Published in Prog Neurobiol on December 01, 2002
Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: focus on cognition. Biochem Pharmacol (2007) 1.46
The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer. Prog Neurobiol (2010) 1.09
Shared long-range regulatory elements coordinate expression of a gene cluster encoding nicotinic receptor heteromeric subtypes. Mol Cell Biol (2006) 1.01
Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes. Eur J Neurosci (2010) 0.96
Selective deletion of the alpha5 subunit differentially affects somatic-dendritic versus axonally targeted nicotinic ACh receptors in mouse. J Physiol (2004) 0.94
Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain. Biochem Pharmacol (2009) 0.91
Efficacy and safety of the novel α₄β₂ neuronal nicotinic receptor partial agonist ABT-089 in adults with attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled crossover study. Psychopharmacology (Berl) (2011) 0.91
Use of an α3β4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties. Neuropharmacology (2012) 0.89
Safety and efficacy of ABT-089 in pediatric attention-deficit/hyperactivity disorder: results from two randomized placebo-controlled clinical trials. J Am Acad Child Adolesc Psychiatry (2010) 0.89
Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. Neuroscience (2010) 0.82
CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation. Br J Pharmacol (2013) 0.81
Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation. Mol Ther (2017) 0.79
Functional expression of human α9* nicotinic acetylcholine receptors in X. laevis oocytes is dependent on the α9 subunit 5' UTR. PLoS One (2013) 0.78
Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. J Biol Chem (2014) 0.78
N-cadherin induces partial differentiation of cholinergic presynaptic terminals in heterologous cultures of brainstem neurons and CHO cells. Front Synaptic Neurosci (2012) 0.77
The Effects of Nerve Growth Factor on Nicotinic Synaptic Transmission in Mouse Airway Parasympathetic Neurons. Am J Respir Cell Mol Biol (2015) 0.75
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
The p.L302P mutation in the lysosomal enzyme gene SMPD1 is a risk factor for Parkinson disease. Neurology (2013) 2.64
A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome. Am J Hum Genet (2008) 2.58
Carrier screening for Gaucher disease: lessons for low-penetrance, treatable diseases. JAMA (2007) 2.51
A novel founder mutation in the RNASEL gene, 471delAAAG, is associated with prostate cancer in Ashkenazi Jews. Am J Hum Genet (2002) 2.24
Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations. Mov Disord (2013) 2.01
The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo. Mol Pharmacol (2003) 2.00
Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A (2006) 1.99
X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment. Nat Genet (2008) 1.95
Epilepsy and mental retardation limited to females: an under-recognized disorder. Brain (2008) 1.94
PRRT2 mutations cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndrome. Am J Hum Genet (2012) 1.91
Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community. Hum Mol Genet (2003) 1.65
Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol (2009) 1.53
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
Array-based comparative genome hybridization in clinical genetics. Pediatr Res (2006) 1.49
False-positive results using a Gaucher diagnostic kit--RecTL and N370S. Mol Genet Metab (2010) 1.48
Retinal thickness in patients with mild cognitive impairment and Alzheimer's disease. Clin Neurol Neurosurg (2011) 1.42
Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1. Brain (2008) 1.41
Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft. Cancer Res (2002) 1.40
Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium. J Cell Biol (2002) 1.33
Gait alterations in healthy carriers of the LRRK2 G2019S mutation. Ann Neurol (2011) 1.29
Computer-based, personalized cognitive training versus classical computer games: a randomized double-blind prospective trial of cognitive stimulation. Neuroepidemiology (2011) 1.26
Rotigotine transdermal patch in early Parkinson's disease: a randomized, double-blind, controlled study versus placebo and ropinirole. Mov Disord (2007) 1.26
Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. Physiol Genomics (2004) 1.17
Development of dyskinesias in a 5-year trial of ropinirole and L-dopa. Mov Disord (2006) 1.13
Ten-year follow-up of Parkinson's disease patients randomized to initial therapy with ropinirole or levodopa. Mov Disord (2007) 1.11
White matter changes in multiple sclerosis: correlation of q-space diffusion MRI and 1H MRS. Magn Reson Imaging (2005) 1.09
Decreased first trimester PAPP-A is a predictor of adverse pregnancy outcome. Prenat Diagn (2002) 1.08
Association of sequence alterations in the putative promoter of RAB7L1 with a reduced parkinson disease risk. Arch Neurol (2012) 1.05
Molecular analysis of the APC gene in 71 Israeli families: 17 novel mutations. Hum Mutat (2002) 1.03
Autonomic function in mice lacking alpha5 neuronal nicotinic acetylcholine receptor subunit. J Physiol (2002) 1.03
Autonomic impairment in amyotrophic lateral sclerosis. Curr Opin Neurol (2005) 1.00
Rett syndrome: clinical manifestations in males with MECP2 mutations. J Child Neurol (2002) 1.00
Genetic testing in Israel: an overview. Annu Rev Genomics Hum Genet (2009) 0.99
Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families. Epilepsia (2004) 0.98
Use of the virtual action planning supermarket for the diagnosis of mild cognitive impairment: a preliminary study. Dement Geriatr Cogn Disord (2009) 0.98
Sexual dysfunction in Parkinson's disease. J Sex Marital Ther (2004) 0.98
Central role of fibroblast alpha3 nicotinic acetylcholine receptor in mediating cutaneous effects of nicotine. Lab Invest (2003) 0.98
Smoking and tea consumption delay onset of Parkinson's disease. Parkinsonism Relat Disord (2008) 0.97
Phosphatidylserine containing omega-3 fatty acids may improve memory abilities in non-demented elderly with memory complaints: a double-blind placebo-controlled trial. Dement Geriatr Cogn Disord (2010) 0.97
Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors. Neoplasia (2006) 0.97
Tau and 14-3-3 of genetic and sporadic Creutzfeldt-Jakob disease patients in Israel. J Neurol (2010) 0.96
Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes. Eur J Neurosci (2010) 0.96
FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes. Genes Chromosomes Cancer (2007) 0.95
Selective deletion of the alpha5 subunit differentially affects somatic-dendritic versus axonally targeted nicotinic ACh receptors in mouse. J Physiol (2004) 0.94
Screening for familial dysautonomia in Israel: evidence for higher carrier rate among Polish Ashkenazi Jews. Genet Test (2003) 0.94
Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial. Int J Geriatr Psychiatry (2010) 0.94
Large-scale population screening for spinal muscular atrophy: clinical implications. Genet Med (2011) 0.94
Lower core body temperature and attenuated nicotine-induced hypothermic response in mice lacking the beta4 neuronal nicotinic acetylcholine receptor subunit. Brain Res Bull (2005) 0.94
Broad phenotypic heterogeneity due to a novel SCN1A mutation in a family with genetic epilepsy with febrile seizures plus. J Child Neurol (2013) 0.93
The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews. J Neural Transm (Vienna) (2009) 0.93
Thalamo-striatal diffusion reductions precede disease onset in prion mutation carriers. Brain (2009) 0.93
TBC1D24 mutation associated with focal epilepsy, cognitive impairment and a distinctive cerebro-cerebellar malformation. Epilepsy Res (2013) 0.92
Homocysteine, stroke, and dementia. Stroke (2002) 0.91
Functional analysis of the Aurora Kinase A Ile31 allelic variant in human prostate. Neoplasia (2007) 0.91
Maternal serum HCG is higher in the presence of a female fetus as early as week 3 post-fertilization. Hum Reprod (2002) 0.91
Variable clinical presentation of an MUC1 mutation causing medullary cystic kidney disease type 1. Clin J Am Soc Nephrol (2014) 0.90
Lower cognitive performance in healthy G2019S LRRK2 mutation carriers. Neurology (2012) 0.90
Fighting the risk of developing Parkinson's disease; clinical counseling for first degree relatives of patients with Parkinson's disease. J Neurol Sci (2011) 0.89
Cerebral pathological and compensatory mechanisms in the premotor phase of leucine-rich repeat kinase 2 parkinsonism. Brain (2012) 0.89
Mild cognitive impairment: conceptual, assessment, ethical, and social issues. Clin Interv Aging (2008) 0.88
Changes in axonal morphology in experimental autoimmune neuritis as studied by high b-value q-space (1)H and (2)H DQF diffusion magnetic resonance spectroscopy. Magn Reson Med (2002) 0.88
Human-computer interaction in the administration and analysis of neuropsychological tests. Comput Methods Programs Biomed (2004) 0.88
The age at motor symptoms onset in LRRK2-associated Parkinson's disease is affected by a variation in the MAPT locus: a possible interaction. J Mol Neurosci (2011) 0.87
Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes. Exp Cell Res (2004) 0.87
Fall risk and gait in Parkinson's disease: the role of the LRRK2 G2019S mutation. Mov Disord (2013) 0.87
Autonomic impairment in a transgenic mouse model of amyotrophic lateral sclerosis. Auton Neurosci (2011) 0.87
The effect of cigarette smoking, tea, and coffee consumption on the progression of Parkinson's disease. Parkinsonism Relat Disord (2007) 0.87
Interspecies comparison of prostate cancer gene-expression profiles reveals genes associated with aggressive tumors. Prostate (2009) 0.87
Early onset dementia: clinical and social aspects. Int Psychogeriatr (2009) 0.87
Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans. Hum Mol Genet (2010) 0.87
Two novel translocations, t(2;4)(q35;q31) and t(X;12)(q22;q24), as the only karyotypic abnormalities in a malignant peripheral nerve sheath tumor of the skull base. Cancer Genet Cytogenet (2003) 0.87
Antiphospholipid syndrome induction exacerbates a transgenic Alzheimer disease model on a female background. Neurobiol Aging (2009) 0.86
Analysis of genetic polymorphisms in acetylcholinesterase as reflected in different populations. Curr Alzheimer Res (2005) 0.86
Predictors for poststroke outcomes: the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study protocol. Int J Stroke (2011) 0.86
Subunit composition of α5-containing nicotinic receptors in the rodent habenula. J Neurochem (2012) 0.86
A new clinical and molecular form of Unverricht-Lundborg disease localized by homozygosity mapping. Brain (2005) 0.85
Gender effect on time to levodopa-induced dyskinesias. J Neurol (2011) 0.85
Mutation screening and association study of the candidate prostate cancer susceptibility genes MSR1, PTEN, and KLF6. Prostate (2006) 0.85
Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis. Life Sci (2003) 0.85
Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor. Neuroreport (2002) 0.85
Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers. Cortex (2013) 0.85
Computerized diagnosis of mild cognitive impairment. Alzheimers Dement (2007) 0.84
Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutation. Parkinsonism Relat Disord (2012) 0.84
Gender differences in lay persons' beliefs and knowledge about Alzheimer's disease (AD): a national representative study of Israeli adults. Arch Gerontol Geriatr (2012) 0.84
Consensus statement for diagnosis of subcortical small vessel disease. J Cereb Blood Flow Metab (2016) 0.84
Prevalence and clinical features of dementia associated with the antiphospholipid syndrome and circulating anticoagulants. J Neurol Sci (2002) 0.83
MECP2 mutations in Israel: implications for molecular analysis, genetic counseling, and prenatal diagnosis in Rett syndrome. Hum Mutat (2002) 0.83
Occurrence of fatigue over 20 years after recovery from Guillain-Barré syndrome. J Neurol Sci (2012) 0.83
Neuropsychological evaluation of late-onset post-radiotherapy encephalopathy: a comparison with vascular dementia. J Neurol Sci (2004) 0.83
Ashkenazi Parkinson's disease patients with the LRRK2 G2019S mutation share a common founder dating from the second to fifth centuries. Neurogenetics (2009) 0.83
Deficiency of nicotinic acetylcholine receptor beta 4 subunit causes autonomic cardiac and intestinal dysfunction. Mol Pharmacol (2003) 0.83
Increased thrombin inhibition in experimental autoimmune encephalomyelitis. J Neurosci Res (2005) 0.83
HIF1A C1772T polymorphism leads to HIF-1α mRNA overexpression in prostate cancer patients. Cancer Biol Ther (2012) 0.83
Sperm epidermal growth factor receptor (EGFR) mediates α7 acetylcholine receptor (AChR) activation to promote fertilization. J Biol Chem (2012) 0.83
Differential brain transcriptome of beta4 nAChR subunit-deficient mice: is it the effect of the null mutation or the background strain? Physiol Genomics (2006) 0.83
Cerebral vasomotor reactivity in Parkinson's disease, multiple system atrophy and pure autonomic failure. J Neurol Sci (2006) 0.82
Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome. Immunobiology (2003) 0.82