Published in J Cell Biochem on June 01, 2003
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell (2007) 5.87
Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place? Carcinogenesis (2010) 0.97
Novel molecular, cytotoxical, and immunological study on promising and selective anticancer activity of mung bean sprouts. BMC Complement Altern Med (2012) 0.87
Anti-tumor action of tumor necrosis factor against Bomirski Ab melanoma in hamsters. Arch Immunol Ther Exp (Warsz) (2007) 0.75
Glycolytic enzymes can modulate cellular life span. Cancer Res (2005) 3.78
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Curr Cancer Drug Targets (2008) 3.36
PTEN, more than the AKT pathway. Carcinogenesis (2007) 2.70
High content screening: seeing is believing. Trends Biotechnol (2010) 2.63
Roscovitine targets, protein kinases and pyridoxal kinase. J Biol Chem (2005) 2.31
Inhibition of HSP90 molecular chaperones: moving into the clinic. Lancet Oncol (2013) 1.84
CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus. Oncogene (2005) 1.63
Spinophilin acts as a tumor suppressor by regulating Rb phosphorylation. Cell Cycle (2011) 1.53
Spinophilin loss contributes to tumorigenesis in vivo. Cell Cycle (2011) 1.45
Protein localization in disease and therapy. J Cell Sci (2011) 1.42
Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients. Mol Cancer Ther (2005) 1.32
Pim kinases in cancer: diagnostic, prognostic and treatment opportunities. Biochem Pharmacol (2012) 1.31
Immortalization of primary human prostate epithelial cells by c-Myc. Cancer Res (2005) 1.30
Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation. Mol Cell Biol (2009) 1.20
The PIM family of serine/threonine kinases in cancer. Med Res Rev (2013) 1.17
Cell cycle deregulation: a common motif in cancer. Prog Cell Cycle Res (2003) 1.14
Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt. J Cell Biochem (2005) 1.04
Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer. Carcinogenesis (2006) 1.03
Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases. J Biol Chem (2009) 1.03
Understanding FOXO, new views on old transcription factors. Curr Cancer Drug Targets (2010) 1.01
Activation of phosphatidylinositol 3-kinase by membrane localization of p110alpha predisposes mammary glands to neoplastic transformation. Cancer Res (2008) 0.97
Genetic diversity in recent elite faba bean lines using AFLP markers. Theor Appl Genet (2003) 0.97
Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening. Chembiochem (2008) 0.97
Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity. Cancer Res (2005) 0.96
An HTS approach to screen for antagonists of the nuclear export machinery using high content cell-based assays. Assay Drug Dev Technol (2007) 0.95
Components and regulation of nuclear transport processes. FEBS J (2014) 0.94
Mitotic catastrophe cell death induced by heat shock protein 90 inhibitor in BRCA1-deficient breast cancer cell lines. Mol Cancer Ther (2008) 0.94
A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery. Cytometry A (2010) 0.94
Levels of p27(kip1) determine Aplidin sensitivity. Mol Cancer Ther (2007) 0.94
MAP17 enhances the malignant behavior of tumor cells through ROS increase. Carcinogenesis (2007) 0.93
Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition. Cancer Lett (2010) 0.93
PPP1CA contributes to the senescence program induced by oncogenic Ras. Carcinogenesis (2008) 0.92
DNA methylation signatures identify biologically distinct thyroid cancer subtypes. J Clin Endocrinol Metab (2013) 0.92
MAP17 overexpression is a common characteristic of carcinomas. Carcinogenesis (2007) 0.92
Extreme sensitivity to Yondelis (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53. J Cell Biochem (2007) 0.91
Association between the miRNA signatures in plasma and bronchoalveolar fluid in respiratory pathologies. Dis Markers (2012) 0.90
Down-regulation of spinophilin in lung tumours contributes to tumourigenesis. J Pathol (2011) 0.89
Targeting nucleocytoplasmic transport in cancer therapy. Oncotarget (2014) 0.88
Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models. PLoS One (2010) 0.87
Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas. Blood (2007) 0.87
Loss-of-function genetic screening identifies a cluster of ribosomal proteins regulating p53 function. Carcinogenesis (2008) 0.87
MAP17 and SGLT1 protein expression levels as prognostic markers for cervical tumor patient survival. PLoS One (2013) 0.86
Characterization of the p53 response to oncogene-induced senescence. PLoS One (2008) 0.86
The essential role of PIM kinases in sarcoma growth and bone invasion. Carcinogenesis (2012) 0.86
Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators. BMC Cell Biol (2009) 0.86
Spinophilin loss correlates with poor patient prognosis in advanced stages of colon carcinoma. Clin Cancer Res (2013) 0.86
Imaged-based high-throughput screening for anti-angiogenic drug discovery. Curr Pharm Des (2010) 0.86
The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras. Carcinogenesis (2010) 0.86
Cellular senescence induced by p53-ras cooperation is independent of p21waf1 in murine embryo fibroblasts. J Cell Biochem (2004) 0.86
MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation. Carcinogenesis (2007) 0.86
Cellular senescence as a target in cancer control. J Aging Res (2010) 0.85
Genetic modelling of the PTEN/AKT pathway in cancer research. Clin Transl Oncol (2008) 0.85
Mouse models to decipher the PI3K signaling network in human cancer. Curr Mol Med (2009) 0.84
Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes. Dalton Trans (2009) 0.84
Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria. Anticancer Drugs (2005) 0.84
The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity. Dalton Trans (2010) 0.83
Moving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation. Traffic (2013) 0.83
A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling. PLoS One (2008) 0.83
Identification of oxidative stress related proteins as biomarkers for lung cancer and chronic obstructive pulmonary disease in bronchoalveolar lavage. Int J Mol Sci (2013) 0.82
Inhibiting PI3K as a therapeutic strategy against cancer. Clin Transl Oncol (2009) 0.82
PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome. BMC Cancer (2012) 0.81
Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR. Bioorg Med Chem Lett (2012) 0.81
Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues. Mol Ther (2009) 0.81
Quantitative genetic analysis of embryo heterosis in faba bean (Vicia faba L.). Theor Appl Genet (2010) 0.80
The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine. Eur J Med Chem (2009) 0.80
Using cells devoid of RAS proteins as tools for drug discovery. Mol Carcinog (2009) 0.79
Hybrid embryos of Vicia faba develop enhanced sink strength, which is established during early development. Plant J (2011) 0.79
Structure-activity relationship of new trans-platinum(II) and (IV) complexes with cyclohexylamine. Interference with cell cycle progression and induction of cell death. J Inorg Biochem (2006) 0.79
Bypassing cellular senescence by genetic screening tools. Clin Transl Oncol (2010) 0.78
A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation. Metallomics (2014) 0.78
Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693. ChemMedChem (2014) 0.78
The therapeutic potential of FOXO proteins. Curr Drug Targets (2011) 0.78
Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor. Bioorg Med Chem Lett (2012) 0.78
Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia. PLoS One (2013) 0.78
Image-based high-throughput screening for inhibitors of angiogenesis. Methods Mol Biol (2013) 0.78
Imidazo[1,2-a]pyrazines as novel PI3K inhibitors. Bioorg Med Chem Lett (2012) 0.77
An integrated one-step system to extract, analyze and annotate all relevant information from image-based cell screening of chemical libraries. Mol Biosyst (2010) 0.77
Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate. Carcinogenesis (2007) 0.77
New trans-platinum drugs with phosphines and amines as carrier ligands induce apoptosis in tumor cells resistant to cisplatin. J Med Chem (2007) 0.77
Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases. Invest New Drugs (2012) 0.77
MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer. BMC Cancer (2014) 0.77
High-content screening of natural products reveals novel nuclear export inhibitors. J Biomol Screen (2013) 0.76
Context-dependent therapeutic potential of FOXO proteins in oral squamous cell carcinoma. Oral Oncol (2011) 0.76
EMX homeobox genes regulate microphthalmia and alter melanocyte biology. Exp Cell Res (2005) 0.76
Special Review: Caught in the Crosshairs: Targeted Drugs and Personalized Medicine. Cancer J (2015) 0.76
Cancer, senescence, and aging: translation from basic research to clinics. J Aging Res (2011) 0.76
Battling cancer on many fronts. Meeting on New Battlefields in Human Cancer--Attacking in Many Fronts. EMBO Rep (2008) 0.75
Meeting report: trends and challenges in high content analysis. Biotechnol J (2007) 0.75
Oxidation of anticancer Pt(II) complexes with monodentate phosphane ligands: towards stable but active Pt(IV) prodrugs. Chem Commun (Camb) (2013) 0.75
Influence of (hydroxymethyl)pyridine and pyridine-carboxylic acids, in trans-position to the isopropylamine and amine ligands, on the cytotoxicity of platinum complexes. Chem Biodivers (2008) 0.75
Image-based identification of nuclear export inhibitors from natural products. Methods Mol Biol (2015) 0.75
Identification of transcripts specific for physiological gene activation by platelet-derived growth factor (PDGF)-B in intact brain tissue. J Cell Biochem (2005) 0.75
The second generation of iodido complexes: trans-[PtI2(amine)(amine')] bearing different aliphatic amines. J Inorg Biochem (2013) 0.75