J Physiol Endocrinol Metab (2010) 0.88
Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation. Eur J Appl Physiol (2011) 0.87
Evaluation of high-protein supplementation in weight-stable HIV-positive subjects with a history of weight loss: a randomized, double-blind, multicenter trial. Am J Clin Nutr (2008) 0.87
Nutrient ingestion, protein intake, and sex, but not age, affect the albumin synthesis rate in humans. J Nutr (2007) 0.87
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS. PLoS One (2012) 0.86
Treatment with oxandrolone and the durability of effects in older men. J Appl Physiol (1985) (2003) 0.85
1H-magnetic resonance spectroscopy for quantifying myocardial lipid content in humans with the cardiometabolic syndrome. J Clin Hypertens (Greenwich) (2009) 0.85
Age and sex affect protein metabolism at protein intakes that span the range of adequacy: comparison of leucine kinetics and nitrogen balance data. J Nutr Biochem (2012) 0.84
A randomized, placebo-controlled trial of nandrolone decanoate in human immunodeficiency virus-infected men with mild to moderate weight loss with recombinant human growth hormone as active reference treatment. J Clin Endocrinol Metab (2005) 0.84
Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans. J Nutr (2004) 0.82
Hormonal regulators of muscle and metabolism in aging (HORMA): design and conduct of a complex, double masked multicenter trial. Clin Trials (2007) 0.82
Magnetic resonance imaging for quantifying regional adipose tissue in human immunodeficiency virus-infected persons with the cardiometabolic syndrome. J Cardiometab Syndr (2008) 0.82
Protease inhibitors used in the treatment of HIV+ induce beta-cell apoptosis via the mitochondrial pathway and compromise insulin secretion. Am J Physiol Endocrinol Metab (2009) 0.81
Durability of the effects of testosterone and growth hormone supplementation in older community-dwelling men: the HORMA Trial. Clin Endocrinol (Oxf) (2011) 0.81
Dipeptidyl peptidase IV inhibition does not adversely affect immune or virological status in HIV infected men and women: a pilot safety study. J Clin Endocrinol Metab (2012) 0.81
In vivo kinetic approach reveals slow SOD1 turnover in the CNS. J Clin Invest (2015) 0.81
Blunted lipolysis and fatty acid oxidation during moderate exercise in HIV-infected subjects taking HAART. Am J Physiol Endocrinol Metab (2006) 0.81
Effects of human immunodeficiency virus and metabolic complications on myocardial nutrient metabolism, blood flow, and oxygen consumption: a cross-sectional analysis. Cardiovasc Diabetol (2011) 0.81
Cortisol and its action on the glucocorticoid receptor in malnutrition and acute infection. Metabolism (2006) 0.80
Antiretroviral Drug Levels and Interactions Affect Lipid, Lipoprotein, and Glucose Metabolism in HIV-1 Seronegative Subjects: A Pharmacokinetic-Pharmacodynamic Analysis. Metab Syndr Relat Disord (2007) 0.79
Whole-body leucine kinetics and the acute phase response during acute infection in marasmic Malawian children. Pediatr Res (2004) 0.79
Insulin is protein-anabolic in chronic renal failure patients. J Am Soc Nephrol (2003) 0.79
Pharmacokinetic interaction between efavirenz and dual protease inhibitors in healthy volunteers. Biopharm Drug Dispos (2008) 0.78
Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks. Antimicrob Agents Chemother (2007) 0.78
Cardiometabolic disease in the human immunodeficiency virus: the tip of the iceberg? J Cardiometab Syndr (2008) 0.77
Muscle protein synthesis in younger and older men. JAMA (2002) 0.76
Relationships among HIV infection, metabolic risk factors, and left ventricular structure and function. AIDS Res Hum Retroviruses (2013) 0.75
Urea production and leucine oxidation in malnourished children with and without acute infection. Metabolism (2002) 0.75