Published in Diabetologia on January 01, 2003
Genetic epidemiology of diabetes. J Clin Invest (2005) 2.53
Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action. PLoS Biol (2003) 2.13
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proc Natl Acad Sci U S A (2005) 1.59
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program. Diabetes (2007) 1.51
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility. Am J Hum Genet (2003) 1.24
Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes. Hum Genet (2004) 1.10
Pharmacogenetics of Anti-Diabetes Drugs. Pharmaceuticals (Basel) (2010) 0.97
Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population. PLoS One (2010) 0.92
The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity. Diabetes (2012) 0.90
Population specific impact of genetic variants in KCNJ11 gene to type 2 diabetes: a case-control and meta-analysis study. PLoS One (2014) 0.84
Modeling K,ATP--dependent excitability in pancreatic islets. Biophys J (2014) 0.81
Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes. Endocr Rev (2016) 0.78
Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type 2 Diabetes in Childhood and Adolescence in Taiwan. Int J Endocrinol (2014) 0.78
Replication of KCNJ11 (p.E23K) and ABCC8 (p.S1369A) Association in Russian Diabetes Mellitus 2 Type Cohort and Meta-Analysis. PLoS One (2015) 0.77
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care (1997) 23.95
Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature (2001) 23.49
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature (2000) 5.55
The nucleotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E coli K12. Nucleic Acids Res (1981) 5.52
Crystal structure of TFIID TATA-box binding protein. Nature (1992) 4.85
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell (2001) 4.58
Adenosine diphosphate as an intracellular regulator of insulin secretion. Science (1996) 4.42
Obesity-related glomerulopathy: an emerging epidemic. Kidney Int (2001) 3.98
An assessment of radical prostatectomy. Time trends, geographic variation, and outcomes. The Prostate Patient Outcomes Research Team. JAMA (1993) 3.65
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). Nat Genet (1998) 3.65
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem (2000) 3.44
Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia. J Clin Invest (2001) 3.29
Phenotypic diversity and ecosystem functioning in changing environments: a theoretical framework. Proc Natl Acad Sci U S A (2001) 3.13
The stationary-phase sigma factor sigma S (RpoS) is required for a sustained acid tolerance response in virulent Salmonella typhimurium. Mol Microbiol (1995) 3.11
Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest (1992) 3.05
Evidence for increased recombination near the human insulin gene: implication for disease association studies. Proc Natl Acad Sci U S A (1986) 2.96
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol (1994) 2.95
Signal transduction by the TCR for antigen. Curr Opin Immunol (2000) 2.87
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol (1996) 2.78
Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration. Cell (1997) 2.71
The dynamics of cocirculating influenza strains conferring partial cross-immunity. J Math Biol (1997) 2.69
A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science (1995) 2.68
Patient-reported complications and follow-up treatment after radical prostatectomy. The National Medicare Experience: 1988-1990 (updated June 1993). Urology (1993) 2.66
Linkage of type 2 diabetes to the glucokinase gene. Lancet (1992) 2.64
Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins (2005) 2.59
Familial hyperinsulinism caused by an activating glucokinase mutation. N Engl J Med (1998) 2.57
Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene (1994) 2.47
Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med (1995) 2.44
Shotgun optical maps of the whole Escherichia coli O157:H7 genome. Genome Res (2001) 2.43
Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature (1997) 2.41
Familial hyperinsulinism with apparent autosomal dominant inheritance: clinical and genetic differences from the autosomal recessive variant. J Pediatr (1998) 2.33
Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa. J Virol (1995) 2.25
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene (2001) 2.25
Vasopressin administration facilitates fluid removal during hemodialysis. Kidney Int (2006) 2.23
PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Nucleic Acids Res (2001) 2.23
Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes (2001) 2.19
The clinical value of the upper gastrointestinal tract roentgenogram series. Arch Intern Med (1980) 2.14
Assessment of function in routine clinical practice: description of the COOP Chart method and preliminary findings. J Chronic Dis (1987) 2.14
A robust method for the detection of linkage in familial disease. Am J Hum Genet (1978) 2.10
NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees. Am J Med Genet (1998) 2.09
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis. Diabetologia (2005) 2.08
Completely diverted tube ileostomy compared with loop ileostomy for protection of low colorectal anastomosis: a pilot study. Colorectal Dis (2014) 2.06
Beyond synexpression relationships: local clustering of time-shifted and inverted gene expression profiles identifies new, biologically relevant interactions. J Mol Biol (2001) 2.03
An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science (2000) 2.03
Evaluation of three hollow-fiber membrane oxygenators without integrated arterial filters for neonatal cardiopulmonary bypass. Perfusion (2011) 2.02
Thromboprophylaxis rates in US medical centers: success or failure? J Thromb Haemost (2007) 2.02
Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med (1991) 2.00
The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa). J Virol (1996) 1.97
Glucose transporter protein content and glucose transport capacity in rat skeletal muscles. Am J Physiol (1990) 1.91
Injecting drug use and HIV infection in southwest China. AIDS (1994) 1.91
The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell (1996) 1.88
A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes (1997) 1.86
Hemoglobin desaturation after succinylcholine-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers. Anesthesiology (2001) 1.84
Mild hypothermia via selective head cooling as neuroprotective therapy in term neonates with perinatal asphyxia: an experience from a single neonatal intensive care unit. J Perinatol (2006) 1.79
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci U S A (1998) 1.76
Mutations in the sulonylurea receptor gene are associated with familial hyperinsulinism in Ashkenazi Jews. Hum Mol Genet (1996) 1.76
Mitochondrial COII sequences and modern human origins. Mol Biol Evol (1993) 1.73
Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene (2010) 1.72
Family cell lines available for research. Am J Hum Genet (1990) 1.72
Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium. Am J Med Genet (1998) 1.72
Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev (1995) 1.69
US of soft-tissue foreign bodies and associated complications with surgical correlation. Radiographics (2001) 1.66
A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca(2+)-permeable channel in the yeast vacuolar membrane. Proc Natl Acad Sci U S A (2001) 1.63
Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells. Gynecol Oncol (2000) 1.61
Multiple restriction fragment length polymorphisms at the insulin receptor locus: a highly informative marker for linkage analysis. Proc Natl Acad Sci U S A (1986) 1.59
Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy. Diabetes (1998) 1.59
Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication. Hum Mol Genet (1998) 1.58
Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet (2000) 1.57
Functional neuroanatomy of spatial working memory in children. Dev Psychol (2000) 1.57
Genetic analysis of glucose tolerance in inbred mouse strains. Evidence for polygenic control. Diabetes (1988) 1.56
Renal aspergilloma: an unusual cause of infection in a patient with the acquired immunodeficiency syndrome. Am J Med (1992) 1.56
Death as a complication of peripherally inserted central catheters in neonates. J Pediatr (2001) 1.56
Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J Clin Invest (1998) 1.55
Glucokinase as pancreatic beta cell glucose sensor and diabetes gene. J Clin Invest (1993) 1.55
Medium for Screening Leuconostoc oenos Strains Defective in Malolactic Fermentation. Appl Environ Microbiol (1989) 1.54
Insulin biosynthesis. I. On the mechanism of glucose stimulation. J Biol Chem (1972) 1.54
Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. Oncogene (2010) 1.53
Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women. Brain Behav Immun (2008) 1.53
Functional health status levels of primary care patients. JAMA (1983) 1.52
A genome screen of multiplex sibships with prostate cancer. Am J Hum Genet (2000) 1.51
Myocardial injury and left ventricular performance after subarachnoid hemorrhage. Stroke (1999) 1.51
Diabetes mellitus and optic atrophy: a study of Wolfram syndrome in the Lebanese population. J Clin Endocrinol Metab (2004) 1.51
Change in failure stress on the southern san andreas fault system caused by the 1992 magnitude = 7.4 landers earthquake. Science (1992) 1.51
African Americans and participation in clinical trials: differences in beliefs and attitudes by gender. Contemp Clin Trials (2006) 1.51
Percutaneous trans-hepatic cholangioscopy and lithotripsy in the treatment of intrahepatic stones: a study with 5 year follow-up. Gastrointest Endosc (1995) 1.50
Incidence and temporal pattern of hospital readmissions for patients with atrial fibrillation. Curr Med Res Opin (2009) 1.50
Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. Br J Cancer (2005) 1.48
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. Oncogene (2000) 1.47
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase. J Med Chem (1999) 1.47
Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis. Anticancer Res (2000) 1.46
Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia (1998) 1.46
Selective internal radiation therapy with intra-arterial iodine-131-Lipiodol in inoperable hepatocellular carcinoma. J Nucl Med (1994) 1.45
Polymorphism in the 5' flanking region of the human insulin gene: a genetic marker for non-insulin-dependent diabetes. N Engl J Med (1983) 1.44
Role of data aggregation in biosurveillance detection strategies with applications from ESSENCE. MMWR Morb Mortal Wkly Rep (2004) 1.42
Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice. Int J Cancer (2000) 1.42
Subinsular vascular lesions: an analysis of 119 consecutive autopsied brains. Eur J Neurol (2007) 1.40
A novel, model-based insulin and nutrition delivery controller for glycemic regulation in critically ill patients. Diabetes Technol Ther (2006) 1.40