Published in Eur J Clin Pharmacol on May 22, 2003
Prenatal exposure to acetaminophen and respiratory symptoms in the first year of life. Ann Allergy Asthma Immunol (2008) 1.19
Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates. Eur J Clin Pharmacol (2004) 1.04
Safety and population pharmacokinetic analysis of intravenous acetaminophen in neonates, infants, children, and adolescents with pain or Fever. J Pediatr Pharmacol Ther (2011) 0.98
Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr (2011) 0.91
Paracetamol: a focus for the general pediatrician. Eur J Pediatr (2013) 0.87
Prenatal and perinatal analgesic exposure and autism: an ecological link. Environ Health (2013) 0.83
Developmental pharmacokinetics in pediatric populations. J Pediatr Pharmacol Ther (2015) 0.81
Pharmacokinetics of intravenous paracetamol in children and adolescents under major surgery. Eur J Clin Pharmacol (2005) 0.81
Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of concept. Clin Pharmacokinet (2014) 0.80
Clinical pharmacology of paracetamol in neonates: a review. Curr Ther Res Clin Exp (2014) 0.79
Pharmacogenomics of acetaminophen in pediatric populations: a moving target. Front Genet (2014) 0.78
Probable fatal drug interaction between intravenous fenretinide, ceftriaxone, and acetaminophen: a case report from a New Approaches to Neuroblastoma (NANT) Phase I study. BMC Res Notes (2014) 0.77
No urine, no urinary clearance. Eur J Clin Pharmacol (2004) 0.75
Successful Use of [(14)C]Paracetamol Microdosing to Elucidate Developmental Changes in Drug Metabolism. Clin Pharmacokinet (2017) 0.75
A general model for the origin of allometric scaling laws in biology. Science (1997) 24.91
The fourth dimension of life: fractal geometry and allometric scaling of organisms. Science (1999) 10.33
A size standard for pharmacokinetics. Clin Pharmacokinet (1996) 3.44
Acetaminophen elimination kinetics in neonates, children, and adults. Clin Pharmacol Ther (1976) 2.24
A survey of the use of off-label and unlicensed drugs in a Dutch children's hospital. Pediatrics (2001) 2.10
Glucuronidation in humans. Pharmacogenetic and developmental aspects. Clin Pharmacokinet (1999) 1.79
Size, myths and the clinical pharmacokinetics of analgesia in paediatric patients. Clin Pharmacokinet (1997) 1.72
Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion. Pediatrics (1975) 1.52
Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation. Clin Pharmacol Ther (2000) 1.44
A model for size and age changes in the pharmacokinetics of paracetamol in neonates, infants and children. Br J Clin Pharmacol (2000) 1.37
Acetaminophen developmental pharmacokinetics in premature neonates and infants: a pooled population analysis. Anesthesiology (2002) 1.34
The association of age and frailty with paracetamol conjugation in man. Age Ageing (1990) 1.22
Pharmacokinetics of acetaminophen elimination by anephric patients. J Pharmacol Exp Ther (1976) 1.09
Effects of oral contraceptive steroids on acetaminophen metabolism and elimination. Clin Pharmacol Ther (1983) 1.07
The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage. A pharmacokinetic study. Br J Pharmacol (1973) 1.04
Paracetamol metabolism in pregnancy. Br J Clin Pharmacol (1986) 1.01
Series: current issues in mutagenesis and carcinogenesis, No. 65. The genotoxicity and carcinogenicity of paracetamol: a regulatory (re)view. Mutat Res (1996) 1.00
Age-related differences in salicylamide and acetaminophen conjugation in man. J Pediatr (1977) 0.99
Drug use in the neonate: interrelationships of pharmacokinetics, toxicity, and biochemical maturity. Clin Chem (1986) 0.98
Paracetamol metabolites in the neonate following maternal overdose. Br J Clin Pharmacol (1984) 0.95
Acetaminophen poisoning in infancy. Am J Dis Child (1983) 0.94
Comparison of paracetamol metabolism in young adult and elderly males. Eur J Clin Pharmacol (1988) 0.93
Therapeutic doses of codeine have no effect on acetaminophen clearance or metabolism. Eur J Clin Pharmacol (1988) 0.92
Pharmacokinetics and metabolism of rectally administered paracetamol in preterm neonates. Arch Dis Child Fetal Neonatal Ed (1999) 0.91
Selective inhibition of acetaminophen oxidation and toxicity by cimetidine and other histamine H2-receptor antagonists in vivo and in vitro in the rat and in man. J Clin Invest (1984) 0.89
Determinants of acetaminophen metabolism: effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways. Clin Pharmacol Ther (1984) 0.87
Assay of paracetamol and its metabolites in urine, plasma and saliva of children with chronic liver disease. J Pharm Biomed Anal (1995) 0.86
Analgesic efficacy of rectal versus oral acetaminophen in children after major craniofacial surgery. Clin Pharmacol Ther (2001) 0.85
Paracetamol elimination in patients with non-insulin dependent diabetes mellitus. Br J Clin Pharmacol (1993) 0.83
Circadian rhythm of serum sulfate levels in man and acetaminophen pharmacokinetics. Eur J Clin Pharmacol (1990) 0.81
Effects of posture and sleep on the pharmacokinetics of paracetamol (acetaminophen) and its metabolites. Clin Pharmacokinet (1991) 0.80
Effect of vasopressin on the reabsorption of phenacetin and its metabolites from the tubular fluid in man. Clin Sci (1972) 0.79
Paracetamol metabolism in patients with ulcerative colitis. Br J Clin Pharmacol (1998) 0.78
Glomerular filtration rate, effective renal blood flow, and maximal tubular excretory capacity in infancy. J Pediatr (1948) 0.78
Paracetamol disposition in Thai patients during and after treatment of falciparum malaria. Eur J Clin Pharmacol (1995) 0.77
Perturbation of paracetamol urinary metabolic ratios by urine flow rate. Br J Clin Pharmacol (1992) 0.77
The effect of propranolol on paracetamol metabolism in man. Br J Clin Pharmacol (1990) 0.75
Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates. Arch Pediatr Adolesc Med (2003) 2.94
Unlicensed and off label prescription of drugs to children: population based cohort study. BMJ (2002) 2.34
Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev Biol (2008) 2.06
Prematurity, Opioid Exposure and Neonatal Pain: Do They Affect the Developing Brain? Neonatology (2015) 1.96
Human renal function maturation: a quantitative description using weight and postmenstrual age. Pediatr Nephrol (2008) 1.88
Persistent low microcirculatory vessel density in nonsurvivors of sepsis in pediatric intensive care. Crit Care Med (2011) 1.87
The use of the Behavioral Pain Scale to assess pain in conscious sedated patients. Anesth Analg (2009) 1.79
Population clinical pharmacology of children: modelling covariate effects. Eur J Pediatr (2006) 1.79
Which aspects of safety culture predict incident reporting behavior in neonatal intensive care units? A multilevel analysis. Crit Care Med (2009) 1.78
Guidelines on paediatric dosing on the basis of developmental physiology and pharmacokinetic considerations. Clin Pharmacokinet (2006) 1.78
Assessment of sedation levels in pediatric intensive care patients can be improved by using the COMFORT "behavior" scale. Pediatr Crit Care Med (2005) 1.76
Withdrawal symptoms in critically ill children after long-term administration of sedatives and/or analgesics: a first evaluation. Crit Care Med (2008) 1.74
The pharmacokinetics of intravenous paracetamol in neonates: size matters most. Arch Dis Child (2011) 1.71
Dysphagia in children with severe generalized cerebral palsy and intellectual disability. Dev Med Child Neurol (2008) 1.70
Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am J Physiol Lung Cell Mol Physiol (2007) 1.68
Routine morphine infusion in preterm newborns who received ventilatory support: a randomized controlled trial. JAMA (2003) 1.66
Evidence for water ice near Mercury's north pole from MESSENGER Neutron Spectrometer measurements. Science (2012) 1.62
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. Nat Genet (2012) 1.61
Changes in buccal microcirculation following extracorporeal membrane oxygenation in term neonates with severe respiratory failure. Crit Care Med (2009) 1.59
Chromosomal anomalies in the aetiology of oesophageal atresia and tracheo-oesophageal fistula. Eur J Med Genet (2007) 1.55
Population clinical pharmacology of children: general principles. Eur J Pediatr (2006) 1.54
CYP3A5 variant allele frequencies in Dutch Caucasians. Clin Chem (2002) 1.53
Long-term neuropsychological outcomes in children and adolescents after cardiac arrest. Intensive Care Med (2015) 1.51
Adequate feeding and the usefulness of the respiratory quotient in critically ill children. Nutrition (2005) 1.51
Pain relief in ventilated preterms during endotracheal suctioning: a randomized controlled trial. Swiss Med Wkly (2008) 1.51
The SLCO1B1 rs4149032 polymorphism is highly prevalent in South Africans and is associated with reduced rifampin concentrations: dosing implications. Antimicrob Agents Chemother (2011) 1.49
Analgesia-sedation in PICU and neurological outcome: a secondary analysis of long-term neuropsychological follow-up in meningococcal septic shock survivors*. Pediatr Crit Care Med (2014) 1.49
Vancomycin pharmacokinetics in preterm neonates and the prediction of adult clearance. Br J Clin Pharmacol (2006) 1.49
Steam inhalation therapy: severe scalds as an adverse side effect. Br J Gen Pract (2012) 1.48
Illness severity and parental permission for clinical research in a pediatric ICU population. Intensive Care Med (2005) 1.48
The effect of critical illness and inflammation on midazolam therapy in children. Pediatr Crit Care Med (2012) 1.48
Homozygous nonsense mutations in KIAA1279 are associated with malformations of the central and enteric nervous systems. Am J Hum Genet (2005) 1.47
Individualized dosing of aminoglycosides in neonates: mission accomplished or work in progress? Eur J Clin Pharmacol (2009) 1.46
Medication errors--new approaches to prevention. Paediatr Anaesth (2011) 1.44
Environmental factors in the etiology of esophageal atresia and congenital diaphragmatic hernia: results of a case-control study. Birth Defects Res A Clin Mol Teratol (2008) 1.43
Dyskinesia and the antiparkinsonian response always temporally coincide: a retrospective study. Neurology (2010) 1.43
Cisapride: a potential model substrate to assess cytochrome P4503A4 activity in vivo. Clin Pharmacol Ther (2003) 1.42
Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development. PLoS One (2013) 1.42
Evaluation of drug formularies for pediatric intensive care. Pediatr Crit Care Med (2011) 1.42
Awareness in children: another two cases. Paediatr Anaesth (2008) 1.42
Surfactant phosphatidylcholine pool size in human neonates with congenital diaphragmatic hernia requiring ECMO. J Pediatr (2003) 1.41
Information technology cannot guarantee patient safety. BMJ (2007) 1.41
Extended-interval dosing of tobramycin in neonates: implications for therapeutic drug monitoring. Clin Pharmacol Ther (2002) 1.41
Vancomycin: pharmacokinetics and administration regimens in neonates. Clin Pharmacokinet (2004) 1.40
Inter- and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the F factor relaxase. Structure (2005) 1.40
The COMFORT behavior scale: is a shorter observation period feasible?. Pediatr Crit Care Med (2012) 1.40
Prospective longitudinal evaluation of lung function during the first year of life after extracorporeal membrane oxygenation. Pediatr Crit Care Med (2011) 1.40
Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care (2006) 1.40
Progression of motor and nonmotor features of Parkinson's disease and their response to treatment. Br J Clin Pharmacol (2012) 1.39
Is pain assessment feasible as a performance indicator for Dutch nursing homes? A cross-sectional approach. Pain Manag Nurs (2010) 1.39
MESSENGER observations of magnetic reconnection in Mercury's magnetosphere. Science (2009) 1.39
A Comparative Analysis of Preemptive Versus Targeted Sedation on Cardiovascular Stability After High-Risk Cardiac Surgery in Infants. Pediatr Crit Care Med (2016) 1.38
Routine enteral nutrition in neonates on extracorporeal membrane oxygenation. Pediatr Crit Care Med (2005) 1.38
Growing Up After Critical Illness: Verbal, Visual-Spatial, and Working Memory Problems in Neonatal Extracorporeal Membrane Oxygenation Survivors. Crit Care Med (2016) 1.38
Limited predictability of amikacin clearance in extreme premature neonates at birth. Br J Clin Pharmacol (2006) 1.37
The pharmacokinetics and safety of micafungin, a novel echinocandin, in premature infants. Pediatr Infect Dis J (2006) 1.36
Non-VACTERL-type anomalies are frequent in patients with esophageal atresia/tracheo-esophageal fistula and full or partial VACTERL association. Birth Defects Res A Clin Mol Teratol (2008) 1.36
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years. Clin Pharmacokinet (2009) 1.34
Acetaminophen developmental pharmacokinetics in premature neonates and infants: a pooled population analysis. Anesthesiology (2002) 1.34
Thoracoscopic repair in congenital diaphragmatic hernia: patching is safe and reduces the recurrence rate. J Pediatr Surg (2010) 1.31
Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am J Physiol Lung Cell Mol Physiol (2004) 1.29
Distal angiogenesis: a new concept for lung vascular morphogenesis. Am J Physiol Lung Cell Mol Physiol (2004) 1.28
Renal drug clearance in preterm neonates: relation to prenatal growth. Ther Drug Monit (2007) 1.28
Does neonatal surgery lead to increased pain sensitivity in later childhood? Pain (2005) 1.27
Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder. Genome Res (2012) 1.26
Postoperative pain in the neonate: age-related differences in morphine requirements and metabolism. Intensive Care Med (2003) 1.25
Defect size determines survival in infants with congenital diaphragmatic hernia. Pediatrics (2007) 1.25
Genome-wide oligonucleotide-based array comparative genome hybridization analysis of non-isolated congenital diaphragmatic hernia. Hum Mol Genet (2007) 1.24
Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study. Intensive Care Med (2013) 1.23
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
Analysis of population pharmacokinetic data using NONMEM and WinBUGS. J Biopharm Stat (2005) 1.18
MESSENGER observations of transient bursts of energetic electrons in Mercury's magnetosphere. Science (2011) 1.17
Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's disease. Br J Clin Pharmacol (2012) 1.17
Population pharmacokinetics of midazolam and its metabolites during venoarterial extracorporeal membrane oxygenation in neonates. Clin Pharmacokinet (2010) 1.17
Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation. Neonatology (2009) 1.16
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. J Clin Endocrinol Metab (2002) 1.16
The efficacy of non-pharmacological interventions in the management of procedural pain in preterm and term neonates. A systematic literature review. Eur J Pain (2006) 1.15
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn (2008) 1.15
Alveolar capillary dysplasia: a logical approach to a fatal disease. J Pediatr Surg (2005) 1.15
Evaluation of pharmacist clinical interventions in a Dutch hospital setting. Pharm World Sci (2007) 1.13
Comparison of different pain scoring systems in critically ill patients in a general ICU. Crit Care (2008) 1.12
Evaluation of furosemide regimens in neonates treated with extracorporeal membrane oxygenation. Crit Care (2006) 1.12
Educational paper: do we need neonatal clinical pharmacologists? Eur J Pediatr (2012) 1.12
Acute kidney injury is a frequent complication in critically ill neonates receiving extracorporeal membrane oxygenation: a 14-year cohort study. Crit Care (2013) 1.11
Standardized reporting for congenital diaphragmatic hernia--an international consensus. J Pediatr Surg (2013) 1.11
Malnutrition in critically ill children: from admission to 6 months after discharge. Clin Nutr (2004) 1.10
The effect of cumulative energy and protein deficiency on anthropometric parameters in a pediatric ICU population. Clin Nutr (2004) 1.10
Dexmedetomidine pharmacokinetics in pediatric intensive care--a pooled analysis. Paediatr Anaesth (2009) 1.10
Impact of obesity on drug metabolism and elimination in adults and children. Clin Pharmacokinet (2012) 1.10
Population pharmacokinetic and adverse event analysis of topotecan in patients with solid tumors. Clin Pharmacol Ther (2002) 1.10