Published in Am J Pathol on January 01, 2003
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest (2003) 3.31
Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization. Am J Pathol (2006) 2.52
Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am J Pathol (2003) 2.37
Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY43-9006). Am J Pathol (2006) 1.66
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents. Cancer Treat Rev (2010) 1.64
Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. J Clin Invest (2007) 1.47
Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer. Neoplasia (2009) 1.34
Stromal cell-derived factor-1alpha activation of tissue-engineered endothelial progenitor cell matrix enhances ventricular function after myocardial infarction by inducing neovasculogenesis. Circulation (2010) 1.28
Neovascularization after irradiation: what is the source of newly formed vessels in recurring tumors? J Natl Cancer Inst (2012) 1.19
Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye. EMBO J (2005) 1.06
The antivascular action of physiotherapy ultrasound on murine tumors. Ultrasound Med Biol (2005) 1.02
Acute myocardial rescue with endogenous endothelial progenitor cell therapy. Heart Lung Circ (2010) 1.01
Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. Am J Pathol (2007) 1.00
A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Math Biosci (2010) 0.97
Laser photocoagulation enhances adeno-associated viral vector transduction of mouse retina. Hum Gene Ther Methods (2013) 0.94
MT-MMPS as Regulators of Vessel Stability Associated with Angiogenesis. Front Pharmacol (2011) 0.94
Tumor vessel stabilization and remodeling by anti-angiogenic therapy with bevacizumab. Histochem Cell Biol (2011) 0.93
Tissue-engineered pro-angiogenic fibroblast scaffold improves myocardial perfusion and function and limits ventricular remodeling after infarction. J Thorac Cardiovasc Surg (2010) 0.92
Recruitment and retention: factors that affect pericyte migration. Cell Mol Life Sci (2013) 0.90
Desmin expression in colorectal cancer stroma correlates with advanced stage disease and marks angiogenic microvessels. Clin Proteomics (2011) 0.89
Assessment of acute antivascular effects of vandetanib with high-resolution dynamic contrast-enhanced computed tomographic imaging in a human colon tumor xenograft model in the nude rat. Neoplasia (2010) 0.89
Role of bone marrow-derived cells in angiogenesis: focus on macrophages and pericytes. Cancer Microenviron (2012) 0.88
Nestin(+) tissue-resident multipotent stem cells contribute to tumor progression by differentiating into pericytes and smooth muscle cells resulting in blood vessel remodeling. Front Oncol (2014) 0.88
Molecule action mechanisms of NM-3 on human gastric cancer SGC-7901 cells in vivo or in vitro. World J Gastroenterol (2003) 0.87
Pathophysiology of tumor neovascularization. Vasc Health Risk Manag (2005) 0.86
Combined effects of pericytes in the tumor microenvironment. Stem Cells Int (2015) 0.85
Blood vessel maturation in human uveal melanoma: spatial distribution of neovessels and mature vasculature. Ophthalmic Res (2009) 0.85
Use of labeled tomato lectin for imaging vasculature structures. Histochem Cell Biol (2014) 0.85
Focal, periocular delivery of 2-deoxy-D-glucose as adjuvant to chemotherapy for treatment of advanced retinoblastoma. Invest Ophthalmol Vis Sci (2010) 0.84
Early quantification of the therapeutic efficacy of the vascular disrupting agent, CKD-516, using dynamic contrast-enhanced ultrasonography in rabbit VX2 liver tumors. Ultrasonography (2013) 0.83
Distinct roles of DKK1 and DKK2 in tumor angiogenesis. Angiogenesis (2013) 0.82
Pericytes on the tumor vasculature: jekyll or hyde? Cancer Microenviron (2012) 0.80
Platelet-derived growth factor receptor-beta, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma. BMC Cancer (2007) 0.80
Assessement of angiogenesis reveals blood vessel heterogeneity in lung carcinoma. Oncol Lett (2012) 0.79
A 3-D model of tumor progression based on complex automata driven by particle dynamics. J Mol Model (2009) 0.79
Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves the antiangiogenic efficacy for advanced stage mouse corneal neovascularization. Graefes Arch Clin Exp Ophthalmol (2011) 0.79
Retinoblastoma treatment: utilization of the glycolytic inhibitor, 2-deoxy-2-fluoro-D-glucose (2-FG), to target the chemoresistant hypoxic regions in LH(BETA)T(AG) retinal tumors. Invest Ophthalmol Vis Sci (2012) 0.78
Mechanisms controlling the effects of bevacizumab (avastin) on the inhibition of early but not late formed corneal neovascularization. PLoS One (2014) 0.78
Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy. Mol Cancer Res (2009) 0.78
Safety and efficacy of the multitargeted receptor kinase inhibitor pazopanib in the treatment of corneal neovascularization. Invest Ophthalmol Vis Sci (2013) 0.78
Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature within the Process of Vascular Remodeling: Cellular Basis, Clinical Relevance, and Implications for Stem Cell Therapy. Stem Cells Int (2016) 0.77
Targeting mast cells in gastric cancer with special reference to bone metastases. World J Gastroenterol (2015) 0.77
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science (1997) 10.54
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med (1995) 7.88
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature (1997) 7.66
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest (1999) 6.32
Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol (2000) 5.94
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development (1998) 5.91
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol (2002) 5.04
Effect of p53 status on tumor response to antiangiogenic therapy. Science (2002) 4.41
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Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res (1975) 3.59
Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. Cancer Res (2000) 3.14
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res (1997) 2.96
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J Exp Med (1995) 2.68
Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches. Cancer Metastasis Rev (2001) 2.16
The growth of the blood supply to melanoma transplants in the hamster cheek pouch. Lab Invest (1966) 1.94
Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents. Bioessays (1991) 1.93
Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J (2001) 1.86
Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Cancer Res (2001) 1.80
Role of the pericyte in wound healing. An ultrastructural study. Exp Mol Pathol (1970) 1.78
Blood vessel maturation: vascular development comes of age. J Clin Invest (1999) 1.70
Speculations on the role of ultraviolet radiation in the development of malignant melanoma. J Natl Cancer Inst (1979) 1.59
Differentiation of vascular endothelium in the chick chorioallantois: a structural and autoradiographic study. Dev Biol (1974) 1.42
Heterogeneous vascular dependence of tumor cell populations. Am J Pathol (2001) 1.31
Stabilization of breast cancer xenograft tumour neovasculature by angiopoietin-1. Br J Cancer (2002) 1.12
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Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations. Cancer Res (2001) 1.04
Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12. Cancer Res (1999) 0.96
Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res (2002) 0.91
Angiogenesis and angiogenesis inhibitors in cancer. Forum (Genova) (1999) 0.86
Angiogenesis research: from laboratory to clinic. Forum (Genova) (2000) 0.85
Computerized image-based detection and grading of lymphocytic infiltration in HER2+ breast cancer histopathology. IEEE Trans Biomed Eng (2009) 2.56
Molecular-cytogenetic analysis of HER-2/neu gene in BRCA1-associated breast cancers. Cancer Res (2002) 2.25
Automated detection of prostatic adenocarcinoma from high-resolution ex vivo MRI. IEEE Trans Med Imaging (2005) 2.08
Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res (2002) 2.05
High-throughput detection of prostate cancer in histological sections using probabilistic pairwise Markov models. Med Image Anal (2010) 2.04
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest (2010) 2.00
Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle. J Appl Physiol (1985) (2006) 1.99
Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy. Ann Thorac Surg (2006) 1.82
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res (2004) 1.81
Activated STAT3 is a mediator and biomarker of VEGF endothelial activation. Cancer Biol Ther (2008) 1.77
APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions. Cell Host Microbe (2010) 1.67
Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY43-9006). Am J Pathol (2006) 1.66
Validation and toxicity of PI3K/Akt pathway inhibition by HIV protease inhibitors in humans. Cancer Biol Ther (2008) 1.65
Cascaded discrimination of normal, abnormal, and confounder classes in histopathology: Gleason grading of prostate cancer. BMC Bioinformatics (2012) 1.42
High throughput analysis of breast cancer specimens on the grid. Med Image Comput Comput Assist Interv (2007) 1.40
Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. PLoS One (2009) 1.37
Determining histology-MRI slice correspondences for defining MRI-based disease signatures of prostate cancer. Comput Med Imaging Graph (2011) 1.28
Oxygen distribution in murine tumors: characterization using oxygen-dependent quenching of phosphorescence. J Appl Physiol (1985) (2004) 1.22
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest (2015) 1.17
Downregulation of Rap1GAP contributes to Ras transformation. Mol Cell Biol (2007) 1.16
Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis. Biochem Pharmacol (2007) 1.14
Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues. Cancer Biol Ther (2009) 1.14
Telomerase-specific T-cell immunity in breast cancer: effect of vaccination on tumor immunosurveillance. Cancer Res (2007) 1.08
Supervised multi-view canonical correlation analysis (sMVCCA): integrating histologic and proteomic features for predicting recurrent prostate cancer. IEEE Trans Med Imaging (2014) 1.07
Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies. Opt Express (2007) 1.05
Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol Cell Biol (2010) 1.03
Graph embedding to improve supervised classification and novel class detection: application to prostate cancer. Med Image Comput Comput Assist Interv (2005) 1.03
Ionizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis. Cancer Biol Ther (2005) 1.03
The antivascular action of physiotherapy ultrasound on murine tumors. Ultrasound Med Biol (2005) 1.02
Effect of VEGF and VEGF Trap on vascular endothelial cell signaling in tumors. Cancer Biol Ther (2010) 1.02
Loss of Rap1GAP in papillary thyroid cancer. J Clin Endocrinol Metab (2008) 1.02
Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus. Cancer Res (2003) 1.00
Fibrillin and other matrix proteins in mitral valve prolapse syndrome. Ann Thorac Surg (2004) 0.97
Fungal rhinosinusitis: a retrospective microbiologic and pathologic review of 400 patients at a single university medical center. Int J Otolaryngol (2012) 0.96
Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis (2010) 0.94
Signaling pathways in NSCLC as a predictor of outcome and response to therapy. Lung (2004) 0.93
Supervised regularized canonical correlation analysis: integrating histologic and proteomic measurements for predicting biochemical recurrence following prostate surgery. BMC Bioinformatics (2011) 0.93
Ectopic functioning adrenocortical oncocytic adenoma (oncocytoma) with myelolipoma causing virilization. Case Rep Pathol (2012) 0.92
Spatially weighted mutual information (SWMI) for registration of digitally reconstructed ex vivo whole mount histology and in vivo prostate MRI. Conf Proc IEEE Eng Med Biol Soc (2011) 0.91
Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res (2002) 0.91
Dose-dependent effects of topical tobramycin in an animal model of Pseudomonas sinusitis. Am J Rhinol (2007) 0.90
Radiographic and histologic analysis of the bone underlying inverted papillomas. Laryngoscope (2006) 0.90
Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Anal Cell Pathol (Amst) (2012) 0.89
High-throughput biomarker segmentation on ovarian cancer tissue microarrays via hierarchical normalized cuts. IEEE Trans Biomed Eng (2011) 0.89
Computer aided automatic detection of malignant lesions in diffuse optical mammography. Med Phys (2010) 0.88
Variability in the diagnosis of dysplasia in ulcerative colitis by dynamic telepathology. Oncol Rep (2006) 0.86
Cell-based quantification of molecular biomarkers in histopathology specimens. Histopathology (2011) 0.86
Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy. Biomed Opt Express (2012) 0.85
Image microarrays (IMA): Digital pathology's missing tool. J Pathol Inform (2011) 0.84
Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition. Cancer Res (2003) 0.84
Ras-related protein 1 and the insulin-like growth factor type I receptor are associated with risk of progression in patients diagnosed with carcinoma in situ. Breast Cancer Res Treat (2010) 0.84
Multigated contrast-enhanced power Doppler to measure blood flow in mice tumors. Ultrasound Med Biol (2003) 0.84
Hierarchical normalized cuts: unsupervised segmentation of vascular biomarkers from ovarian cancer tissue microarrays. Med Image Comput Comput Assist Interv (2009) 0.84
The impact of HER-2 status on local recurrence in women with stage I-II breast cancer treated with breast-conserving therapy. Breast J (2006) 0.84
In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in formalin-fixed, paraffin-embedded pulmonary specimens using a locked nucleic acid probe: a rapid means for identification in tissue sections. Diagn Mol Pathol (2010) 0.84
Eccrine porocarcinoma of the nose: case report and review of world literature. Arch Otolaryngol Head Neck Surg (2006) 0.83
Oxygen pressures in the interstitial space of skeletal muscle and tumors in vivo. Adv Exp Med Biol (2008) 0.82
Tissue-based immune monitoring II: multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Cancer Biol Ther (2011) 0.82
Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant model. Endocrinology (2012) 0.81
In situ detection of aspergillus 18s ribosomal RNA Sequences using a terminally biotinylated locked nucleic acid (LNA) probe. Diagn Mol Pathol (2009) 0.81
Toxicity study of gemcitabine, oxaliplatin, and bevacizumab, followed by 5-fluorouracil, oxaliplatin, bevacizumab, and radiotherapy, in patients with locally advanced pancreatic cancer. Cancer Chemother Pharmacol (2013) 0.80
Bone morphogenetic proteins are expressed by both bone-forming and non-bone-forming lesions. Arch Pathol Lab Med (2004) 0.80
In situ hybridization for specific fungal organisms in acute invasive fungal rhinosinusitis. Am J Clin Pathol (2011) 0.79
Dose-response relationship of ultrasound contrast agent in an in vivo murine melanoma model. Cancer Imaging (2007) 0.78
Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy. Mol Cancer Res (2009) 0.78
Rapid In-situ hybridization for dematiaceous fungi using a broad-spectrum oligonucleotide DNA probe. Diagn Mol Pathol (2011) 0.77
Measuring oxygen in living tissue: intravascular, interstitial, and "tissue" oxygen measurements. Adv Exp Med Biol (2011) 0.76
Embryonal and alveolar rhabdomyosarcoma of parameningeal sites in adults: a report of 13 cases. Int J Surg Pathol (2008) 0.76
Supervised regularized canonical correlation analysis: integrating histologic and proteomic data for predicting biochemical failures. Conf Proc IEEE Eng Med Biol Soc (2011) 0.76
Editorial Commentary: "All That Glitters Is Not Gold". Arthroscopy (2016) 0.75
Editorial Commentary: Does Early Arthroscopy of Subtle Instability in High Ankle Sprains Hasten Return to Play in Elite Athletes? Arthroscopy (2016) 0.75
Editorial Commentary: Planting a Tree to Create the Shade-Performing Quality Long-term Studies Requires Forethought. Arthroscopy (2016) 0.75
Editorial Commentary: To Screw or to Sew-Which Is Better for Arthroscopic Biceps Tenodesis? Arthroscopy (2016) 0.75
Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions. Arch Pathol Lab Med (2004) 0.75
Modeling antiangiogenesis gene therapy. Cancer Biol Ther (2002) 0.75
Sinonasal undifferentiated carcinoma as a third primary neoplasm: A case report and review of the literature. Ear Nose Throat J (2015) 0.75
Editorial Commentary: Can It Really Be That Simple? Predicting Risk Factors for Failed Arthroscopic Rotator Cuff Repair. Arthroscopy (2016) 0.75
The role of tumor oxygenation in vascular and clinical response to angiogenesis inhibition. Adv Exp Med Biol (2003) 0.75
Editorial Commentary: Pitching a New Curve: Identifying the Etiology of Nontraumatic Throwing Injuries. Arthroscopy (2017) 0.75
Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study). Am J Surg Pathol (2017) 0.75