Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial.
|
J Natl Cancer Inst
|
2003
|
3.41
|
2
|
First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: the TORCH randomized trial.
|
J Clin Oncol
|
2012
|
3.04
|
3
|
Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the elderly study.
|
J Clin Oncol
|
2005
|
2.11
|
4
|
NF-kappaB and virus infection: who controls whom.
|
EMBO J
|
2003
|
2.08
|
5
|
Unanswered questions: monoclonal antibodies in the treatment of advanced non-small-cell lung cancer.
|
Oncology (Williston Park)
|
2010
|
2.06
|
6
|
Compliance with therapy in hypertensive patients.
|
Intern Emerg Med
|
2006
|
1.66
|
7
|
Factorial phase III randomised trial of rofecoxib and prolonged constant infusion of gemcitabine in advanced non-small-cell lung cancer: the GEmcitabine-COxib in NSCLC (GECO) study.
|
Lancet Oncol
|
2007
|
1.60
|
8
|
Transcription of Satellite III non-coding RNAs is a general stress response in human cells.
|
Nucleic Acids Res
|
2007
|
1.58
|
9
|
Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.
|
MBio
|
2012
|
1.55
|
10
|
Treating advanced non-small cell lung cancer in the elderly.
|
Ther Adv Med Oncol
|
2010
|
1.53
|
11
|
A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype.
|
Hum Mol Genet
|
2005
|
1.43
|
12
|
The potential role of mTOR inhibitors in non-small cell lung cancer.
|
Oncologist
|
2008
|
1.39
|
13
|
Treatment of pulmonary neuroendocrine tumours: state of the art and future developments.
|
Cancer Treat Rev
|
2012
|
1.37
|
14
|
Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis.
|
J Biol Chem
|
2006
|
1.33
|
15
|
Treatment of advanced non small cell lung cancer.
|
J Thorac Dis
|
2011
|
1.32
|
16
|
Proinflammatory cytokines and cardiac abnormalities in uncomplicated obesity: relationship with abdominal fat deposition.
|
Nutr Metab Cardiovasc Dis
|
2006
|
1.27
|
17
|
Systemic inflammatory status at baseline predicts bevacizumab benefit in advanced non-small cell lung cancer patients.
|
Cancer Biol Ther
|
2013
|
1.26
|
18
|
Erlotinib in non-small cell lung cancer treatment: current status and future development.
|
Oncologist
|
2007
|
1.26
|
19
|
Dermatophytes: host-pathogen interaction and antifungal resistance.
|
An Bras Dermatol
|
2010
|
1.23
|
20
|
Herpes simplex virus disrupts NF-kappaB regulation by blocking its recruitment on the IkappaBalpha promoter and directing the factor on viral genes.
|
J Biol Chem
|
2006
|
1.22
|
21
|
The role of bevacizumab in the treatment of non-small cell lung cancer: current indications and future developments.
|
Oncologist
|
2007
|
1.20
|
22
|
Heparin strongly enhances the formation of beta2-microglobulin amyloid fibrils in the presence of type I collagen.
|
J Biol Chem
|
2007
|
1.18
|
23
|
Phenotypic features of carbohydrate sulfotransferase 3 (CHST3) deficiency in 24 patients: congenital dislocations and vertebral changes as principal diagnostic features.
|
Am J Med Genet A
|
2010
|
1.17
|
24
|
Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis.
|
Am J Hum Genet
|
2008
|
1.15
|
25
|
Sorafenib and sunitinib in the treatment of advanced non-small cell lung cancer.
|
Oncologist
|
2007
|
1.14
|
26
|
Chondrodysplasia and abnormal joint development associated with mutations in IMPAD1, encoding the Golgi-resident nucleotide phosphatase, gPAPP.
|
Am J Hum Genet
|
2011
|
1.12
|
27
|
Antifungal resistance mechanisms in dermatophytes.
|
Mycopathologia
|
2008
|
1.10
|
28
|
Risk/benefit profile of bevacizumab in metastatic colon cancer: a systematic review and meta-analysis.
|
Dig Liver Dis
|
2010
|
1.09
|
29
|
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta.
|
Blood
|
2009
|
1.08
|
30
|
Three cases of long-lasting tumor control with erlotinib after progression with gefitinib in advanced non-small cell lung cancer.
|
J Thorac Oncol
|
2007
|
1.07
|
31
|
Treatment of advanced non-small-cell lung cancer in the elderly.
|
Lung Cancer
|
2009
|
1.07
|
32
|
Treatment of non-small-cell lung cancer: state of the art and development of new biologic agents.
|
Oncogene
|
2003
|
1.06
|
33
|
Vascular disrupting agents: a novel mechanism of action in the battle against non-small cell lung cancer.
|
Oncologist
|
2009
|
1.05
|
34
|
Supportive care in patients with advanced non-small-cell lung cancer.
|
Br J Cancer
|
2003
|
1.04
|
35
|
Outcomes of small-cell lung cancer patients treated with second-line chemotherapy: a multi-institutional retrospective analysis.
|
Lung Cancer
|
2010
|
1.03
|
36
|
ALK inhibitors: a new targeted therapy in the treatment of advanced NSCLC.
|
Target Oncol
|
2013
|
1.02
|
37
|
Differential expression of both extracellular and intracellular proteins is involved in the lethal or nonlethal phenotypic variation of BrtlIV, a murine model for osteogenesis imperfecta.
|
Proteomics
|
2007
|
1.01
|
38
|
Interaction of decorin with CNBr peptides from collagens I and II. Evidence for multiple binding sites and essential lysyl residues in collagen.
|
Eur J Biochem
|
2002
|
1.01
|
39
|
Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy.
|
Stem Cells
|
2012
|
1.00
|
40
|
Lung cancer in the elderly.
|
J Clin Oncol
|
2007
|
1.00
|
41
|
Molecular diagnosis of analbuminemia: a novel mutation identified in two Amerindian and two Turkish families.
|
Clin Chem
|
2002
|
0.99
|
42
|
Potential treatment options after first-line chemotherapy for advanced NSCLC: maintenance treatment or early second-line?
|
Oncologist
|
2009
|
0.99
|
43
|
Vaccines for the treatment of non-small cell lung cancer: a renewed anticancer strategy.
|
Oncologist
|
2009
|
0.97
|
44
|
The potential role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer.
|
Crit Rev Oncol Hematol
|
2008
|
0.96
|
45
|
The pH signaling transcription factor PacC mediates the growth of Trichophyton rubrum on human nail in vitro.
|
Med Mycol
|
2006
|
0.94
|
46
|
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen.
|
Protein Sci
|
2005
|
0.94
|
47
|
Medical treatment of small cell lung cancer: state of the art and new development.
|
Expert Opin Pharmacother
|
2013
|
0.94
|
48
|
Single-agent pemetrexed or sequential pemetrexed/gemcitabine as front-line treatment of advanced non-small cell lung cancer in elderly patients or patients ineligible for platinum-based chemotherapy: a multicenter, randomized, phase II trial.
|
J Thorac Oncol
|
2007
|
0.93
|
49
|
Defective proteoglycan sulfation of the growth plate zones causes reduced chondrocyte proliferation via an altered Indian hedgehog signalling.
|
Matrix Biol
|
2010
|
0.92
|
50
|
Randomized phase IIIb trial evaluating the continuation of bevacizumab beyond disease progression in patients with advanced non-squamous non-small-cell lung cancer after first-line treatment with bevacizumab plus platinum-based chemotherapy: treatment rationale and protocol dynamics of the AvaALL (MO22097) trial.
|
Clin Lung Cancer
|
2011
|
0.91
|
51
|
A novel splicing mutation causes an undescribed type of analbuminemia.
|
Biochim Biophys Acta
|
2002
|
0.90
|
52
|
Biological and clinical features in predicting efficacy of epidermal growth factor receptor tyrosine kinase inhibitors: a systematic review and meta-analysis.
|
Anticancer Res
|
2009
|
0.90
|
53
|
Tumor-related leucocytosis and chemotherapy-induced neutropenia: linked or independent prognostic factors for advanced non-small cell lung cancer?
|
Lung Cancer
|
2009
|
0.90
|
54
|
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
|
Hum Mutat
|
2012
|
0.89
|
55
|
A transcript finishing initiative for closing gaps in the human transcriptome.
|
Genome Res
|
2004
|
0.89
|
56
|
Cetuximab and gemcitabine in elderly or adult PS2 patients with advanced non-small-cell lung cancer: The cetuximab in advanced lung cancer (CALC1-E and CALC1-PS2) randomized phase II trials.
|
Lung Cancer
|
2010
|
0.88
|
57
|
Self-aggregation of fibrillar collagens I and II involves lysine side chains.
|
Micron
|
2006
|
0.88
|
58
|
EURTAC first-line phase III randomized study in advanced non-small cell lung cancer: Erlotinib works also in European population.
|
J Thorac Dis
|
2012
|
0.88
|
59
|
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship.
|
J Hum Genet
|
2004
|
0.88
|
60
|
The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non-small cell lung cancer.
|
Expert Opin Investig Drugs
|
2010
|
0.88
|
61
|
Erlotinib in the treatment of non-small cell lung cancer: current status and future developments.
|
Anticancer Res
|
2010
|
0.88
|
62
|
Trastuzumab cardiotoxicity: biological hypotheses and clinical open issues.
|
Expert Opin Biol Ther
|
2008
|
0.88
|
63
|
Management of unfit older patients with advanced NSCLC.
|
Cancer Treat Rev
|
2009
|
0.87
|
64
|
A "live" biopsy in a small-cell lung cancer patient by detection of circulating tumor cells.
|
Lung Cancer
|
2009
|
0.87
|
65
|
Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum.
|
BMC Microbiol
|
2010
|
0.87
|
66
|
A randomized phase II study of sorafenib/gemcitabine or sorafenib/erlotinib for advanced non-small-cell lung cancer in elderly patients or patients with a performance status of 2: treatment rationale and protocol dynamics.
|
Clin Lung Cancer
|
2007
|
0.87
|
67
|
Advances in chemotherapy in advanced non-small-cell lung cancer.
|
Expert Opin Pharmacother
|
2010
|
0.87
|
68
|
Role of pH in the pathogenesis of dermatophytoses.
|
Mycoses
|
2011
|
0.86
|
69
|
Cetuximab and other anti-epidermal growth factor receptor monoclonal antibodies in the treatment of non-small cell lung cancer.
|
Oncologist
|
2009
|
0.86
|
70
|
New molecular targets in the treatment of NSCLC.
|
Curr Pharm Des
|
2013
|
0.86
|
71
|
Pemetrexed in advanced non-small cell lung cancer.
|
Expert Opin Drug Saf
|
2011
|
0.85
|
72
|
N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
|
Biochim Biophys Acta
|
2005
|
0.85
|
73
|
A splice variant of the Neurospora crassa hex-1 transcript, which encodes the major protein of the Woronin body, is modulated by extracellular phosphate and pH changes.
|
FEBS Lett
|
2008
|
0.85
|
74
|
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage.
|
Proteomics
|
2007
|
0.84
|
75
|
Transcriptional profiling reveals genes in the human pathogen Trichophyton rubrum that are expressed in response to pH signaling.
|
Microb Pathog
|
2009
|
0.84
|
76
|
Physiological performance of a detergent decellularized heart valve implanted for 15 months in Vietnamese pigs: surgical procedure, follow-up, and explant inspection.
|
Artif Organs
|
2012
|
0.84
|
77
|
Anti PD-1 and PDL-1 Immunotherapy in the Treatment of Advanced Non- Small Cell Lung Cancer (NSCLC): A Review on Toxicity Profile and its Management.
|
Curr Drug Saf
|
2016
|
0.83
|
78
|
New avenues for second-line treatment of metastatic non-small-cell lung cancer.
|
Expert Rev Anticancer Ther
|
2009
|
0.83
|
79
|
A multicenter randomized phase IIb efficacy study of Vx-001, a peptide-based cancer vaccine as maintenance treatment in advanced non-small-cell lung cancer: treatment rationale and protocol dynamics.
|
Clin Lung Cancer
|
2013
|
0.83
|
80
|
First-line chemotherapy with fluorouracil and folinic acid for advanced colorectal cancer in elderly patients: a phase II study.
|
J Clin Gastroenterol
|
2003
|
0.83
|
81
|
A randomized phase II study of pemetrexed or RAD001 as second-line treatment of advanced non-small-cell lung cancer in elderly patients: treatment rationale and protocol dynamics.
|
Clin Lung Cancer
|
2007
|
0.83
|
82
|
Alteration of proteoglycan sulfation affects bone growth and remodeling.
|
Bone
|
2013
|
0.83
|
83
|
Prognostic impact of education level of patients with advanced non-small cell lung cancer enrolled in clinical trials.
|
Lung Cancer
|
2012
|
0.83
|
84
|
Matrix disruptions, growth, and degradation of cartilage with impaired sulfation.
|
J Biol Chem
|
2012
|
0.82
|
85
|
Raltitrexed and mitomycin-C as third-line chemotherapy for colorectal cancer after combination regimens including 5-fluorouracil, irinotecan and oxaliplatin: a phase II study.
|
Anticancer Res
|
2003
|
0.82
|
86
|
The emerging role of ALK inhibitors in the treatment of advanced non-small cell lung cancer.
|
Expert Opin Ther Targets
|
2012
|
0.82
|
87
|
Subcutaneous angioleiomyoma of the nasal tip. Report of a rare case.
|
In Vivo
|
2012
|
0.82
|
88
|
Treatment of advanced non-small-cell lung cancer: Italian Association of Thoracic Oncology (AIOT) clinical practice guidelines.
|
Lung Cancer
|
2011
|
0.82
|
89
|
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
|
FEBS J
|
2006
|
0.82
|
90
|
The potential role of bevacizumab in early stages and locally advanced non-small cell lung cancer.
|
Ther Adv Med Oncol
|
2009
|
0.81
|
91
|
Differential response to intracellular stress in the skin from osteogenesis imperfecta Brtl mice with lethal and non lethal phenotype: a proteomic approach.
|
J Proteomics
|
2012
|
0.81
|
92
|
Neutrophil granulocytes uniquely express, among human blood cells, high levels of Methionine-sulfoxide-reductase enzymes.
|
J Leukoc Biol
|
2007
|
0.81
|
93
|
2010 Consensus on Lung Cancer, new clinical recommendations and current status of biomarker assessment--first-line therapy.
|
Eur J Cancer
|
2011
|
0.81
|
94
|
Adjuvant chemotherapy in elderly patients with non-small-cell lung cancer.
|
Cancer Control
|
2007
|
0.81
|
95
|
Erlotinib in non-small-cell lung cancer.
|
Expert Opin Pharmacother
|
2007
|
0.81
|
96
|
Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.
|
Cell Stress Chaperones
|
2011
|
0.81
|
97
|
Factors driving the choice of the best second-line treatment of advanced NSCLC.
|
Rev Recent Clin Trials
|
2011
|
0.81
|
98
|
rpb2 is a reliable reference gene for quantitative gene expression analysis in the dermatophyte Trichophyton rubrum.
|
Med Mycol
|
2011
|
0.81
|
99
|
Transcription of the Neurospora crassa 70-kDa class heat shock protein genes is modulated in response to extracellular pH changes.
|
Cell Stress Chaperones
|
2009
|
0.81
|
100
|
Identification of genes displaying differential expression in the nuc-2 mutant strain of the mold Neurospora crassa grown under phosphate starvation.
|
FEMS Microbiol Lett
|
2007
|
0.81
|
101
|
Identification of genes differentially expressed in a strain of the mold Aspergillus nidulans carrying a loss-of-function mutation in the palA gene.
|
Can J Microbiol
|
2008
|
0.80
|
102
|
A phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in pretreated patients with small-cell lung cancer.
|
J Thorac Oncol
|
2013
|
0.80
|
103
|
Plasma volume and hematocrit changes in recurrent fainters.
|
Clin Auton Res
|
2003
|
0.80
|
104
|
Combined chemo-radiotherapy for locally advanced non-small cell lung cancer: current status and future development.
|
Crit Rev Oncol Hematol
|
2008
|
0.80
|
105
|
The c-Met inhibitors: a new class of drugs in the battle against advanced nonsmall-cell lung cancer.
|
Curr Pharm Des
|
2012
|
0.80
|
106
|
A Mn(II)-Mn(II) center in human prolidase.
|
Biochim Biophys Acta
|
2012
|
0.79
|
107
|
Novel nonsense mutation causes analbuminemia in a Moroccan family.
|
Clin Chem
|
2005
|
0.79
|
108
|
Partial Rescue of Biochemical Parameters After Hematopoietic Stem Cell Transplantation in a Patient with Prolidase Deficiency Due to Two Novel PEPD Mutations.
|
JIMD Rep
|
2011
|
0.79
|
109
|
Transcriptional changes in the nuc-2A mutant strain of Neurospora crassa cultivated under conditions of phosphate shortage.
|
Microbiol Res
|
2009
|
0.79
|
110
|
Postural hypotension in hypertensive patients.
|
Blood Press
|
2003
|
0.79
|
111
|
Potential role of molecularly targeted therapy in the management of advanced nonsmall cell lung carcinoma in the elderly.
|
Cancer
|
2004
|
0.79
|
112
|
Transcriptional profiling of Neurospora crassa Δmak-2 reveals that mitogen-activated protein kinase MAK-2 participates in the phosphate signaling pathway.
|
Fungal Genet Biol
|
2013
|
0.78
|
113
|
The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation.
|
Can J Microbiol
|
2007
|
0.78
|
114
|
Purification and properties of pi-repressible acid phosphatases from Aspergillus nidulans.
|
Phytochemistry
|
1998
|
0.78
|
115
|
Emerging drugs targeting PD-1 and PD-L1: reality or hope?
|
Expert Opin Emerg Drugs
|
2014
|
0.78
|
116
|
Combination of radiotherapy and targeted therapies in the treatment of locally advanced non-small cell lung cancer.
|
Target Oncol
|
2011
|
0.78
|
117
|
The Microsporum canis genome is organized into five chromosomes based on evidence from electrophoretic karyotyping and chromosome end mapping.
|
Med Mycol
|
2012
|
0.78
|
118
|
RNA-sequencing analysis of Trichophyton rubrum transcriptome in response to sublethal doses of acriflavine.
|
BMC Genomics
|
2014
|
0.78
|
119
|
Safety profile of erlotinib in patients with advanced non-small cell lung cancer with chronic renal failure.
|
J Thorac Oncol
|
2007
|
0.78
|
120
|
Over-expression of genes coding for proline oxidase, riboflavin kinase, cytochrome c oxidase and an MFS transporter induced by acriflavin in Trichophyton rubrum.
|
Med Mycol
|
2008
|
0.78
|
121
|
Transcription of Aspergillus nidulans pacC is modulated by alternative RNA splicing of palB.
|
FEBS Lett
|
2011
|
0.78
|
122
|
Quality of life analysis of TORCH, a randomized trial testing first-line erlotinib followed by second-line cisplatin/gemcitabine chemotherapy in advanced non-small-cell lung cancer.
|
J Thorac Oncol
|
2012
|
0.77
|
123
|
The role of targeted therapy in non-small cell lung cancer.
|
Crit Rev Oncol Hematol
|
2004
|
0.77
|
124
|
Treatment of severe post-traumatic bone defects with autologous stem cells loaded on allogeneic scaffolds.
|
Surg Technol Int
|
2012
|
0.77
|
125
|
Italian Survey on adjuvant treatment of non-small cell lung cancer (ISA).
|
Lung Cancer
|
2010
|
0.77
|
126
|
Thalidomide in small-cell lung cancer: is it a tombstone?
|
J Clin Oncol
|
2008
|
0.77
|
127
|
Should KRAS mutations be considered an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab?
|
J Clin Oncol
|
2008
|
0.77
|
128
|
The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer.
|
Curr Genomics
|
2008
|
0.77
|
129
|
Evaluation of ALK gene status in primary lung adenocarcinoma and matched metastases.
|
J Thorac Oncol
|
2011
|
0.77
|
130
|
In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation.
|
Biochem J
|
2006
|
0.77
|
131
|
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis.
|
Clin Chim Acta
|
2011
|
0.77
|
132
|
The PARAMOUNT trial: a phase III randomized study of maintenance pemetrexed versus placebo immediately following induction first-line treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small cell lung cancer.
|
Rev Recent Clin Trials
|
2013
|
0.77
|
133
|
Isolation of transcripts overexpressed in the human pathogen Trichophyton rubrum grown in lipid as carbon source.
|
Can J Microbiol
|
2011
|
0.77
|
134
|
Irreversible EGFR inhibitors in the treatment of advanced NSCLC.
|
Curr Pharm Des
|
2014
|
0.76
|
135
|
Phase I-II trial of gemcitabine-based first-line chemotherapies for small cell lung cancer in elderly patients with performance status 0-2: the G-STEP trial.
|
J Thorac Oncol
|
2012
|
0.76
|
136
|
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue.
|
PLoS One
|
2013
|
0.76
|
137
|
Altered signaling in the G1 phase deregulates chondrocyte growth in a mouse model with proteoglycan undersulfation.
|
J Cell Biochem
|
2014
|
0.76
|
138
|
Chemotherapy of advanced NSCLC in the elderly.
|
Tumori
|
2002
|
0.76
|
139
|
Carboplatin plus vinorelbine plus G-CSF in elderly patients with extensive-stage small-cell lung cancer: a poorly tolerated regimen. Results of a multicentre phase II study.
|
Lung Cancer
|
2002
|
0.76
|
140
|
Insights from a transgenic mouse model on the role of SLC26A2 in health and disease.
|
Novartis Found Symp
|
2006
|
0.76
|
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