Published in Physiol Rev on January 01, 2003
PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science (2009) 2.84
Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses. Nat Neurosci (2009) 1.83
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
A screen of cell-surface molecules identifies leucine-rich repeat proteins as key mediators of synaptic target selection. Neuron (2008) 1.45
Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex. Neuron (2011) 1.38
Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion. EMBO J (2006) 1.28
The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Proc Natl Acad Sci U S A (2010) 1.28
Genetic determinants at the interface of cancer and neurodegenerative disease. Oncogene (2010) 1.17
Protein tyrosine phosphatases PTPδ, PTPσ, and LAR: presynaptic hubs for synapse organization. Trends Neurosci (2013) 1.16
Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4. J Cell Biol (2005) 1.13
The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2. Hum Mol Genet (2011) 1.06
Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development. Mol Cell Biol (2006) 1.06
Receptor protein tyrosine phosphatases and cancer: new insights from structural biology. Cell Adh Migr (2012) 1.00
Dimerization of protein tyrosine phosphatase sigma governs both ligand binding and isoform specificity. Mol Cell Biol (2006) 0.99
LAR receptor tyrosine phosphatases and HSPGs guide peripheral sensory axons to the skin. Curr Biol (2012) 0.97
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn. EMBO J (2009) 0.95
Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases. BMC Genomics (2008) 0.94
Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-sigma. FEBS J (2006) 0.92
Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily. Neural Dev (2008) 0.92
The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Mol Cell Biol (2004) 0.92
Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity. J Neurosci (2013) 0.92
The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism. Proc Natl Acad Sci U S A (2009) 0.91
Small-molecule protein tyrosine phosphatase inhibition as a neuroprotective treatment after spinal cord injury in adult rats. J Neurosci (2008) 0.91
Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling. Development (2009) 0.91
The receptor tyrosine phosphatase Lar regulates adhesion between Drosophila male germline stem cells and the niche. Development (2012) 0.90
Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis. Nat Commun (2014) 0.90
The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance. J Neurosci (2011) 0.87
Receptor tyrosine phosphatases regulate birth order-dependent axonal fasciculation and midline repulsion during development of the Drosophila mushroom body. Mol Cell Neurosci (2008) 0.87
The immunoglobulin-like domains 1 and 2 of the protein tyrosine phosphatase LAR adopt an unusual horseshoe-like conformation. J Mol Biol (2011) 0.86
E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner. Mol Cell Neurosci (2007) 0.86
Protein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system. Mol Cell Neurosci (2009) 0.86
The novel protein PTPIP51 exhibits tissue- and cell-specific expression. Histochem Cell Biol (2004) 0.86
Receptor-type tyrosine phosphatase ligands: looking for the needle in the haystack. FEBS J (2012) 0.86
Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase. Philos Trans R Soc Lond B Biol Sci (2013) 0.85
Genomic structure and alternative splicing of murine R2B receptor protein tyrosine phosphatases (PTPkappa, mu, rho and PCP-2). BMC Genomics (2004) 0.85
The beneficial effects of C-Peptide on diabetic polyneuropathy. Rev Diabet Stud (2009) 0.84
Orchestrating the synaptic network by tyrosine phosphorylation signalling. J Biochem (2011) 0.84
Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1. Cell (2015) 0.84
Rho GTPases regulate PTPmu-mediated nasal neurite outgrowth and temporal repulsion of retinal ganglion cell neurons. Mol Cell Neurosci (2007) 0.83
NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells. EMBO J (2016) 0.83
Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach. PLoS One (2012) 0.83
PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proc Natl Acad Sci U S A (2015) 0.82
Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila. Biol Open (2012) 0.82
Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity. PLoS One (2011) 0.81
Unmyelinated auditory type I spiral ganglion neurons in congenic Ly5.1 mice. J Comp Neurol (2010) 0.81
Identification of tyrosine phosphatase ligands for contactin cell adhesion molecules. Commun Integr Biol (2010) 0.80
Oxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61. J Neurochem (2011) 0.80
Phosphatase regulation of intercellular junctions. Tissue Barriers (2013) 0.80
Accelerated axonal loss following acute CNS demyelination in mice lacking protein tyrosine phosphatase receptor type Z. Am J Pathol (2012) 0.80
Organization of F-actin via concerted regulation of Kette by PTP61F and dAbl. Mol Cell Biol (2009) 0.79
Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells. PLoS One (2012) 0.79
Differential activities in adhesion and neurite growth of fibronectin type III repeats in the PTP-delta extracellular domain. Int J Dev Neurosci (2006) 0.79
The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. Mol Cell Biol (2009) 0.79
Splicing-Dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion. Cell Rep (2015) 0.79
Distinct PTPmu-associated signaling molecules differentially regulate neurite outgrowth on E-, N-, and R-cadherin. Mol Cell Neurosci (2010) 0.79
Novel mechanisms of tube-size regulation revealed by the Drosophila trachea. Cell Tissue Res (2013) 0.78
SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development. Sci Rep (2016) 0.78
Modulation of catalytic activity in multi-domain protein tyrosine phosphatases. PLoS One (2011) 0.77
Extracellular regulation of type IIa receptor protein tyrosine phosphatases: mechanistic insights from structural analyses. Semin Cell Dev Biol (2014) 0.76
Identification of novel, less toxic PTP-LAR inhibitors using in silico strategies: pharmacophore modeling, SADMET-based virtual screening and docking. J Mol Model (2011) 0.76
Protein tyrosine phosphatase receptor type O (Ptpro) regulates cerebellar formation during zebrafish development through modulating Fgf signaling. Cell Mol Life Sci (2013) 0.76
An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma. J Transl Med (2016) 0.76
Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal development. BMB Rep (2015) 0.75
PTPBR7 binding proteins in myelinating neurons of the mouse brain. Int J Biol Sci (2011) 0.75
Crystallization and preliminary X-ray diffraction studies on the catalytic domain of the chick retinal neurite-inhibitory factor CRYP-2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.75
A Synthetic Lethal Screen Identifies a Role for Lin-44/Wnt in C. elegans Embryogenesis. PLoS One (2015) 0.75
Receptor tyrosine phosphatase CLR-1 acts in skin cells to promote sensory dendrite outgrowth. Dev Biol (2016) 0.75
Abnormal myelination in the spinal cord of PTPα-knockout mice. Cell Adh Migr (2013) 0.75
Identification of receptor-type protein tyrosine phosphatase μ as a new marker for osteocytes. Histochem Cell Biol (2015) 0.75
Developmental expression and function analysis of protein tyrosine phosphatase receptor type D in oligodendrocyte myelination. Neuroscience (2015) 0.75
A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. PLoS One (2017) 0.75
Linking cortical microtubule attachment and exocytosis. F1000Res (2017) 0.75
The trip of the tip: understanding the growth cone machinery. Nat Rev Mol Cell Biol (2009) 3.38
Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis. Neuron (2002) 2.33
Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms. Nat Methods (2009) 2.32
The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Neuron (2006) 1.98
The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance. Neuron (2004) 1.92
Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance. Curr Biol (2004) 1.77
Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila. Development (2007) 1.76
Modeling spinal muscular atrophy in Drosophila. PLoS One (2008) 1.71
MicroRNAs shape the neuronal landscape. Neuron (2012) 1.64
Direct observation demonstrates that Liprin-alpha is required for trafficking of synaptic vesicles. Curr Biol (2005) 1.57
A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron (2002) 1.23
A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. Development (2012) 1.16
miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons. PLoS One (2012) 1.13
Conserved genes act as modifiers of invertebrate SMN loss of function defects. PLoS Genet (2010) 1.07
Understanding neuronal connectivity through the post-transcriptional toolkit. Genes Dev (2010) 1.06
Synapses and growth cones on two sides of a highwire. Neuron (2008) 1.00
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau. J Clin Invest (2015) 0.99
GAPs in Slit-Robo signaling. Bioessays (2002) 0.97
Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth. Neural Dev (2013) 0.96
Complex interactions amongst N-cadherin, DLAR, and Liprin-alpha regulate Drosophila photoreceptor axon targeting. Dev Biol (2009) 0.96
Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth. Neural Dev (2008) 0.95
The heparan sulfate proteoglycans Dally-like and Syndecan have distinct functions in axon guidance and visual-system assembly in Drosophila. Curr Biol (2005) 0.95
Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics. Mol Cell Biol (2013) 0.93
Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlar in vivo. Mol Cell Biol (2003) 0.89
Neural Explant Cultures from Xenopus laevis. J Vis Exp (2012) 0.89
Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. Proc Natl Acad Sci U S A (2013) 0.86
Heparan sulfate proteoglycan specificity during axon pathway formation in the Drosophila embryo. Dev Neurobiol (2011) 0.86
MicroRNA-276a functions in ellipsoid body and mushroom body neurons for naive and conditioned olfactory avoidance in Drosophila. J Neurosci (2013) 0.85
Catalyzing curriculum evolution in graduate science education. Cell (2013) 0.84
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet (2013) 0.83
Drosophila growth cones advance by forward translocation of the neuronal cytoskeletal meshwork in vivo. PLoS One (2013) 0.82
miR-8 controls synapse structure by repression of the actin regulator enabled. Development (2014) 0.82
Neurons take shape. Curr Biol (2003) 0.81
Robo is Abl to block N-Cadherin function. Nat Cell Biol (2002) 0.78
Synapse specificity: Wnts keep motor axons on target. Curr Biol (2007) 0.78
Drosophila semaphorin2b is required for the axon guidance of a subset of embryonic neurons. Dev Dyn (2013) 0.77
Embryonic and larval neural connectivity: progressive changes in synapse form and function at the neuromuscular junction mediated by cytoskeletal regulation. Wiley Interdiscip Rev Dev Biol (2013) 0.76
Maintaining muscle mitochondria via transsynaptic signaling. Dev Cell (2012) 0.75