Published in Stem Cells on January 01, 2003
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol (2007) 1.71
Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold. Biomaterials (2011) 1.58
Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med (2011) 1.57
Mesenchymal stem cells migration homing and tracking. Stem Cells Int (2013) 1.49
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma. Oncogene (2005) 1.45
Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy. Stem Cells Int (2012) 1.41
Cell based therapies for ischemic stroke: from basic science to bedside. Prog Neurobiol (2013) 1.39
Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status. BMC Cell Biol (2011) 1.38
Hypoxia and stem cell-based engineering of mesenchymal tissues. Biotechnol Prog (2009) 1.36
Bone marrow stem cell derived paracrine factors for regenerative medicine: current perspectives and therapeutic potential. Bone Marrow Res (2010) 1.34
Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors. J Cell Mol Med (2007) 1.33
Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization. Mol Med (2011) 1.31
Mesenchymal stem cells: Molecular characteristics and clinical applications. World J Stem Cells (2010) 1.27
Aging and diabetes impair the neovascular potential of adipose-derived stromal cells. Plast Reconstr Surg (2009) 1.18
Secretome from mesenchymal stem cells induces angiogenesis via Cyr61. J Cell Physiol (2009) 1.16
Improved survival of mesenchymal stromal cell after hypoxia preconditioning: role of oxidative stress. Life Sci (2010) 1.14
Stem cells as vectors for antitumour therapy. Thorax (2010) 1.14
Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation. Am J Physiol Cell Physiol (2011) 1.13
Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. Am J Pathol (2011) 1.12
A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia. J Transl Med (2013) 1.11
Hypoxia preconditioned bone marrow mesenchymal stem cells promote liver regeneration in a rat massive hepatectomy model. Stem Cell Res Ther (2013) 1.05
Enhancing the efficacy of mesenchymal stem cell therapy. World J Stem Cells (2014) 0.99
Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells. Int J Mol Sci (2013) 0.97
High targeted migration of human mesenchymal stem cells grown in hypoxia is associated with enhanced activation of RhoA. Stem Cell Res Ther (2013) 0.97
Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision. Neoplasia (2007) 0.94
Evidence for transcriptional regulation of the glucose-6-phosphate transporter by HIF-1alpha: Targeting G6PT with mumbaistatin analogs in hypoxic mesenchymal stromal cells. Stem Cells (2009) 0.93
The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications. ScientificWorldJournal (2011) 0.91
The role of adipose-derived stem cells in breast cancer progression and metastasis. Stem Cells Int (2015) 0.90
A comparison of the reparative and angiogenic properties of mesenchymal stem cells derived from the bone marrow of BALB/c and C57/BL6 mice in a model of limb ischemia. Stem Cell Res Ther (2013) 0.89
MT1-MMP modulates bFGF-induced VEGF-A expression in corneal fibroblasts. Protein Pept Lett (2012) 0.89
Cellular kinetics of perivascular MSC precursors. Stem Cells Int (2013) 0.88
Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls. Mol Ther (2014) 0.88
Hypoxia pretreatment of bone marrow mesenchymal stem cells facilitates angiogenesis by improving the function of endothelial cells in diabetic rats with lower ischemia. PLoS One (2015) 0.88
In situ tissue regeneration: chemoattractants for endogenous stem cell recruitment. Tissue Eng Part B Rev (2013) 0.87
Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy? World J Stem Cells (2016) 0.86
Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning. Stem Cells Transl Med (2014) 0.85
The Effect of Hypoxia on Mesenchymal Stem Cell Biology. Adv Pharm Bull (2015) 0.85
Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prions. J Virol (2011) 0.85
Nerve growth factor induces cord formation of mesenchymal stem cell by promoting proliferation and activating the PI3K/Akt signaling pathway. Acta Pharmacol Sin (2011) 0.84
Granulocyte-colony-stimulating factor stimulation of bone marrow mesenchymal stromal cells promotes CD34+ cell migration via a matrix metalloproteinase-2-dependent mechanism. Stem Cells Dev (2012) 0.82
The primary cilium as a biomarker in the hypoxic adaptation of bone marrow-derived mesenchymal stromal cells: a role for the secreted frizzled-related proteins. Biomark Insights (2011) 0.82
A concerted HIF-1α/MT1-MMP signalling axis regulates the expression of the 3BP2 adaptor protein in hypoxic mesenchymal stromal cells. PLoS One (2011) 0.82
Hypoxia-mimetic agents inhibit proliferation and alter the morphology of human umbilical cord-derived mesenchymal stem cells. BMC Cell Biol (2011) 0.81
Protective effects of mesenchymal stem cells with CXCR4 up-regulation in a rat renal transplantation model. PLoS One (2013) 0.81
Mesenchymal stromal cells from donors varying widely in age are of equal cellular fitness after in vitro expansion under hypoxic conditions. Cytotherapy (2010) 0.81
Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators. J Cell Physiol (2012) 0.80
Soluble factors from biofilms of wound pathogens modulate human bone marrow-derived stromal cell differentiation, migration, angiogenesis, and cytokine secretion. BMC Microbiol (2015) 0.80
Effect of low oxygen tension on the biological characteristics of human bone marrow mesenchymal stem cells. Cell Stress Chaperones (2016) 0.79
Directed oxygen gradients initiate a robust early remodeling response in engineered vascular grafts. Tissue Eng Part A (2013) 0.78
Effects of matrix metalloproteinases on the fate of mesenchymal stem cells. Stem Cell Res Ther (2016) 0.77
Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature within the Process of Vascular Remodeling: Cellular Basis, Clinical Relevance, and Implications for Stem Cell Therapy. Stem Cells Int (2016) 0.77
Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival. Stem Cells Int (2016) 0.77
Stromal cell-derived factor-1-directed bone marrow mesenchymal stem cell migration in response to inflammatory and/or hypoxic stimuli. Cell Adh Migr (2016) 0.76
Oxygen Tension Regulates Human Mesenchymal Stem Cell Paracrine Functions. Stem Cells Transl Med (2015) 0.76
Hypoxia inducible factor-stabilizing bioactive glasses for directing mesenchymal stem cell behavior. Tissue Eng Part A (2014) 0.76
Corticosterone mediates the inhibitory effect of restraint stress on the migration of mesenchymal stem cell to carbon tetrachloride-induced fibrotic liver by downregulating CXCR4/7 expression. Stem Cells Dev (2014) 0.76
Melanoma educates mesenchymal stromal cells towards vasculogenic mimicry. Oncol Lett (2016) 0.76
Acute Hypoxic Stress Affects Migration Machinery of Tissue O2-Adapted Adipose Stromal Cells. Stem Cells Int (2016) 0.75
Endothelial differentiation of bone marrow mesenchyme stem cells applicable to hypoxia and increased migration through Akt and NFκB signals. Stem Cell Res Ther (2017) 0.75
Adipose Stem Cells Display Higher Regenerative Capacities and More Adaptable Electro-Kinetic Properties Compared to Bone Marrow-Derived Mesenchymal Stromal Cells. Sci Rep (2016) 0.75
Oxygen tension variation in ischemic gastrocnemius muscle, marrow, and different hypoxic conditions in vitro. Med Sci Monit (2014) 0.75
Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta. Stem Cell Res Ther (2016) 0.75
Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ. Respir Res (2016) 0.75
A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression. Gene Regul Syst Bio (2017) 0.75
Cavin-2 Functions as a Suppressive Regulator in TNF-induced Mesenchymal Stromal Cell Inflammation and Angiogenic Phenotypes. Int J Stem Cells (2016) 0.75
[Therapeutic utilization of stem cells in orthopedics]. Orthopade (2017) 0.75
Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease. N Engl J Med (2005) 4.26
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Sci Transl Med (2011) 2.97
Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med (2009) 2.60
Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood (2005) 2.39
Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner. J Immunol (2009) 2.11
Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol (2009) 1.76
Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation. Mol Ther (2011) 1.70
Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood (2009) 1.70
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. Mol Biol Cell (2003) 1.67
Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing. Cytotherapy (2011) 1.65
Interferon-gamma-stimulated marrow stromal cells: a new type of nonhematopoietic antigen-presenting cell. Blood (2005) 1.60
Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene (2002) 1.59
Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform. Cytotherapy (2010) 1.58
Adoptive transfer of mesenchymal stromal cells accelerates intestinal epithelium recovery of irradiated mice in an interleukin-6-dependent manner. Cytotherapy (2012) 1.53
Immunological characterization of multipotent mesenchymal stromal cells--The International Society for Cellular Therapy (ISCT) working proposal. Cytotherapy (2013) 1.52
Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway. Exp Cell Res (2012) 1.51
Coupling erythropoietin secretion to mesenchymal stromal cells enhances their regenerative properties. Cardiovasc Res (2008) 1.51
Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and tumor cell migration. J Biol Chem (2007) 1.50
Inhibition of sphingosine-1-phosphate- and vascular endothelial growth factor-induced endothelial cell chemotaxis by red grape skin polyphenols correlates with a decrease in early platelet-activating factor synthesis. Free Radic Biol Med (2005) 1.43
Propranolol suppresses angiogenesis in vitro: inhibition of proliferation, migration, and differentiation of endothelial cells. Vascul Pharmacol (2010) 1.43
Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes. Biochem J (2002) 1.42
Radiation induced-tubulogenesis in endothelial cells is antagonized by the antiangiogenic properties of green tea polyphenol (-) epigallocatechin-3-gallate. Cancer Biol Ther (2003) 1.42
Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density. J Immunol (2007) 1.41
Therapeutic angiogenesis using autologous bone marrow stromal cells: improved blood flow in a chronic limb ischemia model. Ann Thorac Surg (2003) 1.39
Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. J Biol Chem (2002) 1.37
Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion. Pharmacol Res (2009) 1.36
Modulation of celecoxib pharmacokinetics by food in pediatric patients. Clin Pharmacol Ther (2005) 1.33
A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties. Nat Med (2009) 1.31
Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumors. J Cell Biochem (2004) 1.29
Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction. Blood (2008) 1.26
Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis. Mol Ther (2009) 1.24
Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells. J Biol Chem (2008) 1.24
Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase. J Biol Chem (2004) 1.24
Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2. J Neurochem (2008) 1.24
Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors. Stem Cells (2007) 1.22
The stem cell research environment: a patchwork of patchworks. Stem Cell Rev (2009) 1.21
Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. Cancer Res (2002) 1.20
HIF-1alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma. J Cell Sci (2003) 1.20
IDO-independent suppression of T cell effector function by IFN-γ-licensed human mesenchymal stromal cells. J Immunol (2014) 1.19
Identification and design of peptides as a new drug delivery system for the brain. J Pharmacol Exp Ther (2007) 1.18
Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells. Cell Stem Cell (2012) 1.16
The expression of rho proteins decreases with human brain tumor progression: potential tumor markers. Clin Exp Metastasis (2002) 1.16
Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine. J Immunol (2009) 1.15
Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation. Blood (2003) 1.15
Inhibition of cellular senescence by developmentally regulated FGF receptors in mesenchymal stem cells. Blood (2011) 1.10
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. J Neuroinflammation (2009) 1.10
Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis. Ann Neurol (2010) 1.08
P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. J Neurochem (2003) 1.07
High transcytosis of melanotransferrin (P97) across the blood-brain barrier. J Neurochem (2002) 1.07
Stem cell microvesicles transfer cystinosin to human cystinotic cells and reduce cystine accumulation in vitro. PLoS One (2012) 1.07
Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study. Exp Hematol (2002) 1.06
The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases. Biochemistry (2009) 1.06
Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties. Blood (2009) 1.06
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis (2005) 1.06
Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration. Exp Cell Res (2012) 1.05
Satellite DNA hypomethylation in karyotyped Wilms tumors. Cancer Genet Cytogenet (2003) 1.05
Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis (2005) 1.05
A DNA repeat, NBL2, is hypermethylated in some cancers but hypomethylated in others. Cancer Biol Ther (2005) 1.04
Plasminogen kringle 5-engineered glioma cells block migration of tumor-associated macrophages and suppress tumor vascularization and progression. Cancer Res (2005) 1.02
Malignant melanoma in childhood and adolescence: report of 13 cases. J Am Acad Dermatol (2005) 1.02
Roles of FGF signaling in stem cell self-renewal, senescence and aging. Aging (Albany NY) (2011) 1.02
IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity. Blood (2011) 1.02
Stem cell research ethics: consensus statement on emerging issues. J Obstet Gynaecol Can (2007) 1.02
Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier. Vascul Pharmacol (2002) 1.01
Green tea catechins as novel antitumor and antiangiogenic compounds. Curr Med Chem Anticancer Agents (2002) 1.01
Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Mol Nutr Food Res (2010) 1.01
Cardiac metastases from melanoma. Radiographics (2005) 1.00
Protein L-isoaspartyl methyltransferase repairs abnormal aspartyl residues accumulated in vivo in type-I collagen and restores cell migration. Exp Cell Res (2004) 1.00
Improved autograft survival of mesenchymal stromal cells by plasminogen activator inhibitor 1 inhibition. Stem Cells (2009) 1.00
Tumor environment dictates medulloblastoma cancer stem cell expression and invasive phenotype. Mol Cancer Res (2008) 0.99
Emerging concepts in the regulation of membrane-type 1 matrix metalloproteinase activity. Biochim Biophys Acta (2009) 0.99
Inhibition of cancer cell proliferation and suppression of TNF-induced activation of NFkappaB by edible berry juice. Anticancer Res (2007) 0.99
Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults. Cancer Chemother Pharmacol (2008) 0.99
Canadian guideline on genetic screening for hereditary renal cell cancers. Can Urol Assoc J (2013) 0.98
Ischemia injury alters endothelial cell properties of kidney cortex: stimulation of MMP-9. Exp Cell Res (2005) 0.98
Contribution of the 37-kDa laminin receptor precursor in the anti-metastatic PSP94-derived peptide PCK3145 cell surface binding. Biochem Biophys Res Commun (2006) 0.98
Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy. Hum Gene Ther (2004) 0.98
Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling. Mol Carcinog (2009) 0.97
Differential regulation of matrix metalloproteinase activities in abdominal aortic aneurysms. J Vasc Surg (2002) 0.97
Colorectal cancer prevention through dietary and lifestyle modifications. Cancer Microenviron (2011) 0.97
Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells. Cancer Res (2007) 0.97
Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy. Cancer Res (2004) 0.97
Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure. J Am Soc Nephrol (2006) 0.97
MSCs: science and trials. Nat Med (2013) 0.97
Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells. FEBS Lett (2007) 0.96