Glomerular number and size in autopsy kidneys: the relationship to birth weight.

PubWeight™: 2.40‹?› | Rank: Top 2%

🔗 View Article (PMID 12753298)

Published in Kidney Int on June 01, 2003

Authors

Michael Hughson1, Alton B Farris, Rebecca Douglas-Denton, Wendy E Hoy, John F Bertram

Author Affiliations

1: University of Mississippi Medical Center, Jackson, Mississippi 39216-4505, USA. mhughsn@pathology.umsmed.edu

Articles citing this

(truncated to the top 100)

Human nephron number: implications for health and disease. Pediatr Nephrol (2011) 2.03

Mammalian kidney development: principles, progress, and projections. Cold Spring Harb Perspect Biol (2012) 1.80

Low birth weight increases risk for end-stage renal disease. J Am Soc Nephrol (2007) 1.57

Safety in glomerular numbers. Pediatr Nephrol (2012) 1.49

Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy. Pediatr Nephrol (2009) 1.45

The association of poverty with the prevalence of albuminuria: data from the Third National Health and Nutrition Examination Survey (NHANES III). Am J Kidney Dis (2006) 1.36

A common RET variant is associated with reduced newborn kidney size and function. J Am Soc Nephrol (2008) 1.24

Defining and redefining the nephron progenitor population. Pediatr Nephrol (2011) 1.23

Role of the kidney in the prenatal and early postnatal programming of hypertension. Am J Physiol Renal Physiol (2009) 1.21

Association of kidney function and metabolic risk factors with density of glomeruli on renal biopsy samples from living donors. Mayo Clin Proc (2011) 1.15

Adult height and the risk of cardiovascular disease among middle aged men and women in Japan. Eur J Epidemiol (2010) 1.09

Nephron hypertrophy and glomerulosclerosis and their association with kidney function and risk factors among living kidney donors. Clin J Am Soc Nephrol (2014) 1.09

Nutritional programming of disease: unravelling the mechanism. J Anat (2008) 1.07

Kidneys - kindergarten to graduation. Indian J Nephrol (2016) 1.06

Obesity and preterm birth: additive risks in the progression of kidney disease in children. Pediatr Nephrol (2009) 1.03

Renal stem cells: fact or science fiction? Biochem J (2012) 1.02

Determinants and functional significance of renal parenchymal volume in adults. Clin J Am Soc Nephrol (2010) 1.02

Proximal nephron. Compr Physiol (2013) 1.02

Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production. BMC Dev Biol (2011) 1.02

Hypertension, glomerular hypertrophy and nephrosclerosis: the effect of race. Nephrol Dial Transplant (2013) 1.01

How the kidney is impacted by the perinatal maternal environment to develop hypertension. Biol Reprod (2013) 0.99

Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations. Nephrol Dial Transplant (2010) 0.99

Comparative renal histomorphometry: a case study of oligonephropathy of prematurity. Pediatr Nephrol (2005) 0.98

Regenerative medicine for the kidney: stem cell prospects & challenges. Clin Transl Med (2013) 0.98

Reduced renal length and volume 20 years after very preterm birth. Pediatr Nephrol (2009) 0.98

Renal pathology, glomerular number and volume in a West African urban community. Nephrol Dial Transplant (2008) 0.97

Nephron number and individual glomerular volumes in male Caucasian and African American subjects. Nephrol Dial Transplant (2009) 0.97

Detection and Clinical Patterns of Nephron Hypertrophy and Nephrosclerosis Among Apparently Healthy Adults. Am J Kidney Dis (2016) 0.97

The long-term effects of prematurity and intrauterine growth restriction on cardiovascular, renal, and metabolic function. Int J Pediatr (2010) 0.96

Ouabain protects against adverse developmental programming of the kidney. Nat Commun (2010) 0.95

Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure. Am J Hypertens (2010) 0.95

The relationship between nephron number, kidney size and body weight in two inbred mouse strains. Organogenesis (2011) 0.93

Gender differences in developmental programming of cardiovascular diseases. Clin Sci (Lond) (2016) 0.93

Maternal diabetes programs hypertension and kidney injury in offspring. Pediatr Nephrol (2010) 0.93

Differential effects of clinical doses of antenatal betamethasone on nephron endowment and glomerular filtration rate in adult sheep. Reprod Sci (2009) 0.93

Serum creatinine levels are significantly influenced by renal size in the normal pediatric population. Clin J Am Soc Nephrol (2010) 0.92

No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers. Pediatr Nephrol (2010) 0.91

Kidney disease in Aboriginal Australians: a perspective from the Northern Territory. Clin Kidney J (2014) 0.91

The Substantial Loss of Nephrons in Healthy Human Kidneys with Aging. J Am Soc Nephrol (2016) 0.90

Early influences on cardiovascular and renal development. Eur J Epidemiol (2010) 0.90

Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br/+ adult mice. Am J Physiol Renal Physiol (2009) 0.90

Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33. Am J Hum Genet (2007) 0.90

Podocyte Number in Children and Adults: Associations with Glomerular Size and Numbers of Other Glomerular Resident Cells. J Am Soc Nephrol (2015) 0.89

Sex differences in the developmental origins of cardiovascular disease. Physiology (Bethesda) (2014) 0.89

Relationship between adult height and body weight and risk of carotid atherosclerosis assessed in terms of carotid intima-media thickness: the Nagasaki Islands study. J Physiol Anthropol (2013) 0.89

Assessment of long-term renal complications in extremely low birth weight children. Pediatr Nephrol (2011) 0.89

Fetal programming and cardiovascular pathology. Compr Physiol (2015) 0.88

Estimating individual glomerular volume in the human kidney: clinical perspectives. Nephrol Dial Transplant (2011) 0.87

Low Birth Weight due to Intrauterine Growth Restriction and/or Preterm Birth: Effects on Nephron Number and Long-Term Renal Health. Int J Nephrol (2012) 0.86

Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function. J Physiol (2011) 0.86

Developmental origins of chronic renal disease: an integrative hypothesis. Int J Nephrol (2013) 0.86

Renal agenesis and unilateral nephrectomy: what are the risks of living with a single kidney? Pediatr Nephrol (2008) 0.85

Low nephron number and its clinical consequences. Rambam Maimonides Med J (2011) 0.85

Adverse consequences of accelerated neonatal growth: cardiovascular and renal issues. Pediatr Nephrol (2010) 0.85

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development (2016) 0.84

Vitamin D deficiency during pregnancy and lactation stimulates nephrogenesis in rat offspring. Pediatr Nephrol (2007) 0.84

Factors associated with a vicious cycle involving a low nephron number, hypertension and chronic kidney disease. Hypertens Res (2015) 0.83

Low nephron number--a new cardiovascular risk factor in children? Pediatr Nephrol (2004) 0.83

Chronic partial ureteral obstruction and the developing kidney. Pediatr Radiol (2007) 0.83

Maternal smoking during pregnancy and kidney volume in the offspring: the Generation R Study. Pediatr Nephrol (2011) 0.82

The Impact of Kidney Development on the Life Course: A Consensus Document for Action. Nephron (2017) 0.82

Renal hypoplasia: lessons from Pax2. Pediatr Nephrol (2005) 0.82

Age-related pathophysiological changes in rat oligomeganephronic hypoplastic kidney. Pediatr Nephrol (2006) 0.82

Predicting the outcome of chronic kidney disease by the estimated nephron number: the rationale and design of PRONEP, a prospective, multicenter, observational cohort study. BMC Nephrol (2012) 0.81

Developmental cigarette smoke exposure: kidney proteome profile alterations in low birth weight pups. Toxicology (2012) 0.81

Fetal exposure to maternal type 1 diabetes is associated with renal dysfunction at adult age. Diabetes (2010) 0.81

Clinicopathological assessment of the nephron number. Clin Kidney J (2014) 0.81

Metabolic programming during lactation stimulates renal Na+ transport in the adult offspring due to an early impact on local angiotensin II pathways. PLoS One (2011) 0.81

The association of predonation hypertension with glomerular function and number in older living kidney donors. J Am Soc Nephrol (2014) 0.81

Low birth weight and end-stage renal disease: demographic analysis by region in Japan. Clin Exp Nephrol (2012) 0.81

The cardio-protective diet. Indian J Med Res (2010) 0.81

Nephron number and its determinants in early life: a primer. Pediatr Nephrol (2014) 0.81

Birth Weight and Birth Weight for Gestational Age in Relation to Risk of Hospitalization with Primary Hypertension in Children and Young Adults. Matern Child Health J (2016) 0.80

Birth parameters and parental height predict growth outcome in children with chronic kidney disease. Pediatr Nephrol (2013) 0.80

Early life obesity and chronic kidney disease in later life. Pediatr Nephrol (2014) 0.80

Glomerular hypertrophy in subjects with low nephron number: contributions of sex, body size and race. Nephrol Dial Transplant (2014) 0.80

Increased urinary angiotensinogen is an effective marker of chronic renal impairment in very low birth weight children. Clin Exp Nephrol (2013) 0.80

Race-specific relationship of birth weight and renal function among healthy young children. Pediatr Nephrol (2012) 0.80

The path to chronic kidney disease following acute kidney injury: a neonatal perspective. Pediatr Nephrol (2016) 0.80

Counting glomeruli and podocytes: rationale and methodologies. Curr Opin Nephrol Hypertens (2015) 0.80

Mechanisms of fetal programming in hypertension. Int J Pediatr (2012) 0.79

A comparison of pathomolecular markers of fibrosis and morphology in kidney from autopsies of African Americans and whites. Virchows Arch (2006) 0.79

Childhood kidney outcomes in relation to fetal blood flow and kidney size. J Am Soc Nephrol (2014) 0.79

Altered ureteric branching morphogenesis and nephron endowment in offspring of diabetic and insulin-treated pregnancy. PLoS One (2013) 0.79

Kidney disease in children: latest advances and remaining challenges. Nat Rev Nephrol (2016) 0.78

Glomerular Density and Volume in Renal Biopsy Specimens of Children with Proteinuria Relative to Preterm Birth and Gestational Age. Clin J Am Soc Nephrol (2017) 0.78

Impact of gestational age and birth weight on amikacin clearance on day 1 of life. Clin J Am Soc Nephrol (2009) 0.78

Glomerular structural-functional relationship models of diabetic nephropathy are robust in type 1 diabetic patients. Nephrol Dial Transplant (2014) 0.78

Low birth weight, but not postnatal weight gain, aggravates the course of nephrotic syndrome. Pediatr Nephrol (2007) 0.78

Reduction in maternal circulating ouabain impairs offspring growth and kidney development. J Am Soc Nephrol (2014) 0.78

Morphometric analysis of nonsclerosed Glomeruli size and connective tissue content during the aging process. ScientificWorldJournal (2012) 0.78

Suckling a protein-restricted rat dam leads to diminished albuminuria in her male offspring in adult life: a longitudinal study. BMC Nephrol (2006) 0.78

Pathological similarities between low birth weight-related nephropathy and nephropathy associated with mitochondrial cytopathy. Diagn Pathol (2014) 0.78

Prognostic factors and biomarkers of congenital obstructive nephropathy. Pediatr Nephrol (2015) 0.77

Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation. Am J Physiol Renal Physiol (2015) 0.77

Elevated levels of protein in urine in adulthood after exposure to the Chinese famine of 1959-61 during gestation and the early postnatal period. Int J Epidemiol (2014) 0.77

Renal function and klotho gene polymorphisms among Uygur and Kazak populations in Xinjiang, China. Med Sci Monit (2015) 0.77

Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age. Pediatr Nephrol (2012) 0.77

Urinary vitamin A excretion in very low birth weight infants. Pediatr Nephrol (2008) 0.77

1H-NMR metabolic profiling of human neonatal urine. MAGMA (2006) 0.77

Articles by these authors

Patterns of mortality in Indigenous adults in the Northern Territory, 1998-2003: are people living in more remote areas worse off? Med J Aust (2009) 3.39

A data model and database for high-resolution pathology analytical image informatics. J Pathol Inform (2011) 2.54

Biomarkers in chronic kidney disease: a review. Kidney Int (2011) 2.25

Human nephron number: implications for health and disease. Pediatr Nephrol (2011) 2.03

Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol (2009) 2.01

A stereological study of glomerular number and volume: preliminary findings in a multiracial study of kidneys at autopsy. Kidney Int Suppl (2003) 1.90

A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expr Patterns (2007) 1.77

Is the Framingham coronary heart disease absolute risk function applicable to Aboriginal people? Med J Aust (2005) 1.76

Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease. Lancet (2013) 1.73

Overlapping pathways to transplant glomerulopathy: chronic humoral rejection, hepatitis C infection, and thrombotic microangiopathy. Kidney Int (2011) 1.73

Role of microRNAs in kidney homeostasis and disease. Kidney Int (2012) 1.72

Development of focal segmental glomerulosclerosis after anabolic steroid abuse. J Am Soc Nephrol (2009) 1.70

Is there such a thing as a renal stem cell? J Am Soc Nephrol (2009) 1.61

Nephron number, hypertension, renal disease, and renal failure. J Am Soc Nephrol (2005) 1.57

Renal biopsy findings among Indigenous Australians: a nationwide review. Kidney Int (2012) 1.56

A comparison of nephron number, glomerular volume and kidney weight in Senegalese Africans and African Americans. Nephrol Dial Transplant (2010) 1.56

Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy. Diabetes (2010) 1.48

Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. J Am Soc Nephrol (2005) 1.40

The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis. Stem Cells (2006) 1.40

Nephron number, renal function, and arterial pressure in aged GDNF heterozygous mice. Hypertension (2003) 1.37

Prenatal corticosterone exposure results in altered AT1/AT2, nephron deficit and hypertension in the rat offspring. J Physiol (2007) 1.34

Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3. Am J Pathol (2010) 1.33

Accelerated maturation and abnormal morphology in the preterm neonatal kidney. J Am Soc Nephrol (2011) 1.31

In vitro differentiation of murine embryonic stem cells toward a renal lineage. Differentiation (2007) 1.31

Determinants of glomerular volume in different cortical zones of the human kidney. J Am Soc Nephrol (2005) 1.31

Nephron number, glomerular volume, renal disease and hypertension. Curr Opin Nephrol Hypertens (2008) 1.30

Associations of glomerular number and birth weight with clinicopathological features of African Americans and whites. Am J Kidney Dis (2008) 1.30

Renal cilia display length alterations following tubular injury and are present early in epithelial repair. Nephrol Dial Transplant (2007) 1.28

Does nephron number matter in the development of kidney disease? Ethn Dis (2006) 1.19

Measuring glomerular number and size in perfused kidneys using MRI. Am J Physiol Renal Physiol (2011) 1.15

Kidney volume, blood pressure, and albuminuria: findings in an Australian aboriginal community. Am J Kidney Dis (2004) 1.14

Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia. Am J Physiol Renal Physiol (2009) 1.12

Review: Endothelial-myofibroblast transition, a new player in diabetic renal fibrosis. Nephrology (Carlton) (2010) 1.11

Fidelity and evolution of recurrent FSGS in renal allografts. J Am Soc Nephrol (2008) 1.11

Glomerular number and size variability and risk for kidney disease. Curr Opin Nephrol Hypertens (2011) 1.10

Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol (2009) 1.10

Quantification of glomerular number and size distribution in normal rat kidneys using magnetic resonance imaging. Nephrol Dial Transplant (2011) 1.10

Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy. PLoS One (2013) 1.10

Augmented and accelerated nephrogenesis in TGF-beta2 heterozygous mutant mice. Pediatr Res (2008) 1.09

Three-dimensional imaging reveals ureteric and mesenchymal defects in Fgfr2-mutant kidneys. J Am Soc Nephrol (2009) 1.08

Renal function and cardiovascular risk markers in a remote Australian Aboriginal community. Nephrol Dial Transplant (2003) 1.07

Genetic research in Indigenous health: significant progress, substantial challenges. Med J Aust (2012) 1.07

Compensatory renal growth after unilateral nephrectomy in the ovine fetus. J Am Soc Nephrol (2002) 1.06

Combined prenatal and postnatal protein restriction influences adult kidney structure, function, and arterial pressure. Am J Physiol Regul Integr Comp Physiol (2006) 1.05

CKD.QLD: chronic kidney disease surveillance and research in Queensland, Australia. Nephrol Dial Transplant (2012) 1.05

A stereological study of the renal glomerular vasculature in the db/db mouse model of diabetic nephropathy. J Anat (2005) 1.04

Glomerular size and glomerulosclerosis: relationships to disease categories, glomerular solidification, and ischemic obsolescence. Am J Kidney Dis (2002) 1.03

Effects of dietary protein restriction on nephron number in the mouse. Am J Physiol Regul Integr Comp Physiol (2007) 1.02

Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors. Stem Cells Dev (2010) 1.02

Validation of self-reported cigarette smoking in a remote Australian Aboriginal community. Aust N Z J Public Health (2003) 1.02

Is nephrogenesis affected by preterm birth? Studies in a non-human primate model. Am J Physiol Renal Physiol (2009) 1.01

Exogenous BMP-4 amplifies asymmetric ureteric branching in the developing mouse kidney in vitro. Kidney Int (2005) 1.01

Estimation of glomerular podocyte number: a selection of valid methods. J Am Soc Nephrol (2013) 1.00

CKD in Aboriginal Australians. Am J Kidney Dis (2010) 0.99

Bone morphogenetic protein signaling in the developing kidney: present and future. Differentiation (2008) 0.99

Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations. Nephrol Dial Transplant (2010) 0.99

The role of heat shock protein 70 in mediating age-dependent mortality in sepsis. J Immunol (2011) 0.98

Incidence of type 2 diabetes in Aboriginal Australians: an 11-year prospective cohort study. BMC Public Health (2010) 0.98

Albuminuria and incident coronary heart disease in Australian Aboriginal people. Kidney Int (2005) 0.98

Accurate assessment of kidney function in indigenous Australians: the estimated GFR study. Am J Kidney Dis (2012) 0.98

Nephron number and individual glomerular volumes in male Caucasian and African American subjects. Nephrol Dial Transplant (2009) 0.97

Renal pathology, glomerular number and volume in a West African urban community. Nephrol Dial Transplant (2008) 0.97

Cost-effectiveness analysis of a kidney and cardiovascular disease treatment program in an Australian Aboriginal population. Adv Chronic Kidney Dis (2005) 0.96

Anthropometric measurements of Australian Aboriginal adults living in remote areas: comparison with nationally representative findings. Am J Hum Biol (2008) 0.96

Chronic alcohol ingestion increases mortality and organ injury in a murine model of septic peritonitis. PLoS One (2013) 0.96

Disorders of glucose regulation in adults and birth weight: results from the Australian Diabetes, Obesity and Lifestyle (AUSDIAB) Study. Diabetes Care (2007) 0.94

Is there an association between level of adult blood pressure and nephron number or renal filtration surface area? Kidney Int (2004) 0.94

Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney. Kidney Int (2005) 0.94

The where, what and why of the developing renal stroma. Nephron Exp Nephrol (2005) 0.94

Association between diabetes and coronary heart disease in Aboriginal people: are women disadvantaged? Med J Aust (2004) 0.94

Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer. Cancer Lett (2013) 0.94

The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma. Mod Pathol (2011) 0.93

Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity. J Immunol (2011) 0.93

Estimating total nephron number in the adult kidney using the physical disector/fractionator combination. Methods Mol Biol (2012) 0.93

Distribution of volumes of individual glomeruli in kidneys at autopsy: association with physical and clinical characteristics and with ethnic group. Am J Nephrol (2011) 0.93

Betaglycan is required for the establishment of nephron endowment in the mouse. PLoS One (2011) 0.93

The emerging role of MRI in quantitative renal glomerular morphology. Am J Physiol Renal Physiol (2013) 0.93

Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns (2006) 0.92

Cecal ligation and puncture followed by methicillin-resistant Staphylococcus aureus pneumonia increases mortality in mice and blunts production of local and systemic cytokines. Shock (2012) 0.92

Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis. J Am Soc Nephrol (2006) 0.91

Hypertension, dyslipidemia, body mass index, diabetes and smoking status in Aboriginal Australians in a remote community. Ethn Dis (2003) 0.91

White adipocytes: more than just fat depots. Int J Biochem Cell Biol (2011) 0.91

Associations between age, body size and nephron number with individual glomerular volumes in urban West African males. Nephrol Dial Transplant (2008) 0.91

Clinically relevant biomarkers to select patients for targeted inhibitor therapy after resection of hepatocellular carcinoma. Ann Surg Oncol (2011) 0.91

The association between birthweight and current blood pressure: a cross-sectional study in an Australian Aboriginal community. Med J Aust (2003) 0.91