|
1
|
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.
|
Nat Genet
|
2010
|
4.96
|
|
2
|
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
|
PLoS Genet
|
2013
|
2.39
|
|
3
|
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.
|
Cancer Res
|
2010
|
1.90
|
|
4
|
Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants.
|
Hum Mutat
|
2012
|
1.77
|
|
5
|
AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.
|
Cancer Epidemiol Biomarkers Prev
|
2007
|
1.75
|
|
6
|
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.
|
Breast Cancer Res
|
2011
|
1.22
|
|
7
|
Significant contribution of germline BRCA2 rearrangements in male breast cancer families.
|
Cancer Res
|
2004
|
1.18
|
|
8
|
Contribution of bioinformatics predictions and functional splicing assays to the interpretation of unclassified variants of the BRCA genes.
|
Eur J Hum Genet
|
2011
|
1.16
|
|
9
|
One-year longitudinal study of fatigue, cognitive functions, and quality of life after adjuvant radiotherapy for breast cancer.
|
Int J Radiat Oncol Biol Phys
|
2010
|
1.12
|
|
10
|
Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.
|
Hum Mutat
|
2012
|
0.98
|
|
11
|
Multiple sequence variants of BRCA2 exon 7 alter splicing regulation.
|
J Med Genet
|
2012
|
0.94
|
|
12
|
Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene.
|
Int J Cancer
|
2005
|
0.91
|
|
13
|
Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.
|
Hum Mol Genet
|
2011
|
0.89
|
|
14
|
A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.89
|
|
15
|
The BRCA1 c.5434C->G (p.Pro1812Ala) variant induces a deleterious exon 23 skipping by affecting exonic splicing regulatory elements.
|
J Med Genet
|
2010
|
0.88
|
|
16
|
Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
0.86
|
|
17
|
BCL-2/JH translocation in peripheral blood lymphocytes of unexposed individuals: lack of seasonal variations in frequency and molecular features.
|
Int J Cancer
|
2003
|
0.83
|
|
18
|
BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 germ-line mutations.
|
Cancer Epidemiol Biomarkers Prev
|
2003
|
0.79
|
|
19
|
Two novel variants in the 3'UTR of the BRCA1 gene in familial breast and/or ovarian cancer.
|
Breast Cancer Res Treat
|
2010
|
0.78
|
|
20
|
A one-step prescreening for point mutations and large rearrangement in BRCA1 and BRCA2 genes using quantitative polymerase chain reaction and high-resolution melting curve analysis.
|
Genet Test Mol Biomarkers
|
2010
|
0.78
|