Apoptosis in Huntington's disease.

Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease. Neuropsychopharmacology (2011) 1.66

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nat Chem Biol (2010) 1.62

Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder. Pharmacol Rev (2013) 1.52

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders. Pharmacol Ther (2010) 1.39

Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice. Neuroscience (2006) 1.23

Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders. Curr Alzheimer Res (2012) 1.19

Functional imaging in Huntington's disease. Exp Neurol (2009) 1.08

Induction of striatal pre- and postsynaptic damage by methamphetamine requires the dopamine receptors. Synapse (2005) 1.08

Autophagy and neuronal cell death in neurological disorders. Cold Spring Harb Perspect Biol (2012) 1.08

Modeling Huntington's disease with induced pluripotent stem cells. Mol Cell Neurosci (2013) 0.94

Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease. Cell Stem Cell (2013) 0.91

Genetic and environmental factors in the pathogenesis of Huntington's disease. Neurogenetics (2004) 0.90

The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease. Toxicol Appl Pharmacol (2010) 0.89

Neuroprotective action of lithium in disorders of the central nervous system. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2011) 0.87

Therapeutic approaches to preventing cell death in Huntington disease. Prog Neurobiol (2012) 0.84

Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI). J Biol Chem (2011) 0.84

Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis. Neurobiol Dis (2006) 0.83

Treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in Huntington's disease rats. J Exerc Rehabil (2015) 0.82

Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease. J Neurol (2006) 0.81

Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. J Psychiatry Neurosci (2004) 0.80

Replacement of huntingtin exon 1 by trans-splicing. Cell Mol Life Sci (2012) 0.80

BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin. Eur J Neurosci (2010) 0.79

Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. Int J Biol Sci (2010) 0.78

PARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington's Disease. PLoS One (2015) 0.77

Neural Differentiation of Human Pluripotent Stem Cells for Nontherapeutic Applications: Toxicology, Pharmacology, and In Vitro Disease Modeling. Stem Cells Int (2015) 0.77

Oral treatment with the herbal formula B401 protects against aging-dependent neurodegeneration by attenuating oxidative stress and apoptosis in the brain of R6/2 mice. Clin Interv Aging (2015) 0.76

Curcumin modulates cell death and is protective in Huntington's disease model. Sci Rep (2016) 0.75

Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis. PLoS Genet (2017) 0.75