Published in Mol Cell Biochem on March 26, 1976
Sugar transport in rat liver lysosomes. Direct demonstration by using labelled sugars. Biochem J (1983) 1.90
Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes. Biochem J (1978) 1.51
Coordinate modulation of D-glucose transport activity and bilayer fluidity in plasma membranes derived from control and insulin-treated adipocytes. Proc Natl Acad Sci U S A (1980) 1.45
Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6. Proc Natl Acad Sci U S A (1987) 1.26
Effect of thyroid status on insulin action in rat adipocytes and skeletal muscle. J Clin Invest (1980) 1.06
Insulin signalling mechanisms for triacylglycerol storage. Diabetologia (2013) 1.00
Effect of cytochalasin B and D on groups of insulin receptors and on insulin action in rat adipocytes. Possible evidence for a structural relationship of the insulin receptor to the glucose transport system. J Clin Invest (1979) 0.96
Cytochalasin B as a probe for the two hexose-transport systems in rat L6 myoblasts. Biochem J (1988) 0.89
In vitro effects of a sulfonylurea on insulin action in adipocytes. Potentiation of insulin-stimulated hexose transport. J Clin Invest (1981) 0.88
Insulin degradation by adipose tissue. Studies at several levels of cellular organization. Biochem J (1980) 0.85
Particulate' hexokinase activity in rat intestine. The comparative contributions of mitochondria and brush-border membranes. Biochem J (1976) 0.85
Temperature optimum of insulin-stimulated 2-deoxy-D-glucose uptake in rat adipocytes. Correlation of cellular transport with membrane spin-label and fluorescence-label data. Biochem J (1984) 0.77
Cadmium-induced stimulation of lipogenesis from glucose in rat adipocytes. Biochem J (1984) 0.75
Insulin binding and insulin action in cultured fibroblasts: significant differences between a phosphoglucose isomerase-deficient mutant and the parental strain. Proc Natl Acad Sci U S A (1986) 0.75
Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains. Science (1997) 3.91
A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains. J Biol Chem (1997) 3.19
Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons. J Biol Chem (1979) 2.83
The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor. J Biol Chem (1982) 2.62
The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes. J Biol Chem (1980) 2.51
Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654. Proc Natl Acad Sci U S A (1985) 2.36
FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains. Cell (1992) 2.28
Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity. J Biol Chem (1984) 2.21
Molecular basis of insulin action. Annu Rev Biochem (1977) 2.16
Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries. Proc Natl Acad Sci U S A (1980) 2.15
Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes. Science (1993) 2.14
Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains. Mol Cell (2000) 2.13
A double leucine within the GLUT4 glucose transporter COOH-terminal domain functions as an endocytosis signal. J Cell Biol (1994) 2.08
Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulin. Proc Natl Acad Sci U S A (1974) 2.06
The nature and regulation of the insulin receptor: structure and function. Annu Rev Physiol (1985) 1.98
Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (1998) 1.83
Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction. Trends Cell Biol (1998) 1.68
A single receptor binds both insulin-like growth factor II and mannose-6-phosphate. Science (1988) 1.68
Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts. J Biol Chem (1988) 1.59
Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain. J Biol Chem (1996) 1.58
Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane. J Biol Chem (1986) 1.56
ADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1. J Biol Chem (1999) 1.53
Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor. J Biol Chem (1984) 1.52
Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis. Cancer Res (1988) 1.51
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells. Mol Cell Biol (1995) 1.48
A unique proteolytic cleavage site on the beta subunit of the insulin receptor. J Biol Chem (1981) 1.46
Distinct polyphosphoinositide binding selectivities for pleckstrin homology domains of GRP1-like proteins based on diglycine versus triglycine motifs. J Biol Chem (2000) 1.45
Coordinate modulation of D-glucose transport activity and bilayer fluidity in plasma membranes derived from control and insulin-treated adipocytes. Proc Natl Acad Sci U S A (1980) 1.45
Affinity labeling of a transforming growth factor receptor that does not interact with epidermal growth factor. Proc Natl Acad Sci U S A (1982) 1.44
Photoaffinity labeling of the human erythrocyte D-glucose transporter. J Biol Chem (1982) 1.43
Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development. Mol Cell Biol (1997) 1.43
Photoaffinity labeling of insulin-sensitive hexose transporters in intact rat adipocytes. Direct evidence that latent transporters become exposed to the extracellular space in response to insulin. J Biol Chem (1984) 1.40
Hexose transport in isolated brown fat cells. A model system for investigating insulin action on membrane transport. J Biol Chem (1974) 1.39
The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase. J Biol Chem (1996) 1.37
Insulin regulation of hexose transport in mouse 3T3-L1 cells expressing the human HepG2 glucose transporter. J Biol Chem (1990) 1.37
Insulin action and the regulation of hexose transport. Diabetes (1980) 1.33
RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27. Acta Physiol (Oxf) (2008) 1.33
Cytochalasin B-sensitive 2-deoxy-D-glucose transport in adipose cell ghosts. J Biol Chem (1973) 1.31
Cellular basis of insulin insensitivity in large rat adipocytes. J Clin Invest (1976) 1.31
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis. J Biol Chem (1985) 1.30
A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes. J Biol Chem (2001) 1.30
Evidence that insulin activates an intrinsic plasma membrane protease in generating a secondary chemical mediator. J Biol Chem (1980) 1.29
Phosphorylation of transcriptional factors and cell-cycle-dependent proteins by casein kinase II. Curr Opin Cell Biol (1991) 1.29
Amiloride directly inhibits growth factor receptor tyrosine kinase activity. J Biol Chem (1985) 1.28
Insulin activates the appearance of insulin-like growth factor II receptors on the adipocyte cell surface. Proc Natl Acad Sci U S A (1984) 1.27
beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes. J Biol Chem (1983) 1.25
Phox homology domains specifically bind phosphatidylinositol phosphates. Biochemistry (2001) 1.24
Hexose transport stimulation and membrane redistribution of glucose transporter isoforms in response to cholera toxin, dibutyryl cyclic AMP, and insulin in 3T3-L1 adipocytes. J Biol Chem (1990) 1.24
Identification of a nerve growth factor receptor protein in sympathetic ganglia membranes by affinity labeling. J Biol Chem (1981) 1.23
Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor. J Biol Chem (1995) 1.22
Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C. Biochemistry (1990) 1.22
The high affinity insulin receptor mediates growth stimulation in rat hepatoma cells. J Biol Chem (1982) 1.21
Role of disulfides in the subunit structure of the insulin receptor. Reduction of class I disulfides does not impair transmembrane signalling. J Biol Chem (1982) 1.20
The ras signaling pathway mimics insulin action on glucose transporter translocation. Proc Natl Acad Sci U S A (1993) 1.20
Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes. J Biol Chem (1998) 1.20
Evidence for electron transfer reactions involved in the Cu2+ -dependent thiol activation of fat cell glucose utilization. J Biol Chem (1974) 1.17
Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate. Proc Natl Acad Sci U S A (2001) 1.16
Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless. J Biol Chem (1995) 1.16
A role for phospholipase D in GLUT4 glucose transporter translocation. J Biol Chem (2000) 1.15
Regulation of transferrin receptor expression at the cell surface by insulin-like growth factors, epidermal growth factor and platelet-derived growth factor. EMBO J (1986) 1.15
Affinity labeling of multiplication stimulating activity receptors in membranes from rat and human tissues. J Biol Chem (1981) 1.14
Insulin regulation of membrane-associated insulin receptor substrate 1. J Biol Chem (1995) 1.13
Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts. J Biol Chem (1987) 1.13
The type II insulin-like growth factor receptor does not mediate increased DNA synthesis in H-35 hepatoma cells. J Biol Chem (1984) 1.13
Insulin-like growth factor I and epidermal growth factor regulate the expression of transferrin receptors at the cell surface by distinct mechanisms. J Biol Chem (1987) 1.13
Activation of cell surface glucose transporters measured by photoaffinity labeling of insulin-sensitive 3T3-L1 adipocytes. J Biol Chem (1992) 1.13
Sensitivity of the adipocyte D-glucose transport system to membrane fluidity in reconstituted vesicles. J Biol Chem (1979) 1.12
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654. Proc Natl Acad Sci U S A (1985) 1.12
Phosphorylation of the Ras nucleotide exchange factor son of sevenless by mitogen-activated protein kinase. J Biol Chem (1994) 1.12
Structural and functional homologies in the receptors for insulin and the insulin-like growth factors. Cell (1982) 1.12
The type I insulin-like growth factor receptor mediates the rapid effects of multiplication-stimulating activity on membrane transport systems in rat soleus muscle. J Biol Chem (1984) 1.10
Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes. J Biol Chem (2000) 1.10
Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain. J Biol Chem (1989) 1.10
Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin. J Biol Chem (1995) 1.09
Primary role of decreased fatty acid synthesis in insulin resistance of large rat adipocytes. Am J Physiol (1978) 1.09
Suppressed intrinsic catalytic activity of GLUT1 glucose transporters in insulin-sensitive 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1991) 1.09
Evidence that functional erythrocyte-type glucose transporters are oligomers. J Biol Chem (1991) 1.08
Purification and reconstitution of the adipocyte plasma membrane D-glucose transport system. J Biol Chem (1977) 1.08
Molecular cloning of the human casein kinase II alpha subunit. Biochemistry (1989) 1.08
src kinase catalyzes the phosphorylation and activation of the insulin receptor kinase. J Biol Chem (1985) 1.07
Effect of thyroid status on insulin action in rat adipocytes and skeletal muscle. J Clin Invest (1980) 1.06
Protein synthesis inhibitors activate glucose transport without increasing plasma membrane glucose transporters in 3T3-L1 adipocytes. J Biol Chem (1991) 1.06
Insulin action rapidly modulates the apparent affinity of the insulin-like growth factor II receptor. J Biol Chem (1983) 1.06
In vivo functional analysis of the Ras exchange factor son of sevenless. Science (1995) 1.06
Tyrosine phosphorylation of insulin receptor beta subunit activates the receptor tyrosine kinase in intact H-35 hepatoma cells. J Biol Chem (1986) 1.05
Hormone binding alters the conformation of the insulin receptor. Science (1980) 1.05
G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane. Mol Cell Biol (2001) 1.04
Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle. Mol Cell Biol (1994) 1.03
Characterization of (3H)cytochalasin B binding to the fat cell plasma membrane. J Biol Chem (1976) 1.03
Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1. J Biol Chem (2001) 1.03
Reconstitution of D-glucose transport activity from cytoplasmic membranes. Evidence against recruitment of cytoplasmic membrane transporters into the plasma membrane as the sole action of insulin. J Biol Chem (1980) 1.02
Insulin response in skeletal muscle and fat cells of the genetically obese Zucker rat. Metabolism (1978) 1.00
Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor. Proc Natl Acad Sci U S A (1992) 1.00
Purification of the adipocyte insulin receptor by immunoaffinity chromatography. J Biol Chem (1980) 1.00
Insulin-sensitive phosphorylation of serine 1293/1294 on the human insulin receptor by a tightly associated serine kinase. J Biol Chem (1990) 0.99
Identification of the stereospecific hexose transporter from starved and fed chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1982) 0.99
Insulin-mediated targeting of phosphatidylinositol 3-kinase to GLUT4-containing vesicles. J Biol Chem (1996) 0.99
The type II insulin-like growth factor receptor is internalized and recycles in the absence of ligand. J Biol Chem (1986) 0.99
Insulin stimulates a membrane-bound serine kinase that may be phosphorylated on tyrosine. Proc Natl Acad Sci U S A (1987) 0.99