| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic.
|
Neuropsychopharmacology
|
2005
|
1.24
|
|
2
|
SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile.
|
Neuropsychopharmacology
|
2006
|
1.14
|
|
3
|
SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.
|
J Pharmacol Exp Ther
|
2002
|
0.95
|
|
4
|
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia.
|
Pharmacol Biochem Behav
|
2008
|
0.89
|
|
5
|
SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.
|
CNS Drug Rev
|
2003
|
0.89
|
|
6
|
SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties.
|
J Pharmacol Exp Ther
|
2002
|
0.88
|
|
7
|
Regioselective cobalt-catalyzed formation of bicyclic 3- and 4-aminopyridines.
|
Org Lett
|
2011
|
0.86
|
|
8
|
In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [(11)C]befloxatone and the multi-injection approach.
|
J Cereb Blood Flow Metab
|
2009
|
0.86
|
|
9
|
Synthesis of aminopyridines and aminopyridones by cobalt-catalyzed [2+2+2] cycloadditions involving yne-ynamides: scope, limitations, and mechanistic insights.
|
Chemistry
|
2012
|
0.85
|
|
10
|
Polyamine participation in the maturation of glycoprotein fucosylation, but not sialylation, in rat small intestine.
|
Pediatr Res
|
2002
|
0.83
|
|
11
|
Synthesis and in vivo imaging properties of [11C]befloxatone: a novel highly potent positron emission tomography ligand for mono-amine oxidase-A.
|
Bioorg Med Chem Lett
|
2003
|
0.83
|
|
12
|
Mapping the cerebral monoamine oxidase type A: positron emission tomography characterization of the reversible selective inhibitor [11C]befloxatone.
|
J Pharmacol Exp Ther
|
2003
|
0.83
|
|
13
|
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile.
|
Neuropsychopharmacology
|
2003
|
0.81
|
|
14
|
Synthesis and biological evaluation of analogues of M6G.
|
Eur J Med Chem
|
2011
|
0.80
|
|
15
|
[(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate.
|
Synapse
|
2010
|
0.78
|
|
16
|
Design and synthesis of novel imidazo[1,2-a]quinoxalines as PDE4 inhibitors.
|
Bioorg Med Chem
|
2004
|
0.77
|
|
17
|
Chemical biology: contribution to molecular therapeutic innovation--a new role for chemistry? Report from the thematic symposium organized by the SCT (French Medicinal Chemistry Society), November 26th, 2013.
|
ACS Chem Biol
|
2014
|
0.75
|
|
18
|
Synthesis of new potentially bioactive bicyclic 2-pyridones.
|
Molecules
|
2005
|
0.75
|
|
19
|
Interfacing chemical biology and drug discovery: report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2-4, 2014, Rouen, France.
|
ACS Chem Biol
|
2014
|
0.75
|
|
20
|
Ring expansion of cyclic β-amino alcohols induced by diethylaminosulfur trifluoride: synthesis of cyclic amines with a tertiary fluorine at C3.
|
J Org Chem
|
2012
|
0.75
|
|
21
|
Solid-phase syntheses of 6-arylpyridazin-3(2H)-ones.
|
J Comb Chem
|
2005
|
0.75
|