Published in Clin Pharmacol Ther on June 01, 1976
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity. Neuropharmacology (2016) 0.83
The pharmacokinetics of R- and S-tocainide in patients with acute ventricular arrhythmias. Br J Clin Pharmacol (1986) 0.82
Prophylaxis against ventricular arrhythmias in suspected acute myocardial infarction: a comparison of tocainide and disopyramide. Br J Clin Pharmacol (1984) 0.75
Tocainide protein binding in normal volunteers and trauma patients. Br J Clin Pharmacol (1982) 0.75
Perinatal events associated with maternal smoking during pregnancy. Am J Epidemiol (1976) 2.49
Dopamine in the treatment of hypotension and shock. N Engl J Med (1966) 1.77
Low birth weight and neonatal mortality rate related to maternal smoking and socioeconomic status. Am J Obstet Gynecol (1971) 1.73
The interrelationship of maternal smoking and increased perinatal mortality with other risk factors. Further analysis of the Ontario Perinatal Mortality Study, 1960-1961. Am J Epidemiol (1974) 1.63
Respiratory effects on household exposures to tobacco smoke and gas cooking. Am Rev Respir Dis (1981) 1.58
Food, splanchnic blood flow, and bioavailability of drugs subject to first-pass metabolism. Clin Pharmacol Ther (1978) 1.51
Effect of food on hepatic blood flow: implications in the "food effect" phenomenon. Clin Pharmacol Ther (1983) 1.43
Maternal smoking, pregnancy complications, and perinatal mortality. Am J Obstet Gynecol (1977) 1.36
How does maternal smoking affect birth weight and maternal weight gain? Evidence from the Ontario Perinatal Mortality Study. Am J Obstet Gynecol (1978) 1.25
Alpha1-acid glycoprotein concentration and protein binding in trauma. Clin Pharmacol Ther (1982) 1.23
Maternal cigarette smoking and perinatal mortality. Am J Epidemiol (1972) 1.18
Comparison of chromatographic and spectrophotometric analysis of indocyanine green in plasma following administration of multiple doses to humans. J Pharm Sci (1982) 1.18
Individualization of phenytoin dosage regimens. Clin Pharmacol Ther (1977) 1.17
Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations. Osteoporos Int (2006) 1.17
Influence of food on the presystemic metabolism of drugs. Pharmacol Ther (1988) 1.12
Effects of dopamine on renal function and hemodynamics in the dog. J Pharmacol Exp Ther (1967) 1.12
Hypothesis: the role of the lung in stomach carcinogenesis. Am Rev Respir Dis (1980) 1.08
Role of risk factors in complications of diabetes mellitus. Am J Epidemiol (1980) 1.04
Free drug concentration monitoring in clinical practice. Rationale and current status. Clin Pharmacokinet (1987) 1.04
Evaluation of mumps vaccine given after exposure to mumps, with special reference to the exposed adult. Pediatrics (1966) 1.02
Letter: Absolute drug bioavailability: approximation without comparison to parenteral dose for compounds exhibiting perturbable renal clearance. J Pharm Sci (1974) 1.02
Absorption kinetics of procainamide in humans. J Pharm Sci (1977) 1.02
Effect of food on lidocaine kinetics: mechanism of food-related alteration in high intrinsic clearance drug elimination. Clin Pharmacol Ther (1981) 1.01
Oral absorption and disposition kinetics of lidocaine hydrochloride in dogs. J Pharmacol Exp Ther (1970) 1.00
Factors influencing serum protein binding of lidocaine in humans. Anesth Analg (1981) 0.99
Alcohol consumption and airway obstruction. Am Rev Respir Dis (1980) 0.97
New antiarrhythmic agents. 1. Primary alpha-amino anilides. J Med Chem (1979) 0.96
Effect of carbohydrates on estimated hepatic blood flow. Clin Pharmacol Ther (1984) 0.95
Determination of hydralazine and its metabolites by gas chromatography-mass spectrometry. J Chromatogr (1976) 0.92
Factors affecting quinidine protein binding in humans. J Pharm Sci (1984) 0.89
Pulmonary disease and drug kinetics. Clin Pharmacokinet (1978) 0.88
Breast-feeding and smoking. Lancet (1979) 0.85
Effect of cimetidine on the pharmacokinetics and pharmacodynamics of quinidine. Am J Cardiol (1983) 0.85
Reactions of 2,2-dimethylaziridine-type alkylating agents in biological systems II: comparative pharmacokinetics in dogs. J Pharm Sci (1975) 0.84
Displacement of lidocaine from serum alpha 1-acid glycoprotein binding sites by basic drugs. Eur J Clin Pharmacol (1983) 0.84
Multiple factors in airways obstruction. Chest (1980) 0.83
Clinical pharmacokinetics of pethidine: 1982. Clin Pharmacokinet (1983) 0.83
The pharmacokinetics of meperidine in acute trauma patients. J Trauma (1986) 0.83
Long-term effects of prenatal x-ray of human females. III. Mortality and morbidity. Am J Epidemiol (1981) 0.82
Tocainide conjugation in humans: novel biotransformation pathway for a primary amine. J Pharm Sci (1980) 0.82
Effect of beta-adrenergic blockade on beat-to-beat response to Valsalva manoeuvre. Br Heart J (1974) 0.82
Effect of smoking on binding of lidocaine to human serum proteins. J Pharm Sci (1980) 0.82
The effect of -adrenergic blockade on cardiac responses to orthostatic stress. Am Heart J (1972) 0.82
Indocyanine green: pharmacokinetics in the rabbit and relevant studies of its stability and purity. J Pharm Sci (1986) 0.81
Birth weight-specific rates as a bias in the effects of smoking and other perinatal hazards. Obstet Gynecol (1981) 0.81
Nonlinear pharmacokinetics of indocyanine green in the rabbit and rat. J Pharmacokinet Biopharm (1980) 0.81
Antiarrhythmic effectiveness of intramuscular lidocaine: influence of different injection sites. J Clin Pharmacol (1974) 0.81
Lack of effect of smoking on the metabolism and pharmacokinetics of quinidine in patients. Br J Clin Pharmacol (1987) 0.81
Is ABH nonsecretor status a risk factor for obstructive lung disease? Am J Epidemiol (1980) 0.81
Effect of food coadministration on 5-aminosalicylic acid oral suspension bioavailability. Clin Pharmacol Ther (1990) 0.80
Development of a bacteria-independent model of the multiple organ failure syndrome. Arch Surg (1989) 0.80
Simultaneous quantitation of disopyramide and its mono-dealkylated metabolite in human plasma by fused-silica capillary gas chromatography using nitrogen-phosphorus specific detection. J Chromatogr (1984) 0.80
Visual testing for readiness to drive after stroke: a multicenter study. Am J Phys Med Rehabil (2000) 0.79
Abstracts of the 6th FECS Conference 1998 Lectures. Environ Sci Pollut Res Int (1998) 0.79
Lack of effect of treatment with human recombinant-tumour necrosis factor (HrTNF) on the binding of quinidine to alpha 1-acid glycoprotein (AGP). Br J Clin Pharmacol (1989) 0.79
Tocainide kinetics and metabolism: effects of phenobarbital and substrates of glucuronyl transferase. Clin Pharmacol Ther (1980) 0.79
Mechanisms of nonlinear disposition kinetics of sulfamethazine. Clin Pharmacol Ther (1979) 0.79
Applicability of capillary gas liquid chromatography to the measurement of free fraction of disopyramide in human plasma. Res Commun Chem Pathol Pharmacol (1985) 0.79
Multiple bolus technique for lidocaine administration in acute ischemic heart disease. II. Treatment of refractory ventricular arrhythmias and the pharmacokinetic significance of severe left ventricular failure. J Am Coll Cardiol (1983) 0.78
Dose-dependent pharmacokinetic behavior of lidocaine in the conscious dog. Res Commun Chem Pathol Pharmacol (1978) 0.78
Effects of hydralazine, nitroglycerin, and food on estimated hepatic blood flow. Clin Pharmacol Ther (1985) 0.77
High-dose omeprazole: use of a multiple-dose study design to assess bioequivalence and accuracy of CYP2C19 phenotyping. Ther Drug Monit (1999) 0.77
Sex ratio of children born to mothers who had been exposed to x-rays in utero. Johns Hopkins Med J (1968) 0.77
Endogenous accumulation products and serum protein binding in uremia. J Lab Clin Med (1981) 0.77
Investigation of the effects of prenatal x-ray exposure of human oogonia and oocytes as measured by later reproductive performance. Am J Epidemiol (1969) 0.77
Ampicillin vs. Penicillin for in utero therapy. Infect Dis Obstet Gynecol (1996) 0.77
Plasma clearance and tissue distribution of partially thiolated polycytidylic acid and its degradation products in rodents. Cancer Res (1984) 0.77
The effects of maternal smoking in pregnancy. Core J Pediatr (1978) 0.76
Multiple bolus technique for lidocaine administration during the first hours of an acute myocardial infarction. Am J Cardiol (1978) 0.76
Tocainide protein binding in normal volunteers and trauma patients. Br J Clin Pharmacol (1982) 0.75
Effects of (plus or minus)-propranolol, (plus or minus)-,(plus)-, and (minus)-alprenolol on unanaesthetized dogs with ventricular arrhythmias resulting from coronary artery ligation. Br J Pharmacol (1970) 0.75
Disopyramide pharmacokinetics and metabolism: effect of inducers. Br J Clin Pharmacol (1987) 0.75
Glutathione S-transferase in human endometrium: quantitation and interindividual variability in isoform content. Gynecol Obstet Invest (1999) 0.75
Long-term effects of prenatal x-ray of human females. I. Reproductive experience. Am J Epidemiol (1981) 0.75
The use of dopamine in the treatment of hypotension and shock after myocardial infarction or cardiac surgery. Am Heart J (1966) 0.75
Acute cardiovascular, antiarrhythmic and toxic effects of tetrodotoxin (TTX) in unanesthetized dogs. Toxicol Appl Pharmacol (1972) 0.75
The acute antiarrhythmic and toxic effects in mice and dogs of 2-ethylamino-2',6-'acetoxylidine (L-86), a metabolite of lidocaine. J Pharmacol Exp Ther (1971) 0.75
Evaluation of etidocaine, a new local anesthetic agent, with a modified bilateral ulnar-nerve-block-technique. Anesthesiology (1974) 0.75
Cigarette smoking, infant birth weight, and perinatal mortality rates. Am J Obstet Gynecol (1973) 0.75
Assay of tocainide in blood by high-pressure liquid chromatography. J Pharm Sci (1978) 0.75
The high voltage paper electrophoresis of kinin peptides K9, K10, and K11. Biochim Biophys Acta (1971) 0.75
Possible effects of x-ray exposure during fetal life on the subsequent reproductive performance of human females. Am J Epidemiol (1973) 0.75
Experimental epidural anaesthesia in the cat with lignocaine and amethocaine. Br J Anaesth (1969) 0.75
Definition of perinatal mortality. Lancet (1977) 0.75
Anti-arrhythmic and serum free fatty acid lowering effects of 5-fluoro-nicotinyl alcohol following experimentally induced myocardial infarction in the dog. Cardiovasc Res (1974) 0.75
Evaluation of tests for the measurement of previous mumps infection and analysis of mumps experience by blood group. Am J Epidemiol (1966) 0.75
Blood levels of lidocaine following subcutaneous administration prior to cardiac catheterization. Am Heart J (1974) 0.75
The effect of propranolol and the dextro and laevo isomers of H 56-28 upon ouabain-induced ventricular tachycardia in unanaesthetized dogs. Acta Pharmacol Toxicol (Copenh) (1967) 0.75
Long-term effects of prenatal x-ray of human females. II. Growth and development. Am J Epidemiol (1981) 0.75
Antiarrhythmic effects in dogs of lidocaine administered orally and intravenously. Am Heart J (1972) 0.75
Pharmacokinetics of diltiazem and propranolol when administered alone and in combination. Biopharm Drug Dispos (1991) 0.75
Indirect sympathomimetic activity of Recosen, a commercial heart extract. Cardiologia (1966) 0.75