| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone.
|
Endocr Rev
|
2003
|
1.60
|
|
2
|
Crystal structure of human dehydroepiandrosterone sulphotransferase in complex with substrate.
|
Biochem J
|
2002
|
1.23
|
|
3
|
17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
|
Mol Endocrinol
|
2010
|
1.05
|
|
4
|
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.
|
Mol Endocrinol
|
2004
|
1.05
|
|
5
|
Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation.
|
J Biol Chem
|
2004
|
1.04
|
|
6
|
Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex.
|
J Biol Chem
|
2003
|
1.03
|
|
7
|
The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation.
|
J Biol Chem
|
2009
|
0.99
|
|
8
|
Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
|
J Biol Chem
|
2006
|
0.95
|
|
9
|
Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase.
|
FASEB J
|
2002
|
0.94
|
|
10
|
Comparison of functional proteomic analyses of human breast cancer cell lines T47D and MCF7.
|
PLoS One
|
2012
|
0.93
|
|
11
|
Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance.
|
Proteins
|
2006
|
0.92
|
|
12
|
Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet.
|
Antimicrob Agents Chemother
|
2011
|
0.92
|
|
13
|
17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration.
|
Breast Cancer Res
|
2012
|
0.87
|
|
14
|
Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy.
|
Biochem J
|
2009
|
0.86
|
|
15
|
The zinc-binding site of a class I aminoacyl-tRNA synthetase is a SWIM domain that modulates amino acid binding via the tRNA acceptor arm.
|
Eur J Biochem
|
2004
|
0.85
|
|
16
|
Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer.
|
Mol Cell Endocrinol
|
2008
|
0.84
|
|
17
|
A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity.
|
FASEB J
|
2002
|
0.83
|
|
18
|
How estrogen-specific proteins discriminate estrogens from androgens: a common steroid binding site architecture.
|
FASEB J
|
2003
|
0.82
|
|
19
|
The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells.
|
PLoS One
|
2012
|
0.82
|
|
20
|
Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2.
|
J Biol Chem
|
2002
|
0.82
|
|
21
|
Mapping of steroids binding to 17 beta-hydroxysteroid dehydrogenase type 1 using Monte Carlo energy minimization reveals alternative binding modes.
|
Biochemistry
|
2005
|
0.80
|
|
22
|
Crystal structures of human muscle fructose-1,6-bisphosphatase: novel quaternary states, enhanced AMP affinity, and allosteric signal transmission pathway.
|
PLoS One
|
2013
|
0.79
|
|
23
|
Monoclonal antibodies assisting refolding of firefly luciferase.
|
Protein Sci
|
2004
|
0.79
|
|
24
|
Interaction of Androst-5-ene-3β,17β-diol and 5α-androstane-3β,17β-diol with estrogen and androgen receptors: a combined binding and cell study.
|
J Steroid Biochem Mol Biol
|
2013
|
0.79
|
|
25
|
Structure analysis of a new psychrophilic marine protease.
|
PLoS One
|
2011
|
0.79
|
|
26
|
Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity.
|
Antivir Ther
|
2010
|
0.79
|
|
27
|
Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins.
|
Proteins
|
2009
|
0.78
|
|
28
|
Estrone and estradiol C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase.
|
Mol Cell Endocrinol
|
2005
|
0.78
|
|
29
|
Estradiol-adenosine hybrid compounds designed to inhibit type 1 17beta-hydroxysteroid dehydrogenase.
|
J Med Chem
|
2005
|
0.78
|
|
30
|
Human SARS-coronavirus RNA-dependent RNA polymerase: activity determinants and nucleoside analogue inhibitors.
|
Proteins
|
2004
|
0.77
|
|
31
|
Dendritic cell immunoreceptor is a new target for anti-AIDS drug development: identification of DCIR/HIV-1 inhibitors.
|
PLoS One
|
2013
|
0.76
|
|
32
|
Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424.
|
Proteins
|
2004
|
0.75
|
|
33
|
Structure function analysis of west nile virus RNA dependent RNA polymerase: molecular model and implications for drug design.
|
Med Chem
|
2007
|
0.75
|
|
34
|
Analysis and statistics of crystallisation success increase by composition modification of protein and precipitant mixing ratio.
|
Protein Pept Lett
|
2011
|
0.75
|
|
35
|
Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5.
|
Acta Crystallogr D Biol Crystallogr
|
2002
|
0.75
|