Published in Ann N Y Acad Sci on November 01, 2002
Differential regulation of EHD3 in human and mammalian heart failure. J Mol Cell Cardiol (2012) 1.02
EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology. Circ Res (2014) 0.88
Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm (2011) 2.21
Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs. Circulation (2004) 2.09
Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation. Circulation (2003) 2.06
Assessing predictors of drug-induced torsade de pointes. Trends Pharmacol Sci (2003) 1.97
Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. Heart Rhythm (2012) 1.91
Biology of cardiac sodium channel Nav1.5 expression. Cardiovasc Res (2011) 1.86
In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome. Cardiovasc Res (2007) 1.80
Characterization of in vitro and in vivo lesions made by a novel multichannel ablation generator and a circumlinear decapolar ablation catheter. J Cardiovasc Electrophysiol (2009) 1.62
Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation. Am J Physiol Heart Circ Physiol (2008) 1.60
Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes. Stem Cell Res (2010) 1.51
Increased phospholamban phosphorylation limits the force-frequency response in the MLP-/- mouse with heart failure. J Mol Cell Cardiol (2006) 1.49
Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy? Cardiovasc Res (2002) 1.45
Absence of reverse electrical remodeling during regression of volume overload hypertrophy in canine ventricles. Cardiovasc Res (2003) 1.45
Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes. J Physiol (2003) 1.39
Microvolt T-wave alternans and beat-to-beat variability of repolarization during early postischemic remodeling in a pig heart. Heart Rhythm (2011) 1.38
Evolutionary origin of inhibitor cystine knot peptides. FASEB J (2003) 1.31
Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias. Pharmacol Ther (2006) 1.30
Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysis. PLoS Comput Biol (2013) 1.30
Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient. J Mol Cell Cardiol (2011) 1.29
A novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gating. Hum Mutat (2003) 1.27
Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model. J Am Coll Cardiol (2010) 1.26
Beat-to-Beat variability of repolarization determines proarrhythmic outcome in dogs susceptible to drug-induced torsades de pointes. J Am Coll Cardiol (2006) 1.25
Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis. Cardiovasc Res (2003) 1.23
Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation. Cardiovasc Res (2010) 1.22
Proteome-wide protein concentrations in the human heart. Mol Biosyst (2010) 1.21
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J Mol Cell Cardiol (2012) 1.20
Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias. Eur J Heart Fail (2010) 1.15
Spatial and temporal inhomogeneities during Ca2+ release from the sarcoplasmic reticulum in pig ventricular myocytes. Circ Res (2002) 1.14
Proarrhythmic electrical remodelling is associated with increased beat-to-beat variability of repolarisation. Cardiovasc Res (2006) 1.12
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nat Cell Biol (2013) 1.11
Reorganized PKA-AKAP associations in the failing human heart. J Mol Cell Cardiol (2011) 1.10
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and highly abundant AKAP. J Proteome Res (2006) 1.09
Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur J Biochem (2002) 1.09
Arrhythmogenic right ventricular dysplasia/cardiomyopathy diagnostic task force criteria: impact of new task force criteria. Circ Arrhythm Electrophysiol (2010) 1.07
Na/Ca exchange and cardiac ventricular arrhythmias. Ann N Y Acad Sci (2007) 1.07
P2X1 ion channels promote neutrophil chemotaxis through Rho kinase activation. J Immunol (2009) 1.05
Biomarkers of myocardial fibrosis. J Cardiovasc Pharmacol (2011) 1.05
Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study. Eur Heart J (2007) 1.04
Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block. J Physiol (2006) 1.03
Usefulness of short-term variability of QT intervals as a predictor for electrical remodeling and proarrhythmia in patients with nonischemic heart failure. Am J Cardiol (2010) 1.02
Novel insights in the congenital long QT syndrome. Ann Intern Med (2002) 1.01
Intracellular Na+ and altered Na+ transport mechanisms in cardiac hypertrophy and failure. J Mol Cell Cardiol (2003) 1.01
Molecular and electrical characterization of the canine cardiac ventricular septum. J Mol Cell Cardiol (2004) 1.01
Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1. Circ Res (2011) 1.00
Short-term variability of repolarization predicts ventricular tachycardia and sudden cardiac death in patients with structural heart disease: a comparison with QT variability index. Heart Rhythm (2011) 0.99
Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation. Circ Res (2012) 0.98
Beat-to-beat variability of repolarization as a new biomarker for proarrhythmia in vivo. Heart Rhythm (2012) 0.98
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity. Circ Arrhythm Electrophysiol (2012) 0.98
Diversity of cAMP-dependent protein kinase isoforms and their anchoring proteins in mouse ventricular tissue. J Proteome Res (2007) 0.98
Inhibition of cardiomyocyte automaticity by electrotonic application of inward rectifier current from Kir2.1 expressing cells. Med Biol Eng Comput (2006) 0.97
Direct detection of myocardial fibrosis by MRI. J Mol Cell Cardiol (2011) 0.96
Relation of increased short-term variability of QT interval to congenital long-QT syndrome. Am J Cardiol (2009) 0.95
Combined Na(+)/Ca(2+) exchanger and L-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function. Circ Arrhythm Electrophysiol (2013) 0.93
Sudden cardiac death in dogs with remodeled hearts is associated with larger beat-to-beat variability of repolarization. Basic Res Cardiol (2005) 0.93
I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation. J Mol Cell Cardiol (2009) 0.92
Beta-, not alpha-adrenergic stimulation enhances conduction velocity in cultures of neonatal cardiomyocytes. Circ J (2007) 0.92
Increased Na+ concentration and altered Na/K pump activity in hypertrophied canine ventricular cells. Cardiovasc Res (2003) 0.92
The canine model with chronic, complete atrio-ventricular block. Pharmacol Ther (2008) 0.91
Temporal patterns of electrical remodeling in canine ventricular hypertrophy: focus on IKs downregulation and blunted beta-adrenergic activation. Cardiovasc Res (2006) 0.90
Lysosome mediated Kir2.1 breakdown directly influences inward rectifier current density. Biochem Biophys Res Commun (2008) 0.90
Connexin43 repression following epithelium-to-mesenchyme transition in embryonal carcinoma cells requires Snail1 transcription factor. Differentiation (2007) 0.89
Evolutionary trace analysis of scorpion toxins specific for K-channels. Proteins (2004) 0.89
Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. Eur J Biochem (2002) 0.89
Asynchronous development of electrical remodeling and cardiac hypertrophy in the complete AV block dog. Cardiovasc Res (2003) 0.88
Tridimensional activation patterns of acquired torsade-de-pointes tachycardias in dogs with chronic AV-block. Basic Res Cardiol (2004) 0.87
Electrophysiological safety of sertindole in dogs with normal and remodeled hearts. J Pharmacol Exp Ther (2003) 0.87
Experimental Mapping of the Canine KCNJ2 and KCNJ12 Gene Structures and Functional Analysis of the Canine K(IR)2.2 ion Channel. Front Physiol (2012) 0.87
Phosphoproteomics study based on in vivo inhibition reveals sites of calmodulin-dependent protein kinase II regulation in the heart. J Am Heart Assoc (2013) 0.86
Cellular basis for triggered ventricular arrhythmias that occur in the setting of compensated hypertrophy and heart failure: considerations for diagnosis and treatment. J Electrocardiol (2007) 0.86
Atrial-specific drugs: the way to treat atrial fibrillation? J Cardiovasc Electrophysiol (2004) 0.86
Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. Am J Physiol Heart Circ Physiol (2007) 0.85
Atrial-specific drug AVE0118 is free of torsades de pointes in anesthetized dogs with chronic complete atrioventricular block. Heart Rhythm (2006) 0.85
Arrhythmogenic mechano-electric heterogeneity in the long-QT syndrome. Prog Biophys Mol Biol (2012) 0.85
Improvement of cardiac efficacy and safety models in drug discovery by the use of stem cell-derived cardiomyocytes. Expert Opin Drug Discov (2009) 0.85
The JT-area indicates dispersion of repolarization in dogs with atrioventricular block. J Interv Card Electrophysiol (2002) 0.85
Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue. Basic Res Cardiol (2014) 0.85
Drug-induced torsade de pointes arrhythmias in the chronic AV block dog are perpetuated by focal activity. Circ Arrhythm Electrophysiol (2011) 0.84
Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue. Cardiovasc Res (2013) 0.83
High-rate pacing reduces variability of repolarization and prevents repolarization-dependent arrhythmias in dogs with chronic AV block. J Cardiovasc Electrophysiol (2010) 0.83
Beat-to-beat variability of repolarization: a new parameter to determine arrhythmic risk of an individual or identify proarrhythmic drugs. Anadolu Kardiyol Derg (2007) 0.83
Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA, and EAPCI task force. Europace (2014) 0.83
Circadian rhythms in cell maturation. Physiology (Bethesda) (2014) 0.83