Published in Cancer Sci on February 01, 2003
Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy. J Exp Med (2007) 1.73
The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands. Gut (2014) 1.53
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The time to eradicate gastric cancer is now. Gut (2005) 1.22
Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol (2003) 1.20
Mucin phenotype and narrow-band imaging with magnifying endoscopy for differentiated-type mucosal gastric cancer. J Gastroenterol (2011) 1.03
Histological risk markers for non-cardia early gastric cancer. Pattern of mucin expression and gastric cancer. Virchows Arch (2006) 1.03
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DNA methylation: a marker for carcinogen exposure and cancer risk. Environ Health Prev Med (2007) 0.89
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Intestinal stem cell marker LGR5 expression during gastric carcinogenesis. World J Gastroenterol (2013) 0.88
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Hyperplastic polyps and sessile serrated 'adenomas' of the colon and rectum display gastric pyloric differentiation. Histochem Cell Biol (2007) 0.86
Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells. Scand J Gastroenterol (2008) 0.86
Gastric and intestinal phenotypic cell marker expressions in gastric differentiated-type carcinomas: association with E-cadherin expression and chromosomal changes. J Cancer Res Clin Oncol (2006) 0.84
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Helicobacter pylori infection and gastric carcinogenesis in rodent models. Semin Immunopathol (2012) 0.84
Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells. J Cancer Res Clin Oncol (2003) 0.83
Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins. Am J Pathol (2006) 0.83
Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer. Oncotarget (2015) 0.82
Intestinal Stem Cell Markers in the Intestinal Metaplasia of Stomach and Barrett's Esophagus. PLoS One (2015) 0.82
Altered expression of CDX-2, PDX-1 and mucin core proteins in "Ulcer-associated cell lineage (UACL)" in Crohn's disease. J Mol Histol (2007) 0.81
Microsatellite instability is linked to loss of hMLH1 expression in advanced gastric cancers: lack of a relationship with the histological type and phenotype. Gastric Cancer (2005) 0.81
Genetic Mechanisms and Aberrant Gene Expression during the Development of Gastric Intestinal Metaplasia and Adenocarcinoma. Curr Genomics (2007) 0.80
Establishment and characterization of novel gastric signet-ring cell and non signet-ring cell poorly differentiated adenocarcinoma cell lines with low and high malignant potential. Gastric Cancer (2012) 0.80
Clinicopathological significance of MMP-7, laminin γ2 and EGFR expression at the invasive front of gastric carcinoma. Gastric Cancer (2013) 0.80
Risk factors of gastric cancer specific for tumor location and histology in Cali, Colombia. World J Gastroenterol (2006) 0.80
The relationship among PDX1, CDX2, and mucin profiles in gastric carcinomas; correlations with clinicopathologic parameters. J Cancer Res Clin Oncol (2011) 0.79
Healing, antioxidant and cytoprotective properties of Indigofera truxillensis in different models of gastric ulcer in rats. Int J Mol Sci (2012) 0.78
Clinicopathologic significance of gastric and intestinal phenotypic marker expression in gastric carcinomas. Korean J Intern Med (2005) 0.77
Gastric composite tumor of alpha fetoprotein-producing carcinoma/hepatoid adenocarcinoma and endocrine carcinoma with reference to cellular phenotypes. Patholog Res Int (2012) 0.77
Expression of small intestinal and colonic phenotypes in complete intestinal metaplasia of the human stomach. Virchows Arch (2005) 0.76
Clinicopathological characteristics of human epidermal growth factor receptor 2-positive Barrett's adenocarcinoma. World J Gastroenterol (2012) 0.76
Apoptotic cell death and its relationship to gastric carcinogenesis. World J Gastroenterol (2007) 0.76
Changing the natural history of metachronous gastric cancer after H. pylori eradication. Jpn J Helicobacter Res (2015) 0.75
Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer. Oncotarget (2016) 0.75
Serrated Adenoma of Gastric Antrum: Alteration of Mucin Expression Profile and its Role in Carcinogenesis. Gastroenterology Res (2009) 0.75
Fatty acids in a high-fat diet potentially induce gastric parietal-cell damage and metaplasia in mice. J Gastroenterol (2016) 0.75
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res (2006) 2.69
Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res (2010) 1.80
Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology (2006) 1.47
Long-term high-dose proton pump inhibitor administration to Helicobacter pylori-infected Mongolian gerbils enhances neuroendocrine tumor development in the glandular stomach. Asian Pac J Cancer Prev (2011) 1.39
Gastric acid reduction leads to an alteration in lower intestinal microflora. Biochem Biophys Res Commun (2009) 1.37
Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers. Cancer Res (2004) 1.35
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol Cell Biol (2006) 1.34
Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol (2003) 1.20
High salt diets dose-dependently promote gastric chemical carcinogenesis in Helicobacter pylori-infected Mongolian gerbils associated with a shift in mucin production from glandular to surface mucous cells. Int J Cancer (2006) 1.18
Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia. J Cancer Res Clin Oncol (2003) 1.16
Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation. Cancer Sci (2004) 1.14
Effect of early eradication on Helicobacter pylori-related gastric carcinogenesis in Mongolian gerbils. Cancer Sci (2003) 1.09
Helicobacter pylori infection-negative gastric cancer in Japanese hospital patients: incidence and pathological characteristics. Cancer Sci (2007) 1.07
Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation. Carcinogenesis (2010) 1.05
Synergistic promoting effects of Helicobacter pylori infection and high-salt diet on gastric carcinogenesis in Mongolian gerbils. Jpn J Cancer Res (2002) 1.02
4-Vinyl-2,6-dimethoxyphenol (canolol) suppresses oxidative stress and gastric carcinogenesis in Helicobacter pylori-infected carcinogen-treated Mongolian gerbils. Int J Cancer (2008) 0.94
Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on Helicobacter pylori-induced gastritis in Mongolian gerbils. Int J Cancer (2009) 0.93
Prevention of Helicobacter pylori-induced gastric cancers in gerbils by a DNA demethylating agent. Cancer Prev Res (Phila) (2013) 0.91
Characterization of a monoclonal antibody, HTA28, recognizing a histone H3 phosphorylation site as a useful marker of M-phase cells. J Histochem Cytochem (2004) 0.90
A lipophilic statin, pitavastatin, suppresses inflammation-associated mouse colon carcinogenesis. Int J Cancer (2007) 0.88
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine. Jpn J Cancer Res (2002) 0.87
Expression of osteopontin and CDX2: indications of phenotypes and prognosis in advanced gastric cancer. Oncol Rep (2009) 0.87
Cdx2 expression in pancreatic tumors: Relationship with prognosis of invasive ductal carcinomas. Oncol Rep (2004) 0.86
Global expression analysis of N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas using oligonucleotide microarrays. Carcinogenesis (2003) 0.86
Effects of eradication of Helicobacter pylori on gastric carcinogenesis in experimental models. J Gastroenterol (2007) 0.85
Mixed gastric- and intestinal-type metaplasia is formed by cells with dual intestinal and gastric differentiation. J Histochem Cytochem (2005) 0.85
Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus). J Toxicol Pathol (2011) 0.84
Pathobiology and chemoprevention of bladder cancer. J Oncol (2011) 0.84
Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins. Am J Pathol (2006) 0.83
Eradication of Helicobacter pylori induces apoptosis and inhibits proliferation of heterotopic proliferative glands in infected Mongolian gerbils. Cancer Sci (2004) 0.83
Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells. J Cancer Res Clin Oncol (2003) 0.83
Elevated susceptibility of the p53 knockout mouse esophagus to methyl-N-amylnitrosamine carcinogenesis. Carcinogenesis (2002) 0.83
Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice. Brain Res (2009) 0.83
Role of Helicobacter pylori in gastric carcinogenesis: the origin of gastric cancers and heterotopic proliferative glands in Mongolian gerbils. Helicobacter (2005) 0.83
Beta-catenin gene alteration in glandular stomach adenocarcinomas in N-methyl-N-nitrosourea-treated and Helicobacter pylori-infected Mongolian gerbils. Cancer Sci (2004) 0.83
Severity of gastritis determines glandular stomach carcinogenesis in Helicobacter pylori-infected Mongolian gerbils. Cancer Sci (2007) 0.82
Helicobacter pylori infection and gastric carcinogenesis in animal models. Gastric Cancer (2003) 0.82
Roles of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression and beta-catenin activation in gastric carcinogenesis in N-methyl-N-nitrosourea-treated K19-C2mE transgenic mice. Cancer Sci (2008) 0.82
Anticancer effects of 4-vinyl-2,6-dimethoxyphenol (canolol) against SGC-7901 human gastric carcinoma cells. Oncol Lett (2013) 0.82
Earlier Helicobacter pylori infection increases the risk for the N-methyl-N-nitrosourea-induced stomach carcinogenesis in Mongolian gerbils. Jpn J Cancer Res (2002) 0.81
Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non-cancerous gastric mucosae. Cancer Sci (2007) 0.81
Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea. Cancer Lett (2002) 0.81
Gene expression analysis of a Helicobacter pylori-infected and high-salt diet-treated mouse gastric tumor model: identification of CD177 as a novel prognostic factor in patients with gastric cancer. BMC Gastroenterol (2013) 0.81
Preventive effects of etodolac, a selective cyclooxygenase-2 inhibitor, on cancer development in extensive metaplastic gastritis, a Helicobacter pylori-negative precancerous lesion. Int J Cancer (2010) 0.81
Cerebroprotective effects of TAK-937, a cannabinoid receptor agonist, on ischemic brain damage in middle cerebral artery occluded rats and non-human primates. Brain Res (2011) 0.81
Microsatellite instability is linked to loss of hMLH1 expression in advanced gastric cancers: lack of a relationship with the histological type and phenotype. Gastric Cancer (2005) 0.81
Frequent c-Kit gene mutations not only in gastrointestinal stromal tumors but also in interstitial cells of Cajal in surrounding normal mucosa. Cancer Lett (2005) 0.81
Pitavastatin fails to lower serum lipid levels or inhibit gastric carcinogenesis in helicobacter pylori-infected rodent models. Cancer Prev Res (Phila) (2009) 0.81
Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging. PLoS One (2011) 0.80
Loss of p21WAF1/CIP1 expression in invasive fronts of oral tongue squamous cell carcinomas is correlated with tumor progression and poor prognosis. Oncol Rep (2005) 0.80
Appearance of osteonectin-expressing fibroblastic cells in early rat stomach carcinogenesis and stomach tumors induced with N-methyl-N'-nitro-N-nitrosoguanidine. Jpn J Cancer Res (2002) 0.80
Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils. Cancer Sci (2007) 0.80
Contribution of hypothermia and CB1 receptor activation to protective effects of TAK-937, a cannabinoid receptor agonist, in rat transient MCAO model. PLoS One (2012) 0.79
Reversibility of heterotopic proliferative glands in glandular stomach of Helicobacter pylori-infected Mongolian gerbils on eradication. Jpn J Cancer Res (2002) 0.79
[Effect of high salt diet and Helicobacter pylori infection on gastric carcinogenesis]. Nihon Rinsho (2003) 0.79
Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity. Cancer Lett (2002) 0.79
Protection from inflammatory bowel disease and colitis-associated carcinogenesis with 4-vinyl-2,6-dimethoxyphenol (canolol) involves suppression of oxidative stress and inflammatory cytokines. Carcinogenesis (2013) 0.79
Lack of initiation activity of 4-oxo-2-hexenal, a peroxidation product generated from omega-3 polyunsaturated fatty acids, in an in vivo five-week liver assay. Asian Pac J Cancer Prev (2007) 0.78
Whole-genome analyses of loss of heterozygosity and methylation analysis of four tumor-suppressor genes in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas. Cancer Sci (2005) 0.78
Coexistence of gastric- and intestinal-type endocrine cells in gastric and intestinal mixed intestinal metaplasia of the human stomach. Pathol Int (2005) 0.78
Organ-specific susceptibility of p53 knockout mice to N-bis(2-hydroxypropyl)nitrosamine carcinogenesis. Cancer Lett (2005) 0.78
Identification of a DNA methylation marker that detects the presence of lymph node metastases of gastric cancers. Oncol Lett (2012) 0.77
Suppressive effects of fruit-juice concentrate of Prunus mume Sieb. et Zucc. (Japanese apricot, Ume) on Helicobacter pylori-induced glandular stomach lesions in Mongolian gerbils. Asian Pac J Cancer Prev (2005) 0.77
Helicobacter pylori infection stimulates intestinalization of endocrine cells in glandular stomach of Mongolian gerbils. Cancer Sci (2006) 0.77
Inhibitory effect of etodolac, a selective cyclooxygenase-2 inhibitor, on stomach carcinogenesis in Helicobacter pylori-infected Mongolian gerbils. Biochem Biophys Res Commun (2005) 0.77
High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine. J Cancer Res Clin Oncol (2003) 0.77
Lansoprazole induces collagenous colitis in the colon of Mongolian gerbils. Asian Pac J Cancer Prev (2011) 0.77
Gastric phenotypic expression and histogenesis of metachronous gastric cancers endoscopically resected. Hepatogastroenterology (2009) 0.76
Development of carcinoid tumors of the glandular stomach and effects of eradication in Helicobacter pylori-infected Mongolian gerbils. Asian Pac J Cancer Prev (2008) 0.76
Gastric and intestinal phenotypes and histogenesis of advanced glandular stomach cancers in carcinogen-treated, Helicobacter pylori-infected Mongolian gerbils. Cancer Sci (2006) 0.76
Effects of aspirin on the development of Helicobacter pylori-induced gastric inflammation and heterotopic proliferative glands in Mongolian gerbils. Helicobacter (2008) 0.76
Pharmacological characterization of M-II, the major human metabolite of ramelteon. Pharmacology (2014) 0.76
Expression of small intestinal and colonic phenotypes in complete intestinal metaplasia of the human stomach. Virchows Arch (2005) 0.76
Antigenotoxic effects of p53 on spontaneous and ultraviolet light B--induced deletions in the epidermis of gpt delta transgenic mice. Environ Mol Mutagen (2010) 0.76
Ovarian mucinous tumor arising in mature cystic teratoma associated with pseudomyxoma peritonei: a case with possible respiratory epithelial differentiation. Int J Gynecol Pathol (2008) 0.75
[Helicobacter pylori infection and gastric carcinogenesis]. Nihon Shokakibyo Gakkai Zasshi (2002) 0.75
Carcinogenic risk of heterocyclic amines in combination - assessment with a liver initiation model. Food Chem Toxicol (2008) 0.75
Gigantic lymphangioma with marked extraluminal progression of the ascending colon: report of a case. Surg Today (2014) 0.75
Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Cancer Lett (2003) 0.75
Organ-dependent susceptibility of p53 knockout mice to 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). Cancer Sci (2007) 0.75
Cyclin D1 overexpression in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric adenocarcinomas. Exp Toxicol Pathol (2007) 0.75
Endoscopic mucosal resection of a rectal malakoplakia in a healthy adult. Dig Endosc (2013) 0.75
Lack of elevated liver carcinogenicity of aminophenylnorharman in p53-deficient mice. Cancer Lett (2005) 0.75
Induction of glandular stomach cancers in Helicobacter pylori-infected Mongolian gerbils by 1-nitrosoindole-3-acetonitrile. Int J Cancer (2011) 0.75
Colonic and small-intestinal phenotypes in gastric cancers: relationships with clinicopathological findings. Pathol Int (2005) 0.75
Gastric-and-intestinal mixed endocrine cell phenotypic expression of carcinoid tumors in the rectum. Oncol Rep (2009) 0.75
Early development of histiocytic sarcomas in p53 knockout mice treated with N-bis(2-hydroxypropyl)nitrosamine. Oncol Rep (2007) 0.75
[Gastric cancer and eradication of H. pylori]. Gan To Kagaku Ryoho (2007) 0.75
Intestinal phenotypes of stomach cancers arising after Helicobacter pylori eradication in carcinogen-treated Mongolian gerbils. Asian Pac J Cancer Prev (2007) 0.75
Endoscopic observation of N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rat using a newly-developed flexible endoscope. Asian Pac J Cancer Prev (2009) 0.75
Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (TAK-802) and related compounds. Bioorg Med Chem (2005) 0.75
Summation of initiation activities in the liver after partial hepatectomy. Cancer Lett (2002) 0.75
Intraperitoneal injection of D-galactosamine provides a potent cell proliferation stimulus for the detection of initiation activities of chemicals in rat liver. J Appl Toxicol (2005) 0.75
Lack of potential of low dose N-nitrosodimethylamine to induce preneoplastic lesions, glutathione S-transferase placental form-positive foci, in rat liver. Cancer Lett (2005) 0.75