Published in Drug Metab Dispos on June 01, 2003
Aspergillus infections in transplant recipients. Clin Microbiol Rev (2005) 2.82
Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients. Antimicrob Agents Chemother (2008) 1.69
Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology. J Antimicrob Chemother (2013) 1.63
Species-specific antifungal susceptibility patterns of Scedosporium and Pseudallescheria species. Antimicrob Agents Chemother (2012) 1.62
Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype. Br J Clin Pharmacol (2009) 1.49
Impact of cyp51A mutations on the pharmacokinetic and pharmacodynamic properties of voriconazole in a murine model of disseminated aspergillosis. Antimicrob Agents Chemother (2010) 1.49
Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture. Antimicrob Agents Chemother (2008) 1.47
Observational study of the clinical efficacy of voriconazole and its relationship to plasma concentrations in patients. Antimicrob Agents Chemother (2011) 1.41
Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins. Antimicrob Agents Chemother (2008) 1.38
Tissue penetration of antifungal agents. Clin Microbiol Rev (2014) 1.13
Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspofungin. Antimicrob Agents Chemother (2010) 1.11
Variability of voriconazole plasma levels measured by new high-performance liquid chromatography and bioassay methods. Antimicrob Agents Chemother (2006) 1.09
Efficacy of caspofungin and voriconazole combinations in experimental aspergillosis. Antimicrob Agents Chemother (2005) 1.08
Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A. Antimicrob Agents Chemother (2008) 1.08
In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3. Drug Metab Dispos (2010) 1.08
Intrapulmonary penetration of voriconazole in patients receiving an oral prophylactic regimen. Antimicrob Agents Chemother (2006) 1.06
Accelerated metabolism of voriconazole and its partial reversal by cimetidine. Antimicrob Agents Chemother (2009) 1.05
Detection of Aspergillus DNA in cerebrospinal fluid from patients with cerebral aspergillosis by a nested PCR assay. J Clin Microbiol (2006) 1.02
Combination therapy of advanced invasive pulmonary aspergillosis in transiently neutropenic rats using human pharmacokinetic equivalent doses of voriconazole and anidulafungin. Antimicrob Agents Chemother (2009) 1.01
Inflammation is associated with voriconazole trough concentrations. Antimicrob Agents Chemother (2014) 1.00
Pharmacokinetic interactions of efavirenz and voriconazole in healthy volunteers. Br J Clin Pharmacol (2008) 1.00
Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes. Drug Metab Dispos (2008) 0.95
Voriconazole pharmacokinetics in liver transplant recipients. Antimicrob Agents Chemother (2009) 0.92
A reference laboratory experience of clinically achievable voriconazole, posaconazole, and itraconazole concentrations within the bloodstream and cerebral spinal fluid. Antimicrob Agents Chemother (2013) 0.89
Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery. AAPS J (2008) 0.89
Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging. Antimicrob Agents Chemother (2013) 0.88
Therapeutic drug monitoring for triazoles: A needs assessment review and recommendations from a Canadian perspective. Can J Infect Dis Med Microbiol (2015) 0.85
Evaluation of intravenous voriconazole in patients with compromised renal function. BMC Infect Dis (2013) 0.85
Efficacy of voriconazole in a guinea pig model of invasive trichosporonosis. Antimicrob Agents Chemother (2006) 0.84
Altered pharmacokinetics of voriconazole in a patient with liver cirrhosis. Antimicrob Agents Chemother (2007) 0.84
Steady-state pharmacokinetics of oral voriconazole and its primary metabolite, N-oxide voriconazole, pre- and post-autologous peripheral stem cell transplantation. Antimicrob Agents Chemother (2013) 0.84
Voriconazole Enhances the Osteogenic Activity of Human Osteoblasts In Vitro through a Fluoride-Independent Mechanism. Antimicrob Agents Chemother (2015) 0.83
The pharmacokinetics of voriconazole. Br J Clin Pharmacol (2003) 0.83
Concentrations of voriconazole in healthy and inflamed lung in rats. Antimicrob Agents Chemother (2009) 0.82
In vivo efficacy and pharmacokinetics of voriconazole in an animal model of dermatophytosis. Antimicrob Agents Chemother (2007) 0.81
Painful periostitis in the setting of chronic voriconazole therapy. Proc (Bayl Univ Med Cent) (2014) 0.80
The effects of caspofungin and voriconazole in an experimental fungal infection of the ear due to Aspergillus. Eur Arch Otorhinolaryngol (2009) 0.79
Pharmacokinetics of oral terbinafine in horses and Greyhound dogs. J Vet Pharmacol Ther (2011) 0.79
Impact of hypoalbuminemia on voriconazole pharmacokinetics in critically ill adult patients. Antimicrob Agents Chemother (2014) 0.79
Efficacy of triazoles in a murine disseminated infection by Candida krusei. Antimicrob Agents Chemother (2009) 0.78
Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice. Antimicrob Agents Chemother (2012) 0.78
Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations. Antimicrob Agents Chemother (2016) 0.78
Intravenous voriconazole after toxic oral administration. Antimicrob Agents Chemother (2010) 0.77
Evaluation of In Vitro Cytochrome P450 Inhibition and In Vitro Fate of Structurally Diverse N-Oxide Metabolites: Case Studies with Clozapine, Levofloxacin, Roflumilast, Voriconazole and Zopiclone. Eur J Drug Metab Pharmacokinet (2016) 0.76
PharmGKB summary: voriconazole pathway, pharmacokinetics. Pharmacogenet Genomics (2017) 0.75
Effect of various anticoagulants on the bioanalysis of drugs in rat blood: implication for pharmacokinetic studies of anticancer drugs. Springerplus (2016) 0.75
Optimization of polyene-azole combination therapy against aspergillosis using an in vitro pharmacokinetic-pharmacodynamic model. Antimicrob Agents Chemother (2015) 0.75
Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole. J Clin Pharmacol (2015) 0.75
Comparative evaluation of the predictive performance of three different structural population pharmacokinetic models to predict future voriconazole concentrations. Antimicrob Agents Chemother (2016) 0.75
Influence of Experimental Cryptococcal Meningitis in Wistar Rats on Voriconazole Brain Penetration Assessed by Microdialysis. Antimicrob Agents Chemother (2017) 0.75
Auto-inhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics. Br J Clin Pharmacol (2017) 0.75
Nucleotide sequence of the AIDS virus, LAV. Cell (1985) 16.81
Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis. Lancet (1993) 16.75
Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science (1992) 16.31
The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature (1992) 11.99
Patient satisfaction: a review of issues and concepts. Soc Sci Med (1997) 8.69
Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus. Cell (1985) 7.86
Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac. Biochemistry (1971) 6.10
Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. J Virol (2009) 4.40
Rapid Mycobacterium species assignment and unambiguous identification of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis by automated DNA sequencing. Arch Pathol Lab Med (1995) 4.10
Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment. JAMA (2001) 3.90
Response rate in patient satisfaction research: an analysis of 210 published studies. Int J Qual Health Care (1998) 3.78
Chance and consensus in peer review. Science (1981) 3.77
Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products. Biochem J (1988) 3.66
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med (1995) 3.64
The genetics of bacterial spore germination. Annu Rev Microbiol (1990) 3.57
HIV infection and South-West general practitioners. J R Soc Health (1989) 3.49
Pharmacokinetics and safety of voriconazole following intravenous- to oral-dose escalation regimens. Antimicrob Agents Chemother (2002) 3.40
Single-molecule biomechanics with optical methods. Science (1999) 3.35
The challenge of tuberculosis: statements on global control and prevention. Lancet (1995) 3.19
Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole. Drug Metab Dispos (2003) 2.91
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations. Br J Pharmacol (1982) 2.83
Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nat Genet (1997) 2.77
Maternal smoking and childhood asthma. Pediatrics (1990) 2.71
Regulation of methionine synthesis in Salmonella typhimurium: mutants resistant to inhibition by analogues of methionine. Genetics (1968) 2.62
Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. J Cell Biol (1993) 2.48
Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut (2010) 2.47
Cesarean section delivery in the 1980s: international comparison by indication. Am J Obstet Gynecol (1994) 2.45
Inherited deficiency of the second component of complement. Rheumatic disease associations. J Clin Invest (1976) 2.38
Oxytocin receptor antagonists for inhibiting preterm labour. Cochrane Database Syst Rev (2005) 2.36
A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer. Radiother Oncol (1997) 2.35
Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2. Neurology (2008) 2.31
Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters. J Gen Virol (1987) 2.27
Genetics analysis of spore germination mutants of Bacillus subtilis 168: the correlation of phenotype with map location. J Gen Microbiol (1979) 2.26
Perceptions and reactions of the public to diarrhoea. J R Soc Health (1993) 2.22
Effects of I.C.I. 50172 in man during erect exercise. Br Med J (1968) 2.22
Issues involved in the definition and classification of chronic health conditions. Pediatrics (1993) 2.17
Methionine genes and enzymes of Salmonella typhimurium. Heredity (Edinb) (1966) 2.11
Home standards of sterilization of infant feeding bottles and teats. Mon Bull Minist Health Public Health Lab Serv (1966) 2.10
The informative process in private medical consultations: a preliminary investigation. Soc Sci Med (1978) 2.03
Clinical significance of positive inotropic action of digoxin in patients with left ventricular disease. Br Heart J (1973) 2.02
Chronic conditions, socioeconomic risks, and behavioral problems in children and adolescents. Pediatrics (1990) 2.01
Range of mental illness among the elderly in the community. Prevalence in Liverpool using the GMS-AGECAT package. Br J Psychiatry (1987) 1.96
Is a rising caesarean section rate inevitable? Br J Obstet Gynaecol (1998) 1.87
Flat affect in schizophrenia does not reflect diminished subjective experience of emotion. J Abnorm Psychol (1993) 1.83
Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. Brain (2003) 1.82
The right ventricular infundibulum: has it a role? Eur J Echocardiogr (2003) 1.81
Scientific output and recognition: a study in the operation of the reward system in science. Am Sociol Rev (1967) 1.78
The 'rapid filling wave' of the apex cardiogram. Its relation to echocardiographic and cineangiographic measurements of ventricular filling. Br Heart J (1975) 1.75
Autophagic vacuoles in experimental atrophy. Exp Mol Pathol (1971) 1.75
Spina bifida and anencephaly in Scotland. Br Med J (Clin Res Ed) (1984) 1.75
Detection of 16 gamma-ray pulsars through blind frequency searches using the Fermi LAT. Science (2009) 1.74
Parental smoking and the risk of childhood asthma. Am J Public Health (1982) 1.73
Phospholipid binding properties of human placental anticoagulant protein-I, a member of the lipocortin family. J Biol Chem (1989) 1.72
Relation of isovolumic relaxation to left ventricular wall movement in man. Br Heart J (1979) 1.71
The gerB region of the Bacillus subtilis 168 chromosome encodes a homologue of the gerA spore germination operon. Microbiology (1994) 1.65
Effects of mechanical signaling on plant cell cytosolic calcium. Proc Natl Acad Sci U S A (1995) 1.63
Central quadriceps tendon for anterior cruciate ligament reconstruction. Part I: Morphometric and biomechanical evaluation. Am J Sports Med (1997) 1.61
The incidence of osteoporosis in normal women: its relation to age and the menopause. Q J Med (1966) 1.61
Cloning, sequencing, and expression of the apa gene coding for the Mycobacterium tuberculosis 45/47-kilodalton secreted antigen complex. Infect Immun (1995) 1.60
Clinical features of frontotemporal dementia due to the intronic tau 10(+16) mutation. Neurology (2002) 1.60
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]. Science (1985) 1.57
Early identification of children's special needs: a study in five metropolitan communities. J Pediatr (1987) 1.56
Modulated high-energy gamma-ray emission from the microquasar Cygnus X-3. Science (2009) 1.55
The chronicity of symptoms and disability in Reiter's syndrome. An analysis of 131 consecutive patients. Ann Intern Med (1979) 1.53
Site-directed mutagenesis of the 19-kilodalton lipoprotein antigen reveals No essential role for the protein in the growth and virulence of Mycobacterium intracellulare. Infect Immun (1998) 1.53
Severity of illness: concepts and measurements. Lancet (1987) 1.52
Deproteinization with phenol of alternating polydeoxyadenylate-deoxythymidylate and other DNA-like polymers. Anal Biochem (1970) 1.52
Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro. J Mol Biol (2001) 1.51
Treatment of Diamond-Blackfan anaemia with haematopoietic growth factors, granulocyte-macrophage colony stimulating factor and interleukin 3: sustained remissions following IL-3. Br J Haematol (1991) 1.50
Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug. Clin Pharmacol Ther (2008) 1.50
Effects of recombination-deficient and repair-deficient loci on meiotic and mitotic chromosome behavior in Drosophila melanogaster. Basic Life Sci (1980) 1.50
Aetiology and incidence of facial fractures in adults. Int J Oral Surg (1983) 1.49
The use of beta-adrenergic receptor blocking drugs in dysrhythmias. Prog Cardiovasc Dis (1969) 1.47
S-amino acid metabolism and its regulation in Escherichia coli and Salmonella typhimurium. Adv Genet (1971) 1.46
Difference in direct charge-parity violation between charged and neutral B meson decays. Nature (2008) 1.46
The effect of lead poisoning on hematologic and biochemical values in trumpeter swans and Canada geese. Vet Clin Pathol (2007) 1.46
Immunoregulatory T cell abnormalities in mucocutaneous lymph node syndrome. J Immunol (1983) 1.46
Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil. Br J Clin Pharmacol (2001) 1.45
Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies. Neuropathol Appl Neurobiol (2003) 1.44
Mechanisms of granuloma formation in murine Mycobacterium avium infection: the contribution of CD4+ T cells. Int Immunol (1996) 1.44
Heart rate, activity, duration, and affect in added-purpose versus single-purpose jumping activities. Am J Occup Ther (1989) 1.43
Mutants of Salmonella typhimurium responding to cysteine or methionine: their nature and possible role in the regulation of cysteine biosynthesis. J Gen Microbiol (1975) 1.43
Genetic polymorphism of mouse immunoglobulin light chains revealed by isoelectric focusing. J Exp Med (1976) 1.42
The Ortega Hypothesis: Citation analysis suggests that only a few scientists contribute to scientific progress. Science (1972) 1.42
Couples coping with a myocardial infarction: a contextual perspective on wives' distress. J Pers Soc Psychol (1991) 1.42
Going global with osteopathic medicine. J Am Osteopath Assoc (2001) 1.39
The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1. Science (2008) 1.39
Traumatic aneurysms of the internal maxillary artery and their treatment by embolisation: a report of two cases. Br J Oral Maxillofac Surg (1990) 1.39
The use of microsatellite variation to infer population structure and demographic history in a natural model system. Genetics (1999) 1.39
Elephants and man, a big problem. Can Vet J (1989) 1.39
Malfunctioning gas scavenging unit. Anaesthesia (2007) 1.38
Fine mapping of de novo CMT1A and HNPP rearrangements within CMT1A-REPs evidences two distinct sex-dependent mechanisms and candidate sequences involved in recombination. Hum Mol Genet (1998) 1.38
Fermi observations of high-energy gamma-ray emission from GRB 080916C. Science (2009) 1.37
Cyclo-oxygenase (COX) inhibitors for treating preterm labour. Cochrane Database Syst Rev (2005) 1.35
Thermal transitions in mixtures of polydeoxyribodinucleotides. Biopolymers (1970) 1.35
Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile. J Am Coll Cardiol (1999) 1.33
Spatial learning as an adaptation in hummingbirds. Science (1982) 1.33
Granulocyte-macrophage colony stimulating factor exacerbates collagen induced arthritis in mice. Ann Rheum Dis (1997) 1.31