Published in Immunology on March 01, 2003
N-acetylcysteine -- passe-partout or much ado about nothing? Br J Clin Pharmacol (2006) 1.23
Antigen specific correlations of cellular immune responses in human leishmaniasis suggests mechanisms for immunoregulation. Clin Exp Immunol (2004) 1.22
Role of ROS in ischemia-induced lung angiogenesis. Am J Physiol Lung Cell Mol Physiol (2010) 1.09
Are reactive oxygen species always detrimental to pathogens? Antioxid Redox Signal (2013) 0.95
Immunoregulation in human American leishmaniasis: balancing pathology and protection. Parasite Immunol (2014) 0.90
Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase. Antimicrob Agents Chemother (2006) 0.90
DETC induces Leishmania parasite killing in human in vitro and murine in vivo models: a promising therapeutic alternative in Leishmaniasis. PLoS One (2010) 0.87
N-acetyl-L: -cysteine reduces the parasitism of BALB/c mice infected with Leishmania amazonensis. Parasitol Res (2007) 0.79
N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis. Mem Inst Oswaldo Cruz (2017) 0.75
A novel function for kojic acid, a secondary metabolite from Aspergillus fungi, as antileishmanial agent. PLoS One (2014) 0.75
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol (1988) 14.21
The regulation of immunity to Leishmania major. Annu Rev Immunol (1995) 8.05
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J Exp Med (1992) 7.80
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J Immunol (1990) 5.87
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med (1997) 5.56
Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. Proc Natl Acad Sci U S A (1991) 4.95
Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J Immunol (1989) 4.44
Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J Immunol (1990) 4.36
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J Exp Med (1995) 4.12
Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J Exp Med (1994) 3.02
CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major. J Exp Med (1994) 2.88
Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci U S A (1998) 2.35
Glutathione deficiency and human immunodeficiency virus infection. Lancet (1992) 2.25
Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis. Eur J Immunol (1989) 2.04
Cytokine profile and pathology in human leishmaniasis. Braz J Med Biol Res (1998) 1.99
N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Adv Pharmacol (1997) 1.95
Flow cytometric determination of cellular sources and frequencies of key cytokine-producing lymphocytes directed against recombinant LACK and soluble Leishmania antigen in human cutaneous leishmaniasis. Infect Immun (2001) 1.90
Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major. Eur J Immunol (1994) 1.82
Immunopathology of experimental cutaneous leishmaniasis. Am J Pathol (1984) 1.65
Changes in the precursor frequencies of IL-4 and IFN-gamma secreting CD4+ cells correlate with resolution of lesions in murine cutaneous leishmaniasis. J Immunol (1992) 1.64
Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major. Proc Natl Acad Sci U S A (1994) 1.47
Synergistic cooperation between T cell lymphokines for induction of the nitric oxide synthase gene in murine peritoneal macrophages. J Immunol (1993) 1.34
The polarization of T(h)1/T(h)2 balance is dependent on the intracellular thiol redox status of macrophages due to the distinctive cytokine production. Int Immunol (2002) 1.29
HIV-induced cysteine deficiency and T-cell dysfunction--a rationale for treatment with N-acetylcysteine. Immunol Today (1992) 1.08
Different Leishmania species determine distinct profiles of immune and histopathological responses in CBA mice. Microbes Infect (2000) 1.05
Cytokine-producing T cell subsets in human leishmaniasis. Arch Immunol Ther Exp (Warsz) (2000) 1.00
Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy. J Exp Med (1999) 0.89
Leishmania major: targeting IL-4 in successful immunomodulation of murine infection. Exp Parasitol (1996) 0.88
Histopathologic changes induced by vaccination in experimental cutaneous leishmaniasis of BALB/c mice. Am J Pathol (1987) 0.85
N-acetylcysteine as chemoprotectant in cancer chemotherapy. Lancet (1991) 0.81
Up-regulation of Th1-type responses in mucosal leishmaniasis patients. Infect Immun (2002) 2.90
Decreased in situ expression of interleukin-10 receptor is correlated with the exacerbated inflammatory and cytotoxic responses observed in mucosal leishmaniasis. Infect Immun (2005) 2.29
Activated inflammatory T cells correlate with lesion size in human cutaneous leishmaniasis. Immunol Lett (2005) 1.94
Exacerbated inflammatory cellular immune response characteristics of HAM/TSP is observed in a large proportion of HTLV-I asymptomatic carriers. BMC Infect Dis (2004) 1.39
Monocytes from patients with indeterminate and cardiac forms of Chagas' disease display distinct phenotypic and functional characteristics associated with morbidity. Infect Immun (2004) 1.33
Functional IL-10 gene polymorphism is associated with Chagas disease cardiomyopathy. J Infect Dis (2009) 1.26
Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease. Semin Immunopathol (2012) 1.26
Current concepts in immunoregulation and pathology of human Chagas disease. Curr Opin Infect Dis (2008) 1.17
Disparate immunoregulatory potentials for double-negative (CD4- CD8-) alpha beta and gamma delta T cells from human patients with cutaneous leishmaniasis. Infect Immun (2006) 1.15
Trypanosoma cruzi infection induces differential modulation of costimulatory molecules and cytokines by monocytes and T cells from patients with indeterminate and cardiac Chagas' disease. Infect Immun (2007) 1.14
Interleukin 17 production among patients with American cutaneous leishmaniasis. J Infect Dis (2009) 1.12
Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease. Mem Inst Oswaldo Cruz (2009) 1.11
The CCR5Δ32 polymorphism as a pre-eclampsia susceptibility marker: an evaluation in Brazilian women. Arch Gynecol Obstet (2014) 1.08
A functional interleukin-1 beta gene polymorphism is associated with chronic periodontitis in a sample of Brazilian individuals. J Periodontal Res (2005) 1.02
Changed gluten immunity in celiac disease by Necator americanus provides new insights into autoimmunity. Int J Parasitol (2013) 0.96
High interleukin 17 expression is correlated with better cardiac function in human Chagas disease. J Infect Dis (2012) 0.95
Immunoregulatory mechanisms and CD4-CD8- (double negative) T cell subpopulations in human cutaneous leishmaniasis: a balancing act between protection and pathology. Int Immunopharmacol (2008) 0.95
Cutaneous leishmaniasis during pregnancy: exuberant lesions and potential fetal complications. Clin Infect Dis (2007) 0.93
Trypanosoma cruzi-induced activation of functionally distinct αβ and γδ CD4- CD8- T cells in individuals with polar forms of Chagas' disease. Infect Immun (2010) 0.92
IgG isotype profile is correlated with cardiomegaly in Beagle dogs infected with distinct Trypanosoma cruzi strains. Vet Immunol Immunopathol (2008) 0.92
Type I IFNs stimulate nitric oxide production and resistance to Trypanosoma cruzi infection. J Immunol (2006) 0.91
Oxidant generation by single infected monocytes after short-term fluorescence labeling of a protozoan parasite. Infect Immun (2006) 0.91
Norepinephrine, dopamine and dexamethasone modulate discrete leukocyte subpopulations and cytokine profiles from human PBMC. J Neuroimmunol (2005) 0.90
Interleukin-1 gene polymorphisms and toxoplasmic retinochoroiditis. Mol Vis (2008) 0.89
Insights into CD4+ memory T cells following Leishmania infection. Trends Parasitol (2005) 0.88
Polarized Th2 like cells, in the absence of Th0 cells, are responsible for lymphocyte produced IL-4 in high IgE-producer schistosomiasis patients. BMC Immunol (2002) 0.88
Infection-induced respiratory burst in BALB/c macrophages kills Leishmania guyanensis amastigotes through apoptosis: possible involvement in resistance to cutaneous leishmaniasis. Microbes Infect (2005) 0.85
Endogenous IL-4 and IFN-gamma are essential for expression of Th2, but not Th1 cytokine message during the early differentiation of human CD4+ T helper cells. Hum Immunol (2004) 0.84
A sensitive flow cytometric methodology for studying the binding of L. chagasi to canine peritoneal macrophages. BMC Infect Dis (2005) 0.83
Adhesion molecule expression patterns indicate activation and recruitment of CD4+ T cells from the lymph node to the peripheral blood of early cutaneous leishmaniasis patients. Immunol Lett (2003) 0.83
Schistosoma mansoni infection alters co-stimulatory molecule expression and cell activation in asthma. Microbes Infect (2008) 0.83
Peripheral toxicity in crack cocaine use disorders. Neurosci Lett (2013) 0.83
Interleukin-10 gene polymorphism (-1082G/A) is associated with toxoplasmic retinochoroiditis. Invest Ophthalmol Vis Sci (2008) 0.82
Acupuncture is effective to attenuate stress and stimulate lymphocyte proliferation in the elderly. Neurosci Lett (2010) 0.82
Implications of cytokine gene polymorphisms on the orchestration of the immune response: lessons learned from oral diseases. Cytokine Growth Factor Rev (2009) 0.81
Characterization of alpha-enolase as an interferon-alpha 2 alpha 1 regulated gene. Front Biosci (2005) 0.81
Interleukin-6 gene polymorphism (-174 G/C) is associated with toxoplasmic retinochoroiditis. Acta Ophthalmol (2013) 0.80
Immunoregulatory and Effector Activities in Human Cutaneous and Mucosal Leishmaniasis: Understanding Mechanisms of Pathology. Drug Dev Res (2011) 0.78
Trypanosoma cruzi: populations bearing opposite virulence induce differential expansion of circulating CD3+CD4-CD8- T cells and cytokine serum levels in young and adult rats. Exp Parasitol (2007) 0.78
Clinical aspects of Chagas disease and implications for novel therapies. Drug Dev Res (2011) 0.77
Low levels of vasoactive intestinal peptide are associated with Chagas disease cardiomyopathy. Hum Immunol (2013) 0.76
Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review. Biogerontology (2013) 0.76
Relationship between cytokine levels in serum and gingival crevicular fluid (GCF) in pregnant women. Cytokine (2012) 0.76
Evaluation of alternative reporter genes for the yeast two-hybrid system. Genet Mol Res (2003) 0.76
The mammalian fetus, a naturally occurring graft. Med Hypotheses (2011) 0.75
Transcription factor STAT1 gene polymorphism is associated with the development of severe forms of periodontal disease. Inflamm Res (2013) 0.75
Monocyte dysfunction in Sydenham's chorea patients. Hum Immunol (2010) 0.75