Toshio Heike

Author PubWeight™ 131.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 2009 9.01
2 NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood 2002 7.78
3 Generation of pluripotent stem cells from neonatal mouse testis. Cell 2004 3.95
4 Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model. Blood 2003 2.53
5 Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2. J Immunol 2009 2.44
6 Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. Blood 2004 2.32
7 Reduced Numbers and Proapoptotic Features of Mucosal-associated Invariant T Cells as a Characteristic Finding in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis 2015 2.13
8 Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells. Blood 2007 2.00
9 Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients. Blood 2007 1.69
10 High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study. Arthritis Rheum 2011 1.61
11 Somatic mosaicism of CIAS1 in a patient with chronic infantile neurologic, cutaneous, articular syndrome. Arthritis Rheum 2005 1.59
12 The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun 2009 1.45
13 Limited response to CRH stimulation tests at 2 weeks of age in preterm infants born at less than 30 weeks of gestational age. Clin Endocrinol (Oxf) 2013 1.44
14 Birth order effect on childhood food allergy. Pediatr Allergy Immunol 2012 1.41
15 Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes. J Biol Chem 2005 1.40
16 Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells. FASEB J 2010 1.38
17 Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis. Arthritis Rheum 2009 1.33
18 Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovasc Res 2010 1.21
19 Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. Exp Cell Res 2007 1.20
20 Detection of base substitution-type somatic mosaicism of the NLRP3 gene with >99.9% statistical confidence by massively parallel sequencing. DNA Res 2012 1.16
21 Generation of transplantable, functional satellite-like cells from mouse embryonic stem cells. FASEB J 2009 1.15
22 Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rgammanull mice. Virology 2009 1.11
23 Selective development of myogenic mesenchymal cells from human embryonic and induced pluripotent stem cells. PLoS One 2012 1.10
24 Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers. J Neurosci Res 2005 1.07
25 Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro. Development 2004 1.06
26 X-linked ectodermal dysplasia and immunodeficiency caused by reversion mosaicism of NEMO reveals a critical role for NEMO in human T-cell development and/or survival. Blood 2004 1.05
27 Side population cells contribute to the genesis of human endometrium. Fertil Steril 2008 1.03
28 Impaired neutrophil maturation in truncated murine G-CSF receptor-transgenic mice. Blood 2003 1.03
29 A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS One 2011 1.02
30 Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. Blood 2012 1.01
31 Autosomal dominant anhidrotic ectodermal dysplasia with immunodeficiency caused by a novel NFKBIA mutation, p.Ser36Tyr, presents with mild ectodermal dysplasia and non-infectious systemic inflammation. J Clin Immunol 2013 1.00
32 Diagnosis and treatment in anhidrotic ectodermal dysplasia with immunodeficiency. Allergol Int 2012 1.00
33 Generation of cardiac and endothelial cells from neonatal mouse testis-derived multipotent germline stem cells. Stem Cells 2007 1.00
34 Novel method for efficient production of multipotential hematopoietic progenitors from human embryonic stem cells. Int J Hematol 2007 1.00
35 Flk1(+) cardiac stem/progenitor cells derived from embryonic stem cells improve cardiac function in a dilated cardiomyopathy mouse model. Cardiovasc Res 2007 1.00
36 Long-term extensive expansion of mouse hepatic stem/progenitor cells in a novel serum-free culture system. Gastroenterology 2005 0.98
37 Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion. FASEB J 2007 0.98
38 Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration. J Neuropathol Exp Neurol 2010 0.98
39 Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body. Blood 2003 0.97
40 Tool-use learning induces BDNF expression in a selective portion of monkey anterior parietal cortex. Brain Res Mol Brain Res 2002 0.96
41 Neutrophil differentiation from human-induced pluripotent stem cells. J Cell Physiol 2011 0.93
42 Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial disease. Hum Mutat 2012 0.93
43 Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors. J Cell Physiol 2009 0.92
44 Safety and efficacy of canakinumab in Japanese patients with phenotypes of cryopyrin-associated periodic syndrome as established in the first open-label, phase-3 pivotal study (24-week results). Clin Exp Rheumatol 2013 0.92
45 Bone marrow engraftment but limited expansion of hematopoietic cells from multipotent germline stem cells derived from neonatal mouse testis. Exp Hematol 2009 0.92
46 Robust and highly-efficient differentiation of functional monocytic cells from human pluripotent stem cells under serum- and feeder cell-free conditions. PLoS One 2013 0.91
47 Nationwide survey of patients with primary immunodeficiency diseases in Japan. J Clin Immunol 2011 0.91
48 A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells. Proc Natl Acad Sci U S A 2006 0.90
49 Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause Nagashima-type palmoplantar keratosis. Am J Hum Genet 2013 0.90
50 Identification of cardiac stem cells with FLK1, CD31, and VE-cadherin expression during embryonic stem cell differentiation. FASEB J 2005 0.90
51 Identification and characterization of hemoangiogenic progenitors during cynomolgus monkey embryonic stem cell differentiation. Stem Cells 2006 0.90
52 SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis. J Allergy Clin Immunol 2005 0.90
53 Multiple reversions of an IL2RG mutation restore T cell function in an X-linked severe combined immunodeficiency patient. J Clin Immunol 2012 0.89
54 Tool-use learning selectively induces expression of brain-derived neurotrophic factor, its receptor trkB, and neurotrophin 3 in the intraparietal multisensorycortex of monkeys. Brain Res Cogn Brain Res 2002 0.89
55 Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein. Blood 2011 0.88
56 Sequential analysis of alpha- and beta-globin gene expression during erythropoietic differentiation from primate embryonic stem cells. Stem Cells 2006 0.88
57 Direct development of functionally mature tryptase/chymase double-positive connective tissue-type mast cells from primate embryonic stem cells. Stem Cells 2007 0.88
58 Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis. PLoS One 2011 0.88
59 Frequent somatic mosaicism of NEMO in T cells of patients with X-linked anhidrotic ectodermal dysplasia with immunodeficiency. Blood 2012 0.87
60 Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality. Mech Dev 2008 0.87
61 Long-term culture of postnatal mouse hepatic stem/progenitor cells and their relative developmental hierarchy. Stem Cells 2007 0.85
62 Changing prevalence and severity of childhood allergic diseases in kyoto, Japan, from 1996 to 2006. Allergol Int 2009 0.85
63 Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes. PLoS One 2010 0.85
64 Direct visualization of transplanted hematopoietic cell reconstitution in intact mouse organs indicates the presence of a niche. Exp Hematol 2003 0.85
65 Ring/marker chromosome derived from chromosome 7 in childhood acute megakaryoblastic leukemia with monosomy 7. Int J Hematol 2010 0.85
66 Disseminated BCG infection mimicking metastatic nasopharyngeal carcinoma in an immunodeficient child with a novel hypomorphic NEMO mutation. J Clin Immunol 2011 0.85
67 Successful treatment with infliximab for inflammatory colitis in a patient with X-linked anhidrotic ectodermal dysplasia with immunodeficiency. J Clin Immunol 2011 0.84
68 Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis. Haematologica 2013 0.84
69 Obesity and the prevalence of allergic diseases in schoolchildren. Pediatr Allergy Immunol 2008 0.84
70 The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation. Int Immunol 2011 0.84
71 Heterozygous TREX1 p.Asp18Asn mutation can cause variable neurological symptoms in a family with Aicardi-Goutieres syndrome/familial chilblain lupus. Rheumatology (Oxford) 2012 0.84
72 alpha4-Integrin(+) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells. Blood 2006 0.83
73 The clinical utility of genetic testing for t(8;16)(p11;p13) in congenital acute myeloid leukemia. J Pediatr Hematol Oncol 2014 0.83
74 A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study. Rheumatology (Oxford) 2013 0.83
75 Differential requirement for the CD40-CD154 costimulatory pathway during Th cell priming by CD8 alpha+ and CD8 alpha- murine dendritic cell subsets. J Immunol 2004 0.83
76 Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes. J Cell Physiol 2011 0.83
77 Sca-1+ endothelial cells (SPECs) reside in the portal area of the liver and contribute to rapid recovery from acute liver disease. Biochem Biophys Res Commun 2007 0.83
78 Breastfeeding and the prevalence of allergic diseases in schoolchildren: Does reverse causation matter? Pediatr Allergy Immunol 2010 0.83
79 Patient with neonatal-onset chronic hepatitis presenting with mevalonate kinase deficiency with a novel MVK gene mutation. Mod Rheumatol 2011 0.83
80 Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev Dyn 2010 0.82
81 Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice. Dig Dis Sci 2012 0.82
82 Cortical muscle control of spontaneous movements in human neonates. Eur J Neurosci 2014 0.82
83 Efficient assay for evaluating human thrombopoiesis using NOD/SCID mice transplanted with cord blood CD34+ cells. Eur J Haematol 2006 0.82
84 Role of bone marrow-derived progenitor cells in cuff-induced vascular injury in mice. Arterioscler Thromb Vasc Biol 2004 0.81
85 The effect of past food avoidance due to allergic symptoms on the growth of children at school age. Allergol Int 2010 0.81
86 Hyperthyrotropinemia at 2 weeks of age indicates thyroid dysfunction and predicts the occurrence of delayed elevation of thyrotropin in very low birth weight infants. Clin Endocrinol (Oxf) 2012 0.81
87 Diagnostic value of salivary cortisol in the CRH stimulation test in premature infants. J Clin Endocrinol Metab 2012 0.81
88 Limited ability of antigen-specific Th1 responses to inhibit Th2 cell development in vivo. J Immunol 2005 0.80
89 HOX decoy peptide enhances the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells/hematopoietic progenitor cells. Stem Cells 2006 0.80
90 Salivary biomarkers are not suitable for pain assessment in newborns. Early Hum Dev 2013 0.80
91 MEFV Variants in Patients with PFAPA Syndrome in Japan. Open Rheumatol J 2013 0.80
92 Familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. J Pediatr 2010 0.80
93 Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway. Arthritis Rheumatol 2015 0.79
94 Allergic status of schoolchildren with food allergy to eggs, milk or wheat in infancy. Pediatr Allergy Immunol 2009 0.79
95 Paroxysmal gaze deviations as the sole manifestation of occipital lobe epilepsy. Seizure 2013 0.79
96 Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia-telangiectasia-like disorder: potential diagnostic clues? Am J Med Genet A 2014 0.79
97 [Changes in Japanese cedar sensitization rates of Japanese allergic children during the last 15 years]. Arerugi 2004 0.79
98 MRI gadolinium enhancement precedes neuroradiological findings in acute necrotizing encephalopathy. Brain Dev 2012 0.79
99 A case of early-onset sarcoidosis with a six-base deletion in the NOD2 gene. Rheumatology (Oxford) 2009 0.78
100 Guidance on the use of canakinumab in patients with cryopyrin-associated periodic syndrome in Japan. Mod Rheumatol 2012 0.78
101 Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors. Mol Cell Neurosci 2010 0.78
102 Two different roles of purified CD45+c-Kit+Sca-1+Lin- cells after transplantation in muscles. Stem Cells 2005 0.78
103 Derivation of engraftable myogenic precursors from murine ES/iPS cells and generation of disease-specific iPS cells from patients with Duchenne muscular dystrophy (DMD) and other diseases. Rinsho Shinkeigaku 2010 0.78
104 Plasma homocysteine, methionine and S-adenosylhomocysteine levels following high-dose methotrexate treatment in pediatric patients with acute lymphoblastic leukemia or Burkitt lymphoma: association with hepatotoxicity. Leuk Lymphoma 2013 0.78
105 Effect of eczema on the association between season of birth and food allergy in Japanese children. Pediatr Int 2012 0.77
106 [Heterogeneity of HLH pathophysiology and treatment strategies]. Rinsho Ketsueki 2015 0.77
107 [Epileptic encephalopathy associated with human herpes virus 6 (HHV-6) encephalitis after the second cord blood transplantation in a patient with pediatric acute lymphoblastic leukemia]. Rinsho Ketsueki 2014 0.77
108 High prevalence of severe circulatory complications with diazoxide in premature infants. Neonatology 2014 0.77
109 Neonatal mouse testis-derived multipotent germline stem cells improve the cardiac function of acute ischemic heart mouse model. Biochem Biophys Res Commun 2010 0.76
110 Hematopoietic stem cell transplantation with reduced intensity conditioning from a family haploidentical donor in an infant with familial hemophagocytic lymphohistocytosis. Int J Hematol 2011 0.76
111 Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome. Blood 2013 0.76
112 Reply. Inflamm Bowel Dis 2015 0.75
113 Total and low-density lipoprotein cholesterol levels are associated with atopy in schoolchildren. J Pediatr 2010 0.75
114 Primary immunodeficiency and related diseases. Allergol Int 2012 0.75
115 Obvious optic disc swelling in a patient with cryopyrin-associated periodic syndrome. Clin Ophthalmol 2013 0.75
116 Development of CMV retinitis in an antigenemia-negative infant after cord blood transplantation. Rinsho Ketsueki 2015 0.75
117 [Hyperimmunoglobulinemia D and periodic fever syndrome]. Nihon Rinsho Meneki Gakkai Kaishi 2011 0.75
118 Effective cardiac resynchronization therapy for an adolescent patient with dilated cardiomyopathy seven years after mitral valve replacement and septal anterior ventricular exclusion. J Cardiothorac Surg 2010 0.75
119 Munc13-4 deficiency with CD5 downregulation on activated CD8+ T cells. Pediatr Int 2014 0.75
120 Expression profile analysis of aorta-gonad-mesonephros region-derived stromal cells reveals genes that regulate hematopoiesis. Biochem Biophys Res Commun 2008 0.75
121 Pediatric idiopathic TTP diagnosed with decreased ADAMTS13 activity. Pediatr Int 2012 0.75
122 Chronic immune-mediated axonal polyneuropathy following umbilical cord blood transplant for childhood-onset cerebral adrenoleukodystrophy. Pediatr Transplant 2012 0.75
123 [An approach to the patients with cryopyrin-associated periodic syndrome (CAPS) : a new biologic response modifier, canakinumab]. Nihon Rinsho Meneki Gakkai Kaishi 2012 0.75
124 Long-term outcome of sirolimus-eluting stent implantation for left main coronary artery stenosis in infancy. Pediatr Cardiol 2010 0.75
125 [Efficacy and tolerability of topiramate, lamotrigine, and levetiracetam in children with refractory epilepsy]. No To Hattatsu 2015 0.75
126 Long-term efficacy of bevacizumab and irinotecan in recurrent pediatric glioblastoma. Pediatr Int 2015 0.75
127 Perforation of enteric duplication during chemotherapy for osteosarcoma. Pediatr Int 2014 0.75
128 [Diagnosis and consultation rates of allergic diseases in 11-year old schoolchildren, and usefulness of allergy screening test at school]. Arerugi 2012 0.75
129 Acute lymphoblastic leukemia in a girl with Wilson's disease. Pediatr Int 2014 0.75
130 Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays. Int J Oncol 2002 0.75
131 Good response to chemotherapy spares irradiation for extrarenal rhabdoid tumor conferring better activities of daily living. J Pediatr Hematol Oncol 2015 0.75
132 Efficacy of Ifosfamide-Cisplatin-Etoposide (ICE) Chemotherapy for a CNS Germinoma in a Child With Down Syndrome. J Pediatr Hematol Oncol 2016 0.75
133 [Comparative study on the efficacy and safety of continuous versus twice-daily 3-hour infusion of cyclosporine A in pediatric hematopoietic stem cell transplantation]. Rinsho Ketsueki 2012 0.75
134 Successful treatment of refractory donor lymphocyte infusion-induced immune-mediated pancytopenia with rituximab. Pediatr Blood Cancer 2010 0.75
135 Gastric ulcer and gastroenteritis caused by Epstein-Barr virus during immunosuppressive therapy for a child with systemic juvenile idiopathic arthritis. Rheumatology (Oxford) 2012 0.75
136 [Utility of endoscopic ultrasound-guided fine needle aspiration for diagnosis of Burkitt lymphoma in two pediatric cases]. Rinsho Ketsueki 2013 0.75
137 The NOD/Shi-scid/IL-2Rγ(null) mice xenograft model recapitulates anaplastic large cell lymphoma dissemination to the bladder. Leuk Lymphoma 2014 0.75
138 Rituximab-combination chemotherapy achieves a 10th cycle of remission for Burkitt's lymphoma. Pediatr Int 2015 0.75
139 [Changes in food allergen sensitization rates of Japanese allergic children during the last 15 years]. Arerugi 2004 0.75
140 [A girl with dyslexia suspected to have Irlen syndrome, completely relieved by wearing tinted lenses]. No To Hattatsu 2015 0.75