| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development.
|
Hepatology
|
2009
|
3.16
|
|
2
|
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
|
PLoS One
|
2010
|
1.59
|
|
3
|
Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics.
|
J Antimicrob Chemother
|
2011
|
1.51
|
|
4
|
Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase.
|
Antimicrob Agents Chemother
|
2011
|
1.23
|
|
5
|
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
|
Antimicrob Agents Chemother
|
2008
|
1.18
|
|
6
|
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors.
|
Bioorg Med Chem Lett
|
2006
|
1.13
|
|
7
|
Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus.
|
J Hepatol
|
2012
|
1.11
|
|
8
|
A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19.
|
MBio
|
2013
|
1.11
|
|
9
|
Interferons, interferon inducers, and interferon-ribavirin in treatment of flavivirus-induced encephalitis in mice.
|
Antimicrob Agents Chemother
|
2003
|
1.09
|
|
10
|
Ribavirin antagonizes the in vitro anti-hepatitis C virus activity of 2'-C-methylcytidine, the active component of valopicitabine.
|
Antimicrob Agents Chemother
|
2006
|
1.00
|
|
11
|
Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor.
|
J Med Chem
|
2009
|
1.00
|
|
12
|
Exchanging the yellow fever virus envelope proteins with Modoc virus prM and E proteins results in a chimeric virus that is neuroinvasive in SCID mice.
|
J Virol
|
2004
|
0.92
|
|
13
|
The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication.
|
Biochem Pharmacol
|
2012
|
0.89
|
|
14
|
Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.
|
Antimicrob Agents Chemother
|
2011
|
0.87
|
|
15
|
Infection of SCID mice with Montana Myotis leukoencephalitis virus as a model for flavivirus encephalitis.
|
J Gen Virol
|
2002
|
0.86
|
|
16
|
Acute encephalitis, a poliomyelitis-like syndrome and neurological sequelae in a hamster model for flavivirus infections.
|
Brain Pathol
|
2003
|
0.85
|
|
17
|
Functional elucidation of antibacterial phage ORFans targeting Pseudomonas aeruginosa.
|
Cell Microbiol
|
2014
|
0.83
|
|
18
|
Substituted imidazopyridines as potent inhibitors of HCV replication.
|
J Hepatol
|
2009
|
0.82
|
|
19
|
Synthesis and anti-BVDV activity of acridones as new potential antiviral agents.
|
J Med Chem
|
2006
|
0.82
|
|
20
|
Angiogenic activity of hepatitis B and C viruses.
|
Antivir Chem Chemother
|
2012
|
0.80
|
|
21
|
Impact of direct virus-induced neuronal dysfunction and immunological damage on the progression of flavivirus (Modoc) encephalitis in a murine model.
|
J Neurovirol
|
2003
|
0.79
|
|
22
|
Synthesis and antiviral activity of an imidazo[1,2-a]pyrrolo[2,3-c]pyridine series against the bovine viral diarrhea virus.
|
Eur J Med Chem
|
2010
|
0.78
|
|
23
|
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.
|
J Med Chem
|
2013
|
0.78
|
|
24
|
3-Biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and analogues, novel Flaviviridae inhibitors.
|
Eur J Med Chem
|
2013
|
0.77
|
|
25
|
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
|
J Med Chem
|
2013
|
0.76
|
|
26
|
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.
|
J Med Chem
|
2014
|
0.75
|
|
27
|
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
|
J Gen Virol
|
2009
|
0.75
|
|
28
|
Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: further optimization of anti-hepatitis C virus activity.
|
Bioorg Med Chem Lett
|
2007
|
0.75
|
|
29
|
Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: from anti-pestivirus to anti-hepatitis C virus activity.
|
Bioorg Med Chem Lett
|
2006
|
0.75
|
|
30
|
Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivatives.
|
Antiviral Res
|
2010
|
0.75
|