PubRank

J Carl Barrett

Author PubWeight™ 213.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 GoMiner: a resource for biological interpretation of genomic and proteomic data. Genome Biol 2003 22.63
2 Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004 14.97
3 Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 2006 8.48
4 Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005 6.79
5 SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 2008 6.02
6 Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat Cell Biol 2004 4.87
7 HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J 2004 4.26
8 A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer. Cancer Res 2008 4.05
9 Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics 2004 3.65
10 Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 2001 3.22
11 Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer. Clin Cancer Res 2005 2.72
12 BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation. Curr Biol 2004 2.67
13 Gene expression analysis reveals chemical-specific profiles. Toxicol Sci 2002 2.50
14 Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary. Cancer Res 2005 2.48
15 Scientific collaboration results in higher citation rates of published articles. Pharmacotherapy 2006 2.39
16 Three microarray platforms: an analysis of their concordance in profiling gene expression. BMC Genomics 2005 2.29
17 Clinical proteomics: translating benchside promise into bedside reality. Nat Rev Drug Discov 2002 2.15
18 PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer. Clin Cancer Res 2010 2.13
19 A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell 2009 2.13
20 Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. Cancer Res 2005 2.08
21 Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme. Cancer Cell 2004 2.05
22 Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis. Carcinogenesis 2004 1.91
23 The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. Hum Mol Genet 2005 1.88
24 Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection. Cancer Res 2006 1.87
25 Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers. Clin Cancer Res 2005 1.86
26 Prediction of compound signature using high density gene expression profiling. Toxicol Sci 2002 1.82
27 Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis 2003 1.82
28 Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors. J Cell Biochem 2004 1.76
29 Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. Cancer Res 2005 1.74
30 Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells. Cancer Res 2004 1.74
31 Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways. Oncogene 2004 1.63
32 Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion. PLoS Biol 2004 1.54
33 Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer. Cancer Res 2003 1.54
34 Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers. Ann N Y Acad Sci 2003 1.50
35 Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones. Nutr Cancer 2008 1.49
36 Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology 2006 1.44
37 Testing guidelines for hereditary non-polyposis colorectal cancer. Nat Rev Cancer 2004 1.43
38 Novel human monoclonal antibodies to insulin-like growth factor (IGF)-II that potently inhibit the IGF receptor type I signal transduction function. Mol Cancer Ther 2006 1.43
39 Rationale for biomarkers and surrogate end points in mechanism-driven oncology drug development. Clin Cancer Res 2004 1.40
40 Use of CA-125 in clinical trial evaluation of new therapeutic drugs for ovarian cancer. Clin Cancer Res 2004 1.36
41 Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression. Mol Biol Cell 2002 1.36
42 Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells. Blood 2004 1.32
43 Closing the gaps on human chromosome 19 revealed genes with a high density of repetitive tandemly arrayed elements. Genome Res 2004 1.30
44 Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus. Mol Carcinog 2003 1.30
45 Properties of switch-like bioregulatory networks studied by simulation of the hypoxia response control system. Mol Biol Cell 2004 1.27
46 Rapid generation of long synthetic tandem repeats and its application for analysis in human artificial chromosome formation. Nucleic Acids Res 2005 1.26
47 Energy balance and carcinogenesis: underlying pathways and targets for intervention. Curr Cancer Drug Targets 2007 1.26
48 Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma. Cancer Res 2006 1.26
49 PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression. Nature 2003 1.24
50 Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics. Lab Invest 2002 1.22
51 The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions. Oncogene 2002 1.22
52 Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models. Clin Cancer Res 2007 1.22
53 Differential cis-regulation of human versus mouse TERT gene expression in vivo: identification of a human-specific repressive element. Proc Natl Acad Sci U S A 2005 1.21
54 Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A 2011 1.21
55 Cell proliferation and apoptosis in human uterine leiomyomas and myometria. Virchows Arch 2002 1.20
56 Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance. Proc Natl Acad Sci U S A 2005 1.19
57 Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer. Clin Cancer Res 2005 1.18
58 Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition. Hum Mol Genet 2004 1.17
59 Extreme obesity reduces bone mineral density: complementary evidence from mice and women. Obesity (Silver Spring) 2007 1.16
60 G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell. Cancer Immunol Immunother 2005 1.14
61 CD82 metastasis suppressor gene: a potential target for new therapeutics? Trends Mol Med 2005 1.11
62 Upregulation of the KIAA1199 gene is associated with cellular mortality. Cancer Lett 2005 1.10
63 Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression. Clin Cancer Res 2007 1.10
64 The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids. Proc Natl Acad Sci U S A 2004 1.09
65 Loss of expression and altered localization of KAI1 and CD9 protein are associated with epithelial ovarian cancer progression. Gynecol Oncol 2002 1.06
66 Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast. EMBO Rep 2003 1.06
67 Accelerated tumor formation in a fatless mouse with type 2 diabetes and inflammation. Cancer Res 2006 1.06
68 Epigenetic mechanisms in human disease. Cancer Res 2002 1.05
69 Diet-gene interactions in p53-deficient mice: insulin-like growth factor-1 as a mechanistic target. J Nutr 2004 1.05
70 Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27. Genome Res 2005 1.04
71 Race/ethnic variation in serum levels of IGF-I and IGFBP-3 in US adults. Growth Horm IGF Res 2008 1.01
72 A genetic system for direct selection of gene-positive clones during recombinational cloning in yeast. Nucleic Acids Res 2002 1.01
73 The fibroid growth study: determinants of therapeutic intervention. J Womens Health (Larchmt) 2009 0.99
74 Phenotypic effects of calorie restriction and insulin-like growth factor-1 treatment on body composition and bone mineral density of C57BL/6 mice: implications for cancer prevention. In Vivo 2005 0.99
75 Effect of exogenous epidermal-like growth factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse. Breast Cancer Res Treat 2003 0.98
76 Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter. J Biol Chem 2002 0.98
77 Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible factor-1? Mol Cancer Res 2003 0.98
78 Serum levels of insulin-like growth factor-I and insulin-like growth factor-I binding protein-3: quality control for studies of stored serum. Cancer Epidemiol Biomarkers Prev 2007 0.97
79 A general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeast. BMC Genomics 2003 0.97
80 Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis. Genes Chromosomes Cancer 2005 0.97
81 Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response. Cancer Res 2009 0.96
82 Microarray analysis and identification of novel molecules involved in insulin-like growth factor-1 receptor signaling and gene expression. Recent Prog Horm Res 2003 0.96
83 Prediction of lymph node metastasis in patients with endometrioid endometrial cancer using expression microarray. Clin Cancer Res 2006 0.96
84 Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters. Int J Cancer 2002 0.95
85 Effects of energy balance on cancer in genetically altered mice. J Nutr 2004 0.92
86 Identification of a </= 600-kb region on human chromosome 1q42.3 inducing cellular senescence. Oncogene 2003 0.91
87 Gene expression profiling of microsatellite unstable and microsatellite stable endometrial cancers indicates distinct pathways of aberrant signaling. Cancer Res 2005 0.91
88 Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1. Cancer Med 2012 0.91
89 Distinct effects of calorie restriction and exercise on mammary gland gene expression in C57BL/6 mice. Cancer Prev Res (Phila) 2009 0.90
90 Reanalysis of cancer drugs: old drugs, new tricks. Clin Cancer Res 2004 0.89
91 Laser capture microdissection, microarrays and the precise definition of a cancer cell. Expert Rev Mol Diagn 2004 0.88
92 Functional evidence for a metastasis suppressor gene for rat prostate cancer within a 60-kilobase region on human chromosome 8p21-p12. Cancer Res 2002 0.88
93 Association of p16(INK4a) and pRb inactivation with immortalization of human cells. Carcinogenesis 2002 0.88
94 Characterization of an antibody that can detect the Kai1/CD82 murine metastasis suppressor. Prostate 2006 0.87
95 Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: identification of novel targets. Mol Carcinog 2004 0.87
96 Assessment of genotoxicity of 14 chemical agents used in dental practice: ability to induce chromosome aberrations in Syrian hamster embryo cells. Mutat Res 2006 0.87
97 Effects of alcohol and menstrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3. Cancer Epidemiol Biomarkers Prev 2004 0.86
98 Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system. Oncogene 2002 0.85
99 Immortalization of normal human embryonic fibroblasts by introduction of either the human papillomavirus type 16 E6 or E7 gene alone. Int J Cancer 2003 0.85
100 DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma. Gynecol Oncol 2003 0.85
101 Ability of fourteen chemical agents used in dental practice to induce chromosome aberrations in Syrian hamster embryo cells. J Pharmacol Sci 2005 0.84
102 Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. Cancer Res 2005 0.84
103 Effects of alcohol on insulin-like growth factor I and insulin-like growth factor binding protein 3 in postmenopausal women. Am J Clin Nutr 2005 0.84
104 The utility of genetically altered mouse models for nutrition and cancer chemoprevention research. Mutat Res 2005 0.84
105 Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid. Free Radic Biol Med 2011 0.84
106 cDNA cloning of the human polybromo-1 gene on chromosome 3p21. DNA Seq 2002 0.84
107 Promoter hypermethylation as an epigenetic component in Type I and Type II endometrial cancers. Ann N Y Acad Sci 2003 0.83
108 BRCA1-mediated repression of select X chromosome genes. J Transl Med 2004 0.81
109 Human chromosome 5 carries a putative telomerase repressor gene. Genes Chromosomes Cancer 2003 0.81
110 Tumor spectrum in the p53 heterozygous zeta globin-promoted Tg.AC (v-Ha-ras) bitransgenic mouse model. Toxicol Pathol 2004 0.80
111 Suppression of metastasis of rat prostate cancer by introduction of human chromosome 13. Asian J Androl 2002 0.80
112 Timing of supplementation with the antioxidant N-acetyl-L-cysteine reduces tumor multiplicity in novel, cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) transgenic mice but has no impact on malignant progression. Nutr Cancer 2002 0.80
113 Cell-transforming activity and mutagenicity of 5 phytoestrogens in cultured mammalian cells. Int J Cancer 2003 0.80
114 Effects of the antiestrogen tamoxifen and the aromatase inhibitor letrozole on serum hormones and bone characteristics in a preclinical tumor model for breast cancer. Clin Cancer Res 2004 0.79
115 A trivalent dimethylarsenic compound, dimethylarsine iodide, induces cellular transformation, aneuploidy, centrosome abnormality and multipolar spindle formation in Syrian hamster embryo cells. Toxicology 2004 0.79
116 Immortal, telomerase-negative cell lines derived from a Li-Fraumeni syndrome patient exhibit telomere length variability and chromosomal and minisatellite instabilities. Carcinogenesis 2003 0.79
117 Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis. Cytotechnology 2004 0.78
118 Mechanisms of metastasis suppression by introduction of human chromosome 10 into rat prostate cancer. Asian J Androl 2002 0.78
119 Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC). Toxicol Sci 2004 0.78
120 Normal viability of Kai1/Cd82 deficient mice. Mol Carcinog 2013 0.78
121 Defining regulatory elements in the human KAI1 (CD 82) metastasis suppressor gene. Prostate 2003 0.78
122 Urothelial overexpression of insulin-like growth factor-1 increases susceptibility to p-cresidine-induced bladder carcinogenesis in transgenic mice. Mol Carcinog 2009 0.78
123 Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers. Int J Cancer 2005 0.77
124 Effects of a catechol-O-methyltransferase inhibitor on catechol estrogen-induced cellular transformation, chromosome aberrations and apoptosis in Syrian hamster embryo cells. Int J Cancer 2007 0.77
125 Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens. Int J Oncol 2008 0.77
126 Multiple human chromosomes carrying tumor-suppressor functions for the mouse melanoma cell line B16-F10, identified by microcell-mediated chromosome transfer. Mol Carcinog 2002 0.76
127 NIH deltanoids meeting on Vitamin D and cancer. Conclusion and strategic options. J Steroid Biochem Mol Biol 2005 0.75
128 Candidate chromosomal regions for genes involved in activation of alternative lengthening of telomeres in human immortal cell lines. Exp Gerontol 2003 0.75
129 The Environmental Genome Project and bioethics. Kennedy Inst Ethics J 1999 0.75