|
1
|
Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania: a randomized controlled trial.
|
Malar J
|
2008
|
2.22
|
|
2
|
Risk sharing arrangements for pharmaceuticals: potential considerations and recommendations for European payers.
|
BMC Health Serv Res
|
2010
|
2.21
|
|
3
|
Malaria rapid testing by community health workers is effective and safe for targeting malaria treatment: randomised cross-over trial in Tanzania.
|
PLoS One
|
2011
|
1.98
|
|
4
|
Clinical pharmacology in research, teaching and health care: Considerations by IUPHAR, the International Union of Basic and Clinical Pharmacology.
|
Basic Clin Pharmacol Toxicol
|
2010
|
1.96
|
|
5
|
Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response.
|
Nat Rev Drug Discov
|
2011
|
1.58
|
|
6
|
Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data.
|
Eur J Clin Pharmacol
|
2003
|
1.55
|
|
7
|
4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.
|
Pharmacogenet Genomics
|
2008
|
1.52
|
|
8
|
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community.
|
Trop Med Int Health
|
2005
|
1.39
|
|
9
|
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
|
Br J Clin Pharmacol
|
2009
|
1.33
|
|
10
|
Case management of malaria in under-fives at primary health care facilities in a Tanzanian district.
|
Trop Med Int Health
|
2002
|
1.32
|
|
11
|
Comparing policies to enhance prescribing efficiency in Europe through increasing generic utilization: changes seen and global implications.
|
Expert Rev Pharmacoecon Outcomes Res
|
2010
|
1.31
|
|
12
|
Multifaceted national and regional drug reforms and initiatives in ambulatory care in Sweden: global relevance.
|
Expert Rev Pharmacoecon Outcomes Res
|
2009
|
1.28
|
|
13
|
"Quality of prenatal and maternal care: bridging the know-do gap" (QUALMAT study): an electronic clinical decision support system for rural Sub-Saharan Africa.
|
BMC Med Inform Decis Mak
|
2013
|
1.24
|
|
14
|
SFINX-a drug-drug interaction database designed for clinical decision support systems.
|
Eur J Clin Pharmacol
|
2009
|
1.21
|
|
15
|
Policies to enhance prescribing efficiency in europe: findings and future implications.
|
Front Pharmacol
|
2011
|
1.19
|
|
16
|
Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles.
|
Biochem Biophys Res Commun
|
2005
|
1.15
|
|
17
|
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man.
|
Psychopharmacology (Berl)
|
2005
|
1.14
|
|
18
|
Forecasting drug utilization and expenditure in a metropolitan health region.
|
BMC Health Serv Res
|
2010
|
1.13
|
|
19
|
A new reimbursement system for innovative pharmaceuticals combining value-based and free market pricing.
|
Appl Health Econ Health Policy
|
2013
|
1.10
|
|
20
|
Data extraction from a semi-structured electronic medical record system for outpatients: a model to facilitate the access and use of data for quality control and research.
|
Health Informatics J
|
2009
|
1.09
|
|
21
|
Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes.
|
Br J Clin Pharmacol
|
2003
|
1.08
|
|
22
|
Personalizing health care: feasibility and future implications.
|
BMC Med
|
2013
|
1.07
|
|
23
|
'How to know what you need to do': a cross-country comparison of maternal health guidelines in Burkina Faso, Ghana and Tanzania.
|
Implement Sci
|
2012
|
1.06
|
|
24
|
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population.
|
Pharmacogenet Genomics
|
2006
|
1.06
|
|
25
|
Whose job is it anyway? Swedish general practitioners' perception of their responsibility for the patient's drug list.
|
Ann Fam Med
|
2010
|
1.06
|
|
26
|
Population pharmacokinetics of chloroquine and sulfadoxine and treatment response in children with malaria: suggestions for an improved dose regimen.
|
Br J Clin Pharmacol
|
2008
|
1.04
|
|
27
|
Ongoing measures to enhance the efficiency of prescribing of proton pump inhibitors and statins in The Netherlands: influence and future implications.
|
J Comp Eff Res
|
2012
|
1.04
|
|
28
|
Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania.
|
Trans R Soc Trop Med Hyg
|
2011
|
1.03
|
|
29
|
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study.
|
BMC Infect Dis
|
2013
|
1.00
|
|
30
|
Enhancing the rational use of new medicines across European health care systems.
|
Eur J Clin Pharmacol
|
2008
|
0.99
|
|
31
|
Recent national and regional drug reforms in Sweden: implications for pharmaceutical companies in Europe.
|
Pharmacoeconomics
|
2008
|
0.99
|
|
32
|
Dabigatran - a case history demonstrating the need for comprehensive approaches to optimize the use of new drugs.
|
Front Pharmacol
|
2013
|
0.95
|
|
33
|
Influence of demand-side measures to enhance renin-angiotensin prescribing efficiency in Europe: implications for the future.
|
Expert Rev Pharmacoecon Outcomes Res
|
2011
|
0.91
|
|
34
|
Are new models needed to optimize the utilization of new medicines to sustain healthcare systems?
|
Expert Rev Clin Pharmacol
|
2015
|
0.91
|
|
35
|
Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region--Bridging the gap between knowledge and practice.
|
Int J Med Inform
|
2006
|
0.90
|
|
36
|
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.
|
Eur J Clin Pharmacol
|
2003
|
0.89
|
|
37
|
The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.
|
Clin Pharmacol Ther
|
2002
|
0.89
|
|
38
|
The continuing challenge of providing drug information services to diminish the knowledge--practice gap in medical practice.
|
Eur J Clin Pharmacol
|
2013
|
0.88
|
|
39
|
Metabolism and elimination of quinine in healthy volunteers.
|
Eur J Clin Pharmacol
|
2003
|
0.88
|
|
40
|
Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden.
|
Pharmacogenetics
|
2002
|
0.87
|
|
41
|
Are prescribing initiatives readily transferable across classes: the case of generic losartan in Scotland?
|
Qual Prim Care
|
2013
|
0.87
|
|
42
|
Physicians' reported needs of drug information at point of care in Sweden.
|
Br J Clin Pharmacol
|
2012
|
0.86
|
|
43
|
Access and use of medicines information sources by physicians in public hospitals in Uganda: a cross-sectional survey.
|
Afr Health Sci
|
2008
|
0.85
|
|
44
|
The influence of a sustained multifaceted approach to improve antibiotic prescribing in Slovenia during the past decade: findings and implications.
|
Expert Rev Anti Infect Ther
|
2014
|
0.84
|
|
45
|
Field-adapted sampling of whole blood to determine the levels of amodiaquine and its metabolite in children with uncomplicated malaria treated with amodiaquine plus artesunate combination.
|
Malar J
|
2009
|
0.84
|
|
46
|
A study of adherence to drug recommendations by providing feedback of outpatient prescribing patterns to hospital specialists.
|
Pharmacoepidemiol Drug Saf
|
2005
|
0.83
|
|
47
|
Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations.
|
Eur J Clin Pharmacol
|
2013
|
0.83
|
|
48
|
Potential to enhance the prescribing of generic drugs in patients with mental health problems in austria; implications for the future.
|
Front Pharmacol
|
2013
|
0.82
|
|
49
|
Janus computerised prescribing system provides pharmacological knowledge at point of care - design, development and proof of concept.
|
Eur J Clin Pharmacol
|
2006
|
0.82
|
|
50
|
e-SPC - delivering drug information in the 21st century: developing new approaches to deliver drug information to prescribers.
|
Br J Clin Pharmacol
|
2012
|
0.82
|
|
51
|
Cytochrome P450-mediated changes in oxycodone pharmacokinetics/pharmacodynamics and their clinical implications.
|
Drugs
|
2013
|
0.82
|
|
52
|
Ongoing initiatives in the Republic of Srpska to enhance prescribing efficiency: influence and future directions.
|
Expert Rev Pharmacoecon Outcomes Res
|
2012
|
0.82
|
|
53
|
Extraction of electronic health record data in a hospital setting: comparison of automatic and semi-automatic methods using anti-TNF therapy as model.
|
Basic Clin Pharmacol Toxicol
|
2013
|
0.82
|
|
54
|
A cross-sectional pilot study assessing needs and attitudes to implementation of Information and Communication Technology for rational use of medicines among healthcare staff in rural Tanzania.
|
BMC Med Inform Decis Mak
|
2014
|
0.81
|
|
55
|
Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women.
|
Eur J Clin Pharmacol
|
2010
|
0.81
|
|
56
|
Changes in the utilization of venlafaxine after the introduction of generics in Sweden.
|
Appl Health Econ Health Policy
|
2013
|
0.80
|
|
57
|
HIV/AIDS patients display lower relative bioavailability of efavirenz than healthy subjects.
|
Clin Pharmacokinet
|
2011
|
0.80
|
|
58
|
Variations in understanding the drug-prescribing process: a qualitative study among Swedish GPs.
|
Fam Pract
|
2008
|
0.80
|
|
59
|
Multilevel analysis of the influence of patients' and general practitioners' characteristics on patented versus multiple-sourced statin prescribing in France.
|
Appl Health Econ Health Policy
|
2013
|
0.79
|
|
60
|
Access to up-to-date drug information in developing countries continues to pose problems: the case of Uganda.
|
Pharmacoepidemiol Drug Saf
|
2007
|
0.79
|
|
61
|
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.
|
Ther Drug Monit
|
2010
|
0.79
|
|
62
|
Existence of antimalarial formulations with low bioavailability in Tanzania.
|
Trop Doct
|
2006
|
0.79
|
|
63
|
Rectal ropivacaine is absorbed proportionally to the dose, with low intraindividual variability.
|
Br J Clin Pharmacol
|
2003
|
0.78
|
|
64
|
Imperative to consider multiple initiatives to maximize prescribing efficiency from generic availability: case history from Abu Dhabi.
|
Expert Rev Pharmacoecon Outcomes Res
|
2012
|
0.78
|
|
65
|
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.
|
Drug Metab Dispos
|
2002
|
0.78
|
|
66
|
Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of alpha- and 4-hydroxy metabolites in healthy subjects.
|
Eur J Clin Pharmacol
|
2005
|
0.77
|
|
67
|
Interferon-beta treatment in patients with multiple sclerosis does not alter CYP2C19 or CYP2D6 activity.
|
Br J Clin Pharmacol
|
2003
|
0.76
|
|
68
|
Quality indicators as a tool in improving the introduction of new medicines.
|
Basic Clin Pharmacol Toxicol
|
2014
|
0.76
|
|
69
|
Review of ongoing initiatives to improve prescribing efficiency in China; angiotensin receptor blockers as a case history.
|
Expert Rev Pharmacoecon Outcomes Res
|
2014
|
0.76
|
|
70
|
Quantification of valproic acid in dried blood spots.
|
Scand J Clin Lab Invest
|
2014
|
0.75
|
|
71
|
[Electronic support in the medical record for drug dosage in renal failure].
|
Lakartidningen
|
2015
|
0.75
|
|
72
|
[Clinical decision support can provide assistance in complex health care].
|
Lakartidningen
|
2015
|
0.75
|
|
73
|
Comparable lumefantrine oral bioavailability when co-administered with oil-fortified maize porridge or milk in healthy volunteers.
|
Basic Clin Pharmacol Toxicol
|
2013
|
0.75
|
|
74
|
Drugs and Birth Defects: a knowledge database providing risk assessments based on national health registers.
|
Eur J Clin Pharmacol
|
2012
|
0.75
|
|
75
|
[Red yeast rice can lower cholesterol but should not replace established therapy].
|
Lakartidningen
|
2012
|
0.75
|
|
76
|
[Healthcare IT systems and doctors' influence].
|
Lakartidningen
|
2015
|
0.75
|
|
77
|
[Contradictory whether paracetamol is contraindicated after childhood vaccination].
|
Lakartidningen
|
2013
|
0.75
|
|
78
|
An analytical framework for assessing drug and therapeutics committee structure and work processes in tertiary Brazilian hospitals.
|
Basic Clin Pharmacol Toxicol
|
2014
|
0.75
|
|
79
|
[Following a Lex Maria case: safe computer support systems for drug prescription required].
|
Lakartidningen
|
2008
|
0.75
|
|
80
|
[Efficient and safe drug therapy requires better IT systems. A survey among the chairmen of the Swedish Drug and Therapeutics Committees reveals shortages].
|
Lakartidningen
|
2010
|
0.75
|
|
81
|
Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo.
|
Eur J Clin Pharmacol
|
2006
|
0.75
|
|
82
|
High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2003
|
0.75
|