1
|
Guidelines for the use and interpretation of assays for monitoring autophagy.
|
Autophagy
|
2012
|
20.08
|
2
|
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth.
|
Cancer Res
|
2009
|
6.15
|
3
|
Recombinant origin of the retrovirus XMRV.
|
Science
|
2011
|
3.54
|
4
|
An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells.
|
Proc Natl Acad Sci U S A
|
2007
|
3.54
|
5
|
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.
|
Cancer Res
|
2002
|
2.99
|
6
|
Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.
|
J Clin Oncol
|
2013
|
2.59
|
7
|
Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex.
|
Proc Natl Acad Sci U S A
|
2003
|
1.99
|
8
|
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.
|
Cancer Res
|
2007
|
1.97
|
9
|
Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis.
|
Cancer Res
|
2009
|
1.88
|
10
|
Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors.
|
Genes Cancer
|
2010
|
1.63
|
11
|
Kaposi's sarcoma-associated herpesvirus K-bZIP is a coregulator of K-Rta: physical association and promoter-dependent transcriptional repression.
|
J Virol
|
2003
|
1.60
|
12
|
Expression profile of tyrosine kinases in breast cancer.
|
Clin Cancer Res
|
2002
|
1.58
|
13
|
miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes.
|
Prostate
|
2010
|
1.55
|
14
|
MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells.
|
J Biol Chem
|
2011
|
1.52
|
15
|
Nonreceptor tyrosine kinases in prostate cancer.
|
Neoplasia
|
2007
|
1.50
|
16
|
The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformation.
|
Cancer Biol Ther
|
2004
|
1.50
|
17
|
Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK.
|
Oncogene
|
2004
|
1.48
|
18
|
Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer.
|
Cancer Res
|
2009
|
1.38
|
19
|
Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication.
|
Proc Natl Acad Sci U S A
|
2004
|
1.37
|
20
|
Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase.
|
Int J Cancer
|
2008
|
1.36
|
21
|
JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.
|
Proc Natl Acad Sci U S A
|
2013
|
1.34
|
22
|
Interleukin-6 regulates androgen synthesis in prostate cancer cells.
|
Clin Cancer Res
|
2009
|
1.32
|
23
|
K-bZIP of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) binds KSHV/HHV-8 Rta and represses Rta-mediated transactivation.
|
J Virol
|
2003
|
1.32
|
24
|
KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.
|
Proc Natl Acad Sci U S A
|
2010
|
1.31
|
25
|
MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth.
|
PLoS One
|
2012
|
1.30
|
26
|
Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells.
|
Cancer Res
|
2010
|
1.29
|
27
|
ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.
|
Neoplasia
|
2012
|
1.28
|
28
|
Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification.
|
J Virol
|
2005
|
1.26
|
29
|
Negative modulation of androgen receptor transcriptional activity by Daxx.
|
Mol Cell Biol
|
2004
|
1.26
|
30
|
Molecular alterations associated with LNCaP cell progression to androgen independence.
|
Prostate
|
2004
|
1.26
|
31
|
Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific.
|
J Biol Chem
|
2009
|
1.23
|
32
|
Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.
|
Cancer Res
|
2008
|
1.21
|
33
|
Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as transcriptional repressors for gamma-2 herpesvirus lytic replication.
|
Mol Cell Biol
|
2003
|
1.21
|
34
|
Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase.
|
Cancer Res
|
2009
|
1.21
|
35
|
Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
|
Cancer Res
|
2006
|
1.20
|
36
|
Functional analysis of 44 mutant androgen receptors from human prostate cancer.
|
Cancer Res
|
2002
|
1.20
|
37
|
Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells.
|
J Biol Chem
|
2005
|
1.19
|
38
|
Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G1 growth arrest.
|
J Virol
|
2003
|
1.16
|
39
|
ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer.
|
Autophagy
|
2009
|
1.14
|
40
|
Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP.
|
J Virol
|
2006
|
1.14
|
41
|
Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications.
|
Cancer Res
|
2006
|
1.13
|
42
|
Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer.
|
Cancer Res
|
2009
|
1.13
|
43
|
Signal pathways in up-regulation of chemokines by tyrosine kinase MER/NYK in prostate cancer cells.
|
Cancer Res
|
2004
|
1.12
|
44
|
Characterization of the chromosomal binding sites and dimerization partners of the viral oncoprotein Meq in Marek's disease virus-transformed T cells.
|
J Virol
|
2003
|
1.12
|
45
|
Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: a converging transforming pathway for avian oncoviruses.
|
Proc Natl Acad Sci U S A
|
2005
|
1.11
|
46
|
ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway.
|
J Biol Chem
|
2004
|
1.08
|
47
|
Impairment of the DNA repair and growth arrest pathways by p53R2 silencing enhances DNA damage-induced apoptosis in a p53-dependent manner in prostate cancer cells.
|
Mol Cancer Res
|
2008
|
1.06
|
48
|
The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells.
|
J Thorac Oncol
|
2009
|
1.06
|
49
|
Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2.
|
Mol Endocrinol
|
2006
|
1.06
|
50
|
A comprehensive analysis of recruitment and transactivation potential of K-Rta and K-bZIP during reactivation of Kaposi's sarcoma-associated herpesvirus.
|
Virology
|
2009
|
1.06
|
51
|
Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis.
|
J Biol Chem
|
2002
|
1.05
|
52
|
NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator.
|
J Virol
|
2009
|
1.04
|
53
|
Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer.
|
PLoS One
|
2013
|
1.04
|
54
|
vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus.
|
J Virol
|
2005
|
1.03
|
55
|
Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells.
|
Prostate
|
2005
|
1.02
|
56
|
Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop.
|
Mol Cell Biol
|
2012
|
1.02
|
57
|
ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes.
|
Prostate
|
2006
|
1.02
|
58
|
Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells.
|
J Biol Chem
|
2002
|
1.02
|
59
|
Multiplex analysis of intracellular signaling pathways in lymphoid cells by microbead suspension arrays.
|
Mol Cell Proteomics
|
2005
|
1.00
|
60
|
Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation.
|
PLoS Pathog
|
2013
|
0.98
|
61
|
Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins.
|
Am J Cancer Res
|
2011
|
0.97
|
62
|
Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen.
|
J Biol Chem
|
2011
|
0.97
|
63
|
Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.
|
Oncogene
|
2003
|
0.96
|
64
|
ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines.
|
J Biol Chem
|
2009
|
0.96
|
65
|
Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.
|
Endocr Relat Cancer
|
2010
|
0.95
|
66
|
Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A.
|
J Virol
|
2013
|
0.94
|
67
|
Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells.
|
Cancer Res
|
2006
|
0.94
|
68
|
Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage.
|
J Biol Chem
|
2004
|
0.93
|
69
|
RNA editing of androgen receptor gene transcripts in prostate cancer cells.
|
J Biol Chem
|
2008
|
0.93
|
70
|
Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model.
|
Mol Cancer Ther
|
2010
|
0.90
|
71
|
Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor.
|
J Virol
|
2011
|
0.90
|
72
|
Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration.
|
Int J Cancer
|
2011
|
0.90
|
73
|
Marek's disease virus-encoded vIL-8 gene is involved in early cytolytic infection but dispensable for establishment of latency.
|
J Virol
|
2004
|
0.89
|
74
|
BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer.
|
J Cell Biochem
|
2007
|
0.89
|
75
|
Heptad repeats regulate protein phosphatase 2a recruitment to I-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax.
|
J Biol Chem
|
2007
|
0.89
|
76
|
Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs.
|
Mol Pharmacol
|
2012
|
0.89
|
77
|
The oncogenic potential of a prostate cancer-derived androgen receptor mutant.
|
Prostate
|
2007
|
0.88
|
78
|
The role of tyrosine kinase Etk/Bmx in EGF-induced apoptosis of MDA-MB-468 breast cancer cells.
|
Oncogene
|
2004
|
0.88
|
79
|
A lytic viral long noncoding RNA modulates the function of a latent protein.
|
J Virol
|
2013
|
0.87
|
80
|
Recombinant Marek's disease virus (MDV) lacking the Meq oncogene confers protection against challenge with a very virulent plus strain of MDV.
|
Vaccine
|
2008
|
0.86
|
81
|
Elevated expression of tyrosine kinase DDR2 in primary biliary cirrhosis.
|
Autoimmunity
|
2002
|
0.86
|
82
|
Homodimerization of Marek's disease virus-encoded Meq protein is not sufficient for transformation of lymphocytes in chickens.
|
J Virol
|
2008
|
0.85
|
83
|
Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization.
|
Endocr Relat Cancer
|
2012
|
0.85
|
84
|
KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor.
|
J Med Chem
|
2014
|
0.84
|
85
|
Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a Marek's disease virus oncoprotein, Meq.
|
J Virol
|
2013
|
0.84
|
86
|
In vitro characterization of the Meq proteins of Marek's disease virus vaccine strain CVI988.
|
Virus Res
|
2009
|
0.84
|
87
|
The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi's sarcoma associated herpesvirus reactivation.
|
BMC Genomics
|
2013
|
0.82
|
88
|
c-Jun controls the efficiency of MAP kinase signaling by transcriptional repression of MAP kinase phosphatases.
|
Exp Cell Res
|
2005
|
0.82
|
89
|
Modeling truncated AR expression in a natural androgen responsive environment and identification of RHOB as a direct transcriptional target.
|
PLoS One
|
2012
|
0.82
|
90
|
Novel flavonoids with antiproliferative activities against breast cancer cells.
|
J Med Chem
|
2011
|
0.81
|
91
|
Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.
|
Oncogene
|
2002
|
0.81
|
92
|
Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells.
|
Assay Drug Dev Technol
|
2010
|
0.79
|
93
|
Ligand-independent activation of the arylhydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment.
|
Biol Chem
|
2011
|
0.78
|
94
|
Multiplex analysis of Src family kinase signaling by microbead suspension arrays.
|
Assay Drug Dev Technol
|
2010
|
0.78
|
95
|
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors.
|
PLoS One
|
2013
|
0.78
|
96
|
Both homo and heterodimers of Marek's disease virus encoded Meq protein contribute to transformation of lymphocytes in chickens.
|
Virology
|
2010
|
0.77
|
97
|
Cocoa procyanidins inhibit proliferation and angiogenic signals in human dermal microvascular endothelial cells following stimulation by low-level H2O2.
|
Exp Biol Med (Maywood)
|
2004
|
0.77
|
98
|
Quantitative analysis of autophagy using advanced 3D fluorescence microscopy.
|
J Vis Exp
|
2013
|
0.77
|
99
|
Pentameric procyanidins isolated from Theobroma cacao seeds selectively downregulate ErbB2 in human aortic endothelial cells.
|
Exp Biol Med (Maywood)
|
2004
|
0.76
|
100
|
Retraction: MMP-13 is involved in oral cancer cell metastasis.
|
Oncotarget
|
2016
|
0.76
|
101
|
An improved ChIP-seq peak detection system for simultaneously identifying post-translational modified transcription factors by combinatorial fusion, using SUMOylation as an example.
|
BMC Genomics
|
2014
|
0.76
|
102
|
Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.
|
Nat Med
|
2016
|
0.75
|
103
|
Elevated C-met in thymic dendritic cells of New Zealand Black mice.
|
Dev Immunol
|
2002
|
0.75
|