Published in Nat Neurosci on April 01, 2003
Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain (2009) 7.11
Ectopic discharge in Abeta afferents as a source of neuropathic pain. Exp Brain Res (2009) 1.91
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy. Mol Pain (2011) 1.66
Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res (2012) 1.24
Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord. J Comp Neurol (2006) 0.99
Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts. Biomaterials (2011) 0.96
Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse. Mol Pain (2011) 0.94
Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia. FEBS J (2011) 0.93
EphBs: an integral link between synaptic function and synaptopathies. Trends Neurosci (2012) 0.93
EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia. Neuroscience (2008) 0.91
Targeted mutation of EphB1 receptor prevents development of neuropathic hyperalgesia and physical dependence on morphine in mice. Mol Pain (2008) 0.88
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain. Mol Pain (2010) 0.85
Presenilin 1 affects focal adhesion site formation and cell force generation via c-Src transcriptional and posttranslational regulation. J Biol Chem (2009) 0.80
Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor. Eur J Pain (2014) 0.80
Expression and activation of ephexin is altered after spinal cord injury. Dev Neurobiol (2011) 0.79
Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain. PLoS One (2013) 0.78
The Role of Ephs and Ephrins in Memory Formation. Int J Neuropsychopharmacol (2016) 0.75
Ephrin-B2 expression in the proprioceptive sensory system. Neurosci Lett (2013) 0.75
Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain. PLoS Biol (2017) 0.75
Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature (2002) 8.22
Role of the immune system in chronic pain. Nat Rev Neurosci (2005) 4.10
Neurotrophins: mediators and modulators of pain. Annu Rev Neurosci (2006) 3.44
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP. J Physiol (2005) 2.25
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. Proc Natl Acad Sci U S A (2007) 2.17
Spinal cord repair strategies: why do they work? Nat Rev Neurosci (2006) 2.00
CCL2 is a key mediator of microglia activation in neuropathic pain states. Eur J Pain (2008) 1.85
Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. J Neurosci (2005) 1.82
Pathophysiology of peripheral neuropathic pain: immune cells and molecules. Anesth Analg (2007) 1.73
Role of spinal microglia in rat models of peripheral nerve injury and inflammation. Eur J Pain (2006) 1.70
Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice. Exp Neurol (2005) 1.65
Heritability of responses to painful stimuli in women: a classical twin study. Brain (2007) 1.59
Acid-induced pain and its modulation in humans. J Neurosci (2004) 1.58
P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. J Neurosci (2010) 1.55
Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice. J Neurosci (2004) 1.55
Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation. J Neurochem (2006) 1.45
Effects of Etanercept and Minocycline in a rat model of spinal cord injury. Eur J Pain (2008) 1.43
Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis. Pain (2013) 1.40
P2X receptors and their role in female idiopathic detrusor instability. J Urol (2002) 1.36
Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. J Neurosci (2008) 1.34
Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord. Nat Neurosci (2005) 1.31
Chondroitinase ABC-mediated plasticity of spinal sensory function. J Neurosci (2008) 1.27
Neuregulin-ErbB signaling promotes microglial proliferation and chemotaxis contributing to microgliosis and pain after peripheral nerve injury. J Neurosci (2010) 1.26
Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain. Brain (2007) 1.25
Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain. Mol Cell Neurosci (2006) 1.24
Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Mol Cell Neurosci (2002) 1.22
Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy. Pain (2007) 1.21
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain (2006) 1.21
BDNF: a neuromodulator in nociceptive pathways? Brain Res Brain Res Rev (2002) 1.21
Chronic pain: emerging evidence for the involvement of epigenetics. Neuron (2012) 1.21
The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury. J Neurosci (2008) 1.17
Neurotrophin-3-mediated regeneration and recovery of proprioception following dorsal rhizotomy. Mol Cell Neurosci (2002) 1.15
ATF3 expression in L4 dorsal root ganglion neurons after L5 spinal nerve transection. Eur J Neurosci (2006) 1.15
Modulation of acid-sensing ion channel activity by nitric oxide. J Neurosci (2007) 1.15
CXCL5 mediates UVB irradiation-induced pain. Sci Transl Med (2011) 1.15
Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain. Eur J Pain (2008) 1.12
Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway. Glia (2011) 1.11
Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord. Eur J Neurosci (2004) 1.10
Release of BDNF and GABA in the dorsal horn of neuropathic rats. Eur J Neurosci (2003) 1.10
NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury. Eur J Neurosci (2004) 1.09
Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats. Pain (2005) 1.06
Ultraviolet-B induced inflammation of human skin: characterisation and comparison with traditional models of hyperalgesia. Eur J Pain (2008) 1.06
Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain (2010) 1.06
Microchannel electrodes for recording and stimulation: in vitro evaluation. IEEE Trans Biomed Eng (2009) 1.05
The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn. Mol Cell Neurosci (2003) 1.04
Genes contributing to pain sensitivity in the normal population: an exome sequencing study. PLoS Genet (2012) 1.04
Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages. J Neurosci (2011) 1.04
Activity-dependent phosphorylation of Akt/PKB in adult DRG neurons. Eur J Neurosci (2005) 1.03
Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats. Eur J Pain (2008) 1.02
Increased spinal cord phosphorylation of extracellular signal-regulated kinases mediates micturition overactivity in rats with chronic bladder inflammation. Eur J Neurosci (2005) 1.02
Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. Arthritis Rheum (2011) 1.01
Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test. Eur J Pain (2008) 1.00
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance. J Neurosci (2009) 1.00
Artemin has potent neurotrophic actions on injured C-fibres. J Peripher Nerv Syst (2006) 0.99
Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury. J Neurosci (2012) 0.98
TrkB expression and phospho-ERK activation by brain-derived neurotrophic factor in rat spinothalamic tract neurons. J Comp Neurol (2005) 0.97
Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy. J Pharmacol Exp Ther (2008) 0.97
Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury. J Comp Neurol (2009) 0.97
Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord. Hum Mol Genet (2006) 0.96
Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation. Pain (2010) 0.96
Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF. Mol Ther (2006) 0.96
Identification of perineal sensory neurons activated by innocuous heat. J Comp Neurol (2010) 0.96
A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat. Mol Pain (2014) 0.95
Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat. PLoS Biol (2010) 0.95
Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat. Mol Pain (2011) 0.93
Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain. Mol Ther (2011) 0.92
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain. Pain (2013) 0.91
BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn. Mol Cell Neurosci (2002) 0.90
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination. Brain (2013) 0.90
A peripheral nervous system actin-binding protein regulates neurite outgrowth. Eur J Neurosci (2002) 0.90
Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo. Eur J Neurosci (2003) 0.90
Ultraviolet radiation-induced inflammation as a model for cutaneous hyperalgesia. J Invest Dermatol (2004) 0.89
Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin. J Peripher Nerv Syst (2002) 0.87
The activation of the ERK pathway contributes to the spinal c-fos expression observed after noxious bladder stimulation. Somatosens Mot Res (2007) 0.87
Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia. Genesis (2006) 0.87
Delayed treatment with chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury. Exp Neurol (2011) 0.87
Understanding chronic inflammatory and neuropathic pain. Ann N Y Acad Sci (2012) 0.85
A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo. J Neural Eng (2012) 0.85
Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord. J Neurosci (2010) 0.85
Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barré syndrome. Neurosci Lett (2008) 0.85
Chronic cough and pain: Janus faces in sensory neurobiology? Pulm Pharmacol Ther (2013) 0.85
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain. Mol Pain (2010) 0.85
Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. J Clin Invest (2014) 0.85
Microchannels as axonal amplifiers. IEEE Trans Biomed Eng (2008) 0.84
Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord. Regen Med (2007) 0.84
PainNetworks: a web-based resource for the visualisation of pain-related genes in the context of their network associations. Pain (2013) 0.83
Chemokines as peripheral pain mediators. Neurosci Lett (2013) 0.82