1
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Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.
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Am J Hum Genet
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2004
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5.02
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2
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Drug addiction: the neurobiology of behaviour gone awry.
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Nat Rev Neurosci
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2004
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3.13
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3
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Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference.
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Behav Genet
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2002
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2.56
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4
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Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.
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Proc Natl Acad Sci U S A
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2002
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2.47
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5
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Quantifying the risks associated with exceeding recommended drinking limits.
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Alcohol Clin Exp Res
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2005
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2.44
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6
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The neuroscience of addiction.
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Nat Neurosci
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2005
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2.24
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7
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The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption.
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PLoS Med
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2009
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2.20
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8
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Determinants of alcohol use and abuse: Impact of quantity and frequency patterns on liver disease.
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Hepatology
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2007
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2.20
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9
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A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence.
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Am J Med Genet A
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2004
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1.88
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Protective effects of the alcohol dehydrogenase-ADH1B allele in children exposed to alcohol during pregnancy.
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J Pediatr
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2006
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1.78
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11
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Neuroscience networks: data-sharing in an information age.
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PLoS Biol
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2003
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1.74
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12
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A prospective study of risk drinking: at risk for what?
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Drug Alcohol Depend
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2008
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1.72
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13
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Drugs and alcohol: treating and preventing abuse, addiction and their medical consequences.
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Pharmacol Ther
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2005
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1.58
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14
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Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.
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Neuropsychopharmacology
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2005
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1.43
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15
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Transitions in and out of alcohol use disorders: their associations with conditional changes in quality of life over a 3-year follow-up interval.
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Alcohol Alcohol
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2008
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1.41
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16
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Research funding: the view from NIH.
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Am J Psychiatry
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2006
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1.38
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17
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Genetic polymorphisms: impact on the risk of fetal alcohol spectrum disorders.
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Birth Defects Res A Clin Mol Teratol
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2005
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1.38
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18
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Alcohol and ADH2 in Israel: Ashkenazis, Sephardics, and recent Russian immigrants.
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Am J Psychiatry
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2002
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Prenatal alcohol exposure: advancing knowledge through international collaborations.
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Alcohol Clin Exp Res
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Effects of repeated alcohol deprivations on operant ethanol self-administration by alcohol-preferring (P) rats.
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Neuropsychopharmacology
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2003
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1.31
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Microdialysis of dopamine in the nucleus accumbens of alcohol-preferring (P) rats during anticipation and operant self-administration of ethanol.
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Alcohol Clin Exp Res
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2002
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1.31
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22
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Errors in assessing DSM-IV substance use disorders.
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Arch Gen Psychiatry
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2007
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Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Periadolescent exposure.
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Alcohol Clin Exp Res
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2002
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1.26
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24
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Impact of age at first drink on stress-reactive drinking.
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Alcohol Clin Exp Res
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2007
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1.26
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25
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Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats.
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J Pharmacol Exp Ther
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1.23
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Alcohol-related olfactory cues activate the nucleus accumbens and ventral tegmental area in high-risk drinkers: preliminary findings.
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Alcohol Clin Exp Res
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2004
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1.22
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Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: II. Adult exposure.
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Alcohol Clin Exp Res
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2002
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1.22
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28
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A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake.
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Alcohol Clin Exp Res
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2003
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1.21
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Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
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Psychopharmacology (Berl)
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2010
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1.20
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alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats.
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Proc Natl Acad Sci U S A
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2003
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1.18
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31
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Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence.
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Alcohol Clin Exp Res
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2003
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1.15
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32
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Gender differences in the relationship of internalizing and externalizing psychopathology to alcohol dependence: likelihood, expression and course.
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Drug Alcohol Depend
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1.15
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33
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Recent drinking history: association with family history of alcoholism and the acute response to alcohol during a 60 mg% clamp.
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J Stud Alcohol
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2002
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1.13
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The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring rats.
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Pharmacol Biochem Behav
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2002
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1.12
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35
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Neurobehavioral consequences of prenatal alcohol exposure: an international perspective.
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Alcohol Clin Exp Res
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1.10
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36
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Comparison of intracranial self-administration of ethanol within the posterior ventral tegmental area between alcohol-preferring and Wistar rats.
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Alcohol Clin Exp Res
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2004
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1.09
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37
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The reinforcing properties of salsolinol in the ventral tegmental area: evidence for regional heterogeneity and the involvement of serotonin and dopamine.
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Alcohol Clin Exp Res
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2007
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1.07
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38
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Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat.
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Alcohol Clin Exp Res
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2009
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1.06
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39
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High- and low-alcohol-preferring mice show differences in conditioned taste aversion to alcohol.
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Alcohol Clin Exp Res
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1.06
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40
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Moderate alcohol exposure compromises neural tube midline development in prenatal brain.
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Brain Res Dev Brain Res
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2003
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41
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Role of GABRA2 in moderating subjective responses to alcohol.
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Alcohol Clin Exp Res
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42
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Prolonged increase in the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol following repeated exposure to cycles of ethanol access and deprivation.
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J Pharmacol Exp Ther
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43
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Intravenous ethanol infusions can mimic the time course of breath alcohol concentrations following oral alcohol administration in healthy volunteers.
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Alcohol Clin Exp Res
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Alcohol limits in older people.
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45
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Alcohol dependence symptoms and alcohol dehydrogenase 2 polymorphism: Israeli Ashkenazis, Sephardics, and recent Russian immigrants.
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Alcohol Clin Exp Res
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2002
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46
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Chronic ethanol drinking by alcohol-preferring rats increases the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol.
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Alcohol Clin Exp Res
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2005
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1.01
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47
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Limits to growth: why neuroscience needs large-scale science.
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Nat Neurosci
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Effects of concurrent access to a single concentration or multiple concentrations of ethanol on ethanol intake by periadolescent high-alcohol-drinking rats.
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Alcohol
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2004
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49
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Influence of ADH1B polymorphism on alcohol use and its subjective effects in a Jewish population.
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Am J Med Genet
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2002
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Subjective intoxication in response to alcohol challenge: heritability and covariation with personality, breath alcohol level, and drinking history.
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Alcohol Clin Exp Res
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2003
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1.00
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51
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Treatment use and barriers among adolescents with prescription opioid use disorders.
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Addict Behav
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52
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Identification of QTLs influencing alcohol preference in the High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) mouse lines.
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Behav Genet
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Behavioral profiling of multiple pairs of rats selectively bred for high and low alcohol intake using the MCSF test.
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Addict Biol
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54
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A pilot study of alcohol exposure and pharmacokinetics in women with or without children with fetal alcohol syndrome.
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Alcohol Alcohol
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2004
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55
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The role of acetaldehyde in the central effects of ethanol.
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Alcohol Clin Exp Res
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56
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Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats.
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Alcohol Clin Exp Res
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Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part I: adult brain growth.
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Alcohol Clin Exp Res
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58
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Saccadic eye movements are associated with a family history of alcoholism at baseline and after exposure to alcohol.
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Alcohol Clin Exp Res
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Effects of long-term episodic access to ethanol on the expression of an alcohol deprivation effect in low alcohol-consuming rats.
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Alcohol Clin Exp Res
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Using the cue-availability paradigm to assess cue reactivity.
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Alcohol Clin Exp Res
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JAMA
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Innate differences in protein expression in the nucleus accumbens and hippocampus of inbred alcohol-preferring and -nonpreferring rats.
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Proteomics
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Alcohol Clin Exp Res
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Alcohol research: past, present, and future.
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Ann N Y Acad Sci
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Using electronic health records data to assess comorbidities of substance use and psychiatric diagnoses and treatment settings among adults.
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J Psychiatr Res
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Glutathione S-transferase 8-8 expression is lower in alcohol-preferring than in alcohol-nonpreferring rats.
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Alcohol Clin Exp Res
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67
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Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part II: effects of voluntary chronic alcohol consumption.
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Alcohol Clin Exp Res
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68
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Binge drinking in Jewish and non-Jewish white college students.
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Alcohol Clin Exp Res
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Reduced neuropeptide Y mRNA expression in the central nucleus of amygdala of alcohol preferring (P) rats: its potential involvement in alcohol preference and anxiety.
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Brain Res
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Alcohol Clin Exp Res
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71
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Dopamine and serotonin content in select brain regions of weanling and adult alcohol drinking rat lines.
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Pharmacol Biochem Behav
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Alleles of alcohol and acetaldehyde metabolism genes modulate susceptibility to oesophageal cancer from alcohol consumption.
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Hum Genomics
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Changes in liver protein abundance in inbred alcohol-preferring rats due to chronic alcohol exposure, as measured through a proteomics approach.
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Proteomics
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74
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Deviations in brain early serotonergic development as a result of fetal alcohol exposure.
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Neurotox Res
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2002
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75
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Genomewide SNP screen to detect quantitative trait loci for alcohol preference in the high alcohol preferring and low alcohol preferring mice.
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Alcohol Clin Exp Res
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0.84
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76
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AA and ANA rats exhibit the R100Q mutation in the GABAA receptor alpha 6 subunit.
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Alcohol
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77
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Linkage for platelet monoamine oxidase (MAO) activity: results from a replication sample.
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Alcohol Clin Exp Res
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2002
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78
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Confirmation of alcohol preference quantitative trait loci in the replicate high alcohol drinking and low alcohol drinking rat lines.
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Psychiatr Genet
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A critical evaluation of influence of ethanol and diet on salsolinol enantiomers in humans and rats.
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Alcohol Clin Exp Res
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Effects of acute administration of ethanol on cerebral glucose utilization in adult alcohol-preferring and alcohol-nonpreferring rats.
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Alcohol
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Nat Neurosci
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Involvement of acetaldehyde in alcohol addiction.
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Alcohol Clin Exp Res
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Episodic heavy drinking, problem drinking and injuries - results of the WHO/NIAAA collaborative emergency room study in South Korea.
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Alcohol
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Ethanol effects on local cerebral glucose utilization in high-alcohol-drinking and low-alcohol-drinking rats.
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Alcohol
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Heart rate and motor-activating effects of orally self-administered ethanol in alcohol-preferring (P) rats.
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Alcohol Clin Exp Res
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Regional CNS densities of serotonin 1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pups.
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Pharmacol Biochem Behav
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Genetic propensities to increase ethanol intake in response to stress: studies with selectively bred swim test susceptible (SUS), alcohol-preferring (P), and non-preferring (NP) lines of rats.
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Psychopharmacology (Berl)
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2011
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Local cerebral glucose utilization after relapse in ethanol drinking in alcohol-preferring (P) rats.
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Alcohol
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Maintaining steady state arterial alcohol levels in rats by using a physiologically based pharmacokinetic model.
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Alcohol
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From herbal roots to synthetic medicines: a historical perspective.
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Alcohol Clin Exp Res
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Treatments for alcohol dependence: rethinking the role of comorbidity and clinical subtypes.
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Am J Psychiatry
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What is addiction?
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Alcohol Res Health
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Sedative and motor-impairing effects of neuropeptide Y and ethanol in selectively bred P and NP rats.
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Pharmacol Biochem Behav
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Metabolic products of [2-(13) C]ethanol in the rat brain after chronic ethanol exposure.
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J Neurochem
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Calcitonin gene-related peptide (CGRP) levels and alcohol.
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Int J Neuropsychopharmacol
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Autonomic activation associated with ethanol self-administration in adult female P rats.
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Pharmacol Biochem Behav
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Response to: "Rescuing the NIH before it is too late".
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J Clin Invest
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In memory of James D. Beard 7-21-1937 to 10-7-2014.
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Alcohol Clin Exp Res
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Impulsivity and addiction: a tribute to Henri Begleiter.
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ScientificWorldJournal
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Underage drinking: understanding and reducing risk in the context of human development. Foreword.
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Pediatrics
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