Published in Cytokine on November 24, 2002
Aminoacyl tRNA synthetases and their connections to disease. Proc Natl Acad Sci U S A (2008) 2.41
Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc Natl Acad Sci U S A (2005) 1.55
Aminoacyl-tRNA synthetase complexes: molecular multitasking revealed. FEMS Microbiol Rev (2008) 1.17
The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair. Am J Pathol (2005) 1.16
Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation. Proc Natl Acad Sci U S A (2008) 1.11
Hormonal activity of AIMP1/p43 for glucose homeostasis. Proc Natl Acad Sci U S A (2006) 1.08
Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases. Am J Pathol (2007) 0.93
Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle. Respir Res (2010) 0.87
Resveratrol at high doses acts as an apoptotic inducer in endothelial cells. Cancer Res Treat (2006) 0.84
Role of tumour necrosis factor-alpha and other cytokines in ischemia-reperfusion-induced injury in the heart. Exp Clin Cardiol (2005) 0.83
ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt. Stem Cells Dev (2013) 0.75
MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res (2008) 5.54
Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. Cell (2012) 3.38
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. Cell (2004) 3.12
Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers. Trends Biochem Sci (2005) 2.60
Aminoacyl tRNA synthetases and their connections to disease. Proc Natl Acad Sci U S A (2008) 2.41
Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PLoS One (2011) 2.29
Metabolic tumor volume of [18F]-fluorodeoxyglucose positron emission tomography/computed tomography predicts short-term outcome to radiotherapy with or without chemotherapy in pharyngeal cancer. Clin Cancer Res (2009) 2.12
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. J Neurosci (2005) 2.06
Staging laparoscopy for the management of early-stage ovarian cancer: a metaanalysis. Am J Obstet Gynecol (2013) 2.04
Aminoacyl-tRNA synthetase complexes: beyond translation. J Cell Sci (2004) 1.98
Prevalence and mechanisms of low- and high-level mupirocin resistance in staphylococci isolated from a Korean hospital. J Antimicrob Chemother (2003) 1.69
The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR. Cell (2005) 1.64
The expressions of the Rb pathway in cervical intraepithelial neoplasia; predictive and prognostic significance. Gynecol Oncol (2006) 1.60
Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. Nat Genet (2003) 1.57
Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc Natl Acad Sci U S A (2005) 1.55
Transumbilical single-port access versus conventional total laparoscopic hysterectomy: surgical outcomes. Am J Obstet Gynecol (2010) 1.52
Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ. Cell Rep (2013) 1.44
AIMP1 deficiency enhances airway hyperreactivity in mice via increased TH2 immune responses. Clin Immunol (2012) 1.43
p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance. Proc Natl Acad Sci U S A (2002) 1.42
Effects of uterine manipulation on surgical outcomes in laparoscopic management of endometrial cancer: a prospective randomized clinical trial. Int J Gynecol Cancer (2013) 1.40
Tumor heterogeneity of FIGO stage III carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys (2009) 1.39
A two-photon fluorescent probe for lipid raft imaging: C-laurdan. Chembiochem (2007) 1.36
Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1. Mol Cell Biol (2002) 1.35
LysRS serves as a key signaling molecule in the immune response by regulating gene expression. Mol Cell (2009) 1.35
Analysis of chromosomal changes in serous ovarian carcinoma using high-resolution array comparative genomic hybridization: Potential predictive markers of chemoresistant disease. Genes Chromosomes Cancer (2007) 1.34
A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase. Nat Struct Mol Biol (2004) 1.34
Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. Clin Chim Acta (2008) 1.27
Retrovirus-specific packaging of aminoacyl-tRNA synthetases with cognate primer tRNAs. J Virol (2002) 1.27
Aminoacyl-tRNA synthetase-interacting multifunctional proteins (AIMPs): a triad for cellular homeostasis. IUBMB Life (2010) 1.26
Lipid raft proteome reveals ATP synthase complex in the cell surface. Proteomics (2004) 1.25
A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation. Genes Dev (2009) 1.25
AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53. Proc Natl Acad Sci U S A (2008) 1.23
Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis. Proc Natl Acad Sci U S A (2012) 1.21
Structural switch of lysyl-tRNA synthetase between translation and transcription. Mol Cell (2012) 1.17
The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair. Am J Pathol (2005) 1.16
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling. Nat Commun (2013) 1.16
Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. Nat Chem Biol (2012) 1.15
Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis. J Biol Chem (2002) 1.14
Agonist recognition sites in the cytosolic tails of vanilloid receptor 1. J Biol Chem (2002) 1.14
Cellular distribution of Lysyl-tRNA synthetase and its interaction with Gag during human immunodeficiency virus type 1 assembly. J Virol (2004) 1.12
Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis. PLoS Genet (2011) 1.12
Cathepsin D and eukaryotic translation elongation factor 1 as promising markers of cellular senescence. Cancer Res (2009) 1.11
Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer. J Mol Cell Biol (2012) 1.10
Discovery of novel indazole-linked triazoles as antifungal agents. Bioorg Med Chem Lett (2007) 1.08
Hormonal activity of AIMP1/p43 for glucose homeostasis. Proc Natl Acad Sci U S A (2006) 1.08
Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3. Proc Natl Acad Sci U S A (2011) 1.07
Amyloid beta oligomerization is induced by brain lipid rafts. J Cell Biochem (2006) 1.07
Monocyte cell adhesion induced by a human aminoacyl-tRNA synthetase-associated factor, p43: identification of the related adhesion molecules and signal pathways. J Leukoc Biol (2002) 1.07
Involvement of mitophagy in oncogenic K-Ras-induced transformation: overcoming a cellular energy deficit from glucose deficiency. Autophagy (2011) 1.06
Oxidation-reduction respiratory chains and ATP synthase complex are localized in detergent-resistant lipid rafts. Proteomics (2006) 1.06
Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches. Int J Oncol (2009) 1.04
The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes. Biochem Biophys Res Commun (2009) 1.03
Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug. BMC Syst Biol (2012) 1.03
Hierarchical network between the components of the multi-tRNA synthetase complex: implications for complex formation. J Biol Chem (2006) 1.02
The pivotal role of reactive oxygen species generation in the hypoxia-induced stimulation of adipose-derived stem cells. Stem Cells Dev (2011) 1.02
Expression of the p16 and Ki-67 in relation to the grade of cervical intraepithelial neoplasia and high-risk human papillomavirus infection. J Gynecol Oncol (2008) 1.02
CDA: combinatorial drug discovery using transcriptional response modules. PLoS One (2012) 1.01
Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells. Biochem Pharmacol (2012) 1.01
Molecular network and functional implications of macromolecular tRNA synthetase complex. Biochem Biophys Res Commun (2003) 1.01
Berberine inhibits human colon cancer cell migration via AMP-activated protein kinase-mediated downregulation of integrin β1 signaling. Biochem Biophys Res Commun (2012) 1.01
Primary involvement of NADPH oxidase 4 in hypoxia-induced generation of reactive oxygen species in adipose-derived stem cells. Stem Cells Dev (2012) 1.00
Identification of gp96 as a novel target for treatment of autoimmune disease in mice. PLoS One (2010) 1.00
Diagnosis and staging of primary ovarian cancer: correlation between PET/CT, Doppler US, and CT or MRI. Gynecol Oncol (2009) 1.00
Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death. Surgery (2002) 0.99
AIMP2 promotes TNFalpha-dependent apoptosis via ubiquitin-mediated degradation of TRAF2. J Cell Sci (2009) 0.99
Cell-surface receptor for complement component C1q (gC1qR) is a key regulator for lamellipodia formation and cancer metastasis. J Biol Chem (2011) 0.97
Novel regulatory interactions and activities of mammalian tRNA synthetases. Proteomics (2002) 0.97
MSC p43 required for axonal development in motor neurons. Proc Natl Acad Sci U S A (2009) 0.97
Ginsenoside Rh2 induces ligand-independent Fas activation via lipid raft disruption. Biochem Biophys Res Commun (2009) 0.96
Crystal structure of PRY-SPRY domain of human TRIM72. Proteins (2010) 0.96
Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. Biochem Biophys Res Commun (2007) 0.96
Proteome analysis of adipocyte lipid rafts reveals that gC1qR plays essential roles in adipogenesis and insulin signal transduction. Proteomics (2009) 0.95
Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts. Exp Mol Med (2004) 0.95
Lipid rafts are required for efficient signal transduction by CD1d. Biochem Biophys Res Commun (2005) 0.94
Determination of three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with ATM. J Biol Chem (2008) 0.94
Lipid raft proteome reveals that oxidative phosphorylation system is associated with the plasma membrane. Expert Rev Proteomics (2010) 0.94
Robotic single-port transumbilical total hysterectomy: a pilot study. J Gynecol Oncol (2011) 0.94
AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability. Cancer Res (2006) 0.94
The novel cytokine p43 induces IL-12 production in macrophages via NF-kappaB activation, leading to enhanced IFN-gamma production in CD4+ T cells. J Immunol (2006) 0.93
Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration. FASEB J (2012) 0.93
Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases. Am J Pathol (2007) 0.93
Control of adipogenesis by the SUMO-specific protease SENP2. Mol Cell Biol (2010) 0.93
MicroRNA profiling of a CD133(+) spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line. BMC Med Genomics (2012) 0.92
KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer. BMC Cancer (2012) 0.92
Structural separation of different extracellular activities in aminoacyl-tRNA synthetase-interacting multi-functional protein, p43/AIMP1. Biochem Biophys Res Commun (2006) 0.92
TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2. Biochem Biophys Res Commun (2010) 0.92
Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. Biochem Biophys Res Commun (2002) 0.92
The effect of composite pig islet-human endothelial cell grafts on the instant blood-mediated inflammatory reaction. Cell Transplant (2009) 0.91