Published in Neuroreport on April 15, 2003
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Hum Mol Genet (2011) 1.72
Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep. JAMA Neurol (2013) 1.37
ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice. Mol Neurodegener (2013) 0.90
The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice. PLoS One (2011) 0.85
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet (2002) 4.01
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity (2004) 3.25
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat Genet (2008) 2.13
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nat Genet (2005) 2.13
Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study. Arch Gen Psychiatry (2004) 2.07
Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells in vivo by genetically manipulated expression of tetanus neurotoxin light chain. J Neurosci (2003) 1.85
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc Natl Acad Sci U S A (2002) 1.66
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease. J Neurosci (2004) 1.63
Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta. J Neurochem (2002) 1.45
jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression. Dev Cell (2003) 1.44
Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice. J Biol Chem (2002) 1.29
Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells. J Biol Chem (2002) 1.23
Generation of reelin-positive marginal zone cells from the caudomedial wall of telencephalic vesicles. J Neurosci (2004) 1.23
Germ cells are essential for sexual dimorphism in the medaka gonad. Proc Natl Acad Sci U S A (2007) 1.22
Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. J Neurochem (2005) 1.20
Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation. J Neurosci (2003) 1.16
Phenotypic characterization of transgenic mice overexpressing neuregulin-1. PLoS One (2010) 1.16
A critical time window of Sry action in gonadal sex determination in mice. Development (2008) 1.14
Activin in the brain modulates anxiety-related behavior and adult neurogenesis. PLoS One (2008) 1.14
Identification of amino-terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration. Ann Neurol (2004) 1.13
Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades. Biochem Biophys Res Commun (2005) 1.08
p25/cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons. J Neurochem (2007) 1.07
Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord. J Neurosci (2005) 1.06
Cadherin-8 is required for the first relay synapses to receive functional inputs from primary sensory afferents for cold sensation. J Neurosci (2007) 1.06
Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression. Immunity (2008) 1.05
Lithium-induced activation of Akt and CaM kinase II contributes to its neuroprotective action in a rat microsphere embolism model. Brain Res (2006) 1.05
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice. Am J Pathol (2005) 1.05
Mechanism of asymmetric ovarian development in chick embryos. Development (2008) 1.04
Successful cryopreservation of mouse ovaries by vitrification. Biol Reprod (2003) 1.03
Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice. Am J Pathol (2003) 1.02
Stress-induced hyperphosphorylation of tau in the mouse brain. FEBS Lett (2003) 1.02
Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury. Nat Commun (2013) 1.00
Activin plays a key role in the maintenance of long-term memory and late-LTP. Learn Mem (2010) 0.97
Critical function of T cell death-associated gene 8 in glucocorticoid-induced thymocyte apoptosis. Int Immunol (2003) 0.95
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem J (2010) 0.95
The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice. Biol Reprod (2003) 0.93
Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS Lett (2007) 0.93
Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model. Hum Mol Genet (2004) 0.92
Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta. Acta Crystallogr D Biol Crystallogr (2004) 0.91
Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation. Am J Pathol (2006) 0.91
An alternatively spliced form of glycogen synthase kinase-3beta is targeted to growing neurites and growth cones. Mol Cell Neurosci (2009) 0.90
Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development. J Biol Chem (2006) 0.90
A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse. PLoS One (2011) 0.89
Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: implications of autophagy promotion. Neurobiol Dis (2012) 0.89
Phosphorylated alpha-synuclein in normal mouse brain. FEBS Lett (2004) 0.89
Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport (2002) 0.87
Impaired arterial pressure regulation during exercise due to enhanced muscular vasodilatation in calponin knockout mice. J Physiol (2003) 0.86
In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta. J Biol Chem (2002) 0.86
Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice. J Cereb Blood Flow Metab (2004) 0.86
Reduced pain sensitivity in mice lacking latexin, an inhibitor of metallocarboxypeptidases. Brain Res (2006) 0.86
Phosphorylation of FTDP-17 mutant tau by cyclin-dependent kinase 5 complexed with p35, p25, or p39. J Biol Chem (2005) 0.85
Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells. PLoS One (2013) 0.85
Importance of forkhead transcription factor Fkhl18 for development of testicular vasculature. Mol Reprod Dev (2008) 0.85
Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons. Mol Neurodegener (2007) 0.84
Regulation of immunological disorders by invariant Vα19-Jα33 TCR-bearing cells. Immunobiology (2010) 0.84
The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice. Mol Brain (2010) 0.84
Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. J Biol Chem (2013) 0.83
Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E. Neurosci Lett (2004) 0.83
Marked improvement of fertility of cryopreserved C57BL/6J mouse sperm by depletion of Ca2+ in medium. J Reprod Dev (2009) 0.83
Different immunoreactivities of the microtubule-binding region of tau and its molecular basis in brains from patients with Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol (2003) 0.83
Early lethality of beta-1,4-galactosyltransferase V-mutant mice by growth retardation. Biochem Biophys Res Commun (2008) 0.83
Morphogenetic roles of perlecan in the tooth enamel organ: an analysis of overexpression using transgenic mice. Matrix Biol (2011) 0.83
Clonally expanding thymocytes having lineage capability in gamma-ray-induced mouse atrophic thymus. Int J Radiat Oncol Biol Phys (2010) 0.82
Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice. Neurobiol Dis (2011) 0.82
Motor discoordination of transgenic mice overexpressing a microtubule destabilizer, stathmin, specifically in Purkinje cells. Neurosci Res (2007) 0.82
Biochemical and ultrastructural study of neurofibrillary tangles in amyotrophic lateral sclerosis/parkinsonism-dementia complex in the Kii peninsula of Japan. J Neuropathol Exp Neurol (2003) 0.82
Validity of the Hfm transgenic mouse as a model for hemifacial microsomia. Cleft Palate Craniofac J (2002) 0.81
Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice. J Neuropathol Exp Neurol (2003) 0.81
Accelerated Abeta aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain. FEBS Lett (2004) 0.80
Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads. Endocrinology (2010) 0.80
Point mutation in syntaxin-1A causes abnormal vesicle recycling, behaviors, and short term plasticity. J Biol Chem (2013) 0.79
Exon 3 insert of tau protein in neurodegenerative diseases. Acta Neuropathol (2005) 0.79
Localization of NK1.1(+) invariant Valpha19 TCR(+) cells in the liver with potential to promptly respond to TCR stimulation. Immunol Lett (2008) 0.79
Effect of Pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant Tau. J Biol Chem (2009) 0.79
Tau phosphorylation in the mouse brain during aversive conditioning. Neurochem Int (2007) 0.78
Accelerated modification of the zona pellucida is the primary cause of decreased fertilizability of oocytes in the 129 inbred mouse strain. Zygote (2010) 0.78
Cardiac abnormalities cause early lethality of jumonji mutant mice. Biochem Biophys Res Commun (2004) 0.77
Full reconstitution of hematopoietic system by murine umbilical cord blood. Transplantation (2003) 0.77
Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations. Amyloid (2013) 0.77
Neuronal and glial tau pathology in early frontotemporal lobar degeneration-tau, Pick's disease subtype. J Neurol Sci (2010) 0.77
Production and characterization of monoclonal antibodies to mouse germ cells. Hybridoma (Larchmt) (2010) 0.77
Tail-suspended mice lacking calponin H1 experience decreased bone loss. Tohoku J Exp Med (2010) 0.76
Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains. J Neurochem (2007) 0.76
Successful pregnancies after transplantation of frozen-thawed mouse ovaries into chimeric mice that received lethal-dose radiation. Fertil Steril (2006) 0.76
Establishment of a genome-wide and quantitative protocol for assessment of transcriptional activity at human retrotransposon L1 antisense promoters. Genes Genet Syst (2017) 0.75
Novel axonal distribution of neurofilament-H phosphorylated at the glycogen synthase kinase 3beta-phosphorylation site in its E-segment. J Neurosci Res (2009) 0.75
Trp53 affects the developmental anomaly of clefts of the palate in irradiated mouse embryos but not clefts of the lip with or without the palate. Radiat Res (2006) 0.75
Expression of SV40 T antigen gene in the oligodendroglia induced primitive neuroectodermal tumor-like tumors in the mouse brain. Congenit Anom (Kyoto) (2004) 0.75
MuSC is involved in regulating axonal fasciculation of mouse primary vestibular afferents. Eur J Neurosci (2003) 0.75
Ataxia and male sterility (AMS) mouse. A new genetic variant exhibiting degeneration and loss of cerebellar Purkinje cells and spermatic cells. Pathol Int (2003) 0.75
[Sex differentiation of the mammalian gonad]. Tanpakushitsu Kakusan Koso (2004) 0.75
[Sex differentiation of the gonads and regulation of gene expression]. Nihon Rinsho (2004) 0.75