Published in Eur J Clin Invest on December 01, 2002
A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation. Cell (2009) 2.61
All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase. FEBS J (2015) 0.93
Palmitate action to inhibit glycogen synthase and stimulate protein phosphatase 2A increases with risk factors for type 2 diabetes. Am J Physiol Endocrinol Metab (2007) 0.87
Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males. J Appl Physiol (1985) (2012) 0.83
Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching. Am J Physiol Endocrinol Metab (2013) 0.82
High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit. Endocrinology (2013) 0.80
Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d. J Biol Chem (2015) 0.76
Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia. Physiol Rep (2014) 0.75
Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study. Diabetologia (1999) 3.64
Randomised controlled trial of structured personal care of type 2 diabetes mellitus. BMJ (2001) 3.12
How do waiting times affect radiation dose fractionation schedules? Australas Radiol (2000) 2.59
The epidemic of type 2 diabetes is a statistical artefact. Diabetologia (2005) 2.41
Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia (1997) 2.41
Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins. BMJ (1995) 2.40
Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus. J Clin Invest (1992) 1.96
Genetic versus environmental aetiology of the metabolic syndrome among male and female twins. Diabetologia (2001) 1.65
Impaired beta cell glucose sensitivity rather than inadequate compensation for insulin resistance is the dominant defect in glucose intolerance. Diabetologia (2010) 1.64
Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training. Diabetologia (2010) 1.57
Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism. J Clin Invest (1987) 1.56
Insulin action and age. European Group for the Study of Insulin Resistance (EGIR). Diabetes (1996) 1.52
City air pollution of polycyclic aromatic hydrocarbons and other mutagens: occurrence, sources and health effects. Sci Total Environ (1996) 1.52
The new Danish Twin Register: establishment and analysis of twinning rates. Int J Epidemiol (1995) 1.50
Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia (1991) 1.49
Clinical impact of mild carbohydrate intolerance in pregnancy: a study of 2904 nondiabetic Danish women with risk factors for gestational diabetes mellitus. Am J Obstet Gynecol (2001) 1.47
Does zygosity influence the metabolic profile of twins? A population based cross sectional study. BMJ (1999) 1.46
[Salmeterol improves control in asthmatic patients treated in general practice. A comparative study of salmeterol (Serevent) and salbutamol (Ventoline) in patients with mild to moderate asthma]. Ugeskr Laeger (1995) 1.41
GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease? Diabetes (2001) 1.38
Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance. J Clin Endocrinol Metab (1999) 1.37
Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus. J Clin Invest (1991) 1.36
Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes. Diabetologia (2001) 1.34
Triglyceride-induced diabetes associated with familial lipoprotein lipase deficiency. Diabetes (1999) 1.31
Expression of insulin regulatable glucose transporters in skeletal muscle from type 2 (non-insulin-dependent) diabetic patients. Diabetologia (1990) 1.30
On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion. Diabetologia (1990) 1.26
Are men testing? Sex differentials in HIV testing in Mpumalanga Province, South Africa. AIDS Care (2010) 1.25
Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects. Am J Clin Nutr (1980) 1.24
Lumbar vertebral body compressive strength evaluated by dual-energy X-ray absorptiometry, quantitative computed tomography, and ashing. Bone (1999) 1.22
Decreased activation of skeletal muscle glycogen synthase by mixed-meal ingestion in NIDDM. Diabetes (1988) 1.21
Age-dependent impact of zygosity and birth weight on insulin secretion and insulin action in twins. Diabetologia (2002) 1.19
Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients. Troglitazone Study Group. Diabetologia (1996) 1.17
Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus. J Clin Invest (1995) 1.17
A cellular model system of differentiated human myotubes. APMIS (2001) 1.15
Genetic diversity and population structure of 20 North European cattle breeds. J Hered (2001) 1.15
Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels. J Clin Endocrinol Metab (2005) 1.14
Classification of newly diagnosed diabetic patients as insulin-requiring or non-insulin-requiring based on clinical and biochemical variables. Diabetes Care (1989) 1.13
Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: the RISC Study. Diabetologia (2011) 1.13
Assessment of the safety of foods derived from genetically modified (GM) crops. Food Chem Toxicol (2004) 1.11
No association between birth weight and Type 1 diabetes mellitus--a twin-control study. Diabet Med (2000) 1.11
Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes. Diabetologia (2010) 1.11
Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans. Chirality (1997) 1.10
Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol. Diabetologia (2005) 1.09
Rosiglitazone RECORD study: glucose control outcomes at 18 months. Diabet Med (2007) 1.08
Clinical symptoms according to genotype amongst patients with hereditary haemorrhagic telangiectasia. J Intern Med (2005) 1.08
Do acute mucosal reactions lead to consequential late reactions in patients with head and neck cancer? Radiother Oncol (1999) 1.08
Maternal and perinatal outcomes in 143 Danish women with gestational diabetes mellitus and 143 controls with a similar risk profile. Diabet Med (2000) 1.08
Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population. J Intern Med (2011) 1.07
Changes in patient weight and the impact of antidiabetic therapy during the first 5 years after diagnosis of diabetes mellitus. Diabetologia (2006) 1.06
The pathogenic role of an insulin-receptor defect in diabetes mellitus of the obese. Diabetes (1978) 1.05
Effects of insulin on kidney function and sodium excretion in healthy subjects. Diabetologia (1989) 1.05
Insulin receptor binding and receptor-mediated insulin degradation in human adipocytes. Diabetologia (1981) 1.04
Phase II multicenter study of brief single-agent methotrexate followed by irradiation in primary CNS lymphoma. J Clin Oncol (2000) 1.04
Correlations between insulin sensitivity and bone mineral density in non-diabetic men. Diabet Med (2000) 1.03
Assessment of hepatic insulin action in obese type 2 diabetic patients. Diabetes (2001) 1.03
A reduced number of insulin receptors in patients with Prader-Willi syndrome. Acta Endocrinol (Copenh) (1983) 1.03
Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique. Metabolism (1996) 1.03
Prevalence and mortality of acute myocardial infarction in patients with diabetes. Diabetes Care (1985) 1.03
No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910-1989. Diabetologia (2011) 1.02
Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women: a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res (2003) 1.02
Increased insulin receptors after exercise in patients with insulin-dependent diabetes mellitus. N Engl J Med (1980) 1.01
Insulin analogues and severe hypoglycaemia in type 1 diabetes. Diabetes Res Clin Pract (2011) 1.01
Direct evidence of fiber type-dependent GLUT-4 expression in human skeletal muscle. Am J Physiol Endocrinol Metab (2000) 1.01
Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes. Diabetologia (2008) 1.00
Multiple defects of both hepatic and peripheral intracellular glucose processing contribute to the hyperglycaemia of NIDDM. Diabetologia (1995) 1.00
Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women - results of the Danish Osteoporosis Prevention Study. Maturitas (2000) 1.00
Measurement of fractional whole-body gluconeogenesis in humans from blood samples using 2H nuclear magnetic resonance spectroscopy. Diabetes (2003) 0.99
Improved in vivo insulin effect during continuous subcutaneous insulin infusion in patients with IDDM. Diabetes (1984) 0.99
Decreased binding of insulin to its receptor in patients with congenital generalized lipodystrophy. N Engl J Med (1977) 0.98
Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle. Diabetologia (2009) 0.98
Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia (1992) 0.97
Increased glucose effectiveness in normoglycemic but insulin-resistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism. J Clin Invest (1994) 0.97
Age- and gender-related differences in vertebral bone mass, density, and strength. J Bone Miner Res (1999) 0.97
The antiviral 2',5'-oligoadenylate synthetase is persistently activated in type 1 diabetes. Clin Immunol (2000) 0.96
Variation in absorption of NPH insulin due to intramuscular injection. Diabetes Care (1990) 0.96
Proliferation conditions for human satellite cells. The fractional content of satellite cells. APMIS (2001) 0.96
Altered basal and insulin-stimulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects. Diabetologia (1996) 0.96
National mutation study among Danish patients with hereditary haemorrhagic telangiectasia. Clin Genet (2013) 0.95
Intramuscular versus subcutaneous injection of unmodified insulin: consequences for blood glucose control in patients with type 1 diabetes mellitus. Diabet Med (1990) 0.95
Cytokines and T-lymphocyte subsets in healthy post-menopausal women: estrogen retards bone loss without affecting the release of IL-1 or IL-1ra. Bone (1997) 0.94
Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects. Diabetologia (1978) 0.94
Weight history of patients with newly diagnosed Type 2 diabetes. Diabet Med (2008) 0.93
Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes. Diabetologia (2006) 0.92
The spectrum of ABCC8 mutations in Norwegian patients with congenital hyperinsulinism of infancy. Clin Genet (2009) 0.92
Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes. Eur J Clin Invest (2005) 0.92
Insulin resistance in growth hormone-deficient adults: defects in glucose utilization and glycogen synthase activity. J Clin Endocrinol Metab (1996) 0.92
Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period. J Clin Endocrinol Metab (1994) 0.91
Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide. Acta Endocrinol (Copenh) (1979) 0.91
Cytokines and bone loss in a 5-year longitudinal study--hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin-1-receptor antagonist: the Danish Osteoporosis Prevention Study. J Bone Miner Res (2000) 0.91
Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study. Br J Clin Pharmacol (1990) 0.90
Structured personal care of type 2 diabetes: a 19 year follow-up of the study Diabetes Care in General Practice (DCGP). Diabetologia (2013) 0.90
Glucose transporter expression in human skeletal muscle fibers. Am J Physiol Endocrinol Metab (2000) 0.89
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins. Diabetologia (2012) 0.89
Risk and mechanism of dexamethasone-induced deterioration of glucose tolerance in non-diabetic first-degree relatives of NIDDM patients. Diabetologia (1997) 0.89
Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity. Int J Obes (1983) 0.89