Keith A Hruska

Author PubWeight™ 50.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J Am Soc Nephrol 2005 2.27
2 The mechanism of phosphorus as a cardiovascular risk factor in CKD. J Am Soc Nephrol 2008 1.99
3 Vascular calcification in chronic kidney disease. Am J Kidney Dis 2004 1.81
4 Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. J Am Soc Nephrol 2005 1.54
5 Impaired micro-RNA pathways diminish osteoclast differentiation and function. J Biol Chem 2008 1.53
6 Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes. J Clin Endocrinol Metab 2012 1.52
7 RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury. Kidney Int 2011 1.51
8 A microRNA expression signature of osteoclastogenesis. Blood 2011 1.49
9 BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. J Am Soc Nephrol 2003 1.45
10 Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus. Am J Nephrol 2015 1.42
11 Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors. J Biol Chem 2004 1.40
12 CKD accelerates development of neointimal hyperplasia in arteriovenous fistulas. J Am Soc Nephrol 2009 1.40
13 Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy. J Am Soc Nephrol 2006 1.37
14 Vitamin D receptor activators can protect against vascular calcification. J Am Soc Nephrol 2008 1.35
15 Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy. Kidney Int 2003 1.29
16 Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus. Circ Cardiovasc Genet 2012 1.22
17 Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model. J Am Soc Nephrol 2004 1.10
18 Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells. J Cell Biochem 2003 1.07
19 PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility. J Biol Chem 2002 1.06
20 Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes. J Bone Miner Res 2011 1.06
21 Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease. Am J Nephrol 2013 1.03
22 Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells. J Bone Miner Res 2004 1.01
23 Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts. J Biol Chem 2003 0.99
24 The BMP-7-Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury. J Urol 2011 0.99
25 Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study. J Bone Miner Res 2009 0.96
26 The urinary response to an oral oxalate load in recurrent calcium stone formers. J Urol 2003 0.94
27 The pathogenesis of osteodystrophy after renal transplantation as detected by early alterations in bone remodeling. Kidney Int 2003 0.93
28 Bone morphogenetic protein-7 delays podocyte injury due to high glucose. Nephrol Dial Transplant 2007 0.93
29 Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7. Kidney Int 2002 0.93
30 Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast. J Bone Miner Res 2003 0.92
31 Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease. Curr Opin Nephrol Hypertens 2004 0.91
32 Vascular smooth muscle cells in the pathogenesis of vascular calcification. Circ Res 2009 0.88
33 Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study. J Clin Endocrinol Metab 2013 0.88
34 Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption. BMC Cell Biol 2004 0.86
35 Bone morphogenetic protein-7: an anti-fibrotic morphogenetic protein with therapeutic importance in renal disease. Curr Opin Nephrol Hypertens 2002 0.85
36 Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells. J Cell Biochem 2003 0.84
37 Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study. BMC Nephrol 2012 0.84
38 Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis. J Cell Biochem 2013 0.84
39 Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease. Pediatr Nephrol 2014 0.82
40 Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study. J Clin Endocrinol Metab 2013 0.82
41 Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries. Am J Physiol Renal Physiol 2011 0.81
42 In vivo transplantation of neonatal ovine neocartilage allografts: determining the effectiveness of tissue transglutaminase. J Knee Surg 2005 0.81
43 Left ventricular mass progression despite stable blood pressure and kidney function in stage 3 chronic kidney disease. Am J Nephrol 2014 0.81
44 Expression of DGCR8-dependent microRNAs is indispensable for osteoclastic development and bone-resorbing activity. J Cell Biochem 2014 0.81
45 The Kidney-Vascular-Bone Axis in the Chronic Kidney Disease-Mineral Bone Disorder. Transplantation 2016 0.78
46 New discoveries in the pathogenesis of renal osteodystrophy. J Bone Miner Metab 2006 0.75