| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors.
|
Farmaco
|
2003
|
0.88
|
|
2
|
Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity.
|
Farmaco
|
2005
|
0.88
|
|
3
|
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
|
J Med Chem
|
2001
|
0.83
|
|
4
|
Investigation on QSAR and binding mode of a new class of human rhinovirus-14 inhibitors by CoMFA and docking experiments.
|
Bioorg Med Chem
|
1996
|
0.80
|
|
5
|
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5-methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class.
|
Chirality
|
2001
|
0.78
|
|
6
|
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors.
|
J Med Chem
|
2001
|
0.78
|
|
7
|
Molecular modeling of azole antifungal agents active against Candida albicans. 1. A comparative molecular field analysis study.
|
J Med Chem
|
1996
|
0.77
|
|
8
|
[[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity.
|
J Med Chem
|
1995
|
0.75
|
|
9
|
Antifungal agents, II: Synthesis and antifungal activities of aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane derivatives with unsaturated chains.
|
Arch Pharm (Weinheim)
|
1993
|
0.75
|
|
10
|
Antifungal agents. 7. Dichlorophenylpyrrylimidazolylmethane derivatives: synthesis and antifungal activities.
|
Farmaco
|
1994
|
0.75
|