Published in J Mol Med (Berl) on April 30, 2003
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Sci Transl Med (2013) 1.55
Tnni3k modifies disease progression in murine models of cardiomyopathy. PLoS Genet (2009) 1.44
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nat Genet (2017) 1.44
Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene. Endocr Rev (2013) 1.40
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet (2013) 1.23
QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. Mamm Genome (2005) 1.03
Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction. PLoS Genet (2012) 0.93
TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. Hum Mol Genet (2014) 0.89
TNNI3K, a cardiac-specific kinase, promotes physiological cardiac hypertrophy in transgenic mice. PLoS One (2013) 0.86
Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. J Mol Cell Cardiol (2012) 0.84
Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene. J Cell Mol Med (2007) 0.80
Identification of a cardiac disease modifier gene using forward genetics in the mouse. PLoS Genet (2009) 0.78
Hearts of this ILK rely on TNNI3K, a MAPKKK that regulated TNNI3. J Mol Med (Berl) (2003) 0.77
TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I. Braz J Med Biol Res (2013) 0.76
Troponin I-interacting protein kinase: a novel cardiac-specific kinase, emerging as a molecular target for the treatment of cardiac disease. Circ J (2014) 0.75
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc Natl Acad Sci U S A (2005) 2.29
The peripheral-blood transcriptome: new insights into disease and risk assessment. Trends Mol Med (2007) 1.91
Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene (2004) 1.77
A blood-based biomarker panel for stratifying current risk for colorectal cancer. Int J Cancer (2010) 1.70
Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. Physiol Genomics (2002) 1.57
Adriamycin-induced cardiomyocyte and endothelial cell apoptosis: in vitro and in vivo studies. J Mol Cell Cardiol (2002) 1.53
Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. Circ Res (2006) 1.46
Novel blood biomarkers of human urinary bladder cancer. Clin Cancer Res (2006) 1.44
Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray. Am J Pathol (2002) 1.38
Gene expression profile of zebrafish exposed to hypoxia during development. Physiol Genomics (2003) 1.35
Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. Am J Pathol (2005) 1.32
Gene profiling identifies secreted protein transcripts from peripheral blood cells in coronary artery disease. J Mol Cell Cardiol (2003) 1.09
Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury. Am J Physiol Heart Circ Physiol (2008) 1.05
Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development. Biochem Biophys Res Commun (2002) 1.01
Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. Atherosclerosis (2006) 0.97
Blood-based biomarkers can differentiate ulcerative colitis from Crohn's disease and noninflammatory diarrhea. Inflamm Bowel Dis (2011) 0.96
Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro. Hypertension (2010) 0.94
A case-controlled validation study of a blood-based seven-gene biomarker panel for colorectal cancer in Malaysia. J Exp Clin Cancer Res (2010) 0.92
Blood gene expression signatures associate with heart failure outcomes. Physiol Genomics (2011) 0.91
Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol (2004) 0.90
Similarities and differences in peripheral blood gene-expression signatures of individuals with schizophrenia and their first-degree biological relatives. Am J Med Genet B Neuropsychiatr Genet (2011) 0.87
Adenovirus-mediated overexpression of cardiac troponin I-interacting kinase promotes cardiomyocyte hypertrophy. Clin Exp Pharmacol Physiol (2011) 0.87
Tissue extracts from infarcted myocardium of rats in promoting the differentiation of bone marrow stromal cells into cardiomyocyte-like cells. Biomed Environ Sci (2008) 0.87
Molecular Cloning of NELIN, a Putative Human Cytoskeleton Regulation Gene. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2001) 0.86
Chromosomal distribution of the human cardiovascular transcriptome. Genomics (2003) 0.85
Whole blood transcriptome correlates with treatment response in nasopharyngeal carcinoma. J Exp Clin Cancer Res (2012) 0.85
AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity. Biochemistry (Mosc) (2007) 0.84
Differential regulation of peripheral leukocyte genes in patients with active Crohn's disease and Crohn's disease in remission. J Clin Gastroenterol (2010) 0.84
Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry. J Pharm Biomed Anal (2012) 0.83
[Plasmid transfection of rat bone marrow mesenchymal stem cells by cationic lipid for gene-modified cell transplantation therapy]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2005) 0.80
Multiple target cell extraction and LC-MS analysis for predicting bioactive components in Radix Salviae miltiorrhizae. Biol Pharm Bull (2008) 0.80
Determination of fifteen bioactive components in Radix et Rhizoma Salviae Miltiorrhizae by high-performance liquid chromatography with ultraviolet and mass spectrometric detection. Biomed Chromatogr (2008) 0.80
Blood gene signature for early hepatocellular carcinoma detection in patients with chronic hepatitis B. J Clin Gastroenterol (2015) 0.79
[Gelatin microspheres containing vascular endothelial growth factor enhances the efficacy of bone marrow mesenchymal stem cells transplantation in a swine model of myocardial infarction.]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 0.79
Effect of the CYP2C19 2 and 3 genotypes, ABCB1 C3435T and PON1 Q192R alleles on the pharmacodynamics and adverse clinical events of clopidogrel in Chinese people after percutaneous coronary intervention. Eur J Clin Pharmacol (2012) 0.79
Blood RNA biomarker panel detects both left- and right-sided colorectal neoplasms: a case-control study. J Exp Clin Cancer Res (2013) 0.78
Enhancement of epimedium fried with suet oil based on in vivo formation of self-assembled flavonoid compound nanomicelles. Molecules (2012) 0.78
"Chip"ping away at heart failure. Methods Mol Med (2006) 0.78
Embryonic stem cell transplantation for the treatment of myocardial infarction: immune privilege or rejection. Transpl Immunol (2007) 0.78
[Impact of cytochrome P450 2C19 polymorphisms on outcome of cardiovascular events in clopidogrel-treated Chinese patients after percutaneous coronary intervention]. Zhonghua Xin Xue Guan Bing Za Zhi (2011) 0.77
Blood-based biomarkers used to predict disease activity in Crohn's disease and ulcerative colitis. Inflamm Bowel Dis (2015) 0.77
PKA-mediated eNOS phosphorylation in the protection of ischemic preconditioning against no-reflow. Microvasc Res (2012) 0.77
[Screening on antiosteoporotic active parts of dipsacus radix based on zebrafish model]. Zhong Yao Cai (2014) 0.77
Elevated plasma YKL-40 as a prognostic indicator in patients with idiopathic pulmonary arterial hypertension. Respirology (2014) 0.77
Characterization of the effect of penehyclidine hydrochloride on muscarinic receptor subtypes mediating the contraction of guinea-pig isolated gastrointestinal smooth muscle. J Pharm Pharmacol (2009) 0.76
TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I. Braz J Med Biol Res (2013) 0.76
GeneNews Limited: bringing the blood transcriptome to personalized medicine. Pharmacogenomics (2012) 0.76
[Processing mechanism of Epimedium fried with suet oil based on absorption and metabolism of flavonoids]. Zhongguo Zhong Yao Za Zhi (2014) 0.76
3-[(E)-2-Chloro-3,3,3-trifluoro-prop-1-en-1-yl]-N-(2-fluoro-phen-yl)-2,2-dimethyl-cyclo-propane-1-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
3-[(E)-2-Chloro-3,3,3-trifluoro-prop-1-en-1-yl]-N-(2-chloro-phen-yl)-2,2-dimethyl-cyclo-propane-1-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
(E)-2-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-N-(2,4-dimethyl-phen-yl)-3,3-dimethyl-cyclo-propane-1-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2009) 0.75
(E)-3-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-N-(3-methoxy-phen-yl)-2,2-dimethyl-cyclo-propane-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2007) 0.75
(E)-3-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-2,2-dimethyl-N-p-tolyl-cyclo-propane-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2008) 0.75
(E)-3-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-2,2-dimethyl-N,N-diphenyl-cyclo-propane-carboxamide. Acta Crystallogr Sect E Struct Rep Online (2007) 0.75
Overexpression of Cardiac-Specific Kinase TNNI3K Promotes Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes. Cell Physiol Biochem (2017) 0.75
[Culture medium based on biogas slurry and breeding of oil Chlorella]. Huan Jing Ke Xue (2014) 0.75
Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection. Biomed Chromatogr (2008) 0.75
[Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier]. Zhongguo Zhong Yao Za Zhi (2014) 0.75
[Ideas and methods of two-dimensional zebrafish model combined with chromatographic techniques in high-throughput screening of active anti-osteoporosis components of traditional Chinese medicines]. Zhongguo Zhong Yao Za Zhi (2014) 0.75
[Cloning and characterization of a novel cardiac-specific kinase gene p93 related to sarcomere]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2003) 0.75
[Two-dimensional zebrafish model combined with hyphenated chromatographic techniques for evaluation anti-osteoporosis activity of epimendin A and its metabolite baohuoside I]. Yao Xue Xue Bao (2014) 0.75