Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors.

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Published in Tissue Antigens on March 01, 2003

Authors

C M Cabrera1, P Jiménez, T Cabrera, C Esparza, F Ruiz-Cabello, F Garrido

Author Affiliations

1: Departamento de Análisis Clínicos, Hospital Universitario Virgen de las Nieves, Universidad de Granada, 18014 Granada, Spain.

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