Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2.

PubWeight™: 1.99‹?› | Rank: Top 2%

🔗 View Article (PMID 12596863)

Published in Biosci Biotechnol Biochem on December 01, 2002

Authors

Noritaka Iwai1, Kazuo Nagai, Masaaki Wachi

Author Affiliations

1: Department of Bioengineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan.

Articles citing this

The selective value of bacterial shape. Microbiol Mol Biol Rev (2006) 3.97

Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus. Proc Natl Acad Sci U S A (2006) 3.19

How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Microbiol Mol Biol Rev (2008) 3.12

A self-associating protein critical for chromosome attachment, division, and polar organization in caulobacter. Cell (2008) 3.02

Conditional lethality, division defects, membrane involution, and endocytosis in mre and mrd shape mutants of Escherichia coli. J Bacteriol (2007) 2.34

Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing. EMBO J (2010) 2.25

The bacterial actin-like cytoskeleton. Microbiol Mol Biol Rev (2006) 2.18

Sculpting the bacterial cell. Curr Biol (2009) 2.04

Two independent spiral structures control cell shape in Caulobacter. Proc Natl Acad Sci U S A (2005) 2.03

Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. Genes Dev (2006) 1.93

Determination of bacterial rod shape by a novel cytoskeletal membrane protein. EMBO J (2008) 1.72

Bacterial motility complexes require the actin-like protein, MreB and the Ras homologue, MglA. EMBO J (2009) 1.71

Unstable Escherichia coli L forms revisited: growth requires peptidoglycan synthesis. J Bacteriol (2007) 1.69

Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J Bacteriol (2008) 1.65

A22 disrupts the bacterial actin cytoskeleton by directly binding and inducing a low-affinity state in MreB. Biochemistry (2009) 1.65

Actin-like cytoskeleton filaments contribute to cell mechanics in bacteria. Proc Natl Acad Sci U S A (2010) 1.61

The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli. Mol Microbiol (2007) 1.54

MreB drives de novo rod morphogenesis in Caulobacter crescentus via remodeling of the cell wall. J Bacteriol (2009) 1.49

Uncovering the mystery of gliding motility in the myxobacteria. Annu Rev Genet (2011) 1.32

Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity. Mol Microbiol (2012) 1.31

The structure and function of bacterial actin homologs. Cold Spring Harb Perspect Biol (2010) 1.27

GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB. J Bacteriol (2006) 1.24

Positioning of chemosensory clusters in E. coli and its relation to cell division. EMBO J (2007) 1.24

Bactofilins, a ubiquitous class of cytoskeletal proteins mediating polar localization of a cell wall synthase in Caulobacter crescentus. EMBO J (2009) 1.23

In vivo localizations of membrane stress controllers PspA and PspG in Escherichia coli. Mol Microbiol (2009) 1.17

Manipulating each MreB of Bdellovibrio bacteriovorus gives diverse morphological and predatory phenotypes. J Bacteriol (2009) 1.17

Bacterial actin MreB forms antiparallel double filaments. Elife (2014) 1.14

Mechanical control of bacterial cell shape. Biophys J (2011) 1.08

Growth conditions regulate the requirements for Caulobacter chromosome segregation. J Bacteriol (2008) 1.06

Physics of bacterial morphogenesis. Microbiol Mol Biol Rev (2011) 1.03

Independent segregation of the two arms of the Escherichia coli ori region requires neither RNA synthesis nor MreB dynamics. J Bacteriol (2010) 0.97

A Novel indole compound that inhibits Pseudomonas aeruginosa growth by targeting MreB is a substrate for MexAB-OprM. J Bacteriol (2007) 0.93

A Caulobacter MreB mutant with irregular cell shape exhibits compensatory widening to maintain a preferred surface area to volume ratio. Mol Microbiol (2014) 0.90

Fine-Tuning of the Cpx Envelope Stress Response Is Required for Cell Wall Homeostasis in Escherichia coli. MBio (2016) 0.89

Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments. Mol Microbiol (2009) 0.89

Bacterial actin and tubulin homologs in cell growth and division. Curr Biol (2015) 0.87

Mutations in cell elongation genes mreB, mrdA and mrdB suppress the shape defect of RodZ-deficient cells. Mol Microbiol (2013) 0.87

Salinity-dependent impacts of ProQ, Prc, and Spr deficiencies on Escherichia coli cell structure. J Bacteriol (2014) 0.86

Dynamics of the serine chemoreceptor in the Escherichia coli inner membrane: a high-speed single-molecule tracking study. Biophys J (2014) 0.83

The bacterial cytoskeleton modulates motility, type 3 secretion, and colonization in Salmonella. PLoS Pathog (2012) 0.80

A Bacterial Cell Shape-Determining Inhibitor. ACS Chem Biol (2016) 0.79

Phylogenetic analyses and detection of viridans streptococci based on sequences and denaturing gradient gel electrophoresis of the rod shape-determining protein gene. J Oral Microbiol (2009) 0.79

Natural transformation occurs independently of the essential actin-like MreB cytoskeleton in Legionella pneumophila. Sci Rep (2015) 0.79

Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7. Proc Natl Acad Sci U S A (2014) 0.78

Fungal lectin of Peltigera canina induces chemotropism of compatible Nostoc cells by constriction-relaxation pulses of cyanobiont cytoskeleton. Plant Signal Behav (2011) 0.78

Growth of curved and helical bacterial cells. Soft Matter (2012) 0.78

Intergenerational continuity of cell shape dynamics in Caulobacter crescentus. Sci Rep (2015) 0.77

Anucleate cell blue assay: a useful tool for identifying novel type II topoisomerase inhibitors. Antimicrob Agents Chemother (2006) 0.77

Polar localization of a tripartite complex of the two-component system DcuS/DcuR and the transporter DctA in Escherichia coli depends on the sensor kinase DcuS. PLoS One (2014) 0.77

Route of intrabacterial nanotransportation system for CagA in Helicobacter pylori. Med Mol Morphol (2015) 0.77

A microfluidic platform for profiling biomechanical properties of bacteria. Lab Chip (2014) 0.76

The effect of inhibition of host MreB on the infection of thermophilic phage GVE2 in high temperature environment. Sci Rep (2014) 0.76

A Cardiolipin-Deficient Mutant of Rhodobacter sphaeroides Has an Altered Cell Shape and Is Impaired in Biofilm Formation. J Bacteriol (2015) 0.76

Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics. Int J Mol Sci (2015) 0.76

Cytoskeletal Proteins in Caulobacter crescentus: Spatial Orchestrators of Cell Cycle Progression, Development, and Cell Shape. Subcell Biochem (2017) 0.76

A Spatial Control for Correct Timing of Gene Expression during the Escherichia coli Cell Cycle. Genes (Basel) (2016) 0.75

Detection and analysis of Lactobacillus paracasei penicillin-binding proteins revealed the presence of cholate-sensitive penicillin-binding protein 3 and an elongated cell shape in a cholate-sensitive strain. Biosci Microbiota Food Health (2016) 0.75

PBP1B glycosyltransferase and transpeptidase activities play different essential roles during the de novo regeneration of rod-shaped morphology in Escherichia coli. J Bacteriol (2017) 0.75

YodL and YisK Possess Shape-Modifying Activities That Are Suppressed by Mutations in Bacillus subtilis mreB and mbl. J Bacteriol (2016) 0.75

Chemical genetics: reshaping biology through chemistry. HFSP J (2007) 0.75

Polar localization of MreB actin is inhibited by anionic phospholipids in the rod-shaped bacterium Escherichia coli. Curr Genet (2017) 0.75

Articles by these authors

MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell (2005) 4.63

Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. Genes Dev (2006) 1.93

Synthesis and antibacterial activity of a novel series of potent DNA gyrase inhibitors. Pyrazole derivatives. J Med Chem (2004) 1.58

Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol (2004) 1.15

Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. Carcinogenesis (2004) 1.13

Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production. Appl Environ Microbiol (2007) 1.09

Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring. Bioorg Med Chem (2004) 1.09

Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death. Biochem Biophys Res Commun (2002) 1.07

Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Life Sci (2009) 1.04

Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-alpha, IL-1, and RANKL. J Cell Physiol (2002) 1.02

TolC-dependent exclusion of porphyrins in Escherichia coli. J Bacteriol (2008) 1.01

A 4-aminofurazan derivative-A189-inhibits assembly of bacterial cell division protein FtsZ in vitro and in vivo. Microbiol Immunol (2006) 1.00

Dark-induced mRNA instability involves RNase E/G-type endoribonuclease cleavage at the AU-box and SD sequences in cyanobacteria. Mol Genet Genomics (2007) 1.00

RNase G-dependent degradation of the eno mRNA encoding a glycolysis enzyme enolase in Escherichia coli. Biosci Biotechnol Biochem (2002) 0.97

Structural and functional characterization of the LldR from Corynebacterium glutamicum: a transcriptional repressor involved in L-lactate and sugar utilization. Nucleic Acids Res (2008) 0.95

Effects of high hydrostatic pressure on bacterial cytoskeleton FtsZ polymers in vivo and in vitro. Microbiology (2004) 0.95

Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A (2006) 0.94

Synthetic approach to exo-endo cross-conjugated cyclohexadienones and its application to the syntheses of dehydrobrachylaenolide, isodehydrochamaecynone, and trans-isodehydrochamaecynone. J Nat Prod (2003) 0.94

FtsZ-dependent localization of GroEL protein at possible division sites. Genes Cells (2004) 0.94

Effects of Korean white ginseng extracts on obesity in high-fat diet-induced obese mice. Cytotechnology (2010) 0.93

Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity. Bioorg Med Chem Lett (2004) 0.93

Synthesis and antibacterial activity of a novel series of DNA gyrase inhibitors: 5-[(E)-2-arylvinyl]pyrazoles. Bioorg Med Chem Lett (2005) 0.93

Insulin-dependent adipogenesis in stromal ST2 cells derived from murine bone marrow. Biosci Biotechnol Biochem (2003) 0.92

Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha). Biochem Pharmacol (2005) 0.92

Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli. Biosci Biotechnol Biochem (2004) 0.91

The efficacy of ascofuranone in a consecutive treatment on Trypanosoma brucei brucei in mice. Parasitol Int (2003) 0.91

Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Biochem Pharmacol (2011) 0.90

Transcriptional analysis of the Escherichia coli mreBCD genes responsible for morphogenesis and chromosome segregation. Biosci Biotechnol Biochem (2006) 0.89

Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro. Eur J Pharmacol (2004) 0.89

Structure-activity relationship study of the bacterial actin-like protein MreB inhibitors: effects of substitution of benzyl group in S-benzylisothiourea. Biosci Biotechnol Biochem (2007) 0.89

Safflower polysaccharides activate the transcription factor NF-kappa B via Toll-like receptor 4 and induce cytokine production by macrophages. Int Immunopharmacol (2002) 0.89

Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex. Biochim Biophys Acta (2009) 0.89

Curcumin inhibits the proliferation and mineralization of cultured osteoblasts. Eur J Pharmacol (2006) 0.89

Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice. J Nutr Biochem (2012) 0.89

Anti-infectious effect of S-benzylisothiourea compound A22, which inhibits the actin-like protein, MreB, in Shigella flexneri. Biol Pharm Bull (2008) 0.87

ERK and p38 MAP kinase are involved in downregulation of cell surface TNF receptor 1 induced by acetoxycycloheximide. Int Immunopharmacol (2008) 0.87

Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells. Exp Cell Res (2002) 0.87

A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli. PLoS One (2011) 0.87

Effects of a Citrus depressa Hayata (shiikuwasa) extract on obesity in high-fat diet-induced obese mice. Phytomedicine (2011) 0.87

Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol Pharm Bull (2004) 0.87

Direct evidence for cyanide-insensitive quinol oxidase (alternative oxidase) in apicomplexan parasite Cryptosporidium parvum: phylogenetic and therapeutic implications. Biochem Biophys Res Commun (2004) 0.86

Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum. J Biosci Bioeng (2008) 0.86

Extracellular ATP inhibits apoptosis and maintains cell viability by inducing autocrine production of interleukin-4 in a myeloid progenitor cell line. Int Immunopharmacol (2004) 0.85

N,N'-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cells. J Antibiot (Tokyo) (2011) 0.85

Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling. Biochem Biophys Res Commun (2011) 0.85

Purification of active recombinant trypanosome alternative oxidase. FEBS Lett (2003) 0.85

3' Untranslated region-dependent degradation of the aceA mRNA, encoding the glyoxylate cycle enzyme isocitrate lyase, by RNase E/G in Corynebacterium glutamicum. Appl Environ Microbiol (2012) 0.85

Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice. Biochem Pharmacol (2010) 0.85

The CGL2612 protein from Corynebacterium glutamicum is a drug resistance-related transcriptional repressor: structural and functional analysis of a newly identified transcription factor from genomic DNA analysis. J Biol Chem (2005) 0.84

Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin. Antimicrob Agents Chemother (2009) 0.84

Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol. Parasitol Int (2005) 0.84

A decreased level of FtsZ is responsible for inviability of RNase E-deficient cells. Genes Cells (2005) 0.84

Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo. Eur J Pharmacol (2010) 0.83

Tributyltin and triphenyltin inhibit osteoclast differentiation through a retinoic acid receptor-dependent signaling pathway. Biochem Biophys Res Commun (2007) 0.83

Inhibitory effect of luteolin on osteoclast differentiation and function. Cytotechnology (2010) 0.83

Berberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. Plant Mol Biol (2012) 0.83

Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods. J Biosci Bioeng (2012) 0.83

Coptisine inhibits RANKL-induced NF-κB phosphorylation in osteoclast precursors and suppresses function through the regulation of RANKL and OPG gene expression in osteoblastic cells. J Nat Med (2011) 0.82

Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts. J Cell Biochem (2012) 0.82

Increased production of pyruvic acid by Escherichia coli RNase G mutants in combination with cra mutations. Appl Microbiol Biotechnol (2007) 0.82

Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense. Bioorg Med Chem Lett (2011) 0.82

Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes. Biofactors (2012) 0.81

Enzymatic hydrolysis of structurally diverse phthalic acid esters by porcine and bovine pancreatic cholesterol esterases. Chemosphere (2010) 0.81

BE-18591 as a new H(+)/Cl(-) symport ionophore that inhibits immunoproliferation and gastritis. FEBS Lett (2002) 0.81

Ectodomain shedding of TNF receptor 1 induced by protein synthesis inhibitors regulates TNF-alpha-mediated activation of NF-kappaB and caspase-8. Exp Cell Res (2008) 0.81

Honokiol inhibits osteoclast differentiation and function in vitro. Biol Pharm Bull (2010) 0.81

Isolation of a new antibiotic, alaremycin, structurally related to 5-aminolevulinic acid from Streptomyces sp. A012304. Biosci Biotechnol Biochem (2005) 0.80

Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes. J Nat Med (2011) 0.80

The cytotoxic macrolide FD-891 induces caspase-8-dependent mitochondrial release of cytochrome c and subsequent apoptosis in human leukemia Jurkat cells. J Antibiot (Tokyo) (2009) 0.80

Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture. Biochem Pharmacol (2006) 0.80

Fluorescent phospholipid analogs as microscopic probes for detection of the mycolic acid-containing layer in Corynebacterium glutamicum: detecting alterations in the mycolic acid-containing layer following ethambutol treatment. Biosci Biotechnol Biochem (2005) 0.80

Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells. Biochem Biophys Res Commun (2002) 0.80

Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells. Biol Pharm Bull (2010) 0.80

An inhibitory effect of chrysoeriol on platelet-derived growth factor (PDGF)-induced proliferation and PDGF receptor signaling in human aortic smooth muscle cells. J Pharmacol Sci (2009) 0.80

Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum. Appl Microbiol Biotechnol (2009) 0.80

Characterization of the nitrate-nitrite transporter of the major facilitator superfamily (the nrtP gene product) from the cyanobacterium Nostoc punctiforme strain ATCC 29133. Biosci Biotechnol Biochem (2006) 0.79

Transcriptional analysis of the ostA/imp gene involved in organic solvent sensitivity in Escherichia coli. Biosci Biotechnol Biochem (2004) 0.79

Fargesin, a component of Flos Magnoliae, stimulates glucose uptake in L6 myotubes. J Nat Med (2012) 0.79

Corynebacterium glutamicum RNase E/G-type endoribonuclease encoded by NCgl2281 is involved in the 5' maturation of 5S rRNA. Arch Microbiol (2011) 0.79

A Corynebacterium glutamicum rnhA recG double mutant showing lysozyme-sensitivity, temperature-sensitive growth, and UV-sensitivity. Biosci Biotechnol Biochem (2003) 0.79

Cytoplasmic acidification may occur in high-pressure carbon dioxide-treated Escherichia coli K12. Biosci Biotechnol Biochem (2007) 0.79

RNase E is required for induction of the glutamate-dependent acid resistance system in Escherichia coli. Biosci Biotechnol Biochem (2007) 0.78

Bioactive guaianolides from siyekucai (Ixeris chinensis). J Nat Prod (2006) 0.78